SI3564357T1 - Bakterioterapija Clostridium Difficile colitisa - Google Patents

Bakterioterapija Clostridium Difficile colitisa

Info

Publication number
SI3564357T1
SI3564357T1 SI201132058T SI201132058T SI3564357T1 SI 3564357 T1 SI3564357 T1 SI 3564357T1 SI 201132058 T SI201132058 T SI 201132058T SI 201132058 T SI201132058 T SI 201132058T SI 3564357 T1 SI3564357 T1 SI 3564357T1
Authority
SI
Slovenia
Prior art keywords
bacteriotherapy
clostridium difficile
difficile colitis
colitis
clostridium
Prior art date
Application number
SI201132058T
Other languages
English (en)
Inventor
Edwin J. Hlavka
Original Assignee
Rebiotix, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rebiotix, Inc. filed Critical Rebiotix, Inc.
Publication of SI3564357T1 publication Critical patent/SI3564357T1/sl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/04Preserving or maintaining viable microorganisms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12Antidiarrhoeals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911Bacteria
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/33Assays involving biological materials from specific organisms or of a specific nature from bacteria from Clostridium (G)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
SI201132058T 2010-02-01 2011-02-01 Bakterioterapija Clostridium Difficile colitisa SI3564357T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US33728310P 2010-02-01 2010-02-01
US35118410P 2010-06-03 2010-06-03
EP19176151.9A EP3564357B1 (en) 2010-02-01 2011-02-01 Bacteriotherapy for clostridium difficile colitis

Publications (1)

Publication Number Publication Date
SI3564357T1 true SI3564357T1 (sl) 2022-09-30

Family

ID=44319684

Family Applications (1)

Application Number Title Priority Date Filing Date
SI201132058T SI3564357T1 (sl) 2010-02-01 2011-02-01 Bakterioterapija Clostridium Difficile colitisa

Country Status (14)

Country Link
US (7) US9629881B2 (sl)
EP (4) EP4032586A1 (sl)
AU (1) AU2011209940B2 (sl)
CA (1) CA2788558C (sl)
DK (1) DK3564357T3 (sl)
ES (3) ES2916399T3 (sl)
HR (1) HRP20220751T1 (sl)
HU (1) HUE059169T2 (sl)
LT (1) LT3564357T (sl)
PL (1) PL3564357T3 (sl)
PT (1) PT3564357T (sl)
RS (1) RS63299B1 (sl)
SI (1) SI3564357T1 (sl)
WO (1) WO2011094027A1 (sl)

Families Citing this family (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPQ899700A0 (en) 2000-07-25 2000-08-17 Borody, Thomas Julius Probiotic recolonisation therapy
PT3564357T (pt) 2010-02-01 2022-06-14 Rebiotix Inc Bacterioterapia para colite por clostridium difficile
WO2012016287A2 (en) * 2010-08-04 2012-02-09 Borody Thomas J Compositions for fecal floral transplantation and methods for making and using them and devices for deuvering them
EP3610881A1 (en) 2011-03-09 2020-02-19 Regents Of The University Of Minnesota Compositions and methods for transplantation of colon microbiota
US9176026B2 (en) 2011-12-15 2015-11-03 Pureflora, Inc. Device for the collection, refinement, and administration of gastrointestinal microflora
EP2850202B1 (en) * 2012-05-18 2020-03-11 Genome Research Limited Methods and groups
WO2013176774A1 (en) 2012-05-25 2013-11-28 Arizona Board Of Regents Microbiome markers and therapies for autism spectrum disorders
US8906668B2 (en) 2012-11-23 2014-12-09 Seres Health, Inc. Synergistic bacterial compositions and methods of production and use thereof
EP3904502A3 (en) 2013-02-04 2022-02-23 Seres Therapeutics, Inc. Compositions and methods
EP3584308A3 (en) 2013-02-04 2020-03-04 Seres Therapeutics, Inc. Compositions and methods
CA2906921A1 (en) 2013-03-15 2014-09-18 Seres Therapeutics, Inc. Network-based microbial compositions and methods
US9511100B2 (en) 2013-06-05 2016-12-06 Rebiotix, Inc. Microbiota restoration therapy (MRT), compositions and methods of manufacture
PL3003330T4 (pl) 2013-06-05 2019-03-29 Rebiotix, Inc. Terapia przywracająca mikrobiota (MRT), kompozycje i sposoby wytwarzania
US9511099B2 (en) 2013-06-05 2016-12-06 Rebiotix, Inc. Microbiota restoration therapy (MRT), compositions and methods of manufacture
US9694039B2 (en) 2013-06-05 2017-07-04 Rebiotix, Inc. Microbiota restoration therapy (MRT), compositions and methods of manufacture
US10383901B2 (en) 2013-06-05 2019-08-20 Rebiotix, Inc. Microbiota restoration therapy (MRT), compositions and methods of manufacture
US9782445B2 (en) 2013-06-05 2017-10-10 Rebiotix, Inc. Microbiota restoration therapy (MRT), compositions and methods of manufacture
MX367109B (es) 2013-11-25 2019-08-05 Seres Therapeutics Inc Composiciones bacterianas sinergicas y sus metodos de produccion y usos.
EP3082431A4 (en) 2013-12-16 2017-11-15 Seres Therapeutics, Inc. Bacterial compositions and methods of use thereof for treatment of immune system disorders
AU2016259871B2 (en) 2015-05-11 2020-04-16 Mybiotics Pharma Ltd Systems and methods for growing a biofilm of probiotic bacteria on solid particles for colonization of bacteria in the gut
EP3294307A4 (en) 2015-05-14 2019-01-23 Crestovo Holdings Llc COMPOSITIONS FOR TRANSPLANTATION OF FECAL FLORA AND METHODS OF PREPARATION AND USE THEREOF, AND DEVICES FOR THEIR ADMINISTRATION
JP6856968B2 (ja) 2015-05-22 2021-04-14 アリゾナ ボード オブ リージェンツ オン ビハーフ オブ アリゾナ ステート ユニバーシティ 自閉症スペクトラム障害および関連する症候を治療するための方法
US10799539B2 (en) 2015-06-09 2020-10-13 Rebiotix, Inc. Microbiota restoration therapy (MRT) compositions and methods of manufacture
US10828340B2 (en) 2015-06-09 2020-11-10 Rebiotix, Inc. Microbiota restoration therapy (MRT) compositions and methods of manufacture
ES2889902T3 (es) 2015-06-09 2022-01-14 Rebiotix Inc Métodos de fabricación de composiciones para terapia de restauración de la microbiota (TRM)
US10905726B2 (en) 2015-06-09 2021-02-02 Rebiotix, Inc. Microbiota restoration therapy (MRT) compositions and methods of manufacture
MX2018014419A (es) 2016-05-25 2019-04-11 Mybiotics Pharma Ltd Composicion y metodos para la terapia de microbiota.
US20170360848A1 (en) 2016-06-15 2017-12-21 Arizona Board Of Regents On Behalf Of Arizona State University Methods for treating autism spectrum disorder and associated symptoms
US10849936B2 (en) 2016-07-01 2020-12-01 Regents Of The University Of Minnesota Compositions and methods for C. difficile treatment
US20180036352A1 (en) 2016-08-03 2018-02-08 Crestovo Holdings Llc Methods for treating ulcerative colitis
US11959125B2 (en) 2016-09-15 2024-04-16 Sun Genomics, Inc. Universal method for extracting nucleic acid molecules from a diverse population of one or more types of microbes in a sample
MX2019003447A (es) 2016-09-27 2019-08-29 Univ Texas Metodos para mejorar la terapia de bloqueo del punto de control inmune mediante la modulacion del microbioma.
US11213549B2 (en) 2016-10-11 2022-01-04 Finch Therapeutics Holdings Llc Compositions and method for treating primary sclerosing cholangitis and related disorders
WO2018071537A1 (en) 2016-10-11 2018-04-19 Crestovo Holdings Llc Compositions and methods for treating multiple sclerosis and related disorders
US10092601B2 (en) 2016-10-11 2018-10-09 Crestovo Holdings Llc Compositions and methods for treating multiple sclerosis and related disorders
CA3058943C (en) 2017-04-03 2023-10-17 Gusto Global, Llc Rational design of microbial-based biotherapeutics
AU2018250206A1 (en) 2017-04-05 2019-10-31 Crestovo Holdings Llc Compositions and methods for treating parkinson's disease (PD) and related disorders
US11040073B2 (en) 2017-04-05 2021-06-22 Finch Therapeutics Holdings Llc Compositions and methods for treating diverticulitis and related disorders
JP2020521760A (ja) 2017-05-26 2020-07-27 クレストヴォ・ホールディングス・エルエルシー 糞便微生物ベースの治療剤を含む凍結乾燥組成物ならびにそれを製造および使用する方法
CA3072032A1 (en) 2017-08-07 2019-02-14 Finch Therapeutics, Inc. Compositions and methods for maintaining and restoring a healthy gut barrier
JP2020530840A (ja) 2017-08-14 2020-10-29 セレス セラピューティクス インコーポレイテッド 胆汁うっ滞性疾患を治療するための組成物及び方法
JP2020536548A (ja) 2017-10-13 2020-12-17 レビオティクス インコーポレイテッドRebiotix,Inc. マイクロバイオーム健康指数
WO2019213595A1 (en) 2018-05-04 2019-11-07 Ferring B.V. Microbiota restoration therapy (mrt) compositions and methods of manufacture
WO2019241523A1 (en) 2018-06-14 2019-12-19 Rebiotix, Inc. Microbiota restoration therapy (mrt) compositions and methods of manufacture
US11166990B2 (en) 2018-07-13 2021-11-09 Finch Therapeutics Holdings Llc Methods and compositions for treating ulcerative colitis
AU2019321681A1 (en) * 2018-08-17 2021-02-25 Vedanta Biosciences, Inc. Methods of decreasing dysbiosis and restoring a microbiome
WO2020069280A1 (en) 2018-09-27 2020-04-02 Crestovo Holdings Llc Compositions and methods for treating epilepsy and related disorders
JP2022517268A (ja) * 2019-01-16 2022-03-07 ボード オブ リージェンツ,ザ ユニバーシティ オブ テキサス システム 免疫チェックポイント阻害剤関連大腸炎を処置するための方法および組成物
WO2021096794A1 (en) * 2019-11-11 2021-05-20 Hazan Sabine Method of treating an individual with a health condition with fecal microbiota transplant
US11744866B2 (en) 2020-03-18 2023-09-05 Sabine Hazan Methods of preventing and treating COVID-19 infection with probiotics
CN115768451A (zh) 2020-06-01 2023-03-07 辉凌公司 ***微生物群组合物
WO2022051610A1 (en) 2020-09-04 2022-03-10 Ferring B.V. Microbiota restoration therapy (mrt) compositions and methods of manufacture
WO2023150544A1 (en) * 2022-02-01 2023-08-10 Seattle Children's Hospital D/B/A Seattle Children's Research Institute Simplified method of preparing cells for patient administration

Family Cites Families (120)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL257275A (sl) 1959-10-26
US3261761A (en) 1962-05-07 1966-07-19 Arthur W Anderson Method of freeze drying bacterial cultures
DE3887353T2 (de) 1987-10-12 1994-05-05 Exomed Australia Pty Ltd Behandlungsverfahren für magen-darm-krankheiten.
AU2900889A (en) 1987-12-24 1989-07-19 Thomas Julius Borody Orthostatic lavage solutions
DE68928665T2 (de) 1988-08-02 1998-11-12 Gastro Services Pty Ltd Behandlung von gastro-intestinalen krankheiten
US5443826A (en) * 1988-08-02 1995-08-22 Borody; Thomas J. Treatment of gastro-intestinal disorders with a fecal composition or a composition of bacteroides and E. Coli
CA1337265C (en) 1988-08-04 1995-10-10 Thomas Julius Borody Oral antibody therapy for patients with lowered immune response and composition therefor
CA2051092C (en) 1990-09-12 2002-07-23 Stephen A. Livesey Method and apparatus for cryopreparation, dry stabilization and rehydration of biological suspensions
US5519014A (en) 1990-10-22 1996-05-21 Borody; Thomas J. Treatment of non-inflammatory and non-infectious bowel disorders
CA2090220C (en) 1990-10-22 2003-07-08 Thomas Julius Borody Treatment of non-inflammatory and non-infectious bowel disorders
US5229374A (en) 1992-01-28 1993-07-20 Burton Albert F Method for treatment of lower gastrointestinal tract disorders
US5599795A (en) 1994-08-19 1997-02-04 Mccann; Michael Method for treatment of idiopathic inflammatory bowel disease (IIBD)
AUPM864894A0 (en) 1994-10-07 1994-11-03 Borody, Thomas Julius Treatment of bowel-dependent neurological disorders
US7048906B2 (en) 1995-05-17 2006-05-23 Cedars-Sinai Medical Center Methods of diagnosing and treating small intestinal bacterial overgrowth (SIBO) and SIBO-related conditions
US6861053B1 (en) 1999-08-11 2005-03-01 Cedars-Sinai Medical Center Methods of diagnosing or treating irritable bowel syndrome and other disorders caused by small intestinal bacterial overgrowth
US5656283A (en) 1995-06-08 1997-08-12 Ortho Pharmaceutical Corporation In-situ lyophilization of vaginal suppository in unit dose applicator and resultant product
ATE310391T1 (de) 1995-09-15 2005-12-15 Dale N Gerding Verfahren und zusammensetzung zur vorbeugung und behandlung von mit clostridium difficile assoziierten erkrankungen
AUPN634595A0 (en) 1995-11-03 1995-11-30 Borody, Thomas Julius Improved method for colonic evacuation
US6103268A (en) 1995-11-03 2000-08-15 Borody; Thomas Julius Administering osmotic colonic evacuant containing a picosulfate
US5925354A (en) 1995-11-30 1999-07-20 Michigan State University Riboflavin mutants as vaccines against Actinobacillus pleuropneumoniae
US5711446A (en) * 1996-01-16 1998-01-27 Sorenson Bioscience, Inc. Cryogenic freezing vial
US5902578A (en) 1996-03-25 1999-05-11 Abbott Laboratories Method and formula for the prevention of diarrhea
US5837238A (en) 1996-06-05 1998-11-17 Biogaia Biologics Ab Treatment of diarrhea
US6096310A (en) 1997-04-15 2000-08-01 Bier; Milan Oral immunotherapy of bacterial overgrowth
AUPO665397A0 (en) 1997-05-07 1997-05-29 Borody, Thomas Julius Novel therapy for constipation
US6969520B2 (en) 1997-10-20 2005-11-29 Acambis Inc. Active immunization against clostridium difficile disease
EP2305303A3 (en) 1997-10-20 2013-11-13 Sanofi Pasteur Biologics Co. Immunization against Clostridium difficile disease
US6428783B1 (en) 1998-03-11 2002-08-06 Medtech Center, Inc. Bank of autochthonous strains of microorganisms and methods of its use for recovery of intestinal microbiocenosis of the men
US6461607B1 (en) 1998-08-24 2002-10-08 Ganeden Biotech, Inc. Probiotic, lactic acid-producing bacteria and uses thereof
AU1093900A (en) 1998-09-21 2000-04-10 21St Century Medicine, Inc. Improved cryoprotectant solutions
ID29150A (id) * 1999-01-15 2001-08-02 Entpr Ireland Cs Penggunaan lactobacillus salivarius
US7430478B2 (en) * 2000-03-01 2008-09-30 Caridian Bct, Inc. Blood processing information system with blood loss equivalency tracking
FR2808689B1 (fr) 2000-05-11 2004-09-03 Agronomique Inst Nat Rech Utilisation de souches acetogenes hydrogenotrophes pour la prevention ou le traitement de troubles digestifs
US20040170617A1 (en) 2000-06-05 2004-09-02 Finegold Sydney M. Method of treating diseases associated with abnormal gastrointestinal flora
US20040062757A1 (en) 2001-06-05 2004-04-01 Finegold Sydney M. Method of testing gastrointestinal diseases associated with species of genus clostridium
US20020013270A1 (en) 2000-06-05 2002-01-31 Bolte Ellen R. Method for treating a mental disorder
CN1444484A (zh) 2000-06-19 2003-09-24 穆科普罗泰科有限公司 用益生菌对粘膜表面的细菌或病毒感染进行治疗或免疫治疗及用于此的组合物
CA2416120A1 (en) 2000-07-17 2002-01-24 Svend Laulund Methods and formulations with probiotic microorganisms and medicaments
AUPQ899700A0 (en) 2000-07-25 2000-08-17 Borody, Thomas Julius Probiotic recolonisation therapy
EP2071332A1 (en) 2000-11-14 2009-06-17 Techlab, Inc. Method for monitoring persons with IBD using total endogeneous lactoferrin as a marker
PL222211B1 (pl) 2001-06-26 2016-07-29 Amgen Fremont Inc Przeciwciało przeciwko OPGL, kompozycja je zawierająca, jego zastosowanie i sposób jego wytwarzania, sposób wykrywania poziomu OPGL, kompozycja obejmująca polinukleotydy i komórka gosodarza
EP1432786B1 (en) 2001-09-06 2009-07-22 Genomic Profiling Systems, Inc. Rapid detection of replicating cells
EP1300472A1 (en) 2001-10-02 2003-04-09 Stichting Top-Instituut Voedselwetenschappen A method for testing the effect of nutrients on gastrointestinal colonisation resistance of humans
GB0124580D0 (en) 2001-10-12 2001-12-05 Univ Reading New composition
US20030154105A1 (en) * 2001-12-10 2003-08-14 Ferguson Martin L. Systems and methods for obtaining data correlated patient samples
US20030161871A1 (en) 2001-12-19 2003-08-28 Geoffrey Hird Solubilized riboflavin
AUPS088702A0 (en) 2002-03-04 2002-03-28 Borody, Thomas Julius Electrolyte purgative
EP1596872B1 (en) 2003-01-24 2011-06-22 Flora Technology Inc. Compositions and methods for restoring bacterial flora
GB0322791D0 (en) 2003-09-30 2003-10-29 Lifeforce Group Plc Blood co-processing for contingent autologous leukocyte transplantation
US20050239706A1 (en) 2003-10-31 2005-10-27 Washington University In St. Louis Modulation of fiaf and the gastrointestinal microbiota as a means to control energy storage in a subject
US20060008511A1 (en) 2004-07-08 2006-01-12 Jhy-Jhu Lin Probiotic products for pet applications
US7935334B2 (en) 2005-07-07 2011-05-03 Imagilin Technologies, LLC Probiotics as alternative medicines against infectious diseases
US7909806B2 (en) 2004-09-23 2011-03-22 Anthrogenesis Corporation Cord blood and placenta collection kit
EP1817432A2 (en) 2004-10-05 2007-08-15 Wyeth a Corporation of the State of Delaware Probe arrays for detecting multiple strains of different species
CA2586998A1 (en) 2004-11-08 2006-05-26 Yale University Structure-based compound design involving riboswitches
US20060210448A1 (en) 2005-03-10 2006-09-21 Naishu Wang Fecal specimen collection, preserving and transport device and method
AU2006224760A1 (en) 2005-03-17 2006-09-21 Synthon B.V. Pharmaceutical tablets of crystalline Type II aripiprazole
US7607776B1 (en) 2005-10-24 2009-10-27 James Waller Lambuth Lewis Digital eye bank for virtual clinic trials
US8313901B2 (en) 2005-12-21 2012-11-20 Yale University Methods and compositions related to the modulation of riboswitches
CA2635038A1 (en) 2005-12-29 2007-07-05 Hill's Pet Nutrition, Inc. Method for modifying gut flora in animals
US20080027353A1 (en) 2006-07-31 2008-01-31 Kliman Harvey J Method of making and using a library of biological information
EP2089076A2 (en) 2006-10-13 2009-08-19 Reliance Life Sciences Pvt., Ltd. Cultured melanocytes on biopolymers
US20100172874A1 (en) 2006-12-18 2010-07-08 The Washington University Gut microbiome as a biomarker and therapeutic target for treating obesity or an obesity related disorder
JP5537420B2 (ja) 2007-05-31 2014-07-02 ユニヴァーシティ オブ ワシントン 標的遺伝子の誘導性変異誘発
EP2030623A1 (en) 2007-08-17 2009-03-04 Nestec S.A. Preventing and/or treating metabolic disorders by modulating the amount of enterobacteria
WO2009042645A2 (en) 2007-09-24 2009-04-02 President And Fellows Of Harvard College The use of mice predisposed to develop ulcerative colitis and colon cancer to develop metabolic profiles associated with same
US20090138354A1 (en) 2007-11-25 2009-05-28 Herbert Zech Methods of Storing and Providing Samples of Cells and Tissue
US20090148540A1 (en) 2007-12-10 2009-06-11 Mi Hope Incorporated Antibacterial composition and method of production
US20110237549A1 (en) 2008-03-27 2011-09-29 Memorial Sloan Kettering Cancer Center Modulators of rna riboswitches
US20110177976A1 (en) 2008-06-30 2011-07-21 The Washington University Methods for promoting weight loss and associated arrays
US20100008850A1 (en) 2008-07-14 2010-01-14 William John Martin Method of generating hydrogen in drinking water using an enerceutical product added to magnesium in a hydrogen permeable but solute impermeable container
CN104247718A (zh) 2008-07-17 2014-12-31 生物工厂公司 利用绿木霉物种与根际活性的哈茨木霉物种的组合来控制植物疾病与增强植物生长
US20120077781A1 (en) 2008-08-11 2012-03-29 Robert Gadwood Flavin derivatives
KR101795643B1 (ko) 2009-05-01 2017-11-09 훼링 비.브이. 전립선암 치료용 조성물
GB0916335D0 (en) 2009-09-17 2009-10-28 Martin W J Medicaments
EP2480255B1 (en) 2009-09-23 2017-11-22 Thomas Julius Borody Therapy for chronic enteric infections
DE112010004110T8 (de) 2009-10-22 2012-12-06 Thomas Julius Borody Neue parasitentherapie
PL2493471T3 (pl) 2009-10-26 2020-10-19 Borody Nowa skojarzona terapia jelitowa
PT3564357T (pt) 2010-02-01 2022-06-14 Rebiotix Inc Bacterioterapia para colite por clostridium difficile
US8853269B2 (en) 2010-02-04 2014-10-07 Copperhead Chemical Company Inc. Composition and method for treating infections and promoting intestinal health
FI20105478A0 (fi) 2010-04-30 2010-04-30 Valtion Teknillinen Menetelmä tyypin 1 diabeteksen diagnosoimiseksi ja menetelmiä ja koostumuksia tyypin 1 diabeteksen puhkeamisen estämiseksi
US9707207B2 (en) 2010-05-26 2017-07-18 The United States Of America As Represented By The Department Of Veterans Affairs Method for diagnosing, preventing, and treating neurological diseases
WO2011151941A1 (ja) 2010-06-04 2011-12-08 国立大学法人東京大学 制御性t細胞の増殖または集積を誘導する作用を有する組成物
FI20105825A (fi) 2010-07-26 2012-01-27 Suomen Punainen Risti Veripalvelu Veriryhmästatuksen käyttö III
WO2012013861A2 (en) 2010-07-26 2012-02-02 Suomen Punainen Risti Veripalvelu Use of blood group status iii
WO2012016287A2 (en) 2010-08-04 2012-02-09 Borody Thomas J Compositions for fecal floral transplantation and methods for making and using them and devices for deuvering them
WO2012024638A2 (en) 2010-08-20 2012-02-23 New York University Compositions and methods for treating obesity and related disorders by characterizing and restoring mammalian bacterial microbiota
WO2012033814A2 (en) 2010-09-10 2012-03-15 Viropharma Incorporated Environmental clostridial bacteriotherapy and related formulations and methods of manufacture and use
WO2014152484A1 (en) 2013-03-14 2014-09-25 Regents Of The University Of Minnesota Freeze dried fecal microbiota for use in fecal microbial transplantation
WO2012122522A2 (en) 2011-03-09 2012-09-13 Washington University Cultured collection of gut microbial community
EP3610881A1 (en) 2011-03-09 2020-02-19 Regents Of The University Of Minnesota Compositions and methods for transplantation of colon microbiota
WO2012142605A1 (en) 2011-04-15 2012-10-18 Samaritan Health Services Rapid recolonization deployment agent
US20120276060A1 (en) 2011-04-29 2012-11-01 Techlab, Inc. Fecal lactoferrin as a biomarker for determining disease severity and for treating infection in patients with clostridium difficile disease
US20130022575A1 (en) 2011-07-19 2013-01-24 Microbial Rx Systems and methods of replacing intestinal flora
EP2748330A1 (en) 2011-08-26 2014-07-02 Microbiota Diagnostics, LLC Methods for diagnosing and treating cardiac defects
AU2012322979B2 (en) 2011-10-11 2017-02-02 Achim Biotherapeutics Ab Composition comprising anaerobically cultivated human intestinal microbiota
US9176026B2 (en) 2011-12-15 2015-11-03 Pureflora, Inc. Device for the collection, refinement, and administration of gastrointestinal microflora
US9173910B2 (en) 2012-02-29 2015-11-03 The General Hospital Corporation Compositions of microbiota and methods related thereto
EP2636684A1 (en) 2012-03-09 2013-09-11 CSL Behring AG Prevention of infection
WO2013163582A1 (en) 2012-04-27 2013-10-31 Cedars-Sinai Medical Center Fungal mycobiome as probiotics, diagnostics and therapeutics
EP2850202B1 (en) 2012-05-18 2020-03-11 Genome Research Limited Methods and groups
US20140112985A1 (en) 2012-10-22 2014-04-24 Polonez Therapeutics Llc Method of prevention and treatment of clostridium difficile infection
WO2014100826A1 (en) 2012-12-23 2014-06-26 Illuminate Consulting, Llc. Method and apparatus for thermally protecting and/or transporting temperature sensitive products
EP3584308A3 (en) 2013-02-04 2020-03-04 Seres Therapeutics, Inc. Compositions and methods
US9511100B2 (en) 2013-06-05 2016-12-06 Rebiotix, Inc. Microbiota restoration therapy (MRT), compositions and methods of manufacture
US9511099B2 (en) 2013-06-05 2016-12-06 Rebiotix, Inc. Microbiota restoration therapy (MRT), compositions and methods of manufacture
PL3003330T4 (pl) 2013-06-05 2019-03-29 Rebiotix, Inc. Terapia przywracająca mikrobiota (MRT), kompozycje i sposoby wytwarzania
US9694039B2 (en) 2013-06-05 2017-07-04 Rebiotix, Inc. Microbiota restoration therapy (MRT), compositions and methods of manufacture
US10383901B2 (en) 2013-06-05 2019-08-20 Rebiotix, Inc. Microbiota restoration therapy (MRT), compositions and methods of manufacture
US9782445B2 (en) 2013-06-05 2017-10-10 Rebiotix, Inc. Microbiota restoration therapy (MRT), compositions and methods of manufacture
EP3294307A4 (en) 2015-05-14 2019-01-23 Crestovo Holdings Llc COMPOSITIONS FOR TRANSPLANTATION OF FECAL FLORA AND METHODS OF PREPARATION AND USE THEREOF, AND DEVICES FOR THEIR ADMINISTRATION
JP6856968B2 (ja) 2015-05-22 2021-04-14 アリゾナ ボード オブ リージェンツ オン ビハーフ オブ アリゾナ ステート ユニバーシティ 自閉症スペクトラム障害および関連する症候を治療するための方法
CA2987129A1 (en) 2015-06-01 2016-12-08 The University Of Chicago Treatment of cancer by manipulation of commensal microflora
US10799539B2 (en) 2015-06-09 2020-10-13 Rebiotix, Inc. Microbiota restoration therapy (MRT) compositions and methods of manufacture
US10828340B2 (en) 2015-06-09 2020-11-10 Rebiotix, Inc. Microbiota restoration therapy (MRT) compositions and methods of manufacture
US10905726B2 (en) 2015-06-09 2021-02-02 Rebiotix, Inc. Microbiota restoration therapy (MRT) compositions and methods of manufacture
ES2889902T3 (es) 2015-06-09 2022-01-14 Rebiotix Inc Métodos de fabricación de composiciones para terapia de restauración de la microbiota (TRM)
US10173160B2 (en) 2015-10-09 2019-01-08 Heinzen, Llc Effluent removal system and method of use
ITUB20169847A1 (it) 2016-01-05 2017-07-05 Wellmicro S R L Metodo per valutare lo stato di salute di un individuo
US20180000872A1 (en) 2016-07-01 2018-01-04 Regents Of The University Of Minnesota Compositions and methods for c. difficile treatment

Also Published As

Publication number Publication date
US20140086877A1 (en) 2014-03-27
EP3181684A1 (en) 2017-06-21
RS63299B1 (sr) 2022-07-29
HUE059169T2 (hu) 2022-10-28
US20240122995A1 (en) 2024-04-18
US9463208B2 (en) 2016-10-11
WO2011094027A1 (en) 2011-08-04
CA2788558C (en) 2015-11-24
ES2916399T3 (es) 2022-06-30
AU2011209940B2 (en) 2015-08-20
AU2011209940A2 (en) 2012-08-30
AU2011209940A1 (en) 2012-08-23
EP2531589A1 (en) 2012-12-12
HRP20220751T1 (hr) 2022-09-02
EP3564357B1 (en) 2022-04-06
CA2788558A1 (en) 2011-08-04
US20170266241A1 (en) 2017-09-21
PT3564357T (pt) 2022-06-14
EP4032586A1 (en) 2022-07-27
US20230076826A1 (en) 2023-03-09
US11944654B2 (en) 2024-04-02
US20160367607A1 (en) 2016-12-22
US9629881B2 (en) 2017-04-25
US20180243351A1 (en) 2018-08-30
DK3564357T3 (da) 2022-06-20
EP2531589B1 (en) 2017-04-05
EP3181684B1 (en) 2019-05-29
LT3564357T (lt) 2022-07-11
ES2730828T3 (es) 2019-11-12
EP3564357A1 (en) 2019-11-06
US11446337B2 (en) 2022-09-20
PL3564357T3 (pl) 2022-08-08
EP2531589A4 (en) 2014-02-19
ES2623127T3 (es) 2017-07-10
US20130045274A1 (en) 2013-02-21

Similar Documents

Publication Publication Date Title
LT3564357T (lt) Bakterioterapija, skirta clostridium difficile sukeltam kolitui
GB2498008B (en) State transition
GB2506331B (en) Seal member
HK1199886A1 (en) Clostridium difficile antibodies
DK2737264T3 (en) Startlogik til kølesystem
DK3327110T3 (en) Kassette til sterilitetstest
GB201016742D0 (en) Clostridium difficile antigens
HK1189301A1 (zh) 開關裝置
ZA201409097B (en) Solid state bioreactor adapted for automation
HK1202805A1 (en) Clostridium difficile antigens
GB2495092B (en) Sealing arrangement
IL232957A0 (en) A composition based on clostridium difficile toxin
HK1216999A1 (zh) 針對艱難梭菌的抗體
IL237172A0 (en) פוליפפטידים של clostridium difficile כתרכיבים
EP2548959A4 (en) FLORIGENIC ACTIVATOR COMPLEX
GB201105625D0 (en) Seal
ZA201403228B (en) Heterocyclypyri(mi)dinylpyrazole
EP2765177A4 (en) GASIFICATION SYSTEM
GB201120213D0 (en) B0-U component seal
ZA201402298B (en) Heterocyclylpyri (mi)dinylpyrazole as fungicidals
EP2780351A4 (en) LIPOTHEICHOIC ACID OF DIFFICULT CLOSTRIDIUM AND USES THEREOF
GB2500854B (en) Biosurface engineering
PL2495467T3 (pl) System uszczelniający
GB201010960D0 (en) Complex
HK1195874A1 (zh) 艱難梭狀芽孢杆菌增殖抑制劑