SI9600053B - Substituted benzensulphonyl ureas and thioureas, process for the preparation thereof and use thereof for the preparation of pharmaceutical preparations as well as pharmaceutical preparations containing them - Google Patents

Substituted benzensulphonyl ureas and thioureas, process for the preparation thereof and use thereof for the preparation of pharmaceutical preparations as well as pharmaceutical preparations containing them Download PDF

Info

Publication number: SI9600053B
Authority: SI; Slovenia
Prior art keywords: atoms; alkyl; cycloalkyl; carbon atoms; replaced
Prior art date: 1995-02-21

Application number

SI9600053A

Other languages

English (en)

Slovenian (sl)

Other versions

SI9600053A (en

Inventor

Heinrich Englert

Uwe Gerlach

Dieter Mania

Heinz Goegelein

Joachim Kaiser

Original Assignee

Hoechst Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-02-21

Filing date

1996-02-20

Publication date

2001-12-31

1996-02-20 Application filed by Hoechst Ag filed Critical Hoechst Ag

1996-12-31 Publication of SI9600053A publication Critical patent/SI9600053A/sl

2001-12-31 Publication of SI9600053B publication Critical patent/SI9600053B/sl

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/50—Compounds containing any of the groups, X being a hetero atom, Y being any atom
- C07C311/52—Y being a hetero atom
- C07C311/54—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea
- C07C311/57—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea having sulfur atoms of the sulfonylurea groups bound to carbon atoms of six-membered aromatic rings
- C07C311/58—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea having sulfur atoms of the sulfonylurea groups bound to carbon atoms of six-membered aromatic rings having nitrogen atoms of the sulfonylurea groups bound to hydrogen atoms or to acyclic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/48—Compounds containing oxirane rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. ester or nitrile radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C335/40—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of thiourea or isothiourea groups further bound to other hetero atoms
- C07C335/42—Sulfonylthioureas; Sulfonylisothioureas
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Hospice & Palliative Care (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Epoxy Compounds (AREA)

SI9600053A 1995-02-21 1996-02-20 Substituted benzensulphonyl ureas and thioureas, process for the preparation thereof and use thereof for the preparation of pharmaceutical preparations as well as pharmaceutical preparations containing them SI9600053B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19505910A DE19505910A1 (de)	1995-02-21	1995-02-21	Substituierte Benzolsulfonylharnstoffe und -thioharnstoffe, Verfahren zu ihrer Herstellung, ihre Verwendung zur Herstellung pharmazeutischer Präparate und sie enthaltende Medikamente

Publications (2)

Publication Number	Publication Date
SI9600053A SI9600053A (en)	1996-12-31
SI9600053B true SI9600053B (en)	2001-12-31

Family

ID=7754593

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SI9600053A SI9600053B (en)	1995-02-21	1996-02-20	Substituted benzensulphonyl ureas and thioureas, process for the preparation thereof and use thereof for the preparation of pharmaceutical preparations as well as pharmaceutical preparations containing them

Country Status (30)

Country	Link
US (1)	US5633239A (es)
EP (1)	EP0728741B1 (es)
JP (1)	JP3905570B2 (es)
KR (1)	KR100446566B1 (es)
CN (1)	CN1060767C (es)
AR (1)	AR001352A1 (es)
AT (1)	ATE196467T1 (es)
AU (1)	AU701278B2 (es)
BR (1)	BR9600773A (es)
CA (1)	CA2169695C (es)
CZ (1)	CZ291219B6 (es)
DE (2)	DE19505910A1 (es)
DK (1)	DK0728741T3 (es)
ES (1)	ES2151614T3 (es)
FI (1)	FI120392B (es)
GR (1)	GR3034646T3 (es)
HR (1)	HRP960081B1 (es)
HU (1)	HU227308B1 (es)
IL (1)	IL117179A (es)
MY (1)	MY113432A (es)
NO (1)	NO305792B1 (es)
NZ (1)	NZ286013A (es)
PL (1)	PL181628B1 (es)
PT (1)	PT728741E (es)
RU (1)	RU2159763C2 (es)
SI (1)	SI9600053B (es)
SK (1)	SK281876B6 (es)
TR (1)	TR199600129A2 (es)
TW (1)	TW357140B (es)
ZA (1)	ZA961314B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE19832009A1 (de)	1998-07-16	2000-01-20	Hoechst Marion Roussel De Gmbh	2,5-Substituierte Benzolsulfonylharnstoffe und -thioharnstoffe, Verfahren zu ihrer Herstellung, ihre Verwendung und sie enthaltende pharamazeutische Präparate
US6436864B1 (en)	1999-10-06	2002-08-20	Sri International	Unsaturated nitrogenous compounds as electron donors for use with ziegler-natta catalysts
DE10129704A1 (de) *	2001-06-22	2003-01-02	Aventis Pharma Gmbh	Verwendung von Benzolsulfonyl(thio)harnstoffen in der Behandlung des septischen Schocks
CA2601508C (en) *	2005-03-17	2012-01-03	Pfizer, Inc.	Cyclopropanecarboxamide derivatives

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE1198354B (de) *	1963-09-25	1965-08-12	Hoechst Ag	Verfahren zur Herstellung von Benzol-sulfonylharnstoffen
NL141381B (nl) *	1963-09-25	1974-03-15	Hoechst Ag	Werkwijze voor het bereiden van geneesmiddelen met bloedsuikerspiegel verlagende werkzaamheid.
BE754454A (fr) *	1969-08-06	1971-02-05	Bayer Ag	Nouveaux composes hypoglycemiques du type d'arylsulfonylurees et d'arylsulfonylsemicarbazides contenant des groupes carbonamide
ES2098069T3 (es) *	1993-02-23	1997-04-16	Hoechst Ag	Bencenosulfonil-ureas y -tioureas sustituidas, procedimiento para su preparacion y su utilizacion como agentes farmaceuticos.
DE4341655A1 (de) *	1993-12-07	1995-06-08	Hoechst Ag	Aminosubstituierte Benzolsulfonylharnstoffe und -thioharnstoffe, Verfahren zu ihrer Herstellung und ihre Verwendung als Pharmazeutika

1994
- 1994-02-20 ZA ZA961314A patent/ZA961314B/xx unknown
1995
- 1995-02-21 DE DE19505910A patent/DE19505910A1/de not_active Withdrawn
- 1995-12-29 HU HU9503931A patent/HU227308B1/hu not_active IP Right Cessation
1996
- 1996-01-29 PL PL96312529A patent/PL181628B1/pl not_active IP Right Cessation
- 1996-02-13 CN CN96102002A patent/CN1060767C/zh not_active Expired - Fee Related
- 1996-02-15 ES ES96102255T patent/ES2151614T3/es not_active Expired - Lifetime
- 1996-02-15 DK DK96102255T patent/DK0728741T3/da active
- 1996-02-15 AT AT96102255T patent/ATE196467T1/de active
- 1996-02-15 PT PT96102255T patent/PT728741E/pt unknown
- 1996-02-15 EP EP96102255A patent/EP0728741B1/de not_active Expired - Lifetime
- 1996-02-15 DE DE59605898T patent/DE59605898D1/de not_active Expired - Lifetime
- 1996-02-16 CA CA002169695A patent/CA2169695C/en not_active Expired - Fee Related
- 1996-02-16 BR BR9600773A patent/BR9600773A/pt not_active IP Right Cessation
- 1996-02-16 US US08/601,109 patent/US5633239A/en not_active Expired - Lifetime
- 1996-02-16 TR TR96/00129A patent/TR199600129A2/xx unknown
- 1996-02-17 MY MYPI96000635A patent/MY113432A/en unknown
- 1996-02-19 AR AR33545296A patent/AR001352A1/es unknown
- 1996-02-19 IL IL11717996A patent/IL117179A/xx not_active IP Right Cessation
- 1996-02-19 HR HR960081A patent/HRP960081B1/xx not_active IP Right Cessation
- 1996-02-19 FI FI960740A patent/FI120392B/fi not_active IP Right Cessation
- 1996-02-19 SK SK222-96A patent/SK281876B6/sk not_active IP Right Cessation
- 1996-02-19 CZ CZ1996486A patent/CZ291219B6/cs not_active IP Right Cessation
- 1996-02-19 AU AU45600/96A patent/AU701278B2/en not_active Ceased
- 1996-02-19 NZ NZ286013A patent/NZ286013A/en not_active IP Right Cessation
- 1996-02-20 NO NO960664A patent/NO305792B1/no not_active IP Right Cessation
- 1996-02-20 RU RU96103250/04A patent/RU2159763C2/ru not_active IP Right Cessation
- 1996-02-20 SI SI9600053A patent/SI9600053B/sl not_active IP Right Cessation
- 1996-02-21 KR KR1019960004021A patent/KR100446566B1/ko not_active IP Right Cessation
- 1996-02-21 JP JP03327496A patent/JP3905570B2/ja not_active Expired - Fee Related
- 1996-04-22 TW TW085104747A patent/TW357140B/zh not_active IP Right Cessation
2000
- 2000-10-20 GR GR20000402333T patent/GR3034646T3/el unknown

Also Published As

Publication number	Publication date
NO960664D0 (no)	1996-02-20
GR3034646T3 (en)	2001-01-31
HU227308B1 (en)	2011-03-28
SK22296A3 (en)	1996-10-02
ZA961314B (en)	1996-08-27
CA2169695A1 (en)	1996-08-22
NO305792B1 (no)	1999-07-26
NZ286013A (en)	1996-10-28
CN1134932A (zh)	1996-11-06
AU4560096A (en)	1996-08-29
FI960740A (fi)	1996-08-22
TR199600129A2 (tr)	1996-10-21
AU701278B2 (en)	1999-01-21
AR001352A1 (es)	1997-10-22
DE19505910A1 (de)	1996-08-22
SI9600053A (en)	1996-12-31
PL312529A1 (en)	1996-09-02
NO960664L (no)	1996-08-22
TW357140B (en)	1999-05-01
KR100446566B1 (ko)	2004-12-03
RU2159763C2 (ru)	2000-11-27
MY113432A (en)	2002-02-28
DK0728741T3 (da)	2000-12-18
HUT73974A (en)	1996-10-28
HRP960081B1 (en)	2001-08-31
HU9503931D0 (en)	1996-03-28
SK281876B6 (sk)	2001-08-06
HRP960081A2 (en)	1997-10-31
CN1060767C (zh)	2001-01-17
PL181628B1 (pl)	2001-08-31
CA2169695C (en)	2008-05-20
KR960031429A (ko)	1996-09-17
US5633239A (en)	1997-05-27
JPH08245555A (ja)	1996-09-24
CZ291219B6 (cs)	2003-01-15
CZ48696A3 (en)	1996-09-11
FI120392B (fi)	2009-10-15
EP0728741A1 (de)	1996-08-28
EP0728741B1 (de)	2000-09-20
ATE196467T1 (de)	2000-10-15
BR9600773A (pt)	1997-12-23
DE59605898D1 (de)	2000-10-26
FI960740A0 (fi)	1996-02-19
PT728741E (pt)	2001-03-30
IL117179A (en)	2000-02-17
IL117179A0 (en)	1996-06-18
ES2151614T3 (es)	2001-01-01
JP3905570B2 (ja)	2007-04-18

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SI9600053B (en)	2001-12-31	Substituted benzensulphonyl ureas and thioureas, process for the preparation thereof and use thereof for the preparation of pharmaceutical preparations as well as pharmaceutical preparations containing them
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SI9600040B (en)	2001-12-31	Substituted benzensulphonyl ureas and thioureas, process for the preparation thereof and use thereof for the preparation of pharmaceutical preparations as well as pharmaceutical preparations containing them

Legal Events

Date	Code	Title	Description
2005-01-10	IF	Valid on the event date
2012-11-30	KO00	Lapse of patent	Effective date: 20121015