SG11201702558VA - Treatment of cancer with immune stimulators - Google Patents

Treatment of cancer with immune stimulators

Info

Publication number
SG11201702558VA
SG11201702558VA SG11201702558VA SG11201702558VA SG11201702558VA SG 11201702558V A SG11201702558V A SG 11201702558VA SG 11201702558V A SG11201702558V A SG 11201702558VA SG 11201702558V A SG11201702558V A SG 11201702558VA SG 11201702558V A SG11201702558V A SG 11201702558VA
Authority
SG
Singapore
Prior art keywords
cancer
treatment
immune stimulators
stimulators
immune
Prior art date
Application number
SG11201702558VA
Other languages
English (en)
Inventor
Robert S King
Cynthia Tuthill
Friedhelm Blobel
Original Assignee
Sciclone Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sciclone Pharmaceuticals Inc filed Critical Sciclone Pharmaceuticals Inc
Publication of SG11201702558VA publication Critical patent/SG11201702558VA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/2292Thymosin; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10Peptides having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/655Azo (—N=N—), diazo (=N2), azoxy (>N—O—N< or N(=O)—N<), azido (—N3) or diazoamino (—N=N—N<) compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/193Colony stimulating factors [CSF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/20Interleukins [IL]
    • A61K38/2013IL-2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/20Interleukins [IL]
    • A61K38/2046IL-7
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/21Interferons [IFN]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/21Interferons [IFN]
    • A61K38/212IFN-alpha
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2818Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
SG11201702558VA 2014-10-21 2015-10-21 Treatment of cancer with immune stimulators SG11201702558VA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462066862P 2014-10-21 2014-10-21
US201562215433P 2015-09-08 2015-09-08
PCT/US2015/056609 WO2016064969A1 (en) 2014-10-21 2015-10-21 Treatment of cancer with immune stimulators

Publications (1)

Publication Number Publication Date
SG11201702558VA true SG11201702558VA (en) 2017-05-30

Family

ID=55748164

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201702558VA SG11201702558VA (en) 2014-10-21 2015-10-21 Treatment of cancer with immune stimulators

Country Status (16)

Country Link
US (4) US9724395B2 (ja)
EP (2) EP3209321B1 (ja)
JP (2) JP6821560B2 (ja)
KR (1) KR102589557B1 (ja)
CN (2) CN107148279B (ja)
AU (1) AU2015335979B2 (ja)
BR (1) BR112017007817A2 (ja)
CA (1) CA2962451C (ja)
ES (1) ES2882080T3 (ja)
IL (1) IL251761B (ja)
MX (1) MX2017005134A (ja)
RU (2) RU2740288C2 (ja)
SG (1) SG11201702558VA (ja)
TW (2) TWI683667B (ja)
WO (1) WO2016064969A1 (ja)
ZA (1) ZA201702111B (ja)

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KR102589557B1 (ko) 2014-10-21 2023-10-16 시클론 파마수티컬 인터내셔널 리미티드 면역 자극인자를 이용한 암의 치료
SG11201803080YA (en) * 2015-10-21 2018-05-30 Teclison Ltd Compositions and methods for immune-mediated cancer therapy
WO2018138682A1 (en) * 2017-01-26 2018-08-02 Immune Therapeutics Methods and compositions useful for treating cancer
CN109793891A (zh) * 2017-11-17 2019-05-24 韩震 多肽化合物在制备提高治疗性抗体疗效的佐剂中的应用与组合物及其制备方法
EP3747433A4 (en) * 2018-02-02 2021-12-22 Cafa Therapeutics Limited CELLULAR IMMUNOTHERAPY ASSOCIATION
WO2020130300A1 (ko) 2018-12-21 2020-06-25 한미약품 주식회사 신규 면역 억제 인터루킨 2
IL295826A (en) 2020-03-31 2022-10-01 Hanmi Pharm Ind Co Ltd Novel il-2 analogs that stimulate the immune system
CN112023027B (zh) * 2020-07-21 2023-03-14 广东海洋大学 胸腺素或其衍生物的应用和治疗快感缺乏型抑郁症的药物
CN111821424B (zh) * 2020-07-21 2023-03-31 广东海洋大学深圳研究院 胸腺素及其衍生物的应用和治疗抑郁症的药物
US20240009317A1 (en) 2021-03-31 2024-01-11 Hanmi Pharm. Co., Ltd. Novel conjugate of immune-stimulating il-2 analog and preparation method thereof
WO2023069727A1 (en) * 2021-10-21 2023-04-27 Edison Oncology Compositions and methods for treatment of hyperproliferative, inflammatory, and immunological diseases, and infections

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HUT35524A (en) 1983-08-02 1985-07-29 Hoechst Ag Process for preparing pharmaceutical compositions containing regulatory /regulative/ peptides providing for the retarded release of the active substance
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KR102589557B1 (ko) 2014-10-21 2023-10-16 시클론 파마수티컬 인터내셔널 리미티드 면역 자극인자를 이용한 암의 치료

Also Published As

Publication number Publication date
CA2962451A1 (en) 2016-04-28
TW202034946A (zh) 2020-10-01
ZA201702111B (en) 2019-06-26
US11571465B2 (en) 2023-02-07
US9724395B2 (en) 2017-08-08
WO2016064969A1 (en) 2016-04-28
RU2017117194A3 (ja) 2019-04-09
EP3209321A1 (en) 2017-08-30
EP3943101A1 (en) 2022-01-26
EP3209321A4 (en) 2018-10-31
JP2021088557A (ja) 2021-06-10
TW201615209A (zh) 2016-05-01
AU2015335979B2 (en) 2021-05-20
JP7175334B2 (ja) 2022-11-18
MX2017005134A (es) 2018-02-12
TWI749433B (zh) 2021-12-11
KR20170070091A (ko) 2017-06-21
RU2017117194A (ru) 2018-11-22
JP6821560B2 (ja) 2021-01-27
RU2020142556A (ru) 2021-02-12
US20230285513A1 (en) 2023-09-14
IL251761B (en) 2020-09-30
US20160106812A1 (en) 2016-04-21
US20180161399A1 (en) 2018-06-14
KR102589557B1 (ko) 2023-10-16
US20200289618A1 (en) 2020-09-17
BR112017007817A2 (pt) 2017-12-19
CA2962451C (en) 2023-01-17
IL251761A0 (en) 2017-06-29
JP2018501192A (ja) 2018-01-18
CN113855806A (zh) 2021-12-31
ES2882080T3 (es) 2021-12-01
CN107148279B (zh) 2021-09-03
CN107148279A (zh) 2017-09-08
EP3209321B1 (en) 2021-06-23
RU2740288C2 (ru) 2021-01-12
TWI683667B (zh) 2020-02-01
AU2015335979A1 (en) 2017-04-20

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