SI2964622T1 - Nova sol abeksinostata, z njo povezana kristalna oblika, nje postopek za pripravo in farmacevski sestavki, ki jo vsebujejo - Google Patents

Nova sol abeksinostata, z njo povezana kristalna oblika, nje postopek za pripravo in farmacevski sestavki, ki jo vsebujejo

Info

Publication number: SI2964622T1
Authority: SI; Slovenia
Prior art keywords: abexinostat; salt; novel; preparation; pharmaceutical compositions
Prior art date: 2013-03-04

Application number

SI201430278T

Other languages

English (en)

Inventor

Anne Pimont-Garro

Philippe Letellier

Original Assignee

Pharmacyclics Llc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2013-03-04

Filing date

2014-03-03

Publication date

2017-10-30

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48521256&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI2964622(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2014-03-03 Application filed by Pharmacyclics Llc filed Critical Pharmacyclics Llc

2017-10-30 Publication of SI2964622T1 publication Critical patent/SI2964622T1/sl

Links

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D307/84—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D307/85—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/01—Sulfonic acids
- C07C309/28—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C309/29—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton of non-condensed six-membered aromatic rings
- C07C309/30—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton of non-condensed six-membered aromatic rings of six-membered aromatic rings substituted by alkyl groups

SI201430278T 2013-03-04 2014-03-03 Nova sol abeksinostata, z njo povezana kristalna oblika, nje postopek za pripravo in farmacevski sestavki, ki jo vsebujejo SI2964622T1 (sl)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US201361772191P	2013-03-04	2013-03-04
FR1351898A FR3002733B1 (fr)	2013-03-04	2013-03-04	Nouveau sel de l'abexinostat, forme cristalline associee,leur procede de preparation et les compositions pharmaceutiques qui les contiennent
EP14711833.5A EP2964622B1 (fr)	2013-03-04	2014-03-03	Nouveau sel de l'abexinostat, forme cristalline associee, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
PCT/FR2014/050455 WO2014135776A1 (fr)	2013-03-04	2014-03-03	Nouveau sel de l'abexinostat, forme cristalline associee, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number	Publication Date
SI2964622T1 true SI2964622T1 (sl)	2017-10-30

Family

ID=48521256

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SI201430278T SI2964622T1 (sl)	2013-03-04	2014-03-03	Nova sol abeksinostata, z njo povezana kristalna oblika, nje postopek za pripravo in farmacevski sestavki, ki jo vsebujejo

Country Status (39)

Country	Link
US (3)	US9115108B2 (sl)
EP (2)	EP3252044A1 (sl)
JP (2)	JP6449177B2 (sl)
CN (2)	CN109734690B (sl)
AR (1)	AR094935A1 (sl)
AU (2)	AU2014224456B2 (sl)
BR (1)	BR112015021443A2 (sl)
CA (1)	CA2903369C (sl)
CL (1)	CL2015002488A1 (sl)
CR (1)	CR20150456A (sl)
CY (1)	CY1119147T1 (sl)
DK (1)	DK2964622T3 (sl)
DO (1)	DOP2015000215A (sl)
EA (2)	EA039113B1 (sl)
ES (1)	ES2632471T3 (sl)
FR (1)	FR3002733B1 (sl)
GE (1)	GEP201706760B (sl)
HK (1)	HK1220965A1 (sl)
HR (1)	HRP20171041T1 (sl)
HU (1)	HUE035299T2 (sl)
IL (1)	IL241038B (sl)
JO (1)	JO3402B1 (sl)
LT (1)	LT2964622T (sl)
MA (1)	MA38423B1 (sl)
ME (1)	ME02814B (sl)
MX (1)	MX355436B (sl)
MY (1)	MY192027A (sl)
NI (1)	NI201500122A (sl)
PE (1)	PE20151591A1 (sl)
PL (1)	PL2964622T3 (sl)
PT (1)	PT2964622T (sl)
RS (1)	RS56224B1 (sl)
SG (1)	SG11201506952YA (sl)
SI (1)	SI2964622T1 (sl)
TN (1)	TN2015000367A1 (sl)
TW (1)	TWI506023B (sl)
UA (1)	UA118550C2 (sl)
UY (1)	UY35356A (sl)
WO (1)	WO2014135776A1 (sl)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN107898791A (zh)	2010-06-03	2018-04-13	药品循环有限责任公司	布鲁顿酪氨酸激酶(btk)抑制剂的应用
KR20150032340A (ko)	2012-07-24	2015-03-25	파마시클릭스, 인코포레이티드	브루톤 티로신 키나제(btk)의 억제제에 대한 내성과 관련된 돌연변이
US20150291554A1 (en)	2012-11-02	2015-10-15	Pfizer Inc.	Bruton's Tyrosine Kinase Inhibitors
FR3002733B1 (fr)	2013-03-04	2015-08-14	Servier Lab	Nouveau sel de l'abexinostat, forme cristalline associee,leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US9885086B2 (en)	2014-03-20	2018-02-06	Pharmacyclics Llc	Phospholipase C gamma 2 and resistance associated mutations
FR3025197B1 (fr) *	2014-09-03	2019-09-06	Pharmacyclics, Inc.	Nouveau sel de 3-[(dimethylamino)methyl]-n-{2-[4-(hydroxycarbamoyl)phenoxy]ethyl}-1-benzofurane-2-carboxamide, formes cristallines associees, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR3025196B1 (fr) *	2014-09-03	2019-09-06	Pharmacyclics, Inc.	Nouveaux sels de 3-[(dimethylamino)methyl]-n-{2-[4-(hydroxycarbamoyl)phenoxy]ethyl}-1-benzofurane-2-carboxamide, formes cristallines associees, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
KR20170043648A (ko) *	2014-09-03	2017-04-21	파마싸이클릭스 엘엘씨	3-[(디메틸아미노)메틸]-n-｛2-[4-(히드록시카르바모일)페녹시]에틸｝-1-벤조푸란-2-카르복사미드의 신규 염, 관련 결정형, 이의 제조 방법 및 이를 함유하는 약학 조성물
WO2017011314A1 (en) *	2015-07-10	2017-01-19	Paharmacyclics Llc	Btk and hdac combinations
WO2022261401A1 (en)	2021-06-10	2022-12-15	Teva Pharmaceuticals International Gmbh	Solid state forms of abexinostat and process for preparation thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3038004A (en) *	1958-04-18	1962-06-05	Burroughs Wellcome Co	Quaternary ammonium compounds
GB0020721D0 (en) *	2000-08-22	2000-10-11	Merck Sharp & Dohme	Therapeutic agents
EP1611088B1 (en) *	2003-04-07	2009-06-17	Pharmacyclics, Inc.	Hydroxamates as therapeutic agents
US20090270497A1 (en) *	2008-04-24	2009-10-29	Pharmacyclics, Inc.	Treatment of Non-Localized Inflammation with pan-HDAC Inhibitors
US8603521B2 (en) *	2009-04-17	2013-12-10	Pharmacyclics, Inc.	Formulations of histone deacetylase inhibitor and uses thereof
CA2775229C (en) *	2009-09-24	2014-07-29	Ranbaxy Laboratories Limited	Process for the preparation of sorafenib tosylate
WO2013039956A2 (en) *	2011-09-14	2013-03-21	The Trustees Of Columbia University In The City Of New York	Compositions and methods for treating mood disorders
FR3002733B1 (fr)	2013-03-04	2015-08-14	Servier Lab	Nouveau sel de l'abexinostat, forme cristalline associee,leur procede de preparation et les compositions pharmaceutiques qui les contiennent

2013
- 2013-03-04 FR FR1351898A patent/FR3002733B1/fr active Active
2014
- 2014-02-18 JO JOP/2014/0040A patent/JO3402B1/ar active
- 2014-02-27 UY UY0001035356A patent/UY35356A/es not_active Application Discontinuation
- 2014-02-28 AR ARP140100648A patent/AR094935A1/es unknown
- 2014-03-03 MX MX2015011566A patent/MX355436B/es active IP Right Grant
- 2014-03-03 CN CN201811248983.5A patent/CN109734690B/zh active Active
- 2014-03-03 ME MEP-2017-139A patent/ME02814B/me unknown
- 2014-03-03 GE GEAP201413950A patent/GEP201706760B/en unknown
- 2014-03-03 EA EA201891023A patent/EA039113B1/ru unknown
- 2014-03-03 SG SG11201506952YA patent/SG11201506952YA/en unknown
- 2014-03-03 MY MYPI2015002172A patent/MY192027A/en unknown
- 2014-03-03 MA MA38423A patent/MA38423B1/fr unknown
- 2014-03-03 SI SI201430278T patent/SI2964622T1/sl unknown
- 2014-03-03 LT LTEP14711833.5T patent/LT2964622T/lt unknown
- 2014-03-03 CA CA2903369A patent/CA2903369C/en active Active
- 2014-03-03 PE PE2015001875A patent/PE20151591A1/es unknown
- 2014-03-03 HU HUE14711833A patent/HUE035299T2/en unknown
- 2014-03-03 EP EP17166690.2A patent/EP3252044A1/fr not_active Withdrawn
- 2014-03-03 UA UAA201508558A patent/UA118550C2/uk unknown
- 2014-03-03 EP EP14711833.5A patent/EP2964622B1/fr active Active
- 2014-03-03 US US14/195,186 patent/US9115108B2/en active Active
- 2014-03-03 TW TW103107081A patent/TWI506023B/zh active
- 2014-03-03 WO PCT/FR2014/050455 patent/WO2014135776A1/fr active Application Filing
- 2014-03-03 DK DK14711833.5T patent/DK2964622T3/en active
- 2014-03-03 PL PL14711833T patent/PL2964622T3/pl unknown
- 2014-03-03 RS RS20170687A patent/RS56224B1/sr unknown
- 2014-03-03 AU AU2014224456A patent/AU2014224456B2/en active Active
- 2014-03-03 BR BR112015021443A patent/BR112015021443A2/pt not_active IP Right Cessation
- 2014-03-03 JP JP2015560740A patent/JP6449177B2/ja active Active
- 2014-03-03 CN CN201480012148.5A patent/CN105263917B/zh active Active
- 2014-03-03 PT PT147118335T patent/PT2964622T/pt unknown
- 2014-03-03 ES ES14711833.5T patent/ES2632471T3/es active Active
- 2014-03-03 EA EA201591530A patent/EA030689B1/ru unknown
2015
- 2015-07-13 US US14/798,412 patent/US20150315167A1/en not_active Abandoned
- 2015-08-26 TN TN2015000367A patent/TN2015000367A1/fr unknown
- 2015-09-02 IL IL241038A patent/IL241038B/en active IP Right Grant
- 2015-09-02 CR CR20150456A patent/CR20150456A/es unknown
- 2015-09-04 CL CL2015002488A patent/CL2015002488A1/es unknown
- 2015-09-04 DO DO2015000215A patent/DOP2015000215A/es unknown
- 2015-09-04 NI NI201500122A patent/NI201500122A/es unknown
2016
- 2016-06-28 HK HK16107535.9A patent/HK1220965A1/zh unknown
2017
- 2017-01-12 US US15/405,021 patent/US10150748B2/en active Active
- 2017-07-06 CY CY20171100723T patent/CY1119147T1/el unknown
- 2017-07-07 HR HRP20171041TT patent/HRP20171041T1/hr unknown
2018
- 2018-04-26 AU AU2018202881A patent/AU2018202881B2/en active Active
- 2018-12-05 JP JP2018228486A patent/JP6720280B2/ja active Active

Also Published As

Publication number	Publication date
CL2015002488A1 (es)	2016-03-11
AU2014224456B2 (en)	2018-01-25
ES2632471T3 (es)	2017-09-13
AU2018202881A1 (en)	2018-05-17
IL241038A0 (en)	2015-11-30
US20140249215A1 (en)	2014-09-04
JO3402B1 (ar)	2019-10-20
CA2903369A1 (en)	2014-09-12
LT2964622T (lt)	2017-08-10
EA201891023A1 (ru)	2019-03-29
ME02814B (me)	2018-01-20
AU2014224456A8 (en)	2015-10-22
US20150315167A1 (en)	2015-11-05
UY35356A (es)	2014-09-30
PL2964622T3 (pl)	2017-10-31
CA2903369C (en)	2021-06-08
CN105263917A (zh)	2016-01-20
CY1119147T1 (el)	2018-02-14
US10150748B2 (en)	2018-12-11
NI201500122A (es)	2018-10-18
EA030689B1 (ru)	2018-09-28
AR094935A1 (es)	2015-09-09
DK2964622T3 (en)	2017-07-31
HUE035299T2 (en)	2018-05-02
MX2015011566A (es)	2016-06-24
EA201591530A1 (ru)	2016-01-29
EA039113B1 (ru)	2021-12-06
PT2964622T (pt)	2017-07-13
PE20151591A1 (es)	2015-11-06
RS56224B1 (sr)	2017-11-30
TW201434822A (zh)	2014-09-16
US9115108B2 (en)	2015-08-25
JP6720280B2 (ja)	2020-07-08
EP2964622B1 (fr)	2017-04-19
MY192027A (en)	2022-07-23
AU2014224456A1 (en)	2015-10-08
NZ712380A (en)	2020-10-30
JP6449177B2 (ja)	2019-01-09
CR20150456A (es)	2015-10-21
MX355436B (es)	2018-04-18
SG11201506952YA (en)	2015-10-29
JP2019069955A (ja)	2019-05-09
AU2018202881B2 (en)	2020-02-27
UA118550C2 (uk)	2019-02-11
HRP20171041T1 (hr)	2017-10-06
GEP201706760B (en)	2017-10-25
CN105263917B (zh)	2018-11-20
EP3252044A1 (fr)	2017-12-06
CN109734690A (zh)	2019-05-10
IL241038B (en)	2019-09-26
TN2015000367A1 (fr)	2017-01-03
FR3002733B1 (fr)	2015-08-14
MA38423B1 (fr)	2017-10-31
JP2016510735A (ja)	2016-04-11
BR112015021443A2 (pt)	2017-07-18
EP2964622A1 (fr)	2016-01-13
HK1220965A1 (zh)	2017-05-19
FR3002733A1 (fr)	2014-09-05
WO2014135776A1 (fr)	2014-09-12
DOP2015000215A (es)	2015-09-30
TWI506023B (zh)	2015-11-01
US20170313671A1 (en)	2017-11-02
MA38423A1 (fr)	2017-02-28
CN109734690B (zh)	2023-08-11

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