SG11201706511TA - Benzoxaborole compounds and uses thereof - Google Patents

Benzoxaborole compounds and uses thereof

Info

Publication number
SG11201706511TA
SG11201706511TA SG11201706511TA SG11201706511TA SG11201706511TA SG 11201706511T A SG11201706511T A SG 11201706511TA SG 11201706511T A SG11201706511T A SG 11201706511TA SG 11201706511T A SG11201706511T A SG 11201706511TA SG 11201706511T A SG11201706511T A SG 11201706511TA
Authority
SG
Singapore
Prior art keywords
benzoxaborole compounds
benzoxaborole
compounds
Prior art date
Application number
SG11201706511TA
Other languages
English (en)
Inventor
M R K Alley (Dickon)
David Barros-Aguirre
Ilaria Giordano
Vincent Hernandez
Xianfeng Li
Jacob J Plattner
Original Assignee
Glaxosmithkline Intellectual Property (No 2) Ltd
Anacor Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=55409879&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG11201706511T(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Glaxosmithkline Intellectual Property (No 2) Ltd, Anacor Pharmaceuticals Inc filed Critical Glaxosmithkline Intellectual Property (No 2) Ltd
Publication of SG11201706511TA publication Critical patent/SG11201706511TA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02Boron compounds
    • C07F5/025Boronic and borinic acid compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/69Boron compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/14Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • A61P31/06Antibacterial agents for tuberculosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • A61P31/08Antibacterial agents for leprosy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02Boron compounds
    • C07F5/04Esters of boric acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Virology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Reproductive Health (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Endocrinology (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SG11201706511TA 2015-02-12 2016-02-12 Benzoxaborole compounds and uses thereof SG11201706511TA (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP15382056 2015-02-12
EP15382055 2015-02-12
EP15382054 2015-02-12
PCT/IB2016/050776 WO2016128949A1 (en) 2015-02-12 2016-02-12 Benzoxaborole compounds and uses thereof

Publications (1)

Publication Number Publication Date
SG11201706511TA true SG11201706511TA (en) 2017-09-28

Family

ID=55409879

Family Applications (2)

Application Number Title Priority Date Filing Date
SG11201706511TA SG11201706511TA (en) 2015-02-12 2016-02-12 Benzoxaborole compounds and uses thereof
SG11201706510YA SG11201706510YA (en) 2015-02-12 2016-02-12 4 -substituted benzoxaborole compounds and uses thereof

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG11201706510YA SG11201706510YA (en) 2015-02-12 2016-02-12 4 -substituted benzoxaborole compounds and uses thereof

Country Status (35)

Country Link
US (3) US10774096B2 (zh)
EP (2) EP3256479B1 (zh)
JP (2) JP2018506540A (zh)
KR (2) KR20170117158A (zh)
CN (2) CN107531730B (zh)
AU (3) AU2016217507B2 (zh)
BR (2) BR112017017213A2 (zh)
CA (2) CA2976030C (zh)
CL (2) CL2017002060A1 (zh)
CO (2) CO2017008816A2 (zh)
CR (2) CR20170371A (zh)
CY (1) CY1123687T1 (zh)
DK (1) DK3256479T3 (zh)
DO (2) DOP2017000189A (zh)
EA (2) EA036516B1 (zh)
ES (1) ES2821951T3 (zh)
HR (1) HRP20201597T1 (zh)
HU (1) HUE051113T2 (zh)
IL (2) IL253865A0 (zh)
LT (1) LT3256479T (zh)
MA (2) MA41494B1 (zh)
MX (2) MX2017010413A (zh)
MY (1) MY194004A (zh)
NZ (1) NZ734379A (zh)
PE (2) PE20171348A1 (zh)
PH (2) PH12017501427A1 (zh)
PL (1) PL3256479T3 (zh)
PT (1) PT3256479T (zh)
RS (1) RS60885B1 (zh)
SG (2) SG11201706511TA (zh)
SI (1) SI3256479T1 (zh)
TW (2) TWI730953B (zh)
UA (1) UA120527C2 (zh)
WO (2) WO2016128949A1 (zh)
ZA (1) ZA201705456B (zh)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6499175B2 (ja) * 2013-08-09 2019-04-10 グラクソスミスクライン、インテレクチュアル、プロパティー、(ナンバー2)、リミテッドGlaxosmithkline Intellectual Property (No.2) Limited 三環式ベンゾキサボロール化合物及びその使用
HRP20221212T1 (hr) 2017-05-08 2022-12-09 Glaxosmithkline Intellectual Property Development Limited Sanfetrinem ili njegova sol ili esteri za uporabu u liječenju mikobakterijskih infekcija
WO2019108982A1 (en) 2017-11-30 2019-06-06 Boragen, Inc. Benzoxaborole compounds and formulations thereof
CA3148168A1 (en) 2018-08-18 2020-02-27 Chun Yu Liu Solid forms of substituted benzoxaborole and compositions thereof
CN110441344B (zh) * 2019-06-25 2020-09-29 北京大学 一种基于固体核磁共振技术检测rna结构的方法
WO2023246841A1 (en) * 2022-06-23 2023-12-28 Shanghai Micurx Pharmaceutical Co., Ltd. Methods and uses of boron compounds in the treatment of nontuberculous mycobacterium infections and pharmaceutical compositions for treatment of same
AU2023287063A1 (en) * 2022-06-23 2024-05-30 Shanghai Micurx Pharmaceutical Co., Ltd. Prodrugs of boron compounds and their use in treating bacterial infections

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9411587D0 (en) * 1994-06-09 1994-08-03 Zeneca Ltd Compound, composition and use
AU4967997A (en) 1996-12-02 1998-06-29 Chisso Corporation Optically active nitro alcohol derivatives, optically active amino alcohol derivates, and process for preparing the same
CA2507908A1 (en) 2002-12-02 2004-06-17 Solvias Ag Catalytic hydrogeneration of carbon-heteroatom double bonds
PL2987796T3 (pl) 2005-02-16 2018-12-31 Anacor Pharmaceuticals, Inc. Fluorowco-podstawione boronoftalidy do leczenia zakażeń
EP1856113B1 (en) 2005-03-08 2016-01-06 Agency for Science, Technology and Research Chiral bisoxazoline catalysts
RU2008131324A (ru) 2005-12-30 2010-02-10 Анакор Фармасьютикалз, Инк. (Us) Борсодержащие малые молекулы
TWM325238U (en) * 2006-12-29 2008-01-11 Universal Scient Ind Co Ltd Voltage regulator and voltage regulating system
KR100848491B1 (ko) 2007-01-16 2008-07-28 영진약품공업주식회사 베타아미노기를 갖는 2-싸이아졸리딘 유도체, 이의약학적으로 허용 가능한 염 및 이의 제조 방법
JO3396B1 (ar) 2007-06-20 2019-10-20 Anacor Pharmaceuticals Inc جزيئات صغيرة تحتوي على البورون
SG172040A1 (en) 2008-12-17 2011-07-28 Anacor Pharmaceuticals Inc Polymorphs of (s)-3-aminomethyl-7-(3-hydroxy-propoxy)-3h-benzo[c][1,2] oxaborol-1-ol
WO2011037731A1 (en) * 2009-09-25 2011-03-31 Anacor Pharmaceuticals, Inc. Boron containing small molecules
AU2011237681B2 (en) 2010-04-07 2015-01-22 Glaxosmithkline Llc Process for preparing benzoxaboroles
CN108610356B (zh) 2010-09-07 2021-02-26 阿纳科制药公司 苯并氧杂硼杂环戊二烯衍生物用于治疗细菌感染
US8530452B2 (en) 2011-12-22 2013-09-10 Micurx Pharmaceuticals, Inc. Tricyclic boron compounds for antimicrobial therapy
CN102739587B (zh) 2012-06-16 2014-05-21 天地融科技股份有限公司 音频数据传输方法
KR101636431B1 (ko) 2013-07-30 2016-07-05 동아에스티 주식회사 트리사이클릭 벤즈옥사보롤 화합물, 이의 제조방법 및 용도
JP6499175B2 (ja) * 2013-08-09 2019-04-10 グラクソスミスクライン、インテレクチュアル、プロパティー、(ナンバー2)、リミテッドGlaxosmithkline Intellectual Property (No.2) Limited 三環式ベンゾキサボロール化合物及びその使用

Also Published As

Publication number Publication date
US11214582B2 (en) 2022-01-04
CN107531730B (zh) 2020-08-07
CY1123687T1 (el) 2022-03-24
HUE051113T2 (hu) 2021-01-28
US10774096B2 (en) 2020-09-15
CA2976308A1 (en) 2016-08-18
DOP2017000188A (es) 2017-09-15
CL2017002059A1 (es) 2018-03-16
DOP2017000189A (es) 2018-02-15
MA41494B1 (fr) 2020-10-28
EA201791667A1 (ru) 2018-02-28
CA2976030C (en) 2023-09-26
CO2017008809A2 (es) 2017-11-10
EP3256480A1 (en) 2017-12-20
EP3256479A1 (en) 2017-12-20
CL2017002060A1 (es) 2018-03-16
BR112017017211B1 (pt) 2023-04-25
AU2016217508A1 (en) 2017-09-28
LT3256479T (lt) 2020-12-28
MA41495A (fr) 2017-12-19
TW201702250A (zh) 2017-01-16
CN107531730A (zh) 2018-01-02
MA41494A (fr) 2017-12-19
US20210053996A1 (en) 2021-02-25
JP2018506540A (ja) 2018-03-08
MX2017010414A (es) 2018-05-11
PH12017501427A1 (en) 2018-01-15
IL253865A0 (en) 2017-10-31
EA201791671A1 (ru) 2018-02-28
EA036516B1 (ru) 2020-11-18
CR20170372A (es) 2017-10-19
WO2016128948A1 (en) 2016-08-18
PE20171432A1 (es) 2017-09-26
CN107548398A (zh) 2018-01-05
WO2016128949A1 (en) 2016-08-18
PH12017501428A1 (en) 2018-01-15
BR112017017211A2 (pt) 2018-04-03
IL253864B (en) 2021-07-29
MX2017010413A (es) 2018-05-11
UA120527C2 (uk) 2019-12-26
EP3256479B1 (en) 2020-07-29
PT3256479T (pt) 2020-10-22
SI3256479T1 (sl) 2020-11-30
ES2821951T3 (es) 2021-04-28
PE20171348A1 (es) 2017-09-13
TW201643173A (zh) 2016-12-16
HRP20201597T1 (hr) 2020-12-25
KR20170117156A (ko) 2017-10-20
RS60885B1 (sr) 2020-11-30
AU2016217507A1 (en) 2017-09-28
JP6771472B2 (ja) 2020-10-21
MY194004A (en) 2022-11-07
BR112017017213A2 (pt) 2018-04-03
US20180037595A1 (en) 2018-02-08
ZA201705456B (en) 2019-10-30
DK3256479T3 (da) 2020-11-02
KR20170117158A (ko) 2017-10-20
TWI730953B (zh) 2021-06-21
PL3256479T3 (pl) 2021-06-14
IL253864A0 (en) 2017-09-28
SG11201706510YA (en) 2017-09-28
AU2016217507B2 (en) 2019-03-14
CA2976030A1 (en) 2016-08-18
CO2017008816A2 (es) 2017-11-10
US20180044353A1 (en) 2018-02-15
CR20170371A (es) 2018-01-22
AU2020256369A1 (en) 2020-11-12
JP2018506538A (ja) 2018-03-08
NZ734379A (en) 2023-06-30

Similar Documents

Publication Publication Date Title
ZA201804070B (en) Eif4-a-inhibiting compounds and methods related thereto
SG11201706029VA (en) Anti-senescence compounds and uses thereof
HK1246780A1 (zh) 氮雜-吡啶酮化合物及其用途
ZA201705456B (en) Benzoxaborole compounds and uses thereof
HK1257539A1 (zh) 新的化合物及其用途
GB201504763D0 (en) Compounds and uses
GB201616439D0 (en) Compounds and uses
HK1247122A1 (zh) 組合及其用途
GB201507753D0 (en) New compounds and uses
IL254241A0 (en) Etv2 and its uses
HK1250915A1 (zh) 組合物和其用途
IL253459A0 (en) Isoergoline compounds and their uses
GB201718875D0 (en) Autophagy-inhibiting compounds and uses thereof
GB201501593D0 (en) New compounds and processes
GB201614224D0 (en) Compounds and uses thereof
IL258458B (en) Peroxyhemiacetal profragrant and proflavor compounds
GB2543375B (en) Compounds and their uses
GB201614874D0 (en) New compounds and uses
GB201621467D0 (en) Modified bulgeomers
GB201616374D0 (en) Modified bulgeomers
GB201614858D0 (en) Modified Bulgeomers
GB201507752D0 (en) New compounds and uses
GB201514770D0 (en) Compounds and their use
GB201602572D0 (en) New compound and uses
GB201516922D0 (en) New processes and compounds