SI0996430T1 - Nucleotide analog compositions - Google Patents

Nucleotide analog compositions

Info

Publication number
SI0996430T1
SI0996430T1 SI9830329T SI9830329T SI0996430T1 SI 0996430 T1 SI0996430 T1 SI 0996430T1 SI 9830329 T SI9830329 T SI 9830329T SI 9830329 T SI9830329 T SI 9830329T SI 0996430 T1 SI0996430 T1 SI 0996430T1
Authority
SI
Slovenia
Prior art keywords
nucleotide analog
analog compositions
compositions
nucleotide
analog
Prior art date
Application number
SI9830329T
Other languages
English (en)
Slovenian (sl)
Inventor
Murty N. Arimilli
Thomas T. K. Lee
Lawrence V. Manes
John D. Munger Jr.
Ernest J. Prisbe
Lisa M. Schultze
Daphne E. Kelly
Original Assignee
Gilead Sciences, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gilead Sciences, Inc. filed Critical Gilead Sciences, Inc.
Priority claimed from PCT/US1998/015304 external-priority patent/WO1999004774A2/en
Publication of SI0996430T1 publication Critical patent/SI0996430T1/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/675Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C07F9/65616Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SI9830329T 1997-07-25 1998-07-23 Nucleotide analog compositions SI0996430T1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US5377197P 1997-07-25 1997-07-25
US90074597A 1997-07-25 1997-07-25
PCT/US1998/015304 WO1999004774A2 (en) 1997-07-25 1998-07-23 Nucleotide analog compositions
EP98937988A EP0996430B1 (en) 1997-07-25 1998-07-23 Nucleotide analog compositions

Publications (1)

Publication Number Publication Date
SI0996430T1 true SI0996430T1 (en) 2003-04-30

Family

ID=36747399

Family Applications (1)

Application Number Title Priority Date Filing Date
SI9830329T SI0996430T1 (en) 1997-07-25 1998-07-23 Nucleotide analog compositions

Country Status (4)

Country Link
EP (2) EP1256584B1 (xx)
CN (5) CN1900091A (xx)
DK (1) DK1256584T3 (xx)
SI (1) SI0996430T1 (xx)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2004206821C1 (en) 2003-01-14 2009-10-01 Gilead Sciences, Inc. Compositions and methods for combination antiviral therapy
TWI375560B (en) 2005-06-13 2012-11-01 Gilead Sciences Inc Composition comprising dry granulated emtricitabine and tenofovir df and method for making the same
TWI471145B (zh) 2005-06-13 2015-02-01 Bristol Myers Squibb & Gilead Sciences Llc 單一式藥學劑量型
CN101704846B (zh) * 2009-12-03 2012-05-09 华东理工大学 9-(2-磷酰甲氧基乙基)-腺嘌呤的结晶体及其制备方法
CN101891767B (zh) * 2010-07-21 2012-05-23 浙江贝得药业有限公司 一种阿德福韦酯的制备方法
CN103333208B (zh) * 2013-06-04 2016-05-11 广州晶莱医药科技有限公司 阿德福韦酯马来酸盐及其制备方法和组合物
CN110172074A (zh) * 2019-01-16 2019-08-27 湖北益泰药业股份有限公司 一种阿德福韦酯的合成方法
CN110143983A (zh) * 2019-06-26 2019-08-20 北京济美堂医药研究有限公司 一种高稳定性阿德福韦酯的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CS264222B1 (en) * 1986-07-18 1989-06-13 Holy Antonin N-phosphonylmethoxyalkylderivatives of bases of pytimidine and purine and method of use them
DK0481214T3 (da) * 1990-09-14 1999-02-22 Acad Of Science Czech Republic Prolægemidler af phosphonater
US5514798A (en) * 1993-06-02 1996-05-07 Gilead Sciences, Inc. Method and cyclic carbonates for nucleotide analogues
ATE199906T1 (de) * 1993-06-29 2001-04-15 Mitsubishi Chem Corp Phosphonat-nukleotid ester-derivate

Also Published As

Publication number Publication date
EP1256584B1 (en) 2004-09-29
CN1763056A (zh) 2006-04-26
EP1256584A1 (en) 2002-11-13
DK1256584T3 (da) 2004-12-06
CN1900089A (zh) 2007-01-24
CN1900090A (zh) 2007-01-24
CN1763057A (zh) 2006-04-26
CN1763057B (zh) 2012-10-17
CN1900091A (zh) 2007-01-24
EP1256585B1 (en) 2004-09-29
CN1763056B (zh) 2013-01-16
EP1256585A1 (en) 2002-11-13

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