SG11201404888SA - Combinations of histone deacetylase inhibitor and pazopanib and uses thereof - Google Patents

Combinations of histone deacetylase inhibitor and pazopanib and uses thereof

Info

Publication number
SG11201404888SA
SG11201404888SA SG11201404888SA SG11201404888SA SG11201404888SA SG 11201404888S A SG11201404888S A SG 11201404888SA SG 11201404888S A SG11201404888S A SG 11201404888SA SG 11201404888S A SG11201404888S A SG 11201404888SA SG 11201404888S A SG11201404888S A SG 11201404888SA
Authority
SG
Singapore
Prior art keywords
pazopanib
combinations
histone deacetylase
deacetylase inhibitor
inhibitor
Prior art date
Application number
SG11201404888SA
Other languages
English (en)
Inventor
Sriram Balasubramanian
Tarak D Mody
Original Assignee
Pharmacyclics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacyclics Inc filed Critical Pharmacyclics Inc
Publication of SG11201404888SA publication Critical patent/SG11201404888SA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Oncology (AREA)
  • Pathology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SG11201404888SA 2012-02-17 2013-02-15 Combinations of histone deacetylase inhibitor and pazopanib and uses thereof SG11201404888SA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261600491P 2012-02-17 2012-02-17
US201261602544P 2012-02-23 2012-02-23
PCT/US2013/026462 WO2013123413A2 (en) 2012-02-17 2013-02-15 Combinations of histone deacetylase inhibitor and pazopanib and uses thereof

Publications (1)

Publication Number Publication Date
SG11201404888SA true SG11201404888SA (en) 2014-09-26

Family

ID=48984895

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201404888SA SG11201404888SA (en) 2012-02-17 2013-02-15 Combinations of histone deacetylase inhibitor and pazopanib and uses thereof

Country Status (12)

Country Link
US (1) US20150335609A1 (ja)
EP (1) EP2814493A4 (ja)
JP (1) JP2015507020A (ja)
KR (1) KR20140129164A (ja)
CN (1) CN104244952A (ja)
AU (1) AU2013221298A1 (ja)
CA (1) CA2864736A1 (ja)
HK (1) HK1204998A1 (ja)
MX (1) MX2014009892A (ja)
RU (1) RU2014137190A (ja)
SG (1) SG11201404888SA (ja)
WO (1) WO2013123413A2 (ja)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3079699A4 (en) * 2013-12-11 2017-07-19 Glaxosmithkline LLC Treating cancer with a combination of a pd-1 antagonist and a vegfr inhibitor
EP3594343B1 (en) * 2015-07-23 2021-04-21 Institut Curie Use of a combination of dbait molecule and parp inhibitors to treat cancer
WO2017053823A1 (en) * 2015-09-25 2017-03-30 Pharmacyclics Llc Treatment using hdac inhibitors and immunotherapy
CA3060509A1 (en) * 2017-04-21 2018-10-25 Federica Sotgia Targeting hypoxic cancer stem cells (cscs) with doxycycline: implications for improving anti-angiogenic therapy
JP7227777B2 (ja) * 2019-02-04 2023-02-22 キヤノン株式会社 撮像装置
KR20220018727A (ko) 2020-08-07 2022-02-15 계명대학교 산학협력단 파조파닙 또는 이의 약학적으로 허용가능한 염을 유효성분으로 함유하는 비만 예방 또는 치료용 조성물
WO2022125551A1 (en) * 2020-12-07 2022-06-16 Hht Foundation International, Inc. Method of treating hereditary hemorrhagic telangiectasia using pazopanib

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1611088B1 (en) * 2003-04-07 2009-06-17 Pharmacyclics, Inc. Hydroxamates as therapeutic agents
WO2005105094A2 (en) * 2004-04-16 2005-11-10 Smithkline Beecham Corporation Cancer treatment method
PL1954281T3 (pl) * 2005-11-29 2011-07-29 Novartis Ag Sposób leczenia raka
WO2010074936A2 (en) * 2008-12-15 2010-07-01 Eli Lilly And Company Enzastaurin for the treatment of cancer
US8603521B2 (en) * 2009-04-17 2013-12-10 Pharmacyclics, Inc. Formulations of histone deacetylase inhibitor and uses thereof
TW201206908A (en) * 2010-05-05 2012-02-16 Glaxo Wellcome Mfg Pte Ltd Pharmaceutical compositions and methods of making same
US20130296356A1 (en) * 2011-01-26 2013-11-07 Kurt R. Auger Combinations

Also Published As

Publication number Publication date
RU2014137190A (ru) 2016-04-10
AU2013221298A1 (en) 2014-08-28
HK1204998A1 (en) 2015-12-11
JP2015507020A (ja) 2015-03-05
MX2014009892A (es) 2015-02-12
US20150335609A1 (en) 2015-11-26
EP2814493A4 (en) 2015-07-22
CA2864736A1 (en) 2013-08-22
WO2013123413A2 (en) 2013-08-22
KR20140129164A (ko) 2014-11-06
CN104244952A (zh) 2014-12-24
EP2814493A2 (en) 2014-12-24

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