SI9011710B - 13-alkil-23-imino in 13-halo-23-imino derivati makrolidnih spojin - Google Patents

13-alkil-23-imino in 13-halo-23-imino derivati makrolidnih spojin Download PDF

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Publication number
SI9011710B
SI9011710B SI9011710A SI9011710A SI9011710B SI 9011710 B SI9011710 B SI 9011710B SI 9011710 A SI9011710 A SI 9011710A SI 9011710 A SI9011710 A SI 9011710A SI 9011710 B SI9011710 B SI 9011710B
Authority
SI
Slovenia
Prior art keywords
alkyl
hydrogen
methyl
isopropyl
ethyl
Prior art date
Application number
SI9011710A
Other languages
English (en)
Slovenian (sl)
Other versions
SI9011710A (sl
Inventor
Brian Lee Buckwalter
Shin-Shyong Tseng
Timothy Claude Barden
Original Assignee
American Cyanamid Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/405,808 external-priority patent/US5030650A/en
Priority claimed from US07/455,686 external-priority patent/US5055486A/en
Application filed by American Cyanamid Company filed Critical American Cyanamid Company
Publication of SI9011710A publication Critical patent/SI9011710A/sl
Publication of SI9011710B publication Critical patent/SI9011710B/sl

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/22—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains four or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pest Control & Pesticides (AREA)
  • Genetics & Genomics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Agronomy & Crop Science (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SI9011710A 1989-09-11 1990-09-10 13-alkil-23-imino in 13-halo-23-imino derivati makrolidnih spojin SI9011710B (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US07/405,808 US5030650A (en) 1989-09-11 1989-09-11 13-halo-23-imino derivatives of LL-F28249 compounds and their use as endo- and ectoparasiticidal, insecticidal, acaricidal and nematocidal agents
US07/455,686 US5055486A (en) 1989-12-22 1989-12-22 13-alkyl-23-imino derivative of LL-F28249 compounds and their use as endo- and ectoparasiticidal, insecticidal, acaricidal and nematocidal agents
YU171090A YU47592B (sh) 1989-09-11 1990-09-10 13-alkil-23-imino i 13-halo-23-imino derivati makrolidnih jedinjenja

Publications (2)

Publication Number Publication Date
SI9011710A SI9011710A (sl) 1998-02-28
SI9011710B true SI9011710B (sl) 2000-12-31

Family

ID=27019245

Family Applications (1)

Application Number Title Priority Date Filing Date
SI9011710A SI9011710B (sl) 1989-09-11 1990-09-10 13-alkil-23-imino in 13-halo-23-imino derivati makrolidnih spojin

Country Status (21)

Country Link
EP (1) EP0423445B1 (pt)
JP (1) JP3026827B2 (pt)
KR (2) KR0160972B1 (pt)
CN (2) CN1032004C (pt)
AT (1) ATE130006T1 (pt)
AU (1) AU631454B2 (pt)
BG (1) BG60271B1 (pt)
BR (1) BR9004494A (pt)
DE (1) DE69023454T2 (pt)
DK (1) DK0423445T3 (pt)
ES (1) ES2081880T3 (pt)
GR (1) GR3018033T3 (pt)
HU (1) HU217357B (pt)
IE (1) IE71210B1 (pt)
IL (1) IL109791A (pt)
PL (1) PL164168B1 (pt)
PT (1) PT95241B (pt)
RU (1) RU2070885C1 (pt)
SI (1) SI9011710B (pt)
UA (1) UA41246C2 (pt)
YU (1) YU47592B (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4988824A (en) * 1989-09-11 1991-01-29 Maulding Donald R Process for the preparation of 23-(C1-C6 alkyloxime)-LL-F28249 compounds
US5229416A (en) * 1992-04-29 1993-07-20 Merck & Co., Inc. Avermectin difluoro derivatives
DE19654079A1 (de) 1996-12-23 1998-06-25 Bayer Ag Endo-ekto-parasitizide Mittel
DE102004053964A1 (de) 2004-11-09 2006-05-11 Bayer Healthcare Ag Mittel gegen Demodikose
CN106831811B (zh) * 2015-08-12 2018-10-26 内蒙古佳瑞米精细化工有限公司 一种制备高含量尼莫克汀的方法
US20210137960A1 (en) 2018-02-01 2021-05-13 Yale University Compositions and methods for inhibition of nuclear-penetrating antibodies

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ221077A (en) * 1986-07-18 1990-06-26 Ciba Geigy Ag 13b-alkyl milbemycins and use as parasiticides
ATE109783T1 (de) * 1986-09-12 1994-08-15 American Cyanamid Co 23-oxo(keto) und 23-imino-derivate von ll-f28249- verbindungen.
US4831016A (en) * 1986-10-31 1989-05-16 Merck & Co., Inc. Reduced avermectin derivatives
US4886829A (en) * 1987-03-06 1989-12-12 American Cyanamid Company 23-Oxo (keto) and 23-imino derivatives of mono- and diepoxy LL-F28249 compounds
US4806527A (en) * 1987-03-16 1989-02-21 Merck & Co., Inc. Avermectin derivatives
US5830875A (en) * 1989-10-30 1998-11-03 Merck & Co., Inc. 24-and 25-substituted avermectin and milbemycin derivatives

Also Published As

Publication number Publication date
AU631454B2 (en) 1992-11-26
RU2070885C1 (ru) 1996-12-27
EP0423445A1 (en) 1991-04-24
JPH03106886A (ja) 1991-05-07
CN1053556C (zh) 2000-06-21
HU217357B (hu) 2000-01-28
SI9011710A (sl) 1998-02-28
PL164168B1 (pl) 1994-06-30
PT95241B (pt) 1997-06-30
KR0160972B1 (ko) 1998-12-01
GR3018033T3 (en) 1996-02-29
KR0168751B1 (ko) 1999-01-15
CN1032004C (zh) 1996-06-12
KR910006491A (ko) 1991-04-29
ES2081880T3 (es) 1996-03-16
CN1050193A (zh) 1991-03-27
DE69023454T2 (de) 1996-06-05
IL109791A (en) 1996-06-18
YU47592B (sh) 1995-10-24
JP3026827B2 (ja) 2000-03-27
HUT54691A (en) 1991-03-28
BR9004494A (pt) 1991-09-10
PT95241A (pt) 1991-06-25
DK0423445T3 (da) 1995-12-11
YU171090A (sh) 1992-12-21
IE71210B1 (en) 1997-02-12
CN1115600A (zh) 1996-01-31
PL286823A1 (en) 1991-10-07
EP0423445B1 (en) 1995-11-08
IE903274A1 (en) 1991-03-27
AU6235790A (en) 1991-03-14
ATE130006T1 (de) 1995-11-15
DE69023454D1 (de) 1995-12-14
BG60271B2 (bg) 1994-03-31
UA41246C2 (uk) 2001-09-17
BG60271B1 (bg) 1994-03-31

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Effective date: 20050610