SI1937262T1 - Spojina za uporabo pri zdravljenju gastrointestinalne dismotilitete - Google Patents

Spojina za uporabo pri zdravljenju gastrointestinalne dismotilitete

Info

Publication number
SI1937262T1
SI1937262T1 SI200632340T SI200632340T SI1937262T1 SI 1937262 T1 SI1937262 T1 SI 1937262T1 SI 200632340 T SI200632340 T SI 200632340T SI 200632340 T SI200632340 T SI 200632340T SI 1937262 T1 SI1937262 T1 SI 1937262T1
Authority
SI
Slovenia
Prior art keywords
composition
treating gastrointestinal
gastrointestinal dysmotility
dysmotility
treating
Prior art date
Application number
SI200632340T
Other languages
English (en)
Inventor
Rakesh Datta
Zheng Xin Dong
Original Assignee
Ipsen Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ipsen Pharma filed Critical Ipsen Pharma
Publication of SI1937262T1 publication Critical patent/SI1937262T1/sl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/2264Obesity-gene products, e.g. leptin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/25Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10Laxatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702Regulators; Modulating activity
    • C07K14/4705Regulators; Modulating activity stimulating, promoting or activating activity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/5759Products of obesity genes, e.g. leptin, obese (OB), tub, fat
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/60Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Endocrinology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Obesity (AREA)
  • Nutrition Science (AREA)
  • Otolaryngology (AREA)
  • Hospice & Palliative Care (AREA)
  • Child & Adolescent Psychology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
SI200632340T 2005-09-29 2006-09-28 Spojina za uporabo pri zdravljenju gastrointestinalne dismotilitete SI1937262T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US72191605P 2005-09-29 2005-09-29
EP06825239.4A EP1937262B1 (en) 2005-09-29 2006-09-28 Composition for use in treating gastrointestinal dysmotility
PCT/US2006/038027 WO2007041278A2 (en) 2005-09-29 2006-09-28 Composition and methods for stimulating gastrointestinal motility

Publications (1)

Publication Number Publication Date
SI1937262T1 true SI1937262T1 (sl) 2019-09-30

Family

ID=37906731

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200632340T SI1937262T1 (sl) 2005-09-29 2006-09-28 Spojina za uporabo pri zdravljenju gastrointestinalne dismotilitete

Country Status (14)

Country Link
US (6) US7932231B2 (sl)
EP (2) EP1937262B1 (sl)
JP (4) JP5230430B2 (sl)
CN (3) CN103251933A (sl)
CA (1) CA2625447C (sl)
CY (1) CY1122134T1 (sl)
DK (1) DK1937262T3 (sl)
ES (1) ES2740108T3 (sl)
HU (1) HUE044391T2 (sl)
PL (1) PL1937262T3 (sl)
PT (1) PT1937262T (sl)
RU (2) RU2566708C2 (sl)
SI (1) SI1937262T1 (sl)
WO (1) WO2007041278A2 (sl)

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CA2625920C (en) * 2005-09-28 2014-12-23 Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R Analogs of ghrelin
CN103251933A (zh) * 2005-09-29 2013-08-21 益普生制药股份有限公司 用于刺激胃肠运动性的组合物和方法
CN101657436A (zh) 2007-02-09 2010-02-24 特兰齐姆制药公司 大环生长素释放肽受体调节剂及其使用方法
TW200916113A (en) 2007-08-08 2009-04-16 Sod Conseils Rech Applic Method for inhibiting inflammation and pro-inflammatory cytokine/chemokine expression using a ghrelin analogue
AU2013201451B2 (en) * 2007-08-08 2015-07-30 Ipsen Pharma S.A.S. Method for inhibiting inflammation and pre-inflammatory cytokine/chemokine expression using a ghrelin analogue
CN101951937A (zh) * 2007-12-21 2011-01-19 赫尔辛医疗股份公司 使用伊帕瑞林刺激胃肠***动力的方法
US8772229B2 (en) 2008-10-03 2014-07-08 The Johns Hopkins University Methods for synthesis and uses of inhibitors of ghrelin O-acyltransferase as potential therapeutic agents for obesity and diabetes
UA104945C2 (uk) * 2010-03-15 2014-03-25 Іпсен Фарма С.А.С. Фармацевтична композиція лігандів рецепторів секретагогів гормону росту
RU2475757C1 (ru) * 2012-02-02 2013-02-20 Государственное бюджетное образовательное учреждение высшего профессионального образования "Пермская государственная медицинская академия имени академика Е.А. Вагнера" Министерства здравоохранения и социального развития Российской Федерации Способ прогнозирования тяжести течения послеоперационного периода у больных калькулезным холециститом
EP2809339A2 (en) * 2012-02-03 2014-12-10 Zealand Pharma A/S Ghrelin analogues
WO2014156339A1 (ja) * 2013-03-25 2014-10-02 ゼリア新薬工業株式会社 食後期の胃運動亢進剤
CN106459149A (zh) 2014-03-04 2017-02-22 莫图斯治疗公司 H‑inp‑(d)bal‑(d)trp‑phe‑apc‑nh2及其可药用盐的液相合成的方法
CN113072617B (zh) * 2021-03-30 2023-08-08 成都诺和晟泰生物科技有限公司 一种多肽化合物及其应用
CN114805487B (zh) * 2022-06-07 2024-03-12 成都诺和晟泰生物科技有限公司 一种多肽化合物及其应用

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US4962115A (en) 1981-10-01 1990-10-09 Janssen Pharmaceutica N.V. Novel N-(3-hydroxy-4-piperidinyl)benzamide derivatives
US5362756A (en) 1989-02-20 1994-11-08 Riviere Pierre J M Use of fedotozine in the treatment of functional states of intestinal obstructions
US5264565A (en) 1991-01-22 1993-11-23 Affymax Technologies, N.V. Nucleic acid encoding the D2 /Ml chimeric receptor
RU2185393C2 (ru) 1993-01-06 2002-07-20 Кинертон Лимитед Сложный полиэфир и конъюгат на его основе
IL120424A0 (en) 1995-07-26 1997-07-13 Nps Pharma Inc Chimeric receptors and methods for identifying compounds active at metabotropic glutamate receptors and the use of such compounds in the treatment of neurological disorders and diseases
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CA2625920C (en) 2005-09-28 2014-12-23 Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R Analogs of ghrelin
CN103251933A (zh) * 2005-09-29 2013-08-21 益普生制药股份有限公司 用于刺激胃肠运动性的组合物和方法
WO2007106385A2 (en) 2006-03-10 2007-09-20 Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S. Use of a ghrelin agonist to improve the catabolic effects of glucocorticoid treatment
RU2459831C2 (ru) 2006-09-27 2012-08-27 Ипсен Фарма С.А.С. Аналоги грелина с замещением на n-конце
TW200916113A (en) 2007-08-08 2009-04-16 Sod Conseils Rech Applic Method for inhibiting inflammation and pro-inflammatory cytokine/chemokine expression using a ghrelin analogue
UA104945C2 (uk) 2010-03-15 2014-03-25 Іпсен Фарма С.А.С. Фармацевтична композиція лігандів рецепторів секретагогів гормону росту
RU2625793C2 (ru) 2011-12-23 2017-07-19 Ипсен Мэньюфэкчеринг Айэлэнд Лимитед Способ синтеза терапевтических пептидов

Also Published As

Publication number Publication date
RU2008116837A (ru) 2009-11-10
EP1937262B1 (en) 2019-05-08
US20190248861A1 (en) 2019-08-15
RU2420305C2 (ru) 2011-06-10
CN101287464A (zh) 2008-10-15
JP5960563B2 (ja) 2016-08-02
PT1937262T (pt) 2019-08-21
EP3586846A1 (en) 2020-01-01
CA2625447C (en) 2015-06-09
EP1937262A2 (en) 2008-07-02
CY1122134T1 (el) 2020-11-25
RU2011103062A (ru) 2012-08-10
CN103251933A (zh) 2013-08-21
US20170037104A1 (en) 2017-02-09
WO2007041278A3 (en) 2007-10-04
JP5230430B2 (ja) 2013-07-10
RU2566708C2 (ru) 2015-10-27
US9499599B2 (en) 2016-11-22
PL1937262T3 (pl) 2019-10-31
US20090304724A1 (en) 2009-12-10
CN105381453A (zh) 2016-03-09
JP2013035856A (ja) 2013-02-21
HUE044391T2 (hu) 2019-10-28
JP2015038116A (ja) 2015-02-26
CA2625447A1 (en) 2007-04-12
JP6419864B2 (ja) 2018-11-07
CN105381453B (zh) 2018-11-13
WO2007041278A2 (en) 2007-04-12
US20200347110A1 (en) 2020-11-05
JP2017095494A (ja) 2017-06-01
DK1937262T3 (da) 2019-07-15
ES2740108T3 (es) 2020-02-05
US7932231B2 (en) 2011-04-26
US20110166069A1 (en) 2011-07-07
US8981054B2 (en) 2015-03-17
US20150218245A1 (en) 2015-08-06
EP1937262A4 (en) 2014-09-24
JP2009510098A (ja) 2009-03-12
WO2007041278B1 (en) 2007-12-06
CN105381453B9 (zh) 2019-01-11

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