SG48415A1 - Process for the purification of a 3-cephem-4-carboxylic acid derivative - Google Patents

Process for the purification of a 3-cephem-4-carboxylic acid derivative

Info

Publication number
SG48415A1
SG48415A1 SG1996009496A SG1996009496A SG48415A1 SG 48415 A1 SG48415 A1 SG 48415A1 SG 1996009496 A SG1996009496 A SG 1996009496A SG 1996009496 A SG1996009496 A SG 1996009496A SG 48415 A1 SG48415 A1 SG 48415A1
Authority
SG
Singapore
Prior art keywords
cephem
carboxylic acid
purification
acid derivative
ylü
Prior art date
Application number
SG1996009496A
Other languages
English (en)
Inventor
Johannes Ludescher
Bernhard Prager
Siegfried Wolf
Original Assignee
Biochemie Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AT0019192A external-priority patent/AT399876B/de
Priority claimed from GB929225666A external-priority patent/GB9225666D0/en
Application filed by Biochemie Gmbh filed Critical Biochemie Gmbh
Publication of SG48415A1 publication Critical patent/SG48415A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/22—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SG1996009496A 1992-02-05 1992-12-21 Process for the purification of a 3-cephem-4-carboxylic acid derivative SG48415A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AT0019192A AT399876B (de) 1992-02-05 1992-02-05 Verfahren zur abreicherung von 7-amino-3-((e)-1- propen-1-yl)-3-cephem-4-carbonsäure
GB929225666A GB9225666D0 (en) 1992-12-09 1992-12-09 Process for the depletion of 7-amino-3-((e)-propen-1-yl)-3-cephem-4-carboxylic acid

Publications (1)

Publication Number Publication Date
SG48415A1 true SG48415A1 (en) 1998-04-17

Family

ID=25591794

Family Applications (1)

Application Number Title Priority Date Filing Date
SG1996009496A SG48415A1 (en) 1992-02-05 1992-12-21 Process for the purification of a 3-cephem-4-carboxylic acid derivative

Country Status (14)

Country Link
US (3) US5869648A (zh)
EP (2) EP1103555B1 (zh)
JP (1) JP2825655B2 (zh)
KR (1) KR950700311A (zh)
AT (2) ATE253583T1 (zh)
CA (1) CA2124322C (zh)
DE (2) DE69232048T2 (zh)
DK (1) DK0630380T3 (zh)
ES (2) ES2210047T3 (zh)
GR (1) GR3036985T3 (zh)
PT (1) PT630380E (zh)
SG (1) SG48415A1 (zh)
TW (1) TW230775B (zh)
WO (1) WO1993016084A1 (zh)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE198892T1 (de) 1993-11-17 2001-02-15 Biochemie Gmbh Trennung von cephalosporinisomeren
US5648378A (en) * 1995-06-07 1997-07-15 Research Corporation Technologies, Inc. 2-iminochromene derivatives as inhibitors of protein tyrosine kinase
AT403049B (de) 1995-08-14 1997-10-27 Biochemie Gmbh Abreicherung von 7-adca in 3-vinyl-aca
AT405283B (de) * 1997-04-04 1999-06-25 Biochemie Gmbh Neues kristallines 7-(z)-(2-(2-aminothiazol-4-yl) -2-hydroxyiminoacetamido)-3-vinyl-3-cephem-4- carbonsäure dicyclohexylammoniumsalz und verfahren zu dessen herstellung
AT406773B (de) * 1998-04-02 2000-08-25 Biochemie Gmbh Neues salz von 7-(2-(aminothiazol-4yl)-2-
GB0118764D0 (en) * 2001-08-01 2001-09-26 Biochemie Gmbh Organic compounds
KR20050087776A (ko) * 2002-08-13 2005-08-31 산도즈 아게 세프디니르 중간체
US20060173176A1 (en) * 2002-10-08 2006-08-03 Yatendra Kumar Process for the preparation of (z)-isomer enriched 7-amino-3-propen-1-yl-3-cephem-4-carboxylic acid
US6903211B2 (en) * 2002-10-30 2005-06-07 Orchid Chemicals & Pharmaceuticals Limited Process for the preparation of 3-propenyl cephalosporin DMF solvate
ZA200507748B (en) * 2003-03-24 2007-03-28 Acs Dobfar Spa Novel crystal of 7-[2-(2-aminothiazole-4-yl)-2-hydroxyimino-acetamido-3-vinyl-3-cephem-4-carboxylic acid (syn isomer) and method for preparation thereof
WO2005100369A1 (en) * 2004-04-13 2005-10-27 Ranbaxy Laboratories Limited Depletion of e-isomers in preparation of z-enriched 3-(2-substituted vinyl) cephalosporins
JP4046708B2 (ja) * 2004-06-04 2008-02-13 明治製菓株式会社 ３−アルケニルセフェム化合物の製造方法
GB2421024A (en) * 2004-12-07 2006-06-14 Sandoz Ag Cefdinir crystalline form C
US20070128268A1 (en) * 2005-12-07 2007-06-07 Herwig Jennewein Pharmaceutical compositions comprising an antibiotic
EP2367118A1 (en) 2010-03-15 2011-09-21 GMC Software AG Method and devices for generating two-dimensional visual objects

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4107431A (en) * 1970-01-23 1978-08-15 Glaxo Laboratories Limited Δ3 -3-Vinyl or substituted vinyl-4-carboxy cephalosporins
US4110534A (en) * 1970-01-23 1978-08-29 Glaxo Laboratories Limited Process for the preparation of 3-vinyl and substituted vinyl cephalosporins
US3769277A (en) * 1970-01-23 1973-10-30 Glaxo Lab Ltd Preparation of delta3-4 carboxy cephalosporins having a 3-vinyl or substituted 3-vinyl group
US4065620A (en) * 1971-06-14 1977-12-27 Eli Lilly And Company 3-(Substituted) vinyl cephalosporins
US4520022A (en) * 1983-01-28 1985-05-28 Bristol-Myers Company Substituted vinyl cephalosporins
FR2580652B1 (fr) * 1985-04-22 1989-01-06 Bristol Myers Co Acide 7-amino-3-propenylcephalosporanique et ses esters
US4708955A (en) * 1985-06-24 1987-11-24 Bristol-Myers Company 3-(substituted)propenyl-7-aminothiazol-ylcephalosporanic acids and esters thereof
US4874856A (en) * 1985-06-24 1989-10-17 Bristol-Myers Company 3-(substituted)propenyl-7-(aminothiazolylacetamido) ceph-3-em-4-carboxylic acids and esters thereof
US4694079A (en) * 1985-07-29 1987-09-15 Bristol-Myers Company 3-propenyl cephalosporin solvates
US4727070A (en) * 1985-11-25 1988-02-23 Bristol-Myers Company 3-Propenzl cephalosporin isomer separation process and derivative
US4870168A (en) * 1987-02-26 1989-09-26 Bristol-Myers Company 3-Unsaturated alkyl cephems from 3-triflyl cephems
DE3734005A1 (de) * 1987-05-26 1988-12-15 Bayer Ag Substituierte vinylcephalosporine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
US4935508A (en) * 1988-08-23 1990-06-19 Bristol-Myers Company Process for cephem prodrug esters
DE3933934A1 (de) * 1989-10-03 1991-04-11 Bayer Ag Verfahren zur herstellung von 7-amino-3-((z)-1-propen-1-yl)-3-cephem-4-carbonsaeure
US5095012A (en) * 1990-08-23 1992-03-10 Bristol-Myers Squibb Company Antibiotic c-7 catechol-substituted cephalosporin compounds, compositions, and method of use thereof
ES2157199T3 (es) * 1991-03-08 2001-08-16 Biochemie Gmbh Nuevo procedimiento para la produccion de cefalosporinas y nuevos compuestos intermedios para este procedimiento.

Also Published As

Publication number Publication date
DE69232048D1 (de) 2001-10-11
JP2825655B2 (ja) 1998-11-18
US6136967A (en) 2000-10-24
DE69233249T2 (de) 2004-08-19
JPH07503474A (ja) 1995-04-13
CA2124322A1 (en) 1993-08-19
DK0630380T3 (da) 2001-12-10
DE69232048T2 (de) 2002-07-04
KR950700311A (ko) 1995-01-16
ATE205214T1 (de) 2001-09-15
ATE253583T1 (de) 2003-11-15
PT630380E (pt) 2002-02-28
EP1103555B1 (en) 2003-11-05
DE69233249D1 (de) 2003-12-11
CA2124322C (en) 2007-04-17
EP0630380B1 (en) 2001-09-05
ES2162812T3 (es) 2002-01-16
TW230775B (zh) 1994-09-21
EP0630380A1 (en) 1994-12-28
ES2210047T3 (es) 2004-07-01
EP1103555A1 (en) 2001-05-30
GR3036985T3 (en) 2002-01-31
WO1993016084A1 (en) 1993-08-19
US5869648A (en) 1999-02-09
US6333409B1 (en) 2001-12-25

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