AU4261293A - 1-piperazineacetic derivatives as fibrinogen receptor antagonists - Google Patents
1-piperazineacetic derivatives as fibrinogen receptor antagonistsInfo
- Publication number
- AU4261293A AU4261293A AU42612/93A AU4261293A AU4261293A AU 4261293 A AU4261293 A AU 4261293A AU 42612/93 A AU42612/93 A AU 42612/93A AU 4261293 A AU4261293 A AU 4261293A AU 4261293 A AU4261293 A AU 4261293A
- Authority
- AU
- Australia
- Prior art keywords
- piperazineacetic
- derivatives
- receptor antagonists
- fibrinogen receptor
- fibrinogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9208740 | 1992-04-23 | ||
GB929208740A GB9208740D0 (en) | 1992-04-23 | 1992-04-23 | Chemical compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
AU4261293A true AU4261293A (en) | 1993-11-29 |
Family
ID=10714405
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU42612/93A Abandoned AU4261293A (en) | 1992-04-23 | 1993-04-20 | 1-piperazineacetic derivatives as fibrinogen receptor antagonists |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP0637304A1 (en) |
JP (1) | JPH07505897A (en) |
CN (1) | CN1083475A (en) |
AU (1) | AU4261293A (en) |
GB (1) | GB9208740D0 (en) |
IL (1) | IL105375A0 (en) |
MX (1) | MX9302283A (en) |
WO (1) | WO1993022303A1 (en) |
ZA (1) | ZA932790B (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU668765B2 (en) * | 1992-10-12 | 1996-05-16 | Dr. Karl Thomae Gmbh | Carboxylic acid derivatives |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5750754A (en) * | 1993-03-29 | 1998-05-12 | Zeneca Limited | Heterocyclic compounds |
DK0691959T3 (en) * | 1993-03-29 | 1999-04-26 | Zeneca Ltd | Heterocyclic derivatives as platelet aggregation inhibitors |
ZW4194A1 (en) * | 1993-03-29 | 1994-12-21 | Zeneca Ltd | Heterocyclic compounds |
US5652242A (en) * | 1993-03-29 | 1997-07-29 | Zeneca Limited | Heterocyclic derivatives |
US5753659A (en) * | 1993-03-29 | 1998-05-19 | Zeneca Limited | Heterocyclic compouds |
US5463011A (en) * | 1993-06-28 | 1995-10-31 | Zeneca Limited | Acid derivatives |
GB9313268D0 (en) * | 1993-06-28 | 1993-08-11 | Zeneca Ltd | Chemical compounds |
GB9313285D0 (en) * | 1993-06-28 | 1993-08-11 | Zeneca Ltd | Acid derivatives |
GB9326373D0 (en) * | 1993-12-23 | 1994-02-23 | Zeneca Ltd | Chemical compounds |
GB9326232D0 (en) * | 1993-12-23 | 1994-02-23 | Zeneca Ltd | Chemical compounds |
USRE39263E1 (en) * | 1994-05-04 | 2006-09-05 | Bayer Aktiengesellschaft | Substituted aromatic thiocarboxylic acid amides and their use as herbicides |
WO1995030661A1 (en) | 1994-05-04 | 1995-11-16 | Bayer Aktiengesellschaft | Substituted aromatic thiocarboxylic acid amides and their use as herbicides |
AR008245A1 (en) * | 1996-06-21 | 1999-12-29 | Glaxo Group Ltd | DERIVATIVES OF ACETIC ACID, USE OF THE SAME IN THE MANUFACTURE OF A THERAPEUTIC AGENT AND PROCESS TO PREPARE SUCH DERIVATIVES |
AU3261097A (en) * | 1996-06-21 | 1998-01-14 | Glaxo Group Limited | Piperidine acetic acid derivatives and their use in the treatment of thrombotic disorders |
DE19743435A1 (en) * | 1997-10-01 | 1999-04-08 | Merck Patent Gmbh | Benzamidine derivatives |
US7361773B2 (en) | 2002-03-12 | 2008-04-22 | Wyeth | Preparation of N1-(2'-pyridyl)-1,2-propanediamine sulfamic acid and its use in the synthesis of biologically active piperazines |
NZ535169A (en) * | 2002-03-12 | 2006-03-31 | Wyeth Corp | Process for making chiral 1,4-disubstituted piperazines |
WO2004032933A1 (en) * | 2002-10-11 | 2004-04-22 | Kowa Co., Ltd. | Method for treatment of cancer |
EP1968961A2 (en) | 2005-12-21 | 2008-09-17 | Decode Genetics EHF | Biaryl nitrogen heterocycle inhibitors of lta4h for treating inflammation |
CA3224732A1 (en) | 2021-07-07 | 2023-01-12 | Kevin M. Guckian | Compounds for targeting degradation of irak4 proteins |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5084466A (en) * | 1989-01-31 | 1992-01-28 | Hoffmann-La Roche Inc. | Novel carboxamide pyridine compounds which have useful pharmaceutical utility |
-
1992
- 1992-04-23 GB GB929208740A patent/GB9208740D0/en active Pending
-
1993
- 1993-04-14 IL IL105375A patent/IL105375A0/en unknown
- 1993-04-20 AU AU42612/93A patent/AU4261293A/en not_active Abandoned
- 1993-04-20 WO PCT/EP1993/000963 patent/WO1993022303A1/en not_active Application Discontinuation
- 1993-04-20 JP JP5518882A patent/JPH07505897A/en active Pending
- 1993-04-20 EP EP93911769A patent/EP0637304A1/en not_active Withdrawn
- 1993-04-20 MX MX9302283A patent/MX9302283A/en unknown
- 1993-04-21 ZA ZA932790A patent/ZA932790B/en unknown
- 1993-04-22 CN CN93105910A patent/CN1083475A/en active Pending
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU668765B2 (en) * | 1992-10-12 | 1996-05-16 | Dr. Karl Thomae Gmbh | Carboxylic acid derivatives |
Also Published As
Publication number | Publication date |
---|---|
CN1083475A (en) | 1994-03-09 |
MX9302283A (en) | 1994-02-28 |
JPH07505897A (en) | 1995-06-29 |
WO1993022303A1 (en) | 1993-11-11 |
EP0637304A1 (en) | 1995-02-08 |
GB9208740D0 (en) | 1992-06-10 |
ZA932790B (en) | 1994-03-25 |
IL105375A0 (en) | 1993-08-18 |
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