SG11201703500XA - Perfusion bioreactor platform - Google Patents

Perfusion bioreactor platform

Info

Publication number
SG11201703500XA
SG11201703500XA SG11201703500XA SG11201703500XA SG11201703500XA SG 11201703500X A SG11201703500X A SG 11201703500XA SG 11201703500X A SG11201703500X A SG 11201703500XA SG 11201703500X A SG11201703500X A SG 11201703500XA SG 11201703500X A SG11201703500X A SG 11201703500XA
Authority
SG
Singapore
Prior art keywords
perfusion bioreactor
bioreactor platform
platform
perfusion
bioreactor
Prior art date
Application number
SG11201703500XA
Inventor
Gregory Roger Martin
Allison Jean Tanner
Original Assignee
Corning Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Corning Inc filed Critical Corning Inc
Publication of SG11201703500XA publication Critical patent/SG11201703500XA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/12—Well or multiwell plates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • C12M1/14—Apparatus for enzymology or microbiology with means providing thin layers or with multi-level trays
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/16—Microfluidic devices; Capillary tubes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/14—Scaffolds; Matrices
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/10—Perfusion
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M3/00—Tissue, human, animal or plant cell, or virus culture apparatus
    • C12M3/04—Tissue, human, animal or plant cell, or virus culture apparatus with means providing thin layers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M3/00—Tissue, human, animal or plant cell, or virus culture apparatus

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Sustainable Development (AREA)
  • Clinical Laboratory Science (AREA)
  • Dispersion Chemistry (AREA)
  • Virology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
SG11201703500XA 2014-10-29 2015-10-29 Perfusion bioreactor platform SG11201703500XA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462072039P 2014-10-29 2014-10-29
PCT/US2015/058032 WO2016069885A1 (en) 2014-10-29 2015-10-29 Perfusion bioreactor platform

Publications (1)

Publication Number Publication Date
SG11201703500XA true SG11201703500XA (en) 2017-05-30

Family

ID=54477374

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201703500XA SG11201703500XA (en) 2014-10-29 2015-10-29 Perfusion bioreactor platform

Country Status (7)

Country Link
US (2) US11613722B2 (en)
EP (1) EP3212760A1 (en)
JP (1) JP6930914B2 (en)
KR (1) KR102470508B1 (en)
CN (2) CN107109339B (en)
SG (1) SG11201703500XA (en)
WO (1) WO2016069885A1 (en)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9790465B2 (en) 2013-04-30 2017-10-17 Corning Incorporated Spheroid cell culture well article and methods thereof
SG11201703500XA (en) 2014-10-29 2017-05-30 Corning Inc Perfusion bioreactor platform
EP3212759A1 (en) 2014-10-29 2017-09-06 Corning Incorporated Cell culture insert
CN109790503A (en) * 2016-09-22 2019-05-21 康宁股份有限公司 Gravity streaming cell culture apparatus, system and its application method
JP2018108038A (en) * 2016-12-28 2018-07-12 クアーズテック株式会社 Cell culture carrier
US20200040294A1 (en) * 2017-01-18 2020-02-06 Shinko Chemical Co., Ltd. Device for evaluation of chemical substance and method for evaluation of chemical substance
WO2019014610A1 (en) 2017-07-14 2019-01-17 Corning Incorporated Cell culture vessel for 3d culture and methods of culturing 3d cells
US11857970B2 (en) 2017-07-14 2024-01-02 Corning Incorporated Cell culture vessel
JP7245222B2 (en) * 2017-07-14 2023-03-23 コーニング インコーポレイテッド 3D cell culture vessel for manual or automatic medium exchange
JP7197557B2 (en) 2017-07-14 2022-12-27 コーニング インコーポレイテッド Cell culture vessel with porous support
PL3649229T3 (en) 2018-07-13 2021-12-06 Corning Incorporated Cell culture vessels with stabilizer devices
US11661574B2 (en) 2018-07-13 2023-05-30 Corning Incorporated Fluidic devices including microplates with interconnected wells
US11912968B2 (en) 2018-07-13 2024-02-27 Corning Incorporated Microcavity dishes with sidewall including liquid medium delivery surface
JP7179548B2 (en) * 2018-09-18 2022-11-29 テルモ株式会社 Bioreactor, cell culture system and cell culture method
CN109251859B (en) * 2018-10-11 2021-11-05 广州洁特生物过滤股份有限公司 Cell culture device and cell box thereof
JP7348586B2 (en) * 2019-01-18 2023-09-21 東洋製罐グループホールディングス株式会社 Culture container, culture method, and culture device
WO2020246572A1 (en) * 2019-06-07 2020-12-10 株式会社日本触媒 Method for recovering cells and/or aggregates thereof
AU2020358122B2 (en) * 2019-09-30 2023-06-29 OminiWell Pty Ltd Three-dimensional cell culture platform and uses thereof
WO2022093883A1 (en) * 2020-10-30 2022-05-05 Corning Incorporated Microcavity plate
CN116472337A (en) * 2020-11-20 2023-07-21 康宁股份有限公司 Perforated microcavity plate
KR20220092275A (en) * 2020-12-24 2022-07-01 주식회사 넥스트앤바이오 Cell culture plate stacked arrangement
TWI751902B (en) * 2021-01-29 2022-01-01 錢家琪 Cell culture platform and method for manufacture the same
CN113070108B (en) * 2021-03-01 2022-05-06 清华大学 Preparation method of patterned hydrogel particles and microfluidic device

Family Cites Families (238)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2947116A (en) 1954-02-26 1960-08-02 Wilton R Earle Method of producing tissue culture flasks
US3630849A (en) 1969-04-24 1971-12-28 David B Land Surface micro-organism contamination assays
US4382685A (en) 1979-07-17 1983-05-10 Techne (Cambridge) Limited Method and apparatus for stirring particles in suspension such as microcarriers for anchorage-dependent living cells in a liquid culture medium
DE8309876U1 (en) 1983-04-02 1983-12-22 Biotest-Serum-Institut Gmbh, 6000 Frankfurt TWO-PHASE BLOOD CULTURE BOTTLE
GB8321239D0 (en) 1983-08-05 1983-09-07 Orbec Ltd Innoculating means
US4670396A (en) 1985-05-02 1987-06-02 Bioassy Systems Corporation Vertical culture system with removable culture unit
US5171994A (en) 1986-08-13 1992-12-15 Northrop Corporation Infrared staring imaging array
US5047347A (en) 1987-08-17 1991-09-10 Cline Martin J Gas permeable culture flask and method for culturing mammalian cells
US4839292B1 (en) 1987-09-11 1994-09-13 Joseph G Cremonese Cell culture flask utilizing membrane barrier
US4927764A (en) 1987-11-17 1990-05-22 Costar Corporation Tissue culture flask
US4980293A (en) 1988-09-02 1990-12-25 Multi-Technology Inc. Dispensing reagents in a specimen well
US5240854A (en) * 1989-06-05 1993-08-31 Berry Eric S Continuous high-density cell culture system
JP2850982B2 (en) 1989-10-25 1999-01-27 ユニ・チャーム株式会社 Disposable wearing articles
GB9004911D0 (en) 1990-03-05 1990-05-02 Smith & Nephew Cell culture products
US5712137A (en) 1990-03-05 1998-01-27 Smith & Nephew Plc Laminate of a culture substrate on a carrier for producing an apertured wound dressing
DE4030699C1 (en) 1990-09-28 1991-10-10 Bruker Analytische Messtechnik Gmbh, 7512 Rheinstetten, De
US5272083A (en) 1990-10-10 1993-12-21 Costar Corporation Culture device and method of use having a detachable cell or tissue growth surface
US5151366A (en) 1991-05-24 1992-09-29 Invitro Scientific Products, Inc. Cell culture flask
DE4132379A1 (en) 1991-09-28 1993-04-08 Kernforschungsz Karlsruhe SUBSTRATE FOR CELL CULTURES AND CULTURE OF CELLS OR CELL AGGREGATES
US5272084A (en) 1991-12-18 1993-12-21 Corning Incorporated Cell culture vessels having interior ridges and method for cultivating cells in same
US5319436A (en) 1992-05-28 1994-06-07 Packard Instrument Company, Inc. Microplate farming wells with transparent bottom walls for assays using light measurements
IT1266389B1 (en) 1993-02-15 1996-12-30 Alberto Degrassi CONTAINER STRUCTURE, PARTICULARLY FOR CELL CULTURES
US5374557A (en) 1993-04-29 1994-12-20 Verma; Kuldeep Fermentation vessels and closures therefor
JP3152933B2 (en) 1993-05-17 2001-04-03 アマーシャム・インターナショナル・ピーエルシー Apparatus and method for measuring cell biochemical processes
JP2716646B2 (en) 1993-05-21 1998-02-18 住友ベークライト株式会社 Method for forming cell aggregates
CN2186755Y (en) 1994-03-25 1995-01-04 中国科学院成都生物研究所 Multipurpose culture plate
US5487872A (en) 1994-04-15 1996-01-30 Molecular Device Corporation Ultraviolet radiation transparent multi-assay plates
US5707869A (en) 1994-06-28 1998-01-13 Wolf; Martin L. Compartmentalized multiple well tissue culture plate
US5693537A (en) 1994-06-28 1997-12-02 Wilson; John R. Compartmentalized tissue culture flask
US5635344A (en) 1994-12-07 1997-06-03 Cedra Corp. Shipping medium for organ-derived cells
US5554536A (en) 1995-01-05 1996-09-10 Millipore Investment Holdings Limited Biological analysis device having improved contamination prevention
GB9509487D0 (en) 1995-05-10 1995-07-05 Ici Plc Micro relief element & preparation thereof
US5710043A (en) 1995-09-25 1998-01-20 Becton Dickinson And Company In vitro cell culture assembly
US5759494A (en) 1995-10-05 1998-06-02 Corning Incorporated Microplates which prevent optical cross-talk between wells
US5772905A (en) 1995-11-15 1998-06-30 Regents Of The University Of Minnesota Nanoimprint lithography
FR2741357B1 (en) 1995-11-22 1998-01-16 Corning Inc METHOD FOR MANUFACTURING A SUPPORT PLATE FOR A TWO-DIMENSIONAL NETWORK OF MICROWELLS, IN PARTICULAR FOR BIOLOGICAL TESTING OR CULTURE
JP3139350B2 (en) * 1995-12-05 2001-02-26 トヨタ自動車株式会社 Solenoid valve device
JPH09234811A (en) 1995-12-27 1997-09-09 Mitsubishi Gas Chem Co Inc Film-like or sheet-like deoxidizing multilayer body and its manufacture
JPH09173049A (en) 1995-12-27 1997-07-08 Sumitomo Bakelite Co Ltd Culturing vessel
US5858309A (en) 1996-03-22 1999-01-12 Corning Incorporated Microplates with UV permeable bottom wells
US5783440A (en) 1996-09-30 1998-07-21 Becton Dickinson And Company Culture vessel
JP2001502057A (en) 1996-10-10 2001-02-13 コーニング インコーポレイテッド Device for transferring droplets and method for transferring droplets using such device
CN1244140A (en) 1997-01-17 2000-02-09 康宁股份有限公司 Multi-well plate
JPH10210966A (en) 1997-01-29 1998-08-11 Sumitomo Bakelite Co Ltd Culture vessel
JPH10210866A (en) 1997-01-30 1998-08-11 Masayuki Minato Falling prevention instrument for flowerpot not to be laid fallen even by strong wind
US5972694A (en) 1997-02-11 1999-10-26 Mathus; Gregory Multi-well plate
US5859896A (en) 1997-03-05 1999-01-12 Rosen; Howard B. Telephone line automatic prefix dialer
DE19712484C2 (en) 1997-03-25 1999-07-08 Greiner Gmbh Microplate with transparent bottom and process for its production
CH692583A5 (en) 1998-03-03 2002-08-15 Weidmann H Ag Culture vessel.
DE19825812C1 (en) 1998-06-09 2000-01-13 Gsf Forschungszentrum Umwelt Cell culture vessel for the cultivation of non-adherent cells
GB9812783D0 (en) 1998-06-12 1998-08-12 Cenes Ltd High throuoghput screen
GB9912641D0 (en) 1999-05-28 1999-07-28 Ashby Scient Ltd Textured and porous silicone rubber
JP4315544B2 (en) 1999-10-04 2009-08-19 日油株式会社 Copolymer, production method thereof, medical material and ophthalmic material
US6521451B2 (en) 1999-12-09 2003-02-18 California Institute Of Technology Sealed culture chamber
DE10019862A1 (en) 2000-04-18 2001-11-08 Cell Lining Ges Fuer Zellkulti Method for automated medium exchange, useful in cell cultures, uses transparent, hollow perfusion cover for supply and removal of medium
DE60143703D1 (en) 2000-04-19 2011-02-03 Corning Inc MULTIPLE PLATE AND ITS MANUFACTURING PROCESS
DE10046175A1 (en) 2000-09-19 2002-03-28 Augustinus Bader Automatic culturing and treatment of cells, especially for diagnosis, employs cell culture plate with wells supplied with oxygen and nutrients
US6811752B2 (en) 2001-05-15 2004-11-02 Biocrystal, Ltd. Device having microchambers and microfluidics
ES2270212T3 (en) 2001-06-14 2007-04-01 Millipore Corporation MULTIPOYCLE CULTURE CELL APPLIANCE.
CA2351156A1 (en) 2001-07-04 2003-01-04 Peter W. Zandstra A bioprocess for the generation of pluripotent cell derived cells and tissues
EP1428871B1 (en) 2001-07-26 2008-08-27 Transparent Inc. Cultured cell construct containing spheroids of cultured animal cells and utilization thereof
US6767607B2 (en) 2001-08-09 2004-07-27 Corning Incorporated Multiwell plate having transparent well bottoms
FR2830107B1 (en) 2001-09-24 2004-09-24 Gemplus Card Int ELECTRONIC KEY FOR CONNECTION TO A PORT OF A TELECOMMUNICATION DEVICE AND METHOD FOR MANUFACTURING THE KEY
AU2002363076A1 (en) 2001-10-26 2003-05-06 Virtual Arrays, Inc. Assay systems with adjustable fluid communication
JP2003135056A (en) 2001-10-30 2003-05-13 Mitsuo Ochi Method for producing tissue equivalent for transplantation and instrument for producing the same
JP2003180335A (en) 2001-12-21 2003-07-02 Sumitomo Bakelite Co Ltd Storable culture vessel
CA2475804C (en) 2002-02-12 2015-04-14 Bhp Billiton Innovation Pty Ltd Airborne vector magnetic surveys
EP1490520A4 (en) 2002-03-12 2006-06-07 Surface Logix Inc Assay device that analyzes the absorption, metabolism, permeability and/or toxicity of a candidate compound
AU2003223416A1 (en) 2002-03-25 2003-10-13 Condros, Inc. Tissue analogs for in vitro testing and method of use therefor
US20030183958A1 (en) 2002-03-28 2003-10-02 Becton, Dickinson And Company Multi-well plate fabrication
DE60313263T2 (en) 2002-09-20 2007-12-27 Becton Dickinson And Co. roller bottle
JP3764959B2 (en) 2002-10-10 2006-04-12 独立行政法人理化学研究所 Cell culture container and cell culture method
DE60333715D1 (en) 2002-10-30 2010-09-23 Hitachi Ltd Process for the preparation of functional substrates having columnar microcolumns
US20040091397A1 (en) 2002-11-07 2004-05-13 Corning Incorporated Multiwell insert device that enables label free detection of cells and other objects
FI115060B (en) 2003-04-22 2005-02-28 Chip Man Technologies Oy Analysis and breeding equipment
WO2004097415A1 (en) 2003-04-25 2004-11-11 Jsr Corporation Biochip and biochip kit, and method of producing the same and method of using the same
US7425440B2 (en) 2003-06-10 2008-09-16 The Automation Partnership (Cambridge) Limited Culture flask
US20050032208A1 (en) 2003-06-18 2005-02-10 Oh Steve Kah Weng Materials and methods to produce stem cells
US8597597B2 (en) 2003-06-26 2013-12-03 Seng Enterprises Ltd. Picoliter well holding device and method of making the same
CA2558946C (en) 2003-07-08 2013-05-21 Axiogenesis Ag Novel method for the preparation of embryoid bodies (ebs) and uses thereof
US20050112030A1 (en) 2003-08-21 2005-05-26 Gaus Stephanie E. Meshwell plates
AU2004280623B2 (en) 2003-10-08 2010-12-02 Wilson Wolf Manufacturing, LLC Cell culture methods and devices utilizing gas permeable materials
US8658349B2 (en) 2006-07-13 2014-02-25 Seahorse Bioscience Cell analysis apparatus and method
US7186548B2 (en) * 2003-11-10 2007-03-06 Advanced Pharmaceutical Sciences, Inc. Cell culture tool and method
JP2007515958A (en) 2003-12-19 2007-06-21 ユニヴァーシティー オブ ウォータールー Cultured cells, cell culture methods and equipment
DK1720972T3 (en) 2004-03-05 2014-04-14 Dsm Ip Assets Bv METHOD OF CELL CULTIVATION USING CONTINUOUS PERFUSION AND ALTERNATIVE TANGENTIAL FLOW
JP2007537759A (en) 2004-05-19 2007-12-27 マサチューセッツ・インスティテュート・オブ・テクノロジー Perfusion 3D cell / tissue disease model
WO2006019836A1 (en) 2004-07-22 2006-02-23 Corning Incorporated Culture flask
US7767446B2 (en) 2004-09-16 2010-08-03 Becton, Dickinson And Company Perfusion bioreactors for culturing cells
WO2006043267A1 (en) * 2004-10-18 2006-04-27 Seng Enterprises Ltd. Current damper for the study of cells
JP3981929B2 (en) 2004-10-29 2007-09-26 財団法人北九州産業学術推進機構 Cell tissue microchip
JP4672376B2 (en) 2005-01-11 2011-04-20 株式会社クラレ Cell culture method with controlled extension direction
GB2427688A (en) 2005-06-28 2007-01-03 Inogen S A Microwell plate
US7829581B2 (en) 2005-07-15 2010-11-09 Laboratorios Del Dr. Esteve, S.A. Prodrugs of pyrazoline compounds, their preparation and use as medicaments
US7745209B2 (en) * 2005-07-26 2010-06-29 Corning Incorporated Multilayered cell culture apparatus
NZ566070A (en) 2005-08-01 2011-05-27 Invitrogen Corp Labels, containers, system and methods for providing reagents
EP1976972B1 (en) 2006-01-24 2014-03-12 Brown University Cell aggregation and encapsulation device and method
JP5397934B2 (en) 2006-02-21 2014-01-22 Ｓｃｉｖａｘ株式会社 Spheroids and method for producing the same
EP1988153B1 (en) 2006-02-24 2019-06-19 Corning Incorporated Cell culture container and method of producing the same
ITMI20061063A1 (en) 2006-05-31 2007-12-01 Mindseeds Lab S R L METRODO AND PE SYSTEM RLA SELECTION AND MODIFICATION OF SINGLE CELLS AND THEIR SMALL AGGREGATES
DE102006030068A1 (en) 2006-06-28 2008-01-03 M2P-Labs Gmbh Apparatus and method for the supply and removal of fluids in shaken microreactors arrays
US7745210B2 (en) 2006-06-30 2010-06-29 Corning Incorporated Fluid flow diverter for cell culture vessel
US9175254B2 (en) 2006-07-07 2015-11-03 University Of Miami Enhanced oxygen cell culture platforms
EP2044192B1 (en) 2006-07-07 2017-04-12 University of Miami Enhanced oxygen cell culture platforms
US8053230B2 (en) 2006-09-07 2011-11-08 Nalge Nunc International Corporation Culture dish with lid
US8486692B2 (en) 2006-11-14 2013-07-16 Acme Biosystems Llc Cell culture apparatus and associated methods
US20080118974A1 (en) 2006-11-20 2008-05-22 Gregory Roger Martin Large scale cell culture vessel
DE202006017853U1 (en) 2006-11-23 2007-01-18 Forschungszentrum Karlsruhe Gmbh Synthetic thermoplastic insert for a mocrotiter plate for the cultivation of different cells, comprises carrier structure, conically tapered recesses arranged in the carrier structure, and perforation and foil joint between the recesses
CN101611133A (en) 2006-12-07 2009-12-23 威尔森沃尔夫制造公司 The method of high-performance device and culturing cell
US7897379B2 (en) * 2007-02-26 2011-03-01 Corning Incorporated Device and method for reducing bubble formation in cell culture
US20110086375A1 (en) 2007-03-02 2011-04-14 Mark Ungrin Devices and methods for production of cell aggregates
WO2008118500A1 (en) 2007-03-27 2008-10-02 Wafergen, Inc. Nutrient perfusion plate with heater & gas exchange for high content screening
KR100836827B1 (en) 2007-04-09 2008-06-10 전남대학교산학협력단 Cell culture dish for the embryoid body formation from embryonic stem cells
WO2008140295A1 (en) 2007-05-16 2008-11-20 Erasmus University Medical Center Rotterdam Cell culture substrate, culture flasks and methods for cell cultivation employing said substrate
DE102007027273A1 (en) 2007-05-24 2008-11-27 Heipha Gmbh Container for receiving nutrient media
FR2916451A1 (en) 2007-05-25 2008-11-28 Mhs Ind Soc Par Actions Simpli SYSTEM FOR CULTIVATION OF BIOLOGICAL CELLS
US9309491B2 (en) 2007-05-29 2016-04-12 Corning Incorporated Cell culture apparatus for co-culture of cells
KR20160005142A (en) 2007-06-29 2016-01-13 셀룰러 다이내믹스 인터내셔널, 인코포레이티드 Automated method and apparatus for embryonic stem cell culture
JP5233187B2 (en) 2007-07-11 2013-07-10 パナソニック株式会社 Cell electrophysiological sensor
JP2009050194A (en) 2007-08-27 2009-03-12 Sumitomo Bakelite Co Ltd Vessel for cell aggregate-forming culture
JP3139350U (en) * 2007-11-27 2008-02-14 株式会社クラレ Cell culture vessel
CN101978041B (en) * 2008-01-25 2014-07-30 康宁股份有限公司 Limited access multi-layer cell culture system
DE602008002545D1 (en) 2008-02-01 2010-10-28 Eppendorf Ag Culture plate with flap for side ventilation
US20100112014A1 (en) 2008-04-11 2010-05-06 Gilbert Ryan J Novel hydrogel compositions and methods of using
CN102046773A (en) 2008-05-30 2011-05-04 康宁股份有限公司 Cell culture apparatus having different micro-well topography
WO2009148507A1 (en) 2008-05-30 2009-12-10 Corning Incorporated Cell culture apparatus having variable topography
US8178345B2 (en) 2008-05-30 2012-05-15 Corning Incorporated Multilayer cell culture vessels
US8216828B2 (en) * 2008-05-30 2012-07-10 Corning Incorporated Assembly of cell culture vessels
EP2297295A4 (en) * 2008-07-08 2013-11-27 Wolf Wilson Mfg Corp Improved gas permeable cell culture device and method of use
WO2010008566A2 (en) * 2008-07-16 2010-01-21 Millipore Corporation A single or multitier cell culture system
EP2342317B1 (en) 2008-09-22 2012-12-19 University Of Zurich Prorektorat Forschung Hanging drop plate
JP5578779B2 (en) 2008-10-08 2014-08-27 国立大学法人東北大学 Spheroid culture method and spheroid culture vessel
WO2010042072A1 (en) 2008-10-08 2010-04-15 Agency For Science, Technology And Research Apparatus for culturing anchorage dependent cells
JP5288171B2 (en) 2008-10-31 2013-09-11 旭硝子株式会社 Cultivation container
US20110229961A1 (en) 2008-11-05 2011-09-22 Nanopoint, Inc. Active microfluidic system for in vitro culture
US8956867B2 (en) 2008-11-07 2015-02-17 Wisconsin Alumni Research Foundation Method for culturing stem cells
ES2343721B1 (en) 2008-12-19 2011-06-06 Histocell, S.L. CELL TRANSPORTATION SYSTEM.
JP2010158214A (en) 2009-01-09 2010-07-22 Olympus Corp Culture vessel
DE102009005526A1 (en) * 2009-01-20 2010-07-22 Universität Duisburg-Essen Bioreactor for biomass production by living species, comprises flat beds, which are provided for medium containing living species and have transparent and/or gas-permeable bottom, lighting device between each of the beds, and light guide
US20120064627A1 (en) 2009-01-26 2012-03-15 The Regents Of The University Of California Apparatus and method for culturing stem cells
US8163537B2 (en) 2009-01-27 2012-04-24 Corning Incorporated Nested permeable support device and method for using the nested permeable support device
DE102009013673A1 (en) 2009-03-09 2010-09-16 Eppendorf Ag Cell culture dish
WO2010107497A2 (en) 2009-03-18 2010-09-23 The Regents Of The University Of California Honeycomb shrink wells for stem cell culture
CN102449135B (en) 2009-03-26 2014-07-09 新加坡科技研究局 Apparatus for cell or tissue culture
JP2012527217A (en) 2009-04-24 2012-11-08 ジ・オハイオ・ステート・ユニバーシティ Bidirectional microenvironment system
US9169460B2 (en) 2009-05-19 2015-10-27 Lifeglobal Group Llc Flooding dish and method for changing media in the dish in the preparation of mammalian specimen culture and for cryo-preservation, freezing, vitrification and the thawing and warming of such specimens
US8778669B2 (en) 2009-07-22 2014-07-15 Corning Incorporated Multilayer tissue culture vessel
US8143053B2 (en) 2009-10-26 2012-03-27 Biomerieux, Inc. Lockable cell growth chamber with antilocking feature
US20120219572A1 (en) 2009-11-12 2012-08-30 Prockop Darwin J Spheroidal Aggregates of Mesenchymal Stem Cells
US20130122580A1 (en) 2010-01-08 2013-05-16 Sumitomo Bakelite Co., Ltd. Culture vessel for forming aggregated cell mass
US9493733B2 (en) 2010-01-18 2016-11-15 Becton, Dickinson And Company Container assembly
WO2011094572A2 (en) 2010-01-28 2011-08-04 Shuichi Takayama Hanging drop devices, systems and/or methods
CN201626959U (en) 2010-02-01 2010-11-10 中国农业科学院北京畜牧兽医研究所 Micro perfusion device for cell culture
JP2011172533A (en) 2010-02-25 2011-09-08 Fusao Komada Method for three-dimensional high-density cell culture using microspace structure
WO2011139233A1 (en) 2010-05-04 2011-11-10 Agency For Science, Technology And Research A microsieve for cells and particles filtration
JP5703302B2 (en) * 2010-09-08 2015-04-15 株式会社島津製作所 Cell culture container and cell culture method using the container
WO2012036011A1 (en) 2010-09-14 2012-03-22 旭硝子株式会社 Culture substrate
US9260684B1 (en) 2010-11-11 2016-02-16 Stemcell Technologies Inc. Cell culture device
WO2012103109A2 (en) 2011-01-24 2012-08-02 California Stem Cell, Inc. Neural cell purification for transplantation
TWI438273B (en) 2011-03-08 2014-05-21 Univ Chang Gung High-throughput perfusative microfluidic cell culture wafers for miniaturized three-dimensional cell culture
GB201105226D0 (en) 2011-03-29 2011-05-11 Univ Leiden Methods
CN104673670A (en) 2011-03-30 2015-06-03 独立行政法人国立长寿医疗研究中心 Membrane-separation-type Culture Device, Membrane-separation-type Culture Kit, Stem Cell Separation Method Using Same, And Separation Membrane
JP2012249547A (en) 2011-05-31 2012-12-20 Oji Holdings Corp Cell culture substrate and method for manufacturing the same
US20140193900A1 (en) 2011-06-09 2014-07-10 Ivar Meyvantsson Device for washing suspended cells or particles
JP5853512B2 (en) 2011-09-08 2016-02-09 大日本印刷株式会社 Cell culture container and manufacturing method thereof
KR20170061723A (en) 2011-09-20 2017-06-05 주식회사 쿠라레 Adherent cell culture method
US9200246B2 (en) 2011-12-01 2015-12-01 Acea Biosciences, Inc. Co-culture device assembly
US9862918B2 (en) 2012-01-19 2018-01-09 Yamaha Hatsudoki Kabushiki Kaisha Well plate and suction device provided with well plate
US20150004686A1 (en) 2012-02-02 2015-01-01 Corning Incorporated Automatic continuous perfusion cell culture microplate consumables
CN202450098U (en) 2012-03-09 2012-09-26 山东省农业科学院畜牧兽医研究所 Culture bottle for primary explant culture cells
EP2653531A1 (en) 2012-04-18 2013-10-23 Oxyphen AG Culture assembly
US20140004086A1 (en) 2012-06-29 2014-01-02 Tissue Genesis Inc. Formation of cell aggregates
JP6111673B2 (en) 2012-07-25 2017-04-12 住友電気工業株式会社 Silicon carbide semiconductor device
USD685497S1 (en) 2012-08-31 2013-07-02 Corning Incorporated Cell culture flask
US9573128B1 (en) 2012-09-06 2017-02-21 SciKon Innovation, Inc. Fluidics device allowing fluid flow between a plurality of wells
EP2896684A4 (en) 2012-09-14 2015-12-23 Sumitomo Bakelite Co Microwell plate
CN202849407U (en) 2012-09-26 2013-04-03 无锡耐思生物科技有限公司 Cell culture flask structure
US9701938B2 (en) 2012-10-12 2017-07-11 Lena Biosciences, Inc. Intra-culture perfusion methods and applications thereof
KR20140048733A (en) 2012-10-16 2014-04-24 삼성전자주식회사 Multiwell plate and method for analyzing target material using the same
US9176115B2 (en) 2012-10-26 2015-11-03 The University Of Akron Engineering individually addressable cellular spheroids using aqueous two-phase systems
GB2507744A (en) 2012-11-07 2014-05-14 Universitaetsklinikum Freiburg Matrix for generating and cultivating uniform cell aggregations
US9494577B2 (en) 2012-11-13 2016-11-15 Seahorse Biosciences Apparatus and methods for three-dimensional tissue measurements based on controlled media flow
JP2014132869A (en) 2013-01-11 2014-07-24 Sumitomo Bakelite Co Ltd Cell culture vessel
US10072241B2 (en) 2013-03-13 2018-09-11 Innovative Surface Technologies, Inc. Conical devices for three-dimensional aggregate(s) of eukaryotic cells
KR20140113139A (en) 2013-03-15 2014-09-24 고려대학교 산학협력단 Cell spheroid culture plate
EP2781591B1 (en) 2013-03-19 2017-05-03 Unisense Fertilitech A/S A tray, a system and a method for monitoring and culturing of a cell culture
WO2014156455A1 (en) 2013-03-28 2014-10-02 富士フイルム株式会社 Cell culturing tool
USD748812S1 (en) 2013-04-12 2016-02-02 Corning Incorporated Arched cell culture flask
KR102234887B1 (en) 2013-04-19 2021-04-01 주식회사 에이엔케이 Substrate For Cell Culture
US9790465B2 (en) 2013-04-30 2017-10-17 Corning Incorporated Spheroid cell culture well article and methods thereof
WO2014197550A1 (en) 2013-06-05 2014-12-11 David Kranbuehl Multi point method and apparatus for monitoring the aging and changes in corresponding tensile performance properties of a polymer
BR112015030041B1 (en) 2013-06-07 2021-01-12 Kuraray Co., Ltd. culture chamber and culture method
JP6307802B2 (en) 2013-07-05 2018-04-11 株式会社Ihi Culture vessel
JP2015029431A (en) 2013-07-31 2015-02-16 大日本印刷株式会社 Cell culture vessel
CN203513696U (en) 2013-08-27 2014-04-02 浙江硕华医用塑料有限公司 Cell culture flask
DE102013109450B4 (en) 2013-08-30 2015-04-02 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. exposure apparatus
DK3041926T3 (en) 2013-09-05 2020-06-08 Univ Bern DEVICE FOR IN-VITRO MODELING OF IN-VIVO TISSUE OF BODIES
JP2015050964A (en) 2013-09-06 2015-03-19 住友ベークライト株式会社 Multistage culture flask and production method of cell culture flask
JP6185816B2 (en) 2013-10-11 2017-08-23 Ａｇｃテクノグラス株式会社 Cell culture vessel
AU2014344726B2 (en) 2013-10-30 2019-01-17 Milica Radisic Devices and methods for three-dimensional tissue culturing
WO2015087369A1 (en) 2013-12-12 2015-06-18 ヤマハ発動機株式会社 Well plate and subject selection device provided with well plate
US20150247112A1 (en) 2014-03-03 2015-09-03 Kiyatec Inc. 3D Tissue Culture Devices and Systems
EP3114206B1 (en) 2014-03-04 2020-07-29 Pluristem Ltd. Systems and methods for growing and harvesting cells
DE102014214077A1 (en) 2014-07-18 2016-01-21 Hamilton Bonaduz Ag Laboratory containers, in particular cell culture containers, with a gas compensation line extending into the container volume
EP2985343A1 (en) 2014-08-11 2016-02-17 Karlsruher Institut für Technologie In vitro-co-culturesystem
WO2016064757A1 (en) 2014-10-19 2016-04-28 Nortis, Inc. Modular microfluidic system for perfused cell culture
US20170342363A1 (en) 2014-10-29 2017-11-30 Corning Incorporated Devices and methods for generation and culture of 3d cell aggregates
EP3212762A1 (en) 2014-10-29 2017-09-06 Corning Incorporated Spheroid trap insert
SG11201703500XA (en) 2014-10-29 2017-05-30 Corning Inc Perfusion bioreactor platform
EP3212759A1 (en) 2014-10-29 2017-09-06 Corning Incorporated Cell culture insert
CN113265332A (en) 2014-10-29 2021-08-17 康宁股份有限公司 Method and apparatus for generating and culturing 3D cell aggregates
WO2016069930A1 (en) 2014-10-29 2016-05-06 Corning Incorporated Microwell design and fabrication for generation of cell culture aggregates
DE102014017728A1 (en) 2014-12-01 2016-06-02 Merck Patent Gmbh Culture dish for micro-organisms
JP2016136921A (en) 2015-01-29 2016-08-04 大日本印刷株式会社 Cell culture container
JP2016136920A (en) 2015-01-29 2016-08-04 大日本印刷株式会社 Cell culture container
CN204752742U (en) 2015-03-12 2015-11-11 广州医科大学 Cell culture's cell culture ware can be used to to grow slowly
CN204702760U (en) 2015-04-15 2015-10-14 上海诺狄生物科技有限公司 A kind of culture dish
CN204714819U (en) 2015-04-21 2015-10-21 北京青藤谷禧干细胞科技研究院有限公司 A kind of Tissue Culture Flask of belt supporting frame
CN204608026U (en) 2015-04-22 2015-09-02 广州洁特生物过滤股份有限公司 A kind of cell with super hydrophilic growth surface embeds ware
CN204803327U (en) 2015-06-30 2015-11-25 广州洁特生物过滤股份有限公司 Ventilative cell culture dish
WO2017025584A1 (en) 2015-08-12 2017-02-16 Cytovac A/S A cell cultivation method, a cell cultivation vessel, and uses thereof
US20170067019A1 (en) 2015-09-07 2017-03-09 Bioreactor Sciences Llc Method of Continuous Mass Production of Progenitor Stem-like Cells Using a Bioreactor System
CN205990396U (en) 2015-09-09 2017-03-01 广州市迪景微生物科技有限公司 A kind of lid culture dish difficult for drop-off
JP6767375B2 (en) 2015-09-17 2020-10-14 Ａｇｃテクノグラス株式会社 Cell culture vessel
ES2615512B1 (en) 2015-11-06 2018-03-15 Universidad De Zaragoza DEVICE AND MICROFLUIDIC SYSTEM FOR THE STUDY OF CELL CULTURES
CN205170866U (en) 2015-12-08 2016-04-20 湖南人文科技学院 No clear tape embryo culture ware
NL2016281B1 (en) 2016-02-18 2017-08-24 Perkinelmer Health Sciences B V Means and methods for spheroid cell culturing and analysis.
US10774296B2 (en) 2016-04-05 2020-09-15 Corning Incorporated Lidded cell culture devices with improved handling performance and methods for using same
CN205669029U (en) 2016-05-09 2016-11-02 浙江硕华生命科学研究股份有限公司 A kind of cell culture ware
CN205839030U (en) 2016-07-27 2016-12-28 浙江译美生物科技有限公司 Tissue Culture Dish
EP3296018A1 (en) 2016-09-19 2018-03-21 Ecole Polytechnique Fédérale de Lausanne (EPFL) Organoid arrays
JP2018108032A (en) 2016-12-28 2018-07-12 Ａｇｃテクノグラス株式会社 Culture vessel
CN110709360A (en) 2017-04-27 2020-01-17 康宁公司 Method and apparatus for forming curved glass by differential heating of glass sheets
JP7197557B2 (en) 2017-07-14 2022-12-27 コーニング インコーポレイテッド Cell culture vessel with porous support
JP7245222B2 (en) 2017-07-14 2023-03-23 コーニング インコーポレイテッド 3D cell culture vessel for manual or automatic medium exchange
US20200181552A1 (en) 2017-07-14 2020-06-11 Corning Incorporated Handling features for microcavity cell culture vessel
EP3652294A1 (en) 2017-07-14 2020-05-20 Corning Incorporated Cell culture vessel
WO2019178039A1 (en) 2018-03-13 2019-09-19 Corning Incorporated High density 3d hepatocyte spheroid platform for drug adme studies

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