SI3592393T1 - Sprostljivi konjugati - Google Patents
Sprostljivi konjugatiInfo
- Publication number
- SI3592393T1 SI3592393T1 SI201830575T SI201830575T SI3592393T1 SI 3592393 T1 SI3592393 T1 SI 3592393T1 SI 201830575 T SI201830575 T SI 201830575T SI 201830575 T SI201830575 T SI 201830575T SI 3592393 T1 SI3592393 T1 SI 3592393T1
- Authority
- SI
- Slovenia
- Prior art keywords
- releasable conjugates
- conjugates
- releasable
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/26—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/548—Phosphates or phosphonates, e.g. bone-seeking
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/549—Sugars, nucleosides, nucleotides or nucleic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Child & Adolescent Psychology (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Emergency Medicine (AREA)
- Pulmonology (AREA)
- Biophysics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Polyethers (AREA)
- Enzymes And Modification Thereof (AREA)
- Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201762469989P | 2017-03-10 | 2017-03-10 | |
US201762564820P | 2017-09-28 | 2017-09-28 | |
PCT/IB2018/051579 WO2018163131A1 (en) | 2017-03-10 | 2018-03-10 | Releasable conjugates |
EP18713014.1A EP3592393B1 (en) | 2017-03-10 | 2018-03-10 | Releasable conjugates |
Publications (1)
Publication Number | Publication Date |
---|---|
SI3592393T1 true SI3592393T1 (sl) | 2022-04-29 |
Family
ID=61764062
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI201830575T SI3592393T1 (sl) | 2017-03-10 | 2018-03-10 | Sprostljivi konjugati |
Country Status (11)
Country | Link |
---|---|
US (2) | US11786599B2 (sl) |
EP (2) | EP4011396A1 (sl) |
JP (2) | JP7152408B2 (sl) |
KR (1) | KR20190125310A (sl) |
CN (1) | CN110545850A (sl) |
AU (2) | AU2018231832A1 (sl) |
BR (1) | BR112019017103A2 (sl) |
CA (1) | CA3051173A1 (sl) |
DK (1) | DK3592393T3 (sl) |
SI (1) | SI3592393T1 (sl) |
WO (1) | WO2018163131A1 (sl) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
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JP7152408B2 (ja) | 2017-03-10 | 2022-10-12 | キアペグ ファーマシューティカルズ アクチエボラグ | 遊離可能コンジュゲート |
JP2021515765A (ja) | 2018-03-09 | 2021-06-24 | キアペグ ファーマシューティカルズ アクチエボラグ | 放出可能な抗体コンジュゲート |
BR112021004689A2 (pt) | 2018-09-12 | 2021-06-08 | Quiapeg Pharmaceuticals Ab | conjugados glp-1 liberáveis |
CN111175387B (zh) * | 2018-11-13 | 2022-06-07 | 成都康弘药业集团股份有限公司 | 一种米那普仑异构体的检测方法 |
US10768173B1 (en) | 2019-09-06 | 2020-09-08 | Element Biosciences, Inc. | Multivalent binding composition for nucleic acid analysis |
CN112168820B (zh) * | 2019-07-05 | 2023-09-29 | 中国科学院生物物理研究所 | SRCAP ATPase抑制剂在结直肠癌治疗中的应用 |
US11287422B2 (en) | 2019-09-23 | 2022-03-29 | Element Biosciences, Inc. | Multivalent binding composition for nucleic acid analysis |
KR102398574B1 (ko) | 2019-10-10 | 2022-05-13 | 주식회사 엘지에너지솔루션 | 전지 모듈 및 이를 포함하는 전지 팩 |
CN110946844A (zh) * | 2019-12-11 | 2020-04-03 | 正大制药(青岛)有限公司 | 一种含有艾地骨化醇的复方控释制剂 |
CN113456824B (zh) * | 2020-03-31 | 2023-03-31 | 四川大学华西医院 | 一种抗肿瘤载药纳米复合材料 |
AU2021319863A1 (en) | 2020-08-05 | 2023-02-16 | Ascendis Pharma A/S | Conjugates comprising reversible linkers and uses thereof |
CN112138170B (zh) * | 2020-09-28 | 2022-05-20 | 广东药科大学 | 一种预防顺铂药源性聋的缀合物及其制备方法和应用 |
CN112316156B (zh) * | 2020-10-27 | 2022-03-15 | 四川大学 | 具抗氧化和抗菌性的胶原蛋白修复膜、其制备方法及应用 |
CN112402620A (zh) * | 2020-12-07 | 2021-02-26 | 南开大学 | 肿瘤微环境还原响应性的纳米药物及其制备方法 |
CN112457383B (zh) * | 2020-12-16 | 2022-06-17 | 阿南达 | 一种多肽、制备方法及其医药用途 |
CN112516285B (zh) * | 2020-12-18 | 2022-09-02 | 中南大学 | 一种预防或治疗缺血/再灌注损伤的药物组合物及应用 |
CN112574272B (zh) * | 2020-12-25 | 2021-09-21 | 中国医学科学院药用植物研究所 | 一种灵芝酸a衍生物的制备及其应用 |
CN114478800B (zh) * | 2021-02-05 | 2022-10-11 | 华南理工大学 | 基于血清白蛋白的融合蛋白、纳米组装体及其制备方法和应用 |
CN112999196B (zh) * | 2021-03-03 | 2023-04-28 | 西安医学院 | 用于长效稳定释放的吗替麦考酚酯纳米制剂及其制备方法 |
CN113133989B (zh) * | 2021-03-09 | 2023-04-25 | 西安医学院 | 一种用于抗结核药物利福平的长效制剂及制备方法 |
CN114617876B (zh) * | 2022-01-28 | 2023-04-07 | 四川大学华西医院 | 一种抗肿瘤联合用药物 |
CN114886817B (zh) * | 2022-06-02 | 2023-06-27 | 杭州配方师科技有限公司 | 一种弗来歇氏柳叶菜和酵母菌锌发酵复合物、制备方法及应用 |
WO2023244517A1 (en) * | 2022-06-16 | 2023-12-21 | Merck Sharp & Dohme Llc | Interleukin-2 prodrugs |
KR102623104B1 (ko) * | 2023-08-23 | 2024-01-11 | 에프아이씨씨주식회사 | 보툴리눔톡신 결합체와 줄기세포 엑소좀 복합체를 유효성분으로 함유하는 피부 재생 및 주름 개선용 화장료 조성물 및 그의 제조 방법 |
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JP2021515765A (ja) | 2018-03-09 | 2021-06-24 | キアペグ ファーマシューティカルズ アクチエボラグ | 放出可能な抗体コンジュゲート |
BR112021004689A2 (pt) * | 2018-09-12 | 2021-06-08 | Quiapeg Pharmaceuticals Ab | conjugados glp-1 liberáveis |
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2018
- 2018-03-10 JP JP2019545923A patent/JP7152408B2/ja active Active
- 2018-03-10 CA CA3051173A patent/CA3051173A1/en active Pending
- 2018-03-10 KR KR1020197024541A patent/KR20190125310A/ko not_active Application Discontinuation
- 2018-03-10 EP EP21208889.2A patent/EP4011396A1/en active Pending
- 2018-03-10 DK DK18713014.1T patent/DK3592393T3/da active
- 2018-03-10 EP EP18713014.1A patent/EP3592393B1/en active Active
- 2018-03-10 CN CN201880014422.0A patent/CN110545850A/zh active Pending
- 2018-03-10 BR BR112019017103A patent/BR112019017103A2/pt active Search and Examination
- 2018-03-10 SI SI201830575T patent/SI3592393T1/sl unknown
- 2018-03-10 WO PCT/IB2018/051579 patent/WO2018163131A1/en active Application Filing
- 2018-03-10 AU AU2018231832A patent/AU2018231832A1/en not_active Abandoned
- 2018-03-12 US US15/918,944 patent/US11786599B2/en active Active
-
2022
- 2022-09-29 JP JP2022155899A patent/JP7381684B2/ja active Active
-
2023
- 2023-08-15 US US18/234,142 patent/US20230381323A1/en active Pending
-
2024
- 2024-02-26 AU AU2024201279A patent/AU2024201279A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
US20230381323A1 (en) | 2023-11-30 |
DK3592393T3 (da) | 2022-03-07 |
JP2022191304A (ja) | 2022-12-27 |
JP2020512302A (ja) | 2020-04-23 |
US20180360974A1 (en) | 2018-12-20 |
KR20190125310A (ko) | 2019-11-06 |
AU2024201279A1 (en) | 2024-03-21 |
EP3592393A1 (en) | 2020-01-15 |
EP3592393B1 (en) | 2021-12-01 |
EP4011396A1 (en) | 2022-06-15 |
BR112019017103A2 (pt) | 2020-04-14 |
US11786599B2 (en) | 2023-10-17 |
CN110545850A (zh) | 2019-12-06 |
WO2018163131A1 (en) | 2018-09-13 |
CA3051173A1 (en) | 2018-09-13 |
AU2018231832A1 (en) | 2019-08-08 |
JP7152408B2 (ja) | 2022-10-12 |
JP7381684B2 (ja) | 2023-11-15 |
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