SG11201909697TA - Optimal index sequences for multiplex massively parallel sequencing - Google Patents
Optimal index sequences for multiplex massively parallel sequencingInfo
- Publication number
- SG11201909697TA SG11201909697TA SG11201909697TA SG11201909697TA SG 11201909697T A SG11201909697T A SG 11201909697TA SG 11201909697T A SG11201909697T A SG 11201909697TA SG 11201909697T A SG11201909697T A SG 11201909697TA
- Authority
- SG
- Singapore
- Prior art keywords
- index
- sequences
- international
- california
- color
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
- G16B30/10—Sequence alignment; Homology search
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
- C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1065—Preparation or screening of tagged libraries, e.g. tagged microorganisms by STM-mutagenesis, tagged polynucleotides, gene tags
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6811—Selection methods for production or design of target specific oligonucleotides or binding molecules
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/06—Libraries containing nucleotides or polynucleotides, or derivatives thereof
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Biomedical Technology (AREA)
- Evolutionary Biology (AREA)
- Medical Informatics (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Theoretical Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Plant Pathology (AREA)
- Crystallography & Structural Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762492851P | 2017-05-01 | 2017-05-01 | |
| US201762524390P | 2017-06-23 | 2017-06-23 | |
| PCT/US2018/030539 WO2018204423A1 (fr) | 2017-05-01 | 2018-05-01 | Séquences index optimales pour séquençage multiplex massivement parallèle |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201909697TA true SG11201909697TA (en) | 2019-11-28 |
Family
ID=62200563
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201909697T SG11201909697TA (en) | 2017-05-01 | 2018-05-01 | Optimal index sequences for multiplex massively parallel sequencing |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US11028435B2 (fr) |
| EP (1) | EP3619326A1 (fr) |
| CN (1) | CN110799653A (fr) |
| AU (1) | AU2018261332A1 (fr) |
| CA (2) | CA3220983A1 (fr) |
| SG (1) | SG11201909697TA (fr) |
| WO (1) | WO2018204423A1 (fr) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110799653A (zh) * | 2017-05-01 | 2020-02-14 | 伊鲁米那股份有限公司 | 用于多重大规模平行测序的最佳索引序列 |
| SG11201910070PA (en) | 2017-05-08 | 2019-11-28 | Illumina Inc | Universal short adapters for indexing of polynucleotide samples |
| EP3696275A4 (fr) * | 2017-10-11 | 2021-05-26 | MGI Tech Co., Ltd. | Procédé d'amélioration du chargement et de la stabilité d'acide nucléique sur un support solide |
| US11210554B2 (en) | 2019-03-21 | 2021-12-28 | Illumina, Inc. | Artificial intelligence-based generation of sequencing metadata |
| US11347965B2 (en) | 2019-03-21 | 2022-05-31 | Illumina, Inc. | Training data generation for artificial intelligence-based sequencing |
| US11593649B2 (en) | 2019-05-16 | 2023-02-28 | Illumina, Inc. | Base calling using convolutions |
| US20210054451A1 (en) * | 2019-08-19 | 2021-02-25 | Inscripta, Inc. | Optimizing high-throughput sequencing capacity |
| CN110468188B (zh) * | 2019-08-22 | 2023-08-22 | 广州微远医疗器械有限公司 | 用于二代测序的标签序列集及其设计方法和应用 |
| CA3142535A1 (fr) | 2019-09-20 | 2021-03-25 | Illumina, Inc. | Procedes et compositions pour identifier des ligands sur des reseaux a l'aide d'indices et de codes a barres |
| GB2589869A (en) * | 2019-12-09 | 2021-06-16 | Univ Oxford Innovation Ltd | Method for whole genome sequencing of picogram quantities of DNA |
| EP3836148A1 (fr) | 2019-12-09 | 2021-06-16 | Lexogen GmbH | Séquences d'indice de séquençage parallèle de multiplexage |
| BR112022016415A2 (pt) | 2020-02-20 | 2022-10-11 | Illumina Inc | Múltiplas chamadas de base à base de inteligência artificial |
| US20210265009A1 (en) | 2020-02-20 | 2021-08-26 | Illumina, Inc. | Artificial Intelligence-Based Base Calling of Index Sequences |
| CN111326210B (zh) * | 2020-03-11 | 2023-07-14 | 中国科学院生态环境研究中心 | 一种基于k-mer算法的引物设计方法及*** |
| WO2021252617A1 (fr) * | 2020-06-09 | 2021-12-16 | Illumina, Inc. | Procédés pour augmenter le rendement de bibliothèques de séquençage |
| KR20230069135A (ko) | 2020-09-11 | 2023-05-18 | 일루미나 케임브리지 리미티드 | 헤어핀 어댑터를 사용하여 시퀀싱 라이브러리에서 표적 서열을 농축시키는 방법 |
| IL302207A (en) | 2020-10-21 | 2023-06-01 | Illumina Inc | Sequencing templates that include several additions and compositions and methods to improve sequencing output |
| CA3182960A1 (fr) * | 2020-11-06 | 2022-05-12 | Illumina, Inc. | Detection de substances dans un melange a l'aide d'oligonucleotides |
| CA3214282A1 (fr) | 2021-03-29 | 2022-10-06 | Illumina, Inc. | Compositions et procedes pour evaluer l'endommagement de l'adn dans une bibliotheque et normaliser une polarisation de taille d'amplicon |
| MX2023010495A (es) | 2021-03-30 | 2023-09-18 | Illumina Inc | Metodos mejorados de preparacion de genoteca y adn complementarios isotermicos. |
| MX2023011218A (es) | 2021-03-31 | 2023-10-02 | Illumina Inc | Métodos de preparación de genotecas de secuenciación de tagmentación direccional usando tecnología basada en transposón con identificadores moleculares únicos para la corrección de errores. |
| US20220336054A1 (en) | 2021-04-15 | 2022-10-20 | Illumina, Inc. | Deep Convolutional Neural Networks to Predict Variant Pathogenicity using Three-Dimensional (3D) Protein Structures |
| EP4313911A1 (fr) * | 2021-04-30 | 2024-02-07 | Quantum-si Incorporated | Adaptateur universel pour séquençage |
| US20230005253A1 (en) | 2021-07-01 | 2023-01-05 | Illumina, Inc. | Efficient artificial intelligence-based base calling of index sequences |
| WO2023287876A1 (fr) * | 2021-07-15 | 2023-01-19 | University Of Washington | Séquençage duplex efficace utilisant des lectures de séquençage de nouvelle génération à haute fidélité |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| EP0450060A1 (fr) | 1989-10-26 | 1991-10-09 | Sri International | Sequen age d'adn |
| US5677170A (en) | 1994-03-02 | 1997-10-14 | The Johns Hopkins University | In vitro transposition of artificial transposons |
| DE69837913T2 (de) | 1997-04-01 | 2008-02-07 | Solexa Ltd., Saffron Walden | Verfahren zur vervielfältigung von nukleinsäure |
| US6159736A (en) | 1998-09-23 | 2000-12-12 | Wisconsin Alumni Research Foundation | Method for making insertional mutations using a Tn5 synaptic complex |
| AR021833A1 (es) | 1998-09-30 | 2002-08-07 | Applied Research Systems | Metodos de amplificacion y secuenciacion de acido nucleico |
| WO2002004680A2 (fr) | 2000-07-07 | 2002-01-17 | Visigen Biotechnologies, Inc. | Determination de sequence en temps reel |
| AU2002227156A1 (en) | 2000-12-01 | 2002-06-11 | Visigen Biotechnologies, Inc. | Enzymatic nucleic acid synthesis: compositions and methods for altering monomer incorporation fidelity |
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| JP2007525571A (ja) | 2004-01-07 | 2007-09-06 | ソレクサ リミテッド | 修飾分子アレイ |
| JP2008513782A (ja) | 2004-09-17 | 2008-05-01 | パシフィック バイオサイエンシーズ オブ カリフォルニア， インコーポレイテッド | 分子解析のための装置及び方法 |
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| CN105132407B (zh) * | 2015-08-10 | 2017-12-12 | 北京吉因加科技有限公司 | 一种脱落细胞dna低频突变富集测序方法 |
| CN105063208B (zh) * | 2015-08-10 | 2018-03-06 | 北京吉因加科技有限公司 | 一种血浆中游离的目标dna低频突变富集测序方法 |
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| CN110520542B (zh) | 2017-03-23 | 2024-06-14 | 华盛顿大学 | 用于靶向核酸序列富集的方法及在错误纠正的核酸测序中的应用 |
| CN110799653A (zh) | 2017-05-01 | 2020-02-14 | 伊鲁米那股份有限公司 | 用于多重大规模平行测序的最佳索引序列 |
| SG11201910070PA (en) | 2017-05-08 | 2019-11-28 | Illumina Inc | Universal short adapters for indexing of polynucleotide samples |
| US11739367B2 (en) | 2017-11-08 | 2023-08-29 | Twinstrand Biosciences, Inc. | Reagents and adapters for nucleic acid sequencing and methods for making such reagents and adapters |
| SG11202007648WA (en) | 2018-02-13 | 2020-09-29 | Twinstrand Biosciences Inc | Methods and reagents for detecting and assessing genotoxicity |
| EP3765063A4 (fr) | 2018-03-15 | 2021-12-15 | Twinstrand Biosciences, Inc. | Procédés et réactifs pour l'enrichissement de matériau d'acide nucléique pour des applications de séquençage et d'autres interrogations de matériau d'acide nucléique |
| AU2019269635A1 (en) | 2018-05-16 | 2020-11-26 | Twinstrand Biosciences, Inc. | Methods and reagents for resolving nucleic acid mixtures and mixed cell populations and associated applications |
| BR112021000409A2 (pt) | 2018-07-12 | 2021-04-06 | Twinstrand Biosciences, Inc. | Métodos e reagentes para caracterizar edição genômica, expansão clonal e aplicações associadas |
| JP2022505050A (ja) | 2018-10-16 | 2022-01-14 | ツインストランド・バイオサイエンシズ・インコーポレイテッド | プーリングを介した多数の試料の効率的な遺伝子型決定のための方法および試薬 |
| AU2020321991A1 (en) | 2019-08-01 | 2022-03-03 | Twinstrand Biosciences, Inc. | Methods and reagents for nucleic acid sequencing and associated applications |
-
2018
- 2018-05-01 CN CN201880042029.2A patent/CN110799653A/zh active Pending
- 2018-05-01 CA CA3220983A patent/CA3220983A1/fr active Pending
- 2018-05-01 AU AU2018261332A patent/AU2018261332A1/en active Pending
- 2018-05-01 EP EP18726000.5A patent/EP3619326A1/fr active Pending
- 2018-05-01 US US15/968,613 patent/US11028435B2/en active Active
- 2018-05-01 SG SG11201909697T patent/SG11201909697TA/en unknown
- 2018-05-01 WO PCT/US2018/030539 patent/WO2018204423A1/fr unknown
- 2018-05-01 CA CA3060369A patent/CA3060369A1/fr active Pending
-
2021
- 2021-05-04 US US17/307,959 patent/US11788139B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| WO2018204423A1 (fr) | 2018-11-08 |
| US11028435B2 (en) | 2021-06-08 |
| CA3220983A1 (fr) | 2018-11-08 |
| CN110799653A (zh) | 2020-02-14 |
| US20180334711A1 (en) | 2018-11-22 |
| US20210254154A1 (en) | 2021-08-19 |
| CA3060369A1 (fr) | 2018-11-08 |
| EP3619326A1 (fr) | 2020-03-11 |
| AU2018261332A1 (en) | 2019-11-07 |
| US11788139B2 (en) | 2023-10-17 |
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