SG43951A1 - Use of indole derivatives as 5HT1 antagonists - Google Patents

Use of indole derivatives as 5HT1 antagonists

Info

Publication number: SG43951A1
Authority: SG; Singapore
Prior art keywords: antagonists; indole derivatives; indole; derivatives
Prior art date: 1993-04-27

Application number

SG1996006766A

Other languages

English (en)

Inventor

John Eugene Macor

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-04-27

Filing date

1994-04-26

Publication date

1997-11-14

1994-04-26 Application filed by Pfizer filed Critical Pfizer

1997-11-14 Publication of SG43951A1 publication Critical patent/SG43951A1/en

Links

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, ***e
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Pain & Pain Management (AREA)
Epidemiology (AREA)
Heart & Thoracic Surgery (AREA)
Psychiatry (AREA)
Cardiology (AREA)
Child & Adolescent Psychology (AREA)
Hematology (AREA)
Obesity (AREA)
Diabetes (AREA)
Anesthesiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Indole Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

SG1996006766A 1993-04-27 1994-04-26 Use of indole derivatives as 5HT1 antagonists SG43951A1 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US5393093A	1993-04-27	1993-04-27

Publications (1)

Publication Number	Publication Date
SG43951A1 true SG43951A1 (en)	1997-11-14

Family

ID=21987528

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SG1996006766A SG43951A1 (en)	1993-04-27	1994-04-26	Use of indole derivatives as 5HT1 antagonists

Country Status (29)

Country	Link
EP (1)	EP0696194B1 (no)
JP (1)	JP2922307B2 (no)
KR (1)	KR960701636A (no)
CN (3)	CN1515252A (no)
AP (1)	AP486A (no)
AT (1)	ATE222492T1 (no)
AU (1)	AU689469B2 (no)
BG (1)	BG61898B1 (no)
BR (1)	BR9406435A (no)
CA (1)	CA2161533C (no)
CO (1)	CO4230093A1 (no)
CZ (1)	CZ290416B6 (no)
DE (1)	DE69431201T2 (no)
DK (1)	DK0696194T3 (no)
ES (1)	ES2180573T3 (no)
HU (1)	HU222488B1 (no)
IL (1)	IL109376A (no)
MX (1)	MX9403088A (no)
NO (1)	NO308236B1 (no)
NZ (1)	NZ263614A (no)
OA (1)	OA10189A (no)
PL (1)	PL175156B1 (no)
PT (1)	PT696194E (no)
RO (1)	RO117760B1 (no)
RU (1)	RU2132683C1 (no)
SG (1)	SG43951A1 (no)
SK (1)	SK283353B6 (no)
WO (1)	WO1994025023A1 (no)
ZA (1)	ZA942805B (no)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5559129A (en) *	1990-10-15	1996-09-24	Pfizer Inc	Indole derivatives
US5545644A (en) *	1990-10-15	1996-08-13	Pfizer Inc.	Indole derivatives
US5578612A (en) *	1990-10-15	1996-11-26	Pfizer Inc.	Indole derivatives
US5559246A (en) *	1990-10-15	1996-09-24	Pfizer Inc.	Indole derivatives
US5607951A (en) *	1990-10-15	1997-03-04	Pfizer Inc	Indole derivatives
CA2169179C (en) *	1993-08-31	2000-02-29	John E. Macor	5-arylindole derivatives
GB9417310D0 (en) *	1994-08-27	1994-10-19	Pfizer Ltd	Therapeutic agents
ATE224388T1 (de) *	1994-10-12	2002-10-15	Pfizer Res & Dev	Indolderivate zur behandlung von migräne
GB9424471D0 (en) *	1994-12-03	1995-01-18	Pfizer Ltd	Treatment of emesis
GB9510223D0 (en) *	1995-05-20	1995-07-19	Pfizer Ltd	Therapeutic agent
US5945118A (en) *	1995-09-29	1999-08-31	Pfizer Inc	Indole derivative for the treatment of migraine
US5773015A (en) *	1996-11-27	1998-06-30	Elizabeth Arden Co., Division Of Conopco, Inc.	Method for controlling skin oils and grease
GB9706089D0 (en) *	1997-03-24	1997-05-14	Scherer Ltd R P	Pharmaceutical composition
US5994352A (en) *	1998-11-13	1999-11-30	Pfizer Inc.	5-arylindole derivatives
ES2199086B1 (es) *	2002-07-31	2005-06-01	Cepa Schwarz Pharma Sl	Nuevos derivados de cicloalcanodionas, procedimiento para su preparacion y sus aplicaciones farmacologicas.
CA3166940A1 (en) *	2020-02-04	2021-08-12	Abdelmalik Slassi	3-pyrrolidine-indole derivatives as serotonergic psychedelic agents for the treatment of cns disorders

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BR9106978A (pt) *	1990-10-15	1993-09-28	Pfizer	Derivados de indol
GB9102579D0 (en) *	1991-01-24	1991-03-27	Glaxo Group Ltd	Compositions
GB9103770D0 (en) *	1991-02-22	1991-04-10	Glaxo Group Ltd	Chemical compounds

1994
- 1994-04-07 AP APAP/P/1994/000633A patent/AP486A/en active
- 1994-04-21 IL IL10937694A patent/IL109376A/xx not_active IP Right Cessation
- 1994-04-22 ZA ZA942805A patent/ZA942805B/xx unknown
- 1994-04-25 CO CO94016790A patent/CO4230093A1/es unknown
- 1994-04-26 PL PL94311266A patent/PL175156B1/pl unknown
- 1994-04-26 HU HU9503089A patent/HU222488B1/hu not_active IP Right Cessation
- 1994-04-26 PT PT94912048T patent/PT696194E/pt unknown
- 1994-04-26 EP EP94912048A patent/EP0696194B1/en not_active Expired - Lifetime
- 1994-04-26 ES ES94912048T patent/ES2180573T3/es not_active Expired - Lifetime
- 1994-04-26 NZ NZ263614A patent/NZ263614A/en unknown
- 1994-04-26 DE DE69431201T patent/DE69431201T2/de not_active Expired - Fee Related
- 1994-04-26 DK DK94912048T patent/DK0696194T3/da active
- 1994-04-26 CA CA002161533A patent/CA2161533C/en not_active Expired - Fee Related
- 1994-04-26 JP JP6524076A patent/JP2922307B2/ja not_active Expired - Fee Related
- 1994-04-26 AU AU64360/94A patent/AU689469B2/en not_active Ceased
- 1994-04-26 SG SG1996006766A patent/SG43951A1/en unknown
- 1994-04-26 RO RO95-01860A patent/RO117760B1/ro unknown
- 1994-04-26 KR KR1019950704678A patent/KR960701636A/ko not_active Application Discontinuation
- 1994-04-26 RU RU95120093/14A patent/RU2132683C1/ru not_active IP Right Cessation
- 1994-04-26 WO PCT/IB1994/000079 patent/WO1994025023A1/en active IP Right Grant
- 1994-04-26 CN CNA021506892A patent/CN1515252A/zh active Pending
- 1994-04-26 CZ CZ19952802A patent/CZ290416B6/cs not_active IP Right Cessation
- 1994-04-26 CN CN94191935A patent/CN1121689A/zh active Pending
- 1994-04-26 AT AT94912048T patent/ATE222492T1/de not_active IP Right Cessation
- 1994-04-26 CN CNA011046600A patent/CN1509713A/zh active Pending
- 1994-04-26 BR BR9406435A patent/BR9406435A/pt not_active Application Discontinuation
- 1994-04-26 SK SK1332-95A patent/SK283353B6/sk unknown
- 1994-04-27 MX MX9403088A patent/MX9403088A/es unknown
1995
- 1995-10-25 BG BG100093A patent/BG61898B1/bg unknown
- 1995-10-26 NO NO954287A patent/NO308236B1/no not_active IP Right Cessation
- 1995-10-27 OA OA60728A patent/OA10189A/en unknown

Also Published As

Publication number	Publication date
CZ290416B6 (cs)	2002-07-17
DK0696194T3 (da)	2002-10-07
CA2161533A1 (en)	1994-11-10
HU9503089D0 (en)	1995-12-28
EP0696194A1 (en)	1996-02-14
CN1515252A (zh)	2004-07-28
DE69431201D1 (de)	2002-09-26
ATE222492T1 (de)	2002-09-15
ES2180573T3 (es)	2003-02-16
NZ263614A (en)	1998-02-26
SK283353B6 (sk)	2003-06-03
WO1994025023A1 (en)	1994-11-10
HU222488B1 (hu)	2003-07-28
CN1509713A (zh)	2004-07-07
RO117760B1 (ro)	2002-07-30
JPH08504829A (ja)	1996-05-28
NO308236B1 (no)	2000-08-21
RU2132683C1 (ru)	1999-07-10
BG100093A (bg)	1996-04-30
OA10189A (en)	1996-12-18
BR9406435A (pt)	1996-01-09
IL109376A0 (en)	1994-07-31
EP0696194B1 (en)	2002-08-21
PL311266A1 (en)	1996-02-05
NO954287L (no)	1995-10-26
CO4230093A1 (es)	1995-10-19
AP486A (en)	1996-04-16
KR960701636A (ko)	1996-03-28
PT696194E (pt)	2002-11-29
AP9400633A0 (en)	1994-04-30
CZ9502802A3 (en)	1996-04-17
CN1121689A (zh)	1996-05-01
CA2161533C (en)	1998-08-04
DE69431201T2 (de)	2002-12-05
BG61898B1 (bg)	1998-09-30
PL175156B1 (pl)	1998-11-30
IL109376A (en)	2000-10-31
SK133295A3 (en)	1997-01-08
MX9403088A (es)	1997-02-28
AU6436094A (en)	1994-11-21
ZA942805B (en)	1995-10-23
JP2922307B2 (ja)	1999-07-19
HUT73670A (en)	1996-09-30
NO954287D0 (no)	1995-10-26
AU689469B2 (en)	1998-04-02

Publication	Publication Date	Title
HU9402601D0 (en)	1994-12-28	Condensed indole derivatives as 5ht4-receptor antagonists
HK1014669A1 (en)	1999-09-30	Use of tetrahydrocarbazole derivatives as 5ht1-receptor agonists
EP0442878A4 (en)	1991-10-23	Derivatives of tryptophan as cck antagonists
EP0707581A1 (en)	1996-04-24	INDOLINE DERIVATIVES AS 5 HT2C ANTAGONISTS
SI1475377T1 (sl)	2006-12-31	Indolni derivati in njihova uporaba kot inhibitorji fosfodiesteraze 4
GR3036881T3 (en)	2002-01-31	Benzamide derivatives and their use as vasopressin antagonists
PL329725A1 (en)	1999-04-12	Indole derivatives useful as antagonists of endotelin receptor
ZA942383B (en)	1995-10-09	New indole derivatives
HUT73670A (en)	1996-09-30	Use of indole derivatives as 5ht1 antagonists
HU9600969D0 (en)	1996-06-28	Indole derivatives as nmda antagonists
AU6435594A (en)	1994-11-08	Indole derivatives as dopamine d4 antagonists
AU4261293A (en)	1993-11-29	1-piperazineacetic derivatives as fibrinogen receptor antagonists
AU6215594A (en)	1994-10-11	Indole derivatives as dopamine d4 antagonists
ZA955753B (en)	1997-01-11	Heterocyclic derivatives of azolones
PL330708A1 (en)	1999-05-24	Derivatives of indolydine useful as antagonists of 5-ht-2c receptor
LV10448A (lv)	1995-02-20	Piperazinilkamparsulfoniloksitocina antagonista aizvietotie amidu atvasinajumi
AU3440693A (en)	1993-08-03	Substituted 1-isoquinolone derivatives as angiotensin II antagonists
AU7186994A (en)	1995-01-17	Phenyrrole derivatives and their use as dopamine d3 antagonists
HK1066804A1 (en)	2005-04-01	Derivatives of indole and their use as phosphodiesterase 4 inhibitors
AU4712696A (en)	1996-09-04	The use of heterocyclic compounds
AU6215794A (en)	1994-10-11	Indole derivatives as dopamine d4 antagonists
GB9320940D0 (en)	1993-12-01	Substituted n-carboxyalkylpeptidyl derivatives as antidegenerative agents
FI953361A (fi)	1995-07-07	Menetelmä substituoitujen indolonijohdannaisten valmistamiseksi
AU1809595A (en)	1995-09-04	Phenylpyrrole derivatives and their use as dopamine d3 antagonists
AU7460194A (en)	1995-02-28	2-phenylpyrrole derivatives as dopamine d3 receptor antagonists