SI2699327T1 - Postopek čiščenja mikafungina - Google Patents

Postopek čiščenja mikafungina

Info

Publication number
SI2699327T1
SI2699327T1 SI201230299T SI201230299T SI2699327T1 SI 2699327 T1 SI2699327 T1 SI 2699327T1 SI 201230299 T SI201230299 T SI 201230299T SI 201230299 T SI201230299 T SI 201230299T SI 2699327 T1 SI2699327 T1 SI 2699327T1
Authority
SI
Slovenia
Prior art keywords
micafungin
purification
Prior art date
Application number
SI201230299T
Other languages
English (en)
Inventor
Lene Aassveen
Eli Karin Dale
Espen Fridtjof Hansen
Kjersti Meldahl Eide
Original Assignee
Xelia Pharmaceuticals Aps
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xelia Pharmaceuticals Aps filed Critical Xelia Pharmaceuticals Aps
Publication of SI2699327T1 publication Critical patent/SI2699327T1/sl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/26Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/32Bonded phase chromatography
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/26Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/32Bonded phase chromatography
    • B01D15/325Reversed phase
    • B01D15/327Reversed phase with hydrophobic interaction
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Materials For Photolithography (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Silicates, Zeolites, And Molecular Sieves (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
SI201230299T 2011-04-20 2012-04-13 Postopek čiščenja mikafungina SI2699327T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161477190P 2011-04-20 2011-04-20
EP12713998.8A EP2699327B1 (en) 2011-04-20 2012-04-13 Method for purification of micafungin
PCT/EP2012/056768 WO2012143293A1 (en) 2011-04-20 2012-04-13 Method for purification of micafungin

Publications (1)

Publication Number Publication Date
SI2699327T1 true SI2699327T1 (sl) 2015-11-30

Family

ID=45953151

Family Applications (1)

Application Number Title Priority Date Filing Date
SI201230299T SI2699327T1 (sl) 2011-04-20 2012-04-13 Postopek čiščenja mikafungina

Country Status (18)

Country Link
US (1) US9132163B2 (sl)
EP (2) EP2918324A1 (sl)
JP (1) JP5992507B2 (sl)
KR (1) KR101944512B1 (sl)
CN (1) CN103533995B (sl)
AU (1) AU2012244435B2 (sl)
BR (1) BR112013026420A2 (sl)
CA (1) CA2832145C (sl)
DK (1) DK2699327T3 (sl)
ES (1) ES2547827T3 (sl)
HR (1) HRP20151033T1 (sl)
HU (1) HUE027806T2 (sl)
IL (1) IL228913A (sl)
PL (1) PL2699327T3 (sl)
RS (1) RS54240B1 (sl)
RU (1) RU2583262C2 (sl)
SI (1) SI2699327T1 (sl)
WO (1) WO2012143293A1 (sl)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI2699327T1 (sl) * 2011-04-20 2015-11-30 Xelia Pharmaceuticals Aps Postopek čiščenja mikafungina
CN102775476B (zh) * 2011-05-12 2015-01-07 上海天伟生物制药有限公司 一种米卡芬净钠盐的制备方法
CN105254721B (zh) * 2014-05-13 2021-05-18 江苏豪森药业集团有限公司 米卡芬净的纯化转盐方法
WO2015180678A1 (zh) * 2014-05-29 2015-12-03 上海天伟生物制药有限公司 环肽类化合物的晶体及其制备方法和用途
JP6491325B2 (ja) * 2014-05-29 2019-03-27 シャンハイ テックウェル バイオファーマシューティカル カンパニー リミテッドShanghai Techwell Biopharmaceutical Co.,Ltd シクロペプチド系化合物の溶媒和物およびその製造方法と使用
CN105693824A (zh) * 2015-08-27 2016-06-22 博瑞生物医药(苏州)股份有限公司 一种降低米卡芬净钠原料药溶剂残留量的方法
KR101880179B1 (ko) * 2016-11-03 2018-07-20 한국생명공학연구원 미카펀진(micafungin) 또는 이의 약학적으로 허용 가능한 염을 유효성분으로 함유하는 항바이러스용 약학적 조성물
CN108250274A (zh) * 2016-12-28 2018-07-06 浙江华谱新创科技有限公司 米卡芬净高效分离纯化方法
EP3485873A1 (en) * 2017-11-17 2019-05-22 Cadila Healthcare Limited Stable pharmaceutical injectable compositions of micafungin
CN108752430B (zh) * 2018-05-31 2022-02-18 杭州中美华东制药有限公司 米卡芬净钠新晶型及其制备方法
CN111909244A (zh) * 2020-08-14 2020-11-10 卓和药业集团有限公司 一种高纯度米卡芬净前体fr901379的制备方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR901379A (fr) 1943-09-10 1945-07-25 Télégraphie par variations de fréquence
US5202309A (en) * 1989-06-30 1993-04-13 Merck & Co., Inc. Antibiotic cyclopeptide fermentation product
IE990233A1 (en) 1990-06-18 2000-11-15 Fujisawa Pharmaceutical Co New Polypeptide Compound and a Process for Preparation thereof
US6107458A (en) 1994-10-07 2000-08-22 Fujisawa Pharmaceutical Co., Ltd. Cyclic hexapeptides having antibiotic activity
US6227164B1 (en) 1998-04-24 2001-05-08 Cooper Automotive Products, Inc. Insulator shield for spark plug
JP2003511345A (ja) * 1998-12-09 2003-03-25 イーライ リリー アンド カンパニー Echinocandinシクロペプチド化合物の精製
JP2005053782A (ja) * 2001-08-31 2005-03-03 Fujisawa Pharmaceut Co Ltd 環状リポペプチド化合物の新規結晶
WO2004014879A1 (en) 2002-08-08 2004-02-19 Fujisawa Pharmaceutical Co., Ltd. New process
TW200826957A (en) * 2006-10-16 2008-07-01 Teva Gyogyszergyar Zartkoruen Mukodo Reszvenytarsasag Purification processes for echinocandin-type compounds
US9394340B2 (en) 2009-03-24 2016-07-19 Cadila Healthcare Limited Purification process for lipopeptides
CN103180336B (zh) 2010-09-28 2016-06-15 中化帝斯曼制药有限公司荷兰公司 用于分离环六肽的方法
CA2813330A1 (en) 2010-09-29 2012-04-05 Shanghai Techwell Biopharmaceutical Co., Ltd. Process for purifying cyclolipopeptide compounds or the salts thereof
SI2699327T1 (sl) * 2011-04-20 2015-11-30 Xelia Pharmaceuticals Aps Postopek čiščenja mikafungina

Also Published As

Publication number Publication date
WO2012143293A1 (en) 2012-10-26
IL228913A (en) 2017-03-30
JP5992507B2 (ja) 2016-09-14
IL228913A0 (en) 2013-12-31
AU2012244435A1 (en) 2013-10-24
EP2699327A1 (en) 2014-02-26
RS54240B1 (en) 2015-12-31
ES2547827T8 (es) 2015-10-21
HRP20151033T1 (hr) 2015-11-06
CA2832145A1 (en) 2012-10-26
HUE027806T2 (en) 2016-11-28
RU2583262C2 (ru) 2016-05-10
CA2832145C (en) 2020-10-20
AU2012244435B2 (en) 2017-06-15
EP2918324A1 (en) 2015-09-16
ES2547827T3 (es) 2015-10-08
US9132163B2 (en) 2015-09-15
EP2699327B1 (en) 2015-07-01
CN103533995A (zh) 2014-01-22
BR112013026420A2 (pt) 2020-11-03
KR20140029453A (ko) 2014-03-10
CN103533995B (zh) 2016-03-02
US20140371423A1 (en) 2014-12-18
RU2013150600A (ru) 2015-05-27
PL2699327T3 (pl) 2015-12-31
DK2699327T3 (en) 2015-10-05
JP2014511886A (ja) 2014-05-19
KR101944512B1 (ko) 2019-01-31

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