SI1828239T1 - Proizvodnja fgf18 v prokariotskih gostiteljih - Google Patents

Proizvodnja fgf18 v prokariotskih gostiteljih

Info

Publication number
SI1828239T1
SI1828239T1 SI200531396T SI200531396T SI1828239T1 SI 1828239 T1 SI1828239 T1 SI 1828239T1 SI 200531396 T SI200531396 T SI 200531396T SI 200531396 T SI200531396 T SI 200531396T SI 1828239 T1 SI1828239 T1 SI 1828239T1
Authority
SI
Slovenia
Prior art keywords
fgf18
coli
production
expression
ompt
Prior art date
Application number
SI200531396T
Other languages
English (en)
Inventor
Brian J Reardon
Susan D Julien
Chung-Leung Chan
Hong Y Liu
Original Assignee
Zymogenetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zymogenetics Inc filed Critical Zymogenetics Inc
Publication of SI1828239T1 publication Critical patent/SI1828239T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/50—Fibroblast growth factor [FGF]
    • C07K14/501—Fibroblast growth factor [FGF] acidic FGF [aFGF]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/50—Fibroblast growth factor [FGF]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
SI200531396T 2004-12-10 2005-12-12 Proizvodnja fgf18 v prokariotskih gostiteljih SI1828239T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US63502304P 2004-12-10 2004-12-10
EP05853969A EP1828239B1 (en) 2004-12-10 2005-12-12 Fgf18 production in prokaryotic hosts
PCT/US2005/045166 WO2006063362A1 (en) 2004-12-10 2005-12-12 Fgf18 production in prokaryotic hosts

Publications (1)

Publication Number Publication Date
SI1828239T1 true SI1828239T1 (sl) 2011-11-30

Family

ID=36061577

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200531396T SI1828239T1 (sl) 2004-12-10 2005-12-12 Proizvodnja fgf18 v prokariotskih gostiteljih

Country Status (13)

Country Link
US (1) US7858341B2 (sl)
EP (1) EP1828239B1 (sl)
AT (1) ATE521633T1 (sl)
AU (1) AU2005314438B2 (sl)
CA (1) CA2592261C (sl)
CY (1) CY1112394T1 (sl)
DK (1) DK1828239T3 (sl)
ES (1) ES2371219T3 (sl)
HK (1) HK1113161A1 (sl)
PL (1) PL1828239T3 (sl)
PT (1) PT1828239E (sl)
SI (1) SI1828239T1 (sl)
WO (1) WO2006063362A1 (sl)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1931704T3 (da) * 2005-10-04 2011-03-14 Zymogenetics L L C Frembringelse og rensning af IL-29
SI2054050T1 (sl) * 2006-08-25 2012-12-31 Ares Trading S.A. Zdravljenje hrustanäśnih obolenj z fgf-18
WO2008023063A2 (en) 2006-08-25 2008-02-28 Ares Trading S.A. Treatment of cartilage disorders with fgf-18
MX2011013417A (es) 2009-06-25 2012-03-29 Amgen Inc Procesos de purificacion por captura para proteinas expresadas en un sistema no mamifero.
WO2012038953A2 (en) 2010-09-21 2012-03-29 Hepacore Ltd. Fgf-18 truncated variants having increased receptor specificity and uses thereof
WO2012140650A2 (en) 2011-04-12 2012-10-18 Hepacore Ltd. Conjugates of carboxy polysaccharides with fibroblast growth factors and variants thereof
TW201307563A (zh) * 2011-05-19 2013-02-16 Shire Human Genetic Therapies 純化乙醯肝素－ｎ－硫酸酯酶之方法
TWI527590B (zh) 2011-06-17 2016-04-01 艾瑞斯貿易公司 Ｆｇｆ－１８之凍乾調配物
US9580692B2 (en) * 2012-02-29 2017-02-28 Ge Healthcare Bioprocess R&D Ab Method for endotoxin removal
US10041050B2 (en) 2012-02-29 2018-08-07 Ge Healthcare Bioprocess R&D Ab Method for endotoxin removal
CN104736723B (zh) 2012-08-06 2017-10-31 默克专利有限公司 用于预测对fgf‑18化合物的响应性的遗传标记
CA2938796C (en) * 2014-02-20 2022-08-02 Merck Patent Gmbh Implant comprising fgf-18
KR101608734B1 (ko) 2014-03-21 2016-04-04 씨제이제일제당 주식회사 L-아미노산을 생산하는 미생물 및 이를 이용하여 l-아미노산을 생산하는 방법
CA2971315C (en) 2015-01-29 2023-02-14 Ares Trading S.A. Immunoassays for high positively charged proteins
EP3957654A1 (en) * 2015-07-15 2022-02-23 Prosit Sole Biotechnology (Beijing) Co., Ltd Fusion polypeptides and methods of use
ES2918249T3 (es) 2017-09-29 2022-07-14 Merck Patent Gmbh Biomarcadores inflamatorios para predecir la capacidad de respuesta al compuesto FGF-18
PL3687558T3 (pl) 2017-09-29 2022-07-18 Merck Patent Gmbh Biomarkery metaboliczne do przewidywania podatności na leczenie związkiem fgf-18
CN110759986B (zh) * 2019-10-18 2023-01-31 大连工业大学 一种可逆自组装蛋白的高效制备方法
CN114181321B (zh) * 2021-12-10 2023-04-11 中国海洋大学 花鲈fgf6a、fgf6b以及fgf18重组蛋白及其制备方法和应用
WO2024084807A1 (ja) * 2022-10-19 2024-04-25 学校法人東邦大学 線維芽細胞増殖因子１８の測定方法及び測定用試薬

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5439818A (en) 1985-09-12 1995-08-08 Scios Nova Inc. DNA encoding human recombinant basic fibroblast growth factor
US5604293A (en) 1985-09-12 1997-02-18 Scios Inc. Recombinant human basic fibroblast growth factor
US5773252A (en) 1995-06-05 1998-06-30 Human Genome Sciences, Inc. Fibroblast growth factor 15
US20050043234A1 (en) 1996-10-16 2005-02-24 Deisher Theresa A. Novel FGF homologs
IL129379A (en) 1996-10-16 2008-12-29 Zymogenetics Inc Fibroblast growth factor homologues
US7135459B2 (en) 1996-10-16 2006-11-14 Zymogenetics, Inc. Methods of use of FGF homologs
US6518236B1 (en) 1996-10-16 2003-02-11 Zymogenetics, Inc. FGF homologs
WO2001039788A2 (en) 1999-12-02 2001-06-07 Zymogenetics, Inc. Methods for targeting cells that express fibroblast growth receptor-3 or-2
AU2003279835B2 (en) 2002-10-07 2009-09-10 Zymogenetics, Inc. Methods of administering FGF18
US20040229292A1 (en) 2002-11-26 2004-11-18 Sebastiano Cavallaro Use of FGF-18 in the diagnosis and treatment of memory disorders

Also Published As

Publication number Publication date
HK1113161A1 (en) 2008-09-26
WO2006063362A1 (en) 2006-06-15
AU2005314438A1 (en) 2006-06-15
PL1828239T3 (pl) 2012-01-31
AU2005314438B2 (en) 2012-03-29
PT1828239E (pt) 2011-10-27
US20060172384A1 (en) 2006-08-03
US7858341B2 (en) 2010-12-28
CA2592261C (en) 2015-11-24
EP1828239A1 (en) 2007-09-05
EP1828239B1 (en) 2011-08-24
CY1112394T1 (el) 2015-12-09
DK1828239T3 (da) 2011-12-19
CA2592261A1 (en) 2006-06-15
ATE521633T1 (de) 2011-09-15
ES2371219T3 (es) 2011-12-28

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