SI2121553T1 - Postopek za pripravo terapevtsko uporabnih trifenilbutenskih derivatov - Google Patents

Postopek za pripravo terapevtsko uporabnih trifenilbutenskih derivatov

Info

Publication number
SI2121553T1
SI2121553T1 SI200830708T SI200830708T SI2121553T1 SI 2121553 T1 SI2121553 T1 SI 2121553T1 SI 200830708 T SI200830708 T SI 200830708T SI 200830708 T SI200830708 T SI 200830708T SI 2121553 T1 SI2121553 T1 SI 2121553T1
Authority
SI
Slovenia
Prior art keywords
preparation
therapeutically valuable
derivatives
triphenylbutene derivatives
valuable triphenylbutene
Prior art date
Application number
SI200830708T
Other languages
English (en)
Inventor
Marja Sodervall
Maire Eloranta
Arja Kalapudas
Original Assignee
Hormos Medical Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hormos Medical Ltd filed Critical Hormos Medical Ltd
Publication of SI2121553T1 publication Critical patent/SI2121553T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/01—Preparation of ethers
    • C07C41/18—Preparation of ethers by reactions not forming ether-oxygen bonds
    • C07C41/30—Preparation of ethers by reactions not forming ether-oxygen bonds by increasing the number of carbon atoms, e.g. by oligomerisation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/01—Preparation of ethers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/01—Preparation of ethers
    • C07C41/18—Preparation of ethers by reactions not forming ether-oxygen bonds
    • C07C41/26—Preparation of ethers by reactions not forming ether-oxygen bonds by introduction of hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/31—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by introduction of functional groups containing oxygen only in singly bound form
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SI200830708T 2007-02-14 2008-02-13 Postopek za pripravo terapevtsko uporabnih trifenilbutenskih derivatov SI2121553T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US88983807P 2007-02-14 2007-02-14
PCT/FI2008/050057 WO2008099059A1 (en) 2007-02-14 2008-02-13 Method for the preparation of therapeutically valuable triphenylbutene derivatives
EP08718510A EP2121553B1 (en) 2007-02-14 2008-02-13 Method for the preparation of therapeutically valuable triphenylbutene derivatives

Publications (1)

Publication Number Publication Date
SI2121553T1 true SI2121553T1 (sl) 2012-11-30

Family

ID=39271403

Family Applications (2)

Application Number Title Priority Date Filing Date
SI200830708T SI2121553T1 (sl) 2007-02-14 2008-02-13 Postopek za pripravo terapevtsko uporabnih trifenilbutenskih derivatov
SI200831331T SI2518039T1 (sl) 2007-02-14 2008-02-13 Postopek za pripravo terapevtsko dragocenih derivatov trifenilbutena

Family Applications After (1)

Application Number Title Priority Date Filing Date
SI200831331T SI2518039T1 (sl) 2007-02-14 2008-02-13 Postopek za pripravo terapevtsko dragocenih derivatov trifenilbutena

Country Status (19)

Country Link
US (2) US7812197B2 (sl)
EP (3) EP2518039B8 (sl)
JP (1) JP5363344B2 (sl)
KR (1) KR101510646B1 (sl)
CN (1) CN101636372B (sl)
AU (1) AU2008214530B2 (sl)
BR (2) BRPI0807675B1 (sl)
CA (1) CA2677861C (sl)
CY (1) CY1113184T1 (sl)
DK (1) DK2121553T3 (sl)
ES (3) ES2389961T3 (sl)
HK (2) HK1139379A1 (sl)
HR (1) HRP20141107T1 (sl)
MX (1) MX2009008660A (sl)
PL (1) PL2121553T3 (sl)
PT (1) PT2121553E (sl)
RU (1) RU2465261C2 (sl)
SI (2) SI2121553T1 (sl)
WO (1) WO2008099059A1 (sl)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI2121553T1 (sl) * 2007-02-14 2012-11-30 Hormos Medical Ltd Postopek za pripravo terapevtsko uporabnih trifenilbutenskih derivatov
EP2526080B1 (en) * 2010-01-19 2014-03-26 Cambrex Karlskoga AB New processes for producing benzophenone derivatives
KR101308258B1 (ko) * 2010-10-15 2013-09-13 씨제이제일제당 (주) 엔독시펜의 신규한 제조 방법
US9321712B2 (en) 2012-10-19 2016-04-26 Fermion Oy Process for the preparation of ospemifene
WO2014060640A1 (en) 2012-10-19 2014-04-24 Fermion Oy A process for the preparation of ospemifene
CN103739456A (zh) * 2013-12-03 2014-04-23 镇江圣安医药有限公司 2-（对-（（z-4-氯-1,2-二苯基-1-丁烯基）苯氧基）乙醇的新型衍生物及其应用
CN104788300B (zh) * 2014-01-22 2017-01-11 南京华威医药科技开发有限公司 欧司哌米芬多晶型
CN104230723B (zh) * 2014-08-21 2016-08-24 凯莱英医药集团（天津）股份有限公司 托瑞米芬的合成方法
WO2016043189A1 (ja) * 2014-09-16 2016-03-24 塩野義製薬株式会社 トリフェニルブテン誘導体の製造方法
US9975832B2 (en) * 2014-12-29 2018-05-22 Olon S.P.A. Process for the preparation of ospemifene and fispemifene
US10138190B2 (en) 2015-01-09 2018-11-27 Glenmark Pharmaceuticals Limited Process for preparation of ospemifene
EA039048B1 (ru) 2016-03-15 2021-11-26 Сионоги Энд Ко., Лтд. Способ получения производных феноксиэтанола
KR20240041745A (ko) 2022-09-23 2024-04-01 김민정 입체음향 베개

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Also Published As

Publication number Publication date
US20110015448A1 (en) 2011-01-20
EP2518039A1 (en) 2012-10-31
RU2465261C2 (ru) 2012-10-27
HK1139379A1 (en) 2010-09-17
EP2821385B1 (en) 2016-07-27
WO2008099059A1 (en) 2008-08-21
US20080207956A1 (en) 2008-08-28
CA2677861C (en) 2015-05-19
HRP20141107T1 (hr) 2015-01-02
EP2821385A2 (en) 2015-01-07
US8293947B2 (en) 2012-10-23
ES2590262T3 (es) 2016-11-21
BRPI0823326B1 (pt) 2021-06-29
BRPI0823326A2 (pt) 2013-10-15
KR20090110862A (ko) 2009-10-22
EP2518039A9 (en) 2013-02-13
EP2121553B1 (en) 2012-06-27
AU2008214530A1 (en) 2008-08-21
RU2009134131A (ru) 2011-03-20
PL2121553T3 (pl) 2012-11-30
JP5363344B2 (ja) 2013-12-11
BRPI0807675A2 (pt) 2011-09-13
HK1206003A1 (zh) 2015-12-31
KR101510646B1 (ko) 2015-04-10
AU2008214530B2 (en) 2012-04-26
EP2821385A3 (en) 2015-02-25
SI2518039T1 (sl) 2015-02-27
EP2518039B8 (en) 2014-12-17
CN101636372B (zh) 2013-03-27
CY1113184T1 (el) 2016-04-13
US7812197B2 (en) 2010-10-12
PT2121553E (pt) 2012-07-26
EP2121553A1 (en) 2009-11-25
MX2009008660A (es) 2009-10-13
EP2518039B1 (en) 2014-08-27
BRPI0807675B1 (pt) 2021-05-18
DK2121553T3 (da) 2012-07-23
CN101636372A (zh) 2010-01-27
JP2010518150A (ja) 2010-05-27
ES2524002T3 (es) 2014-12-03
CA2677861A1 (en) 2008-08-21
ES2389961T3 (es) 2012-11-05

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