SG11201702558VA - Treatment of cancer with immune stimulators - Google Patents

Treatment of cancer with immune stimulators

Info

Publication number
SG11201702558VA
SG11201702558VA SG11201702558VA SG11201702558VA SG11201702558VA SG 11201702558V A SG11201702558V A SG 11201702558VA SG 11201702558V A SG11201702558V A SG 11201702558VA SG 11201702558V A SG11201702558V A SG 11201702558VA SG 11201702558V A SG11201702558V A SG 11201702558VA
Authority
SG
Singapore
Prior art keywords
cancer
treatment
immune stimulators
stimulators
immune
Prior art date
Application number
SG11201702558VA
Inventor
Robert S King
Cynthia Tuthill
Friedhelm Blobel
Original Assignee
Sciclone Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sciclone Pharmaceuticals Inc filed Critical Sciclone Pharmaceuticals Inc
Publication of SG11201702558VA publication Critical patent/SG11201702558VA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/2292Thymosin; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10Peptides having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/655Azo (—N=N—), diazo (=N2), azoxy (>N—O—N< or N(=O)—N<), azido (—N3) or diazoamino (—N=N—N<) compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/193Colony stimulating factors [CSF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/20Interleukins [IL]
    • A61K38/2013IL-2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/20Interleukins [IL]
    • A61K38/2046IL-7
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/21Interferons [IFN]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/21Interferons [IFN]
    • A61K38/212IFN-alpha
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2818Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
SG11201702558VA 2014-10-21 2015-10-21 Treatment of cancer with immune stimulators SG11201702558VA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462066862P 2014-10-21 2014-10-21
US201562215433P 2015-09-08 2015-09-08
PCT/US2015/056609 WO2016064969A1 (en) 2014-10-21 2015-10-21 Treatment of cancer with immune stimulators

Publications (1)

Publication Number Publication Date
SG11201702558VA true SG11201702558VA (en) 2017-05-30

Family

ID=55748164

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201702558VA SG11201702558VA (en) 2014-10-21 2015-10-21 Treatment of cancer with immune stimulators

Country Status (16)

Country Link
US (4) US9724395B2 (en)
EP (2) EP3209321B1 (en)
JP (2) JP6821560B2 (en)
KR (1) KR102589557B1 (en)
CN (2) CN113855806A (en)
AU (1) AU2015335979B2 (en)
BR (1) BR112017007817A2 (en)
CA (1) CA2962451C (en)
ES (1) ES2882080T3 (en)
IL (1) IL251761B (en)
MX (1) MX2017005134A (en)
RU (2) RU2020142556A (en)
SG (1) SG11201702558VA (en)
TW (2) TWI683667B (en)
WO (1) WO2016064969A1 (en)
ZA (1) ZA201702111B (en)

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RU2020142556A (en) 2014-10-21 2021-02-12 Сайклон Фармасьютикалз Интернешнл Лтд. METHOD FOR TREATING CANCER OR ITS METASTASIS WITH THYMOSIN-ALPHA PEPTIDE AND PROTEIN PROTEIN INHIBITOR OF PROGRAMMED CELL DEATH-1 (PD-1)
CA3002381A1 (en) * 2015-10-21 2017-04-27 Teclison Limited Compositions and methods for immune-mediated cancer therapy
US20200237904A1 (en) * 2017-01-26 2020-07-30 Immune Therapeutics Inc. Methods and Compositions Useful for Treating Cancer
CN109793891A (en) * 2017-11-17 2019-05-24 韩震 Application of the polypeptide compound in the adjuvant that preparation improves therapeutic antibodies curative effect and composition and preparation method thereof
WO2019149279A1 (en) * 2018-02-02 2019-08-08 科济生物医药(上海)有限公司 Combination of cellular immunotherapy
KR20200078312A (en) 2018-12-21 2020-07-01 한미약품 주식회사 Novel immune suppressing IL-2 analogs
JP2023515247A (en) 2020-03-31 2023-04-12 ハンミ ファーマシューティカル カンパニー リミテッド Novel immunologically active interleukin-2 analogues
CN111821424B (en) * 2020-07-21 2023-03-31 广东海洋大学深圳研究院 Application of thymosin and derivative thereof and medicament for treating depression
CN112023027B (en) * 2020-07-21 2023-03-14 广东海洋大学 Application of thymosin or derivative thereof and medicine for treating anhedonia type depression
AR125263A1 (en) 2021-03-31 2023-06-28 Hanmi Pharm Ind Co Ltd NEW IMMUNOSTIMULANT IL-2 ANALOG CONJUGATE AND ITS METHOD OF PREPARATION
CA3235940A1 (en) * 2021-10-21 2023-04-27 Jeffrey A. BACHA Compositions and methods for treatment of hyperproliferative, inflammatory, and immunological diseases, and infections

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HUT35524A (en) 1983-08-02 1985-07-29 Hoechst Ag Process for preparing pharmaceutical compositions containing regulatory /regulative/ peptides providing for the retarded release of the active substance
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Also Published As

Publication number Publication date
CN113855806A (en) 2021-12-31
CA2962451C (en) 2023-01-17
EP3209321A4 (en) 2018-10-31
US20180161399A1 (en) 2018-06-14
JP7175334B2 (en) 2022-11-18
US20230285513A1 (en) 2023-09-14
EP3209321B1 (en) 2021-06-23
US20160106812A1 (en) 2016-04-21
JP2021088557A (en) 2021-06-10
RU2740288C2 (en) 2021-01-12
RU2017117194A (en) 2018-11-22
IL251761A0 (en) 2017-06-29
ES2882080T3 (en) 2021-12-01
MX2017005134A (en) 2018-02-12
US9724395B2 (en) 2017-08-08
JP2018501192A (en) 2018-01-18
BR112017007817A2 (en) 2017-12-19
CA2962451A1 (en) 2016-04-28
RU2020142556A (en) 2021-02-12
IL251761B (en) 2020-09-30
JP6821560B2 (en) 2021-01-27
TWI683667B (en) 2020-02-01
EP3943101A1 (en) 2022-01-26
RU2017117194A3 (en) 2019-04-09
KR102589557B1 (en) 2023-10-16
US11571465B2 (en) 2023-02-07
US20200289618A1 (en) 2020-09-17
AU2015335979A1 (en) 2017-04-20
CN107148279B (en) 2021-09-03
WO2016064969A1 (en) 2016-04-28
TW202034946A (en) 2020-10-01
TW201615209A (en) 2016-05-01
EP3209321A1 (en) 2017-08-30
ZA201702111B (en) 2019-06-26
CN107148279A (en) 2017-09-08
KR20170070091A (en) 2017-06-21
TWI749433B (en) 2021-12-11
AU2015335979B2 (en) 2021-05-20

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