SI1592416T1 - Maščobne kisline s srednjo dolžino verige, gliceridi in analogi kot stimulatorji eritropoeze - Google Patents
Maščobne kisline s srednjo dolžino verige, gliceridi in analogi kot stimulatorji eritropoezeInfo
- Publication number
- SI1592416T1 SI1592416T1 SI200431064T SI200431064T SI1592416T1 SI 1592416 T1 SI1592416 T1 SI 1592416T1 SI 200431064 T SI200431064 T SI 200431064T SI 200431064 T SI200431064 T SI 200431064T SI 1592416 T1 SI1592416 T1 SI 1592416T1
- Authority
- SI
- Slovenia
- Prior art keywords
- erythropoiesis
- stimulators
- glycerides
- analogues
- medium
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Emergency Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US44545403P | 2003-02-07 | 2003-02-07 | |
PCT/GB2004/000457 WO2004069237A1 (en) | 2003-02-07 | 2004-02-06 | Medium-chain length fatty acids, glycerides and analogues as stimulators of erythropoiesis |
EP04708802A EP1592416B1 (en) | 2003-02-07 | 2004-02-06 | Medium-chain length fatty acids, glycerides and analogues as stimulators of erythropoiesis |
Publications (1)
Publication Number | Publication Date |
---|---|
SI1592416T1 true SI1592416T1 (sl) | 2009-06-30 |
Family
ID=32850990
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI200431064T SI1592416T1 (sl) | 2003-02-07 | 2004-02-06 | Maščobne kisline s srednjo dolžino verige, gliceridi in analogi kot stimulatorji eritropoeze |
Country Status (28)
Country | Link |
---|---|
US (1) | US9682054B2 (sl) |
EP (1) | EP1592416B1 (sl) |
JP (1) | JP5390070B2 (sl) |
KR (1) | KR101120775B1 (sl) |
CN (1) | CN100427081C (sl) |
AP (1) | AP2005003367A0 (sl) |
AR (1) | AR043120A1 (sl) |
AT (1) | ATE419846T1 (sl) |
AU (1) | AU2004210193B2 (sl) |
BR (1) | BRPI0407276A (sl) |
CA (1) | CA2515160C (sl) |
CY (1) | CY1108963T1 (sl) |
DE (2) | DE04708802T1 (sl) |
DK (1) | DK1592416T3 (sl) |
EA (1) | EA009939B1 (sl) |
ES (1) | ES2255467T3 (sl) |
IL (1) | IL170057A (sl) |
JO (1) | JO2705B1 (sl) |
MA (1) | MA27664A1 (sl) |
MX (1) | MXPA05008382A (sl) |
MY (1) | MY140913A (sl) |
NO (1) | NO334085B1 (sl) |
NZ (1) | NZ541593A (sl) |
PT (1) | PT1592416E (sl) |
SI (1) | SI1592416T1 (sl) |
TN (1) | TNSN05189A1 (sl) |
WO (1) | WO2004069237A1 (sl) |
ZA (1) | ZA200506246B (sl) |
Families Citing this family (33)
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NZ528690A (en) | 2001-04-18 | 2005-08-26 | Prometic Biosciences Inc | Medium-chain length fatty acids, glycerides and analogues as neutrophil survival and activation factors |
JP2007532629A (ja) * | 2004-04-15 | 2007-11-15 | キアスマ, インコーポレイテッド | 生物学的障壁を横切る透過を促進し得る組成物 |
US20070219131A1 (en) * | 2004-04-15 | 2007-09-20 | Ben-Sasson Shmuel A | Compositions capable of facilitating penetration across a biological barrier |
EP2314617B1 (en) | 2004-07-23 | 2015-06-24 | Acceleron Pharma Inc. | ActRII receptor polypeptides |
JP2008511553A (ja) * | 2004-09-03 | 2008-04-17 | プロメティック バイオサイエンシズ インコーポレーテッド | 免疫調節活性および化学防護活性を有する置換型プリニル誘導体ならびにその単独使用または中鎖長の脂肪酸もしくはグリセリドとの併用 |
US8071580B2 (en) | 2004-10-01 | 2011-12-06 | Prometic Biosciences Inc. | Medium-chain length fatty alcohols as stimulators of hematopoiesis |
PT1804780E (pt) * | 2004-10-01 | 2012-01-19 | Prometic Biosciences Inc | Álcoois gordos com comprimento médio da cadeia como estimuladores da hematopoiese |
EP1973559B1 (en) | 2005-11-23 | 2013-01-09 | Acceleron Pharma Inc. | Activin-actriia antagonists and uses for promoting bone growth |
US8128933B2 (en) | 2005-11-23 | 2012-03-06 | Acceleron Pharma, Inc. | Method of promoting bone growth by an anti-activin B antibody |
US8895016B2 (en) | 2006-12-18 | 2014-11-25 | Acceleron Pharma, Inc. | Antagonists of activin-actriia and uses for increasing red blood cell levels |
CA2677007A1 (en) | 2007-02-01 | 2008-08-07 | Acceleron Pharma Inc. | Activin-actriia antagonists and uses for treating or preventing breast cancer |
TW201803890A (zh) | 2007-02-02 | 2018-02-01 | 艾瑟勒朗法瑪公司 | 衍生自ActRIIB的變體與其用途 |
CA3039330C (en) | 2007-02-09 | 2021-11-09 | Acceleron Pharma Inc. | Activin-actriia antagonists and uses for promoting bone growth in cancer patients |
CN103877564A (zh) | 2007-09-18 | 2014-06-25 | 阿塞勒隆制药公司 | 活化素-actriia拮抗剂和减少或抑制fsh分泌的用途 |
MX338513B (es) | 2007-11-02 | 2016-04-20 | Prometic Pharma Smt Ltd | Acidos grasos de longitud de cadena mediana y gliceridos como agentes de nefroprotección. |
BRPI0821395A2 (pt) * | 2007-12-19 | 2015-06-16 | Prometic Biosciences Inc | Triglicerídeos, sais e ácidos graxos de cadeia média em combinação com gemcitabina para tratamento de câncer pancreático |
DK2340031T3 (da) | 2008-08-14 | 2019-07-15 | Acceleron Pharma Inc | Gdf-fanger til anvendelse ved behandling af anæmi |
US8216997B2 (en) | 2008-08-14 | 2012-07-10 | Acceleron Pharma, Inc. | Methods for increasing red blood cell levels and treating anemia using a combination of GDF traps and erythropoietin receptor activators |
JP5623406B2 (ja) | 2008-09-17 | 2014-11-12 | キアズマ インコーポレイテッド | 医薬組成物および関連する送達方法 |
MX2011013172A (es) | 2009-06-08 | 2012-04-02 | Acceleron Pharma Inc | Metodos para aumentar adipocitos termogenicos. |
KR20120028358A (ko) | 2009-06-12 | 2012-03-22 | 악셀레론 파마 인코포레이티드 | 절두된 ActRIIB-FC 융합 단백질 |
IL287990B (en) * | 2009-08-13 | 2022-07-01 | Acceleron Pharma Inc | Combined use of gdf traps and erythropoietin receptor activators to increase red blood cell levels |
EP3332796A1 (en) | 2009-11-17 | 2018-06-13 | Acceleron Pharma Inc. | Actriib proteins and variants and uses therefore relating to utrophin induction for muscular dystrophy therapy |
CA2817008A1 (en) | 2010-11-08 | 2012-05-18 | Acceleron Pharma Inc. | Actriia binding agents and uses thereof |
TWI572352B (zh) * | 2012-03-01 | 2017-03-01 | 波麥堤克藥學Smt有限公司 | 用於製備具中鏈長度之脂肪酸的三酸甘油酯之方法 |
KR20210091358A (ko) | 2012-11-02 | 2021-07-21 | 셀진 코포레이션 | 골 및 다른 장애를 치료하기 위한 액티빈-actrii 길항제 및 용도 |
CN102973922B (zh) * | 2012-12-18 | 2016-02-03 | 华东理工大学 | 一种融合蛋白的应用 |
WO2015192111A1 (en) | 2014-06-13 | 2015-12-17 | Acceleron Pharma, Inc. | Methods and compositions for treating ulcers |
MA41052A (fr) | 2014-10-09 | 2017-08-15 | Celgene Corp | Traitement d'une maladie cardiovasculaire à l'aide de pièges de ligands d'actrii |
PT3227675T (pt) | 2014-12-03 | 2023-05-30 | Celgene Corp | Antagonistas da ativina-actrii e utilizações para tratamento da síndrome mielodisplásica |
WO2016126830A1 (en) | 2015-02-03 | 2016-08-11 | Chiasma Inc. | Method of treating diseases |
US20170021029A1 (en) * | 2015-04-15 | 2017-01-26 | Jeffrey Charles Raber | Topical formulations and uses |
US11141457B1 (en) | 2020-12-28 | 2021-10-12 | Amryt Endo, Inc. | Oral octreotide therapy and contraceptive methods |
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US4871768A (en) | 1984-07-12 | 1989-10-03 | New England Deaconess Hospital Corporation | Dietary supplement utilizing ω-3/medium chain trigylceride mixtures |
US6060459A (en) | 1987-10-28 | 2000-05-09 | Pro-Neuron, Inc. | Enhancing blood cell count with oxypurine nucleosides |
US5011852A (en) | 1988-07-25 | 1991-04-30 | Applied Analytical Industries, Inc. | Liquid oral pharmaceutical compositions of non-steroidal anti-inflammatory drugs |
JP3014119B2 (ja) * | 1990-05-28 | 2000-02-28 | 雪印乳業株式会社 | 直腸投与用赤血球造血剤 |
JP3249147B2 (ja) | 1990-06-01 | 2002-01-21 | キリン−アムジエン・インコーポレーテツド | 生理活性蛋白含有経口製剤 |
ATE147976T1 (de) * | 1991-01-15 | 1997-02-15 | Hemosphere Inc | Protein nanomatrizen und verfahren zur herstellung |
JPH05163160A (ja) | 1991-12-13 | 1993-06-29 | Snow Brand Milk Prod Co Ltd | 免疫低下に伴う感染症の予防及び治療用栄養剤 |
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US5318781A (en) * | 1993-04-06 | 1994-06-07 | Hoffmann-La Roche Inc. | Absorption enhancement of antibiotics |
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WO1995030413A1 (fr) * | 1994-05-10 | 1995-11-16 | The Kitasato Institute | Accelerateur de proliferation de cellules souches hematopoietiques |
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IT1275802B1 (it) | 1994-11-03 | 1997-10-17 | Hoffmann La Roche | Composizione di interferone |
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AUPN933396A0 (en) | 1996-04-17 | 1996-05-09 | Pfizer Pty Limited | Non-aqueuos oral-drench compositions containing avermectin compounds |
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JPH10265380A (ja) | 1997-03-17 | 1998-10-06 | Bristol Myers Squibb Co | 抗ガン剤 |
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PT937456E (pt) * | 1998-02-23 | 2004-10-29 | Cilag Ag Int | Dispersao lipossomal de eritropoietina |
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US6267985B1 (en) | 1999-06-30 | 2001-07-31 | Lipocine Inc. | Clear oil-containing pharmaceutical compositions |
US6479540B1 (en) | 1999-09-27 | 2002-11-12 | Sonus Pharmaceuticals, Inc. | Compositions of tocol-soluble therapeutics |
US6835750B1 (en) | 2000-05-01 | 2004-12-28 | Accera, Inc. | Use of medium chain triglycerides for the treatment and prevention of alzheimer's disease and other diseases resulting from reduced neuronal metabolism II |
WO2001095914A1 (en) | 2000-06-14 | 2001-12-20 | William Leslie Porter | Lipids for modulating immune response |
US6967028B2 (en) | 2000-07-31 | 2005-11-22 | Mainelab | Prolonged release microspheres for injectable administration |
IL142535A0 (en) | 2001-04-11 | 2002-03-10 | Yeda Res & Dev | Pharmaceutical compositions for the treatment of inflammation |
NZ528690A (en) * | 2001-04-18 | 2005-08-26 | Prometic Biosciences Inc | Medium-chain length fatty acids, glycerides and analogues as neutrophil survival and activation factors |
US20040052836A1 (en) | 2002-09-13 | 2004-03-18 | Li Luk Chiu | Pharmaceutical compositions containing at least one stable liposphere having an improved shelf life |
US6725510B1 (en) | 2003-04-25 | 2004-04-27 | Almetta Clyburn | Inclining coffin |
KR101120813B1 (ko) | 2003-07-25 | 2012-03-23 | 프로메틱 바이오사이언시즈 인코포레이티드 | 중-쇄 지방산 금속염의 제조 방법 |
JP2008511553A (ja) | 2004-09-03 | 2008-04-17 | プロメティック バイオサイエンシズ インコーポレーテッド | 免疫調節活性および化学防護活性を有する置換型プリニル誘導体ならびにその単独使用または中鎖長の脂肪酸もしくはグリセリドとの併用 |
US8071580B2 (en) | 2004-10-01 | 2011-12-06 | Prometic Biosciences Inc. | Medium-chain length fatty alcohols as stimulators of hematopoiesis |
-
2004
- 2004-02-06 WO PCT/GB2004/000457 patent/WO2004069237A1/en active IP Right Grant
- 2004-02-06 AU AU2004210193A patent/AU2004210193B2/en not_active Ceased
- 2004-02-06 CN CNB200480004978XA patent/CN100427081C/zh not_active Expired - Fee Related
- 2004-02-06 SI SI200431064T patent/SI1592416T1/sl unknown
- 2004-02-06 DE DE04708802T patent/DE04708802T1/de active Pending
- 2004-02-06 US US10/544,350 patent/US9682054B2/en active Active
- 2004-02-06 AT AT04708802T patent/ATE419846T1/de active
- 2004-02-06 AP AP2005003367A patent/AP2005003367A0/xx unknown
- 2004-02-06 JP JP2006502243A patent/JP5390070B2/ja not_active Expired - Fee Related
- 2004-02-06 CA CA2515160A patent/CA2515160C/en not_active Expired - Fee Related
- 2004-02-06 BR BR0407276-6A patent/BRPI0407276A/pt not_active Application Discontinuation
- 2004-02-06 MX MXPA05008382A patent/MXPA05008382A/es active IP Right Grant
- 2004-02-06 ZA ZA200506246A patent/ZA200506246B/en unknown
- 2004-02-06 DK DK04708802T patent/DK1592416T3/da active
- 2004-02-06 DE DE602004018902T patent/DE602004018902D1/de not_active Expired - Lifetime
- 2004-02-06 AR ARP040100385A patent/AR043120A1/es not_active Application Discontinuation
- 2004-02-06 EA EA200501267A patent/EA009939B1/ru not_active IP Right Cessation
- 2004-02-06 ES ES04708802T patent/ES2255467T3/es not_active Expired - Lifetime
- 2004-02-06 NZ NZ541593A patent/NZ541593A/xx not_active IP Right Cessation
- 2004-02-06 KR KR1020057014499A patent/KR101120775B1/ko active IP Right Grant
- 2004-02-06 EP EP04708802A patent/EP1592416B1/en not_active Expired - Lifetime
- 2004-02-06 PT PT04708802T patent/PT1592416E/pt unknown
- 2004-02-07 MY MYPI20040371A patent/MY140913A/en unknown
- 2004-02-24 JO JOP/2004/0017A patent/JO2705B1/ar active
-
2005
- 2005-08-03 TN TNP2005000189A patent/TNSN05189A1/en unknown
- 2005-08-03 IL IL170057A patent/IL170057A/en active IP Right Grant
- 2005-08-26 NO NO20053994A patent/NO334085B1/no not_active IP Right Cessation
- 2005-09-05 MA MA28479A patent/MA27664A1/fr unknown
-
2009
- 2009-04-06 CY CY20091100397T patent/CY1108963T1/el unknown
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