SK284352B6 - Spôsob enzymatickej syntézy chirálnych amínov - Google Patents

Spôsob enzymatickej syntézy chirálnych amínov Download PDF

Info

Publication number
SK284352B6
SK284352B6 SK1338-2000A SK13382000A SK284352B6 SK 284352 B6 SK284352 B6 SK 284352B6 SK 13382000 A SK13382000 A SK 13382000A SK 284352 B6 SK284352 B6 SK 284352B6
Authority
SK
Slovakia
Prior art keywords
amino
aminopropane
acid
transaminase
chiral
Prior art date
Application number
SK1338-2000A
Other languages
English (en)
Slovak (sk)
Other versions
SK13382000A3 (sk
Inventor
Wei Wu
Mohit B. Bhatia
Craig M. Lewis
Wei Lang
Alice Wang
George W. Matcham
Original Assignee
Celgro
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celgro filed Critical Celgro
Publication of SK13382000A3 publication Critical patent/SK13382000A3/sk
Publication of SK284352B6 publication Critical patent/SK284352B6/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/001—Amines; Imines
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/005—Amino acids other than alpha- or beta amino acids, e.g. gamma amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/06—Alanine; Leucine; Isoleucine; Serine; Homoserine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/12—Methionine; Cysteine; Cystine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/006—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SK1338-2000A 1998-03-11 1999-03-10 Spôsob enzymatickej syntézy chirálnych amínov SK284352B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7752098P 1998-03-11 1998-03-11
PCT/US1999/005150 WO1999046398A1 (en) 1998-03-11 1999-03-10 Improvements in the enzymatic synthesis of chiral amines

Publications (2)

Publication Number Publication Date
SK13382000A3 SK13382000A3 (sk) 2001-05-10
SK284352B6 true SK284352B6 (sk) 2005-02-04

Family

ID=22138554

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1338-2000A SK284352B6 (sk) 1998-03-11 1999-03-10 Spôsob enzymatickej syntézy chirálnych amínov

Country Status (24)

Country Link
EP (1) EP1075534B8 (zh)
JP (1) JP2002505884A (zh)
KR (1) KR20010034561A (zh)
CN (1) CN1154746C (zh)
AT (1) ATE295424T1 (zh)
AU (1) AU753904B2 (zh)
BR (1) BR9908797A (zh)
CA (1) CA2322605A1 (zh)
CZ (1) CZ295882B6 (zh)
DE (1) DE69925267T2 (zh)
ES (1) ES2243051T3 (zh)
FI (1) FI20001805A (zh)
HK (1) HK1035000A1 (zh)
HU (1) HUP0101056A3 (zh)
MX (1) MXPA00008573A (zh)
NO (1) NO319671B1 (zh)
NZ (1) NZ506405A (zh)
PL (1) PL342882A1 (zh)
PT (1) PT1075534E (zh)
RU (1) RU2213142C2 (zh)
SK (1) SK284352B6 (zh)
TR (1) TR200002604T2 (zh)
UA (1) UA64784C2 (zh)
WO (1) WO1999046398A1 (zh)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1038953B1 (en) 1999-03-19 2004-09-22 Sumitomo Chemical Company, Limited Stereoselective transaminase, gene encoding said protein and use thereof
JP2001190298A (ja) * 2000-01-13 2001-07-17 Kanegafuchi Chem Ind Co Ltd 光学活性ｎ−メチルアミノ酸の製造方法
EP1818411A1 (en) * 2006-02-13 2007-08-15 Lonza AG Process for the preparation of optically active chiral amines
DE102007042600A1 (de) 2007-09-07 2009-03-12 Evonik Degussa Gmbh Verfahren zur Herstellung von enantiomerenangereichten Aminen
EP3354727B1 (en) 2009-01-08 2020-10-07 Codexis, Inc. Transaminase polypeptides
CN102405281B (zh) 2009-02-26 2015-05-13 科德克希思公司 转氨酶生物催化剂
EP2446026B1 (en) 2009-06-22 2017-08-09 Codexis, Inc. Transaminase reactions
CA2772426A1 (en) * 2009-09-02 2011-03-10 Lonza Ag A process for the identification and preparation of a (r)-specific omega-transaminase
DK2582799T3 (en) 2010-06-17 2018-02-12 Codexis Inc BIOCATALATORS AND PROCEDURES FOR THE SYNTHESIS OF (S) -3- (1-AMINOETHYL) -PHENOL
US8932836B2 (en) 2010-08-16 2015-01-13 Codexis, Inc. Biocatalysts and methods for the synthesis of (1R,2R)-2-(3,4-dimethoxyphenethoxy)cyclohexanamine
EP2744908A4 (en) * 2011-08-16 2015-05-27 Embio Ltd ENZYMATIC SYNTHESIS OF OPTICALLY ACTIVE CHIRAL AMINES
CN104630170A (zh) * 2013-11-08 2015-05-20 中国科学院天津工业生物技术研究所 一种来源于里氏木霉的新(r)-转氨酶及其应用
CN114134126B (zh) * 2021-10-28 2023-12-05 浙江大学杭州国际科创中心 转氨酶及其突变体在制备(s)-1-甲氧基-2-丙胺中的应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5300437A (en) * 1989-06-22 1994-04-05 Celgene Corporation Enantiomeric enrichment and stereoselective synthesis of chiral amines
DE69635082T2 (de) * 1995-10-23 2006-06-01 Kaneka Corp. Verfahren zur herstellung optisch aktiver aminoverbindungen

Also Published As

Publication number Publication date
WO1999046398A1 (en) 1999-09-16
CN1154746C (zh) 2004-06-23
DE69925267T2 (de) 2006-01-26
JP2002505884A (ja) 2002-02-26
CZ20003177A3 (cs) 2000-12-13
EP1075534A4 (en) 2003-07-09
CA2322605A1 (en) 1999-09-16
AU2993899A (en) 1999-09-27
PL342882A1 (en) 2001-07-16
FI20001805A (fi) 2000-08-15
CN1292828A (zh) 2001-04-25
NZ506405A (en) 2003-08-29
TR200002604T2 (tr) 2000-11-21
BR9908797A (pt) 2000-12-12
AU753904B2 (en) 2002-10-31
RU2213142C2 (ru) 2003-09-27
EP1075534B1 (en) 2005-05-11
NO20004036D0 (no) 2000-08-11
EP1075534B8 (en) 2005-07-06
KR20010034561A (ko) 2001-04-25
NO319671B1 (no) 2005-09-05
ES2243051T3 (es) 2005-11-16
HUP0101056A2 (hu) 2001-07-30
UA64784C2 (en) 2004-03-15
SK13382000A3 (sk) 2001-05-10
NO20004036L (no) 2000-10-27
HK1035000A1 (en) 2001-11-09
EP1075534A1 (en) 2001-02-14
PT1075534E (pt) 2005-09-30
CZ295882B6 (cs) 2005-11-16
MXPA00008573A (es) 2003-07-14
DE69925267D1 (de) 2005-06-16
ATE295424T1 (de) 2005-05-15
HUP0101056A3 (en) 2006-03-28

Similar Documents

Publication Publication Date Title
RU2087536C1 (ru) Способ энантиомерного обогащения смеси двух энантиомерных хиральных аминов
US8728750B2 (en) Process for preparation of optically active N-protected 3-aminopyrrolidine or optically active N-protected 3-aminopiperidine and the corresponding ketones by optical resolution of the racemic amine mixtures employing a bacterial omega-transaminase
US5300437A (en) Enantiomeric enrichment and stereoselective synthesis of chiral amines
SK284352B6 (sk) Spôsob enzymatickej syntézy chirálnych amínov
EP1818411A1 (en) Process for the preparation of optically active chiral amines
US5516660A (en) Microorganisms, their use and method of producing L-α-amino acids
JPS63500004A (ja) 光学活性な有機化合物の調整方法
JPS63500983A (ja) 結合アミノトランスフェラ−ゼを用いたアミノ酸の合成
US6133018A (en) Enzymatic synthesis of chiral amines using -2-amino propane as amine donor
US20010031487A1 (en) Process for producing optically active amino compounds
Winkler et al. Principles and results of stable isotope labelling of L-α-Aminoacids by combined chemical and enzymatic methods
CZ355697A3 (cs) Způsob stereoselektivní syntézy jedné chirální formy aminu
JPH02124087A (ja) シユードモナス属細菌の培養方法
JPS59159789A (ja) Ｌ−α−アミノ酸の製造方法
Tanaka et al. Synthesis of Amino Acids with Pyridoxal 5'-phosphate Enzymes (Commemoration Issue Dedicated to Professor Yuzo Inouye on the Occasion of his Retirement)
SK280218B6 (sk) Spôsob enantiomérneho obohacovania a stereoselektí