SG11201702558VA - Treatment of cancer with immune stimulators - Google Patents
Treatment of cancer with immune stimulatorsInfo
- Publication number
- SG11201702558VA SG11201702558VA SG11201702558VA SG11201702558VA SG11201702558VA SG 11201702558V A SG11201702558V A SG 11201702558VA SG 11201702558V A SG11201702558V A SG 11201702558VA SG 11201702558V A SG11201702558V A SG 11201702558VA SG 11201702558V A SG11201702558V A SG 11201702558VA
- Authority
- SG
- Singapore
- Prior art keywords
- cancer
- treatment
- immune stimulators
- stimulators
- immune
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/2292—Thymosin; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/10—Peptides having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/655—Azo (—N=N—), diazo (=N2), azoxy (>N—O—N< or N(=O)—N<), azido (—N3) or diazoamino (—N=N—N<) compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/193—Colony stimulating factors [CSF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A61K38/2013—IL-2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A61K38/2046—IL-7
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
- A61K38/212—IFN-alpha
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2818—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201462066862P | 2014-10-21 | 2014-10-21 | |
US201562215433P | 2015-09-08 | 2015-09-08 | |
PCT/US2015/056609 WO2016064969A1 (en) | 2014-10-21 | 2015-10-21 | Treatment of cancer with immune stimulators |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201702558VA true SG11201702558VA (en) | 2017-05-30 |
Family
ID=55748164
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201702558VA SG11201702558VA (en) | 2014-10-21 | 2015-10-21 | Treatment of cancer with immune stimulators |
Country Status (16)
Country | Link |
---|---|
US (4) | US9724395B2 (ja) |
EP (2) | EP3209321B1 (ja) |
JP (2) | JP6821560B2 (ja) |
KR (1) | KR102589557B1 (ja) |
CN (2) | CN107148279B (ja) |
AU (1) | AU2015335979B2 (ja) |
BR (1) | BR112017007817A2 (ja) |
CA (1) | CA2962451C (ja) |
ES (1) | ES2882080T3 (ja) |
IL (1) | IL251761B (ja) |
MX (1) | MX2017005134A (ja) |
RU (2) | RU2740288C2 (ja) |
SG (1) | SG11201702558VA (ja) |
TW (2) | TWI683667B (ja) |
WO (1) | WO2016064969A1 (ja) |
ZA (1) | ZA201702111B (ja) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR102589557B1 (ko) | 2014-10-21 | 2023-10-16 | 시클론 파마수티컬 인터내셔널 리미티드 | 면역 자극인자를 이용한 암의 치료 |
SG11201803080YA (en) * | 2015-10-21 | 2018-05-30 | Teclison Ltd | Compositions and methods for immune-mediated cancer therapy |
WO2018138682A1 (en) * | 2017-01-26 | 2018-08-02 | Immune Therapeutics | Methods and compositions useful for treating cancer |
CN109793891A (zh) * | 2017-11-17 | 2019-05-24 | 韩震 | 多肽化合物在制备提高治疗性抗体疗效的佐剂中的应用与组合物及其制备方法 |
EP3747433A4 (en) * | 2018-02-02 | 2021-12-22 | Cafa Therapeutics Limited | CELLULAR IMMUNOTHERAPY ASSOCIATION |
WO2020130300A1 (ko) | 2018-12-21 | 2020-06-25 | 한미약품 주식회사 | 신규 면역 억제 인터루킨 2 |
IL295826A (en) | 2020-03-31 | 2022-10-01 | Hanmi Pharm Ind Co Ltd | Novel il-2 analogs that stimulate the immune system |
CN112023027B (zh) * | 2020-07-21 | 2023-03-14 | 广东海洋大学 | 胸腺素或其衍生物的应用和治疗快感缺乏型抑郁症的药物 |
CN111821424B (zh) * | 2020-07-21 | 2023-03-31 | 广东海洋大学深圳研究院 | 胸腺素及其衍生物的应用和治疗抑郁症的药物 |
US20240009317A1 (en) | 2021-03-31 | 2024-01-11 | Hanmi Pharm. Co., Ltd. | Novel conjugate of immune-stimulating il-2 analog and preparation method thereof |
WO2023069727A1 (en) * | 2021-10-21 | 2023-04-27 | Edison Oncology | Compositions and methods for treatment of hyperproliferative, inflammatory, and immunological diseases, and infections |
Family Cites Families (27)
Publication number | Priority date | Publication date | Assignee | Title |
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US3773919A (en) | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
DE2604845A1 (de) | 1976-02-07 | 1977-08-18 | Knoll Ag | Neue piperazinderivate |
IE52535B1 (en) | 1981-02-16 | 1987-12-09 | Ici Plc | Continuous release pharmaceutical compositions |
HUT35524A (en) | 1983-08-02 | 1985-07-29 | Hoechst Ag | Process for preparing pharmaceutical compositions containing regulatory /regulative/ peptides providing for the retarded release of the active substance |
US7235576B1 (en) | 2001-01-12 | 2007-06-26 | Bayer Pharmaceuticals Corporation | Omega-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors |
AR036993A1 (es) | 2001-04-02 | 2004-10-20 | Wyeth Corp | Uso de agentes que modulan la interaccion entre pd-1 y sus ligandos en la submodulacion de respuestas inmunologicas |
UA80957C2 (en) * | 2001-11-01 | 2007-11-26 | Sciclone Pharmaceuticals Inc | Method of administering a thymosin alpha 1 peptide |
CN101072582B (zh) * | 2004-12-06 | 2012-06-27 | 赛生制药有限公司 | 作为癌症疫苗佐剂的α胸腺肽 |
EP2161336B2 (en) * | 2005-05-09 | 2017-03-29 | ONO Pharmaceutical Co., Ltd. | Human monoclonal antibodies to programmed death 1(PD-1) and methods for treating cancer using anti-PD-1 antibodies alone or in combination with other immunotherapeutics |
CA2626859A1 (en) | 2005-11-08 | 2007-05-18 | Medarex, Inc. | Tnf-alpha blocker treatment for enterocolitis associated with immunostimulatory therapeutic antibody therapy |
CA2657821A1 (en) | 2006-07-21 | 2008-01-24 | Gilead Sciences, Inc. | Aza-peptide protease inhibitors |
US20080300166A1 (en) * | 2007-06-01 | 2008-12-04 | Sciclone Pharmaceuticals, Inc. | Treatment of Melanoma with Alpha Thymosin Peptides |
AR067412A1 (es) | 2007-07-06 | 2009-10-07 | Gilead Sciences Inc | Moduladores de propiedades farmaceuticas de productos terapeuticos |
US20090021740A1 (en) * | 2007-07-17 | 2009-01-22 | Chung Yuan Christian University | Optical sensor and method for measuring blood gas |
WO2009075813A1 (en) * | 2007-12-12 | 2009-06-18 | Sciclone Pharmaceuticals, Inc. | Treatment of melanoma with alpha thymosin peptides in combination with antibodies against cytotoxic t lymphocyte-associated antigen 4 (ctla4) |
EP2240194A4 (en) * | 2007-12-13 | 2011-12-21 | Sciclone Pharmaceuticals Inc | TREATMENT OF MELANOMA WITH ALPHA THYMOSIN PEPTIDES IN COMBINATION WITH A KINASE INHIBITOR |
CA2708168A1 (en) * | 2007-12-14 | 2009-06-25 | Sciclone Pharmaceuticals, Inc. | Treatment of melanoma with alpha thymosin peptides in combination with an antineoplastic heat shock apoptosis activator (hsaa) |
JP5945096B2 (ja) | 2008-07-04 | 2016-07-05 | 小野薬品工業株式会社 | 抗ヒトpd−1抗体の癌に対する治療効果を最適化するための判定マーカーの使用 |
AU2009290543B2 (en) | 2008-09-12 | 2015-09-03 | Oxford University Innovation Limited | PD-1 specific antibodies and uses thereof |
WO2010036959A2 (en) | 2008-09-26 | 2010-04-01 | Dana-Farber Cancer Institute | Human anti-pd-1, pd-l1, and pd-l2 antibodies and uses therefor |
US8741295B2 (en) | 2009-02-09 | 2014-06-03 | Universite De La Mediterranee | PD-1 antibodies and PD-L1 antibodies and uses thereof |
CN101591397A (zh) * | 2009-07-01 | 2009-12-02 | 石继红 | 长效胸腺素α1的重组表达及其用途 |
US20140213506A1 (en) * | 2011-02-09 | 2014-07-31 | Cynthia W. TUTHILL | Thymosin alpha peptide for preventing, reducing the severity of, and treating infection |
KR101970025B1 (ko) | 2011-04-20 | 2019-04-17 | 메디뮨 엘엘씨 | B7-h1 및 pd-1과 결합하는 항체 및 다른 분자들 |
JP5790345B2 (ja) * | 2011-09-07 | 2015-10-07 | 株式会社リコー | 画像処理装置、画像処理方法、プログラムおよび画像処理システム |
PT3381942T (pt) * | 2012-08-30 | 2021-05-24 | Amgen Inc | Método para o tratamento do melanoma que utiliza um vírus herpes simplex e um inibidor de checkpoint imunitário |
KR102589557B1 (ko) | 2014-10-21 | 2023-10-16 | 시클론 파마수티컬 인터내셔널 리미티드 | 면역 자극인자를 이용한 암의 치료 |
-
2015
- 2015-10-21 KR KR1020177011825A patent/KR102589557B1/ko active IP Right Grant
- 2015-10-21 JP JP2017519663A patent/JP6821560B2/ja active Active
- 2015-10-21 MX MX2017005134A patent/MX2017005134A/es unknown
- 2015-10-21 RU RU2017117194A patent/RU2740288C2/ru active
- 2015-10-21 SG SG11201702558VA patent/SG11201702558VA/en unknown
- 2015-10-21 ES ES15852092T patent/ES2882080T3/es active Active
- 2015-10-21 EP EP15852092.4A patent/EP3209321B1/en active Active
- 2015-10-21 TW TW104134583A patent/TWI683667B/zh active
- 2015-10-21 EP EP21178724.7A patent/EP3943101A1/en active Pending
- 2015-10-21 WO PCT/US2015/056609 patent/WO2016064969A1/en active Application Filing
- 2015-10-21 RU RU2020142556A patent/RU2020142556A/ru unknown
- 2015-10-21 TW TW108147603A patent/TWI749433B/zh active
- 2015-10-21 CA CA2962451A patent/CA2962451C/en active Active
- 2015-10-21 AU AU2015335979A patent/AU2015335979B2/en active Active
- 2015-10-21 CN CN201580057457.9A patent/CN107148279B/zh active Active
- 2015-10-21 BR BR112017007817A patent/BR112017007817A2/pt active Search and Examination
- 2015-10-21 US US14/918,675 patent/US9724395B2/en active Active
- 2015-10-21 CN CN202111207032.5A patent/CN113855806A/zh active Pending
-
2017
- 2017-03-27 ZA ZA2017/02111A patent/ZA201702111B/en unknown
- 2017-04-18 IL IL251761A patent/IL251761B/en active IP Right Grant
- 2017-07-05 US US15/641,550 patent/US20180161399A1/en not_active Abandoned
-
2020
- 2020-01-07 US US16/736,211 patent/US11571465B2/en active Active
-
2021
- 2021-01-06 JP JP2021000764A patent/JP7175334B2/ja active Active
-
2022
- 2022-12-12 US US18/064,793 patent/US20230285513A1/en active Pending
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