SG136958A1 - Antagonistic analogs of gh-rh (2003) - Google Patents

Antagonistic analogs of gh-rh (2003)

Info

Publication number
SG136958A1
SG136958A1 SG200716961-8A SG2007169618A SG136958A1 SG 136958 A1 SG136958 A1 SG 136958A1 SG 2007169618 A SG2007169618 A SG 2007169618A SG 136958 A1 SG136958 A1 SG 136958A1
Authority
SG
Singapore
Prior art keywords
antagonistic analogs
antagonistic
analogs
Prior art date
Application number
SG200716961-8A
Other languages
English (en)
Inventor
Andrew V Schally
Jozsef Varga
Marta Zarandi
Ren Zhi Cai
Original Assignee
Univ Tulane
Us Health
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Tulane, Us Health filed Critical Univ Tulane
Publication of SG136958A1 publication Critical patent/SG136958A1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/60Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/06Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Analytical Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
SG200716961-8A 2003-08-05 2004-07-26 Antagonistic analogs of gh-rh (2003) SG136958A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US49270603P 2003-08-05 2003-08-05

Publications (1)

Publication Number Publication Date
SG136958A1 true SG136958A1 (en) 2007-11-29

Family

ID=34193144

Family Applications (1)

Application Number Title Priority Date Filing Date
SG200716961-8A SG136958A1 (en) 2003-08-05 2004-07-26 Antagonistic analogs of gh-rh (2003)

Country Status (19)

Country Link
US (1) US7452865B2 (ru)
EP (1) EP1651662A4 (ru)
JP (1) JP2007526900A (ru)
KR (1) KR20060088875A (ru)
CN (1) CN1871020A (ru)
AR (1) AR049149A1 (ru)
AU (1) AU2004265280A1 (ru)
BR (1) BRPI0413257A (ru)
CA (1) CA2534436A1 (ru)
IL (1) IL173201A0 (ru)
MX (1) MXPA06001369A (ru)
NO (1) NO20061060L (ru)
PL (1) PL380437A1 (ru)
RS (1) RS20060086A (ru)
RU (1) RU2335506C2 (ru)
SG (1) SG136958A1 (ru)
TW (1) TW200517400A (ru)
WO (1) WO2005016953A2 (ru)
ZA (1) ZA200600966B (ru)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009108364A2 (en) * 2008-02-27 2009-09-03 Ipsen Pharma S.A.S. Antagonistic analogues of ghrh
AU2009228244A1 (en) * 2008-03-28 2009-10-01 The United States Of America Represented By The United States Department Of Veteran's Affairs Novel N-and C-terminal substituted -antagonistic analogs of human GH-RH
US8691942B2 (en) 2008-03-28 2014-04-08 University Of Miami N- and C- terminal substituted antagonistic analogs of GH-RH
EP2310028B1 (en) * 2008-06-12 2016-11-16 Ipsen Bioinnovation Limited Fusion proteins for use in the treatment of acromegaly
US8796216B2 (en) 2008-06-12 2014-08-05 Syntaxin Limited Suppression of neuroendocrine diseases
CN107446053A (zh) 2008-06-12 2017-12-08 益普生生物创新有限公司 癌症的抑制
US8227421B2 (en) * 2009-09-17 2012-07-24 University Of Miami Fluorinated GHRH antagonists
WO2011153491A2 (en) 2010-06-03 2011-12-08 University Of Miami Agonists of growth hormone releasing hormone as effectors for survival and proliferation of pancreatic islets
US8361964B2 (en) 2011-04-21 2013-01-29 Theratechnologies Inc. Growth hormone releasing factor (GRF) analogs and uses thereof
US9079974B2 (en) * 2011-12-21 2015-07-14 The University Of Miami GH-RH analogs with potent agonistic effects
US20150166617A1 (en) * 2012-06-27 2015-06-18 University Of Miami Compositions and methods of treating alzheimer's disease
WO2014100816A2 (en) 2012-12-21 2014-06-26 University Of Miami Ghrh agonists for islet cell transplantation and function and the treatment of diabetes
US9855312B2 (en) 2012-12-21 2018-01-02 University Of Miami GHRH agonists for the treatment of ischemic disorders
EP3920961A4 (en) 2019-02-08 2022-12-14 United States Government as represented by the Department of Veterans Affairs GROWTH HORMONE RELEASING HORMONE ANTAGONISTS AND THEIR USES
CA3178840A1 (en) 2020-04-27 2021-11-04 The University Of Miami Method of treating an inflammatory disorder
CN114195881B (zh) * 2021-12-16 2022-09-16 浙江湃肽生物股份有限公司 一种制备醋酸舍莫瑞林的方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5942489A (en) * 1996-05-03 1999-08-24 The Administrators Of The Tulane Educational Fund HGH-RH(1-29)NH2 analogues having antagonistic activity
US6057422A (en) * 1998-11-25 2000-05-02 The Administrators Of The Tulane Educational Fund Antagonistic analogs of GH-RH inhibiting IGF-I and -II

Also Published As

Publication number Publication date
KR20060088875A (ko) 2006-08-07
IL173201A0 (en) 2006-06-11
EP1651662A4 (en) 2009-07-01
JP2007526900A (ja) 2007-09-20
US20070042950A1 (en) 2007-02-22
NO20061060L (no) 2006-05-03
US7452865B2 (en) 2008-11-18
WO2005016953A3 (en) 2006-02-09
ZA200600966B (en) 2007-05-30
RU2335506C2 (ru) 2008-10-10
RS20060086A (en) 2008-08-07
BRPI0413257A (pt) 2006-10-03
AR049149A1 (es) 2006-07-05
MXPA06001369A (es) 2007-02-19
EP1651662A2 (en) 2006-05-03
RU2006106701A (ru) 2007-09-20
TW200517400A (en) 2005-06-01
PL380437A1 (pl) 2007-01-22
AU2004265280A1 (en) 2005-02-24
WO2005016953A2 (en) 2005-02-24
CN1871020A (zh) 2006-11-29
CA2534436A1 (en) 2005-02-24

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