SG10201913485QA - Chimeric antigen receptors based on single-domain antibodies and methods of use thereof - Google Patents

Chimeric antigen receptors based on single-domain antibodies and methods of use thereof

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Publication number
SG10201913485QA
SG10201913485QA SG10201913485QA SG10201913485QA SG10201913485QA SG 10201913485Q A SG10201913485Q A SG 10201913485QA SG 10201913485Q A SG10201913485Q A SG 10201913485QA SG 10201913485Q A SG10201913485Q A SG 10201913485QA SG 10201913485Q A SG10201913485Q A SG 10201913485QA
Authority
SG
Singapore
Prior art keywords
methods
chimeric antigen
domain antibodies
antigen receptors
receptors based
Prior art date
Application number
SG10201913485QA
Inventor
Xiaohu Fan
Chuan-Chu Chou
Qiuchuan Zhuang
Pingyan Wang
Lin Wang
Lei Yang
Jiaying Hao
Original Assignee
Legend Biotech Ireland Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Legend Biotech Ireland Ltd filed Critical Legend Biotech Ireland Ltd
Publication of SG10201913485QA publication Critical patent/SG10201913485QA/en

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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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    • A61K39/461—Cellular immunotherapy characterised by the cell type used
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SG10201913485QA 2015-08-11 2016-08-10 Chimeric antigen receptors based on single-domain antibodies and methods of use thereof SG10201913485QA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201510490002 2015-08-11
CN201510733585.2A CN105384825B (en) 2015-08-11 2015-11-02 A kind of bispecific chimeric antigen receptor and its application based on single domain antibody

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SG10201913485QA true SG10201913485QA (en) 2020-02-27

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SG10201913485QA SG10201913485QA (en) 2015-08-11 2016-08-10 Chimeric antigen receptors based on single-domain antibodies and methods of use thereof
SG11201900635QA SG11201900635QA (en) 2015-08-11 2017-08-10 Chimeric antigen receptors targeting bcma and methods of use thereof

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SG11201900635QA SG11201900635QA (en) 2015-08-11 2017-08-10 Chimeric antigen receptors targeting bcma and methods of use thereof

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EP (6) EP4063397A1 (en)
JP (7) JP6859347B2 (en)
KR (5) KR20180035918A (en)
CN (8) CN105384825B (en)
AU (5) AU2016305075B2 (en)
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CA (3) CA2994579C (en)
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