US20040132101A1
(en)
|
2002-09-27 |
2004-07-08 |
Xencor |
Optimized Fc variants and methods for their generation
|
US20090010920A1
(en)
|
2003-03-03 |
2009-01-08 |
Xencor, Inc. |
Fc Variants Having Decreased Affinity for FcyRIIb
|
US20170166655A1
(en)
*
|
2004-03-26 |
2017-06-15 |
Xencor, Inc. |
Novel immunoglobulin variants
|
US8367805B2
(en)
|
2004-11-12 |
2013-02-05 |
Xencor, Inc. |
Fc variants with altered binding to FcRn
|
CN102746404B
(en)
|
2004-11-12 |
2016-01-20 |
赞科股份有限公司 |
To FcRn in conjunction with reformed Fc variant
|
US9493578B2
(en)
|
2009-09-02 |
2016-11-15 |
Xencor, Inc. |
Compositions and methods for simultaneous bivalent and monovalent co-engagement of antigens
|
JP5953303B2
(en)
|
2010-07-29 |
2016-07-20 |
ゼンコア インコーポレイテッド |
Antibodies with modified isoelectric points
|
JP5878182B2
(en)
|
2011-02-10 |
2016-03-08 |
ロシュ グリクアート アーゲー |
Mutant interleukin-2 polypeptide
|
DK2691417T3
(en)
|
2011-03-29 |
2018-11-19 |
Roche Glycart Ag |
ANTIBODY FC VARIANTS
|
US10654916B2
(en)
|
2011-04-21 |
2020-05-19 |
The Regents Of The University Of California, A California Corporation |
Compositions and methods for the treatment of neuromyelitis optica
|
EA201892619A1
(en)
|
2011-04-29 |
2019-04-30 |
Роше Гликарт Аг |
IMMUNOCONJUGATES CONTAINING INTERLEUKIN-2 MUTANT POLYPETIPS
|
US10400029B2
(en)
|
2011-06-28 |
2019-09-03 |
Inhibrx, Lp |
Serpin fusion polypeptides and methods of use thereof
|
PT2726092T
(en)
|
2011-06-28 |
2019-10-08 |
Lp Inhibrx |
Serpin fusion polypeptides and methods of use thereof
|
JP6159724B2
(en)
|
2011-08-23 |
2017-07-05 |
ロシュ グリクアート アーゲー |
Bispecific antibodies and tumor antigens specific for T cell activating antigens and methods of use
|
US10851178B2
(en)
|
2011-10-10 |
2020-12-01 |
Xencor, Inc. |
Heterodimeric human IgG1 polypeptides with isoelectric point modifications
|
JP6152120B2
(en)
*
|
2012-02-15 |
2017-06-21 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
Affinity chromatography based on Fc receptors
|
PL3495387T3
(en)
|
2012-07-13 |
2022-01-10 |
Roche Glycart Ag |
Bispecific anti-vegf/anti-ang-2 antibodies and their use in the treatment of ocular vascular diseases
|
CA2876099A1
(en)
*
|
2012-08-02 |
2014-02-06 |
F. Hoffmann-La Roche Ag |
Method for producing monomeric and multimeric molecules and uses thereof
|
SG11201407580YA
(en)
|
2012-08-07 |
2014-12-30 |
Roche Glycart Ag |
Composition comprising two antibodies engineered to have reduced and increased effector function
|
WO2014023673A1
(en)
|
2012-08-08 |
2014-02-13 |
Roche Glycart Ag |
Interleukin-10 fusion proteins and uses thereof
|
US20140044675A1
(en)
|
2012-08-10 |
2014-02-13 |
Roche Glycart Ag |
Interleukin-2 fusion proteins and uses thereof
|
BR112015007120A2
(en)
|
2012-10-08 |
2017-12-12 |
Roche Glycart Ag |
bispecific antibody, pharmaceutical composition, use, host cell and method of producing an antibody
|
US10487155B2
(en)
|
2013-01-14 |
2019-11-26 |
Xencor, Inc. |
Heterodimeric proteins
|
US11053316B2
(en)
|
2013-01-14 |
2021-07-06 |
Xencor, Inc. |
Optimized antibody variable regions
|
US10968276B2
(en)
|
2013-03-12 |
2021-04-06 |
Xencor, Inc. |
Optimized anti-CD3 variable regions
|
US9605084B2
(en)
|
2013-03-15 |
2017-03-28 |
Xencor, Inc. |
Heterodimeric proteins
|
KR102211837B1
(en)
|
2013-01-14 |
2021-02-03 |
젠코어 인코포레이티드 |
Novel heterodimeric proteins
|
US9701759B2
(en)
|
2013-01-14 |
2017-07-11 |
Xencor, Inc. |
Heterodimeric proteins
|
US10131710B2
(en)
|
2013-01-14 |
2018-11-20 |
Xencor, Inc. |
Optimized antibody variable regions
|
US9738722B2
(en)
|
2013-01-15 |
2017-08-22 |
Xencor, Inc. |
Rapid clearance of antigen complexes using novel antibodies
|
TWI635098B
(en)
|
2013-02-01 |
2018-09-11 |
再生元醫藥公司 |
Antibodies comprising chimeric constant domains
|
EP2762497A1
(en)
|
2013-02-05 |
2014-08-06 |
EngMab AG |
Bispecific antibodies against CD3epsilon and BCMA
|
EP2762496A1
(en)
|
2013-02-05 |
2014-08-06 |
EngMab AG |
Method for the selection of antibodies against BCMA
|
EP2953972B1
(en)
|
2013-02-05 |
2020-07-08 |
EngMab Sàrl |
Method for the selection of antibodies against bcma
|
JP2016507555A
(en)
*
|
2013-02-06 |
2016-03-10 |
インヒブルクス エルピー |
Non-platelet and non-erythrocyte-reducing CD47 antibodies and methods of use thereof
|
MX2015010350A
(en)
|
2013-02-26 |
2015-10-29 |
Roche Glycart Ag |
Bispecific t cell activating antigen binding molecules.
|
EA201891502A1
(en)
*
|
2013-02-26 |
2018-12-28 |
Роше Гликарт Аг |
BISPECIFIC ANTIGENSIVE-BONDING MOLECULES ACTIVATING T-CELLS
|
CN104936985A
(en)
|
2013-02-26 |
2015-09-23 |
罗切格利卡特公司 |
Bispecific T cell activating antigen binding molecules
|
SG10201912956YA
(en)
|
2013-03-13 |
2020-02-27 |
Genzyme Corp |
Fusion proteins comprising pdgf and vegf binding portions and methods of using thereof
|
US10858417B2
(en)
|
2013-03-15 |
2020-12-08 |
Xencor, Inc. |
Heterodimeric proteins
|
US10106624B2
(en)
|
2013-03-15 |
2018-10-23 |
Xencor, Inc. |
Heterodimeric proteins
|
US10519242B2
(en)
|
2013-03-15 |
2019-12-31 |
Xencor, Inc. |
Targeting regulatory T cells with heterodimeric proteins
|
DK2970486T3
(en)
|
2013-03-15 |
2018-08-06 |
Xencor Inc |
MODULATION OF T-CELLS WITH BISPECIFIC ANTIBODIES AND FC-FUSIONS
|
EP2971042B1
(en)
|
2013-03-15 |
2020-01-15 |
Dana-Farber Cancer Institute, Inc. |
Flavivirus neutralizing antibodies and methods of use thereof
|
UA118028C2
(en)
|
2013-04-03 |
2018-11-12 |
Рош Глікарт Аг |
Bispecific antibodies specific for fap and dr5, antibodies specific for dr5 and methods of use
|
PL2992012T3
(en)
|
2013-04-29 |
2019-12-31 |
F. Hoffmann-La Roche Ag |
Human fcrn-binding modified antibodies and methods of use
|
RU2019108429A
(en)
*
|
2013-04-29 |
2019-05-06 |
Ф. Хоффманн-Ля Рош Аг |
MODIFIED ASYMMETRIC ANTIBODIES CONNECTING FC-RECEPTOR AND METHODS OF THEIR APPLICATION
|
SG11201509566RA
(en)
*
|
2013-05-20 |
2015-12-30 |
Genentech Inc |
Anti-transferrin receptor antibodies and methods of use
|
BR112015029788B1
(en)
|
2013-05-31 |
2024-01-02 |
Zymeworks Inc |
HETERO-MULTIMER, USE AND METHOD FOR PREPARING THE SAME, PHARMACEUTICAL COMPOSITION AND METHOD FOR REDUCING EFFECTOR FUNCTION OF AN IgG FC CONSTRUCT
|
AR097584A1
(en)
|
2013-09-12 |
2016-03-23 |
Hoffmann La Roche |
ANTIBODY COMBINATION THERAPY AGAINST HUMAN CSF-1R AND ANTIBODIES AGAINST HUMAN PD-L1
|
MX2016003292A
(en)
|
2013-09-13 |
2016-06-24 |
Beigene Ltd |
Anti-pd1 antibodies and their use as therapeutics and diagnostics.
|
CN105940113A
(en)
|
2013-11-13 |
2016-09-14 |
酵活有限公司 |
Monovalent antigen binding constructs targeting egfr and/or her2 and uses thereof
|
CN105980409B
(en)
|
2013-11-27 |
2023-07-18 |
酵活生物制药有限公司 |
Bispecific antigen binding constructs targeting HER2
|
MX2016006741A
(en)
*
|
2013-12-10 |
2016-08-12 |
Hoffmann La Roche |
Use of the binding domain of a subunit of a multi-subunit structure for targeted delivery of pharmaceutically active entities to the multi-subunit structure.
|
PL3083689T3
(en)
|
2013-12-17 |
2020-10-19 |
Genentech, Inc. |
Anti-cd3 antibodies and methods of use
|
WO2015091144A1
(en)
|
2013-12-20 |
2015-06-25 |
F. Hoffmann-La Roche Ag |
Improved recombinant polypeptide production methods
|
CN111057151B
(en)
*
|
2014-01-06 |
2022-05-03 |
豪夫迈·罗氏有限公司 |
Monovalent blood brain barrier shuttle modules
|
MX2016008782A
(en)
|
2014-01-15 |
2016-09-08 |
Hoffmann La Roche |
Fc-region variants with improved protein a-binding.
|
CN106061997A
(en)
*
|
2014-02-06 |
2016-10-26 |
豪夫迈·罗氏有限公司 |
Interleukine 10 immunoconjugates
|
MX370283B
(en)
|
2014-02-06 |
2019-12-09 |
Hoffmann La Roche |
Interleukin-2 fusion proteins and uses thereof.
|
TWI701042B
(en)
|
2014-03-19 |
2020-08-11 |
美商再生元醫藥公司 |
Methods and antibody compositions for tumor treatment
|
AU2015237184B2
(en)
|
2014-03-28 |
2020-11-26 |
Xencor, Inc. |
Bispecific antibodies that bind to CD38 and CD3
|
JP6526189B2
(en)
|
2014-07-03 |
2019-06-05 |
ベイジーン リミテッド |
Anti-PD-L1 antibodies and their use for therapy and diagnosis
|
KR102524920B1
(en)
|
2014-07-22 |
2023-04-25 |
아폴로믹스 인코포레이티드 |
Anti-pd-1 antibodies
|
EP2982692A1
(en)
|
2014-08-04 |
2016-02-10 |
EngMab AG |
Bispecific antibodies against CD3epsilon and BCMA
|
KR102317315B1
(en)
|
2014-08-04 |
2021-10-27 |
에프. 호프만-라 로슈 아게 |
Bispecific t cell activating antigen binding molecules
|
MX2017001597A
(en)
|
2014-08-05 |
2017-11-17 |
Cb Therapeutics Inc |
Anti-pd-l1 antibodies.
|
KR20170052600A
(en)
|
2014-09-12 |
2017-05-12 |
제넨테크, 인크. |
Cysteine engineered antibodies and conjugates
|
WO2016040868A1
(en)
|
2014-09-12 |
2016-03-17 |
Genentech, Inc. |
Anti-cll-1 antibodies and immunoconjugates
|
MY186334A
(en)
|
2014-09-12 |
2021-07-12 |
Genentech Inc |
Anti-her2 antibodies and immunoconjugates
|
CA2957148A1
(en)
|
2014-09-17 |
2016-03-24 |
Genentech, Inc. |
Immunoconjugates comprising anti-her2 antibodies and pyrrolobenzodiazepines
|
US9938522B2
(en)
|
2014-09-25 |
2018-04-10 |
Genewiz, Inc. |
High throughput sequencing of end regions of long linear DNAs
|
US11952421B2
(en)
|
2014-10-09 |
2024-04-09 |
Bristol-Myers Squibb Company |
Bispecific antibodies against CD3EPSILON and ROR1
|
EP3212290A4
(en)
*
|
2014-10-27 |
2019-01-23 |
Inhibrx LP |
Serpin fusion polypeptides and methods of use thereof
|
US20160130324A1
(en)
*
|
2014-10-31 |
2016-05-12 |
Shire Human Genetic Therapies, Inc. |
C1 Inhibitor Fusion Proteins and Uses Thereof
|
EP3215853B1
(en)
*
|
2014-11-05 |
2022-11-16 |
F. Hoffmann-La Roche AG |
Method for the determination of anti-drug antibodies against an effector function suppressed human or humanized drug antibody
|
JP6707090B2
(en)
|
2014-11-06 |
2020-06-10 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
Fc region variants with altered FcRn binding and methods of use
|
RS61870B1
(en)
|
2014-11-14 |
2021-06-30 |
Hoffmann La Roche |
Antigen binding molecules comprising a tnf family ligand trimer
|
HUE050831T2
(en)
|
2014-11-17 |
2021-01-28 |
Regeneron Pharma |
Methods for tumor treatment using cd3xcd20 bispecific antibody
|
JP6993228B2
(en)
|
2014-11-19 |
2022-03-03 |
ジェネンテック, インコーポレイテッド |
Anti-transferrin receptor / anti-BACE1 multispecific antibody and usage
|
JP6779876B2
(en)
|
2014-11-19 |
2020-11-04 |
ジェネンテック, インコーポレイテッド |
Anti-transferrin receptor antibody and how to use it
|
ES2835823T3
(en)
|
2014-11-20 |
2021-06-23 |
Hoffmann La Roche |
Combination of T-cell activating bispecific antigen-binding molecules for CD3 and folate receptor 1 (FolR1) and PD-1 axis-binding antagonists
|
EP3023437A1
(en)
|
2014-11-20 |
2016-05-25 |
EngMab AG |
Bispecific antibodies against CD3epsilon and BCMA
|
US10259887B2
(en)
|
2014-11-26 |
2019-04-16 |
Xencor, Inc. |
Heterodimeric antibodies that bind CD3 and tumor antigens
|
CN107406512A
(en)
|
2014-11-26 |
2017-11-28 |
Xencor公司 |
With reference to CD3 and CD38 heterodimeric antibodies
|
MY184268A
(en)
|
2014-11-26 |
2021-03-30 |
Xencor Inc |
Heterodimeric antibodies that bind cd3 and tumor antigens
|
EP3029068A1
(en)
|
2014-12-03 |
2016-06-08 |
EngMab AG |
Bispecific antibodies against CD3epsilon and BCMA for use in the treatment of diseases
|
JP6738348B2
(en)
|
2014-12-19 |
2020-08-12 |
リジェネサンス ベスローテン フェンノートシャップ |
Antibodies that bind to human C6 and uses thereof
|
US10428155B2
(en)
|
2014-12-22 |
2019-10-01 |
Xencor, Inc. |
Trispecific antibodies
|
MA41459A
(en)
|
2015-02-03 |
2017-12-12 |
Als Therapy Development Inst |
ANTI-CD40L ANTIBODIES AND METHODS FOR TREATING CD40L ILLNESSES OR DISORDERS
|
US10227411B2
(en)
|
2015-03-05 |
2019-03-12 |
Xencor, Inc. |
Modulation of T cells with bispecific antibodies and FC fusions
|
US10316078B2
(en)
|
2015-03-17 |
2019-06-11 |
Agency For Science, Technology And Research |
Serotype cross-reactive, dengue neutralizing antibody and uses thereof
|
WO2016161010A2
(en)
|
2015-03-30 |
2016-10-06 |
Regeneron Pharmaceuticals, Inc. |
Heavy chain constant regions with reduced binding to fc gamma receptors
|
EP3973980A1
(en)
|
2015-03-31 |
2022-03-30 |
F. Hoffmann-La Roche AG |
Antigen binding molecules comprising a trimeric tnf family ligand
|
CA2981183A1
(en)
*
|
2015-04-07 |
2016-10-13 |
Greg Lazar |
Antigen binding complex having agonistic activity and methods of use
|
US10259882B2
(en)
|
2015-05-07 |
2019-04-16 |
Agenus Inc. |
Anti-OX40 antibodies
|
JP6963508B2
(en)
*
|
2015-05-11 |
2021-11-10 |
ジェネンテック, インコーポレイテッド |
Compositions and Methods for Treating Lupus Nephritis
|
JP6996983B2
(en)
|
2015-06-16 |
2022-02-21 |
ジェネンテック, インコーポレイテッド |
Anti-CLL-1 antibody and how to use
|
FI3310814T3
(en)
|
2015-06-16 |
2023-09-21 |
Hoffmann La Roche |
Humanized and affinity matured antibodies to fcrh5 and methods of use
|
CN107849145B
(en)
|
2015-06-16 |
2021-10-26 |
基因泰克公司 |
anti-CD 3 antibodies and methods of use thereof
|
JP2018524312A
(en)
|
2015-06-17 |
2018-08-30 |
ジェネンテック, インコーポレイテッド |
Anti-HER2 antibody and method of use
|
IL302486A
(en)
|
2015-06-24 |
2023-06-01 |
Hoffmann La Roche |
Anti-transferrin receptor antibodies with tailored affinity
|
CN108026172B
(en)
*
|
2015-06-26 |
2022-04-29 |
赛诺菲生物技术公司 |
Monoclonal anti-IL-1 RACP antibodies
|
CN107922500A
(en)
|
2015-06-29 |
2018-04-17 |
洛克菲勒大学 |
The anti-CD 40 antibodies of agonist activity with enhancing
|
KR20180042271A
(en)
|
2015-08-03 |
2018-04-25 |
잉맵 에스에이알엘 |
Monoclonal antibody corresponding to BCMA
|
EP3913051A1
(en)
|
2015-08-07 |
2021-11-24 |
ALX Oncology Inc. |
Constructs having a sirp-alpha domain or variant thereof
|
AR106188A1
(en)
|
2015-10-01 |
2017-12-20 |
Hoffmann La Roche |
ANTI-CD19 HUMANIZED HUMAN ANTIBODIES AND METHODS OF USE
|
WO2017055385A1
(en)
|
2015-10-02 |
2017-04-06 |
F. Hoffmann-La Roche Ag |
Anti-cd3xgd2 bispecific t cell activating antigen binding molecules
|
WO2017055393A1
(en)
|
2015-10-02 |
2017-04-06 |
F. Hoffmann-La Roche Ag |
Anti-cd3xtim-3 bispecific t cell activating antigen binding molecules
|
AR106189A1
(en)
|
2015-10-02 |
2017-12-20 |
Hoffmann La Roche |
BIESPECTIFIC ANTIBODIES AGAINST HUMAN A-b AND THE HUMAN TRANSFERRINE RECEIVER AND METHODS OF USE
|
AU2016329120B2
(en)
*
|
2015-10-02 |
2023-04-13 |
F. Hoffmann-La Roche Ag |
Bispecific antibodies specific for a costimulatory TNF receptor
|
TWI747843B
(en)
|
2015-10-02 |
2021-12-01 |
瑞士商赫孚孟拉羅股份公司 |
Bispecific anti-human cd20/human transferrin receptor antibodies and methods of use
|
CN108137699B
(en)
|
2015-10-02 |
2022-05-27 |
豪夫迈·罗氏有限公司 |
Bispecific antibodies specific for PD1 and TIM3
|
KR20180073561A
(en)
|
2015-10-02 |
2018-07-02 |
에프. 호프만-라 로슈 아게 |
Double specific anti-CEAXCD3 T cell activating antigen binding molecules
|
AR106365A1
(en)
|
2015-10-02 |
2018-01-10 |
Hoffmann La Roche |
BISPECIFIC MOLECULES OF ANTIGEN BINDING TO T-CELL ACTIVATORS
|
CN108026177B
(en)
|
2015-10-02 |
2021-11-26 |
豪夫迈·罗氏有限公司 |
Bispecific anti-CD 19XCD 3T cell activating antigen binding molecules
|
MX2018003827A
(en)
*
|
2015-10-02 |
2018-06-22 |
Hoffmann La Roche |
Anti-human cd19 antibodies with high affinity.
|
WO2017055392A1
(en)
|
2015-10-02 |
2017-04-06 |
F. Hoffmann-La Roche Ag |
Anti-cd3xcd44v6 bispecific t cell activating antigen binding molecules
|
MA43018B1
(en)
*
|
2015-10-02 |
2021-11-30 |
Hoffmann La Roche |
Anti-pd1 antibodies and methods of use
|
MA43345A
(en)
|
2015-10-02 |
2018-08-08 |
Hoffmann La Roche |
PYRROLOBENZODIAZEPINE ANTIBODY-DRUG CONJUGATES AND METHODS OF USE
|
US20170096495A1
(en)
|
2015-10-02 |
2017-04-06 |
Hoffmann-La Roche Inc. |
Bispecific t cell activating antigen binding molecules
|
US20180282410A1
(en)
|
2015-10-02 |
2018-10-04 |
Hoffmann-La Roche Inc. |
Anti-cd3xrob04 bispecific t cell activating antigen binding molecules
|
CR20180171A
(en)
|
2015-10-07 |
2018-05-03 |
Hoffmann La Roche |
BIESPECTIFIC ANTIBODIES WITH TETRAVALENCE FOR A FNT CO-STIMULATOR RECEIVER
|
MA43354A
(en)
|
2015-10-16 |
2018-08-22 |
Genentech Inc |
CONJUGATE DRUG CONJUGATES WITH CLOUDY DISULPHIDE
|
MA45326A
(en)
|
2015-10-20 |
2018-08-29 |
Genentech Inc |
CALICHEAMICIN-ANTIBODY-DRUG CONJUGATES AND METHODS OF USE
|
WO2017075173A2
(en)
|
2015-10-30 |
2017-05-04 |
Genentech, Inc. |
Anti-factor d antibodies and conjugates
|
MX2018005517A
(en)
|
2015-11-02 |
2018-11-09 |
Five Prime Therapeutics Inc |
Cd80 extracellular domain polypeptides and their use in cancer treatment.
|
EP3165536A1
(en)
|
2015-11-09 |
2017-05-10 |
Ludwig-Maximilians-Universität München |
Trispecific molecule combining specific tumor targeting and local immune checkpoint inhibition
|
KR20180083944A
(en)
|
2015-12-02 |
2018-07-23 |
아게누스 인코포레이티드 |
Antibodies and methods for their use
|
CN108699136B
(en)
|
2015-12-07 |
2022-03-18 |
Xencor股份有限公司 |
Heterodimeric antibodies that bind CD3 and PSMA
|
CN108290954B
(en)
|
2015-12-09 |
2022-07-26 |
豪夫迈·罗氏有限公司 |
Use of type II anti-CD 20 antibodies to reduce anti-drug antibody formation
|
EP3178848A1
(en)
|
2015-12-09 |
2017-06-14 |
F. Hoffmann-La Roche AG |
Type ii anti-cd20 antibody for reducing formation of anti-drug antibodies
|
CN106939047B
(en)
*
|
2016-01-04 |
2021-08-31 |
江苏怀瑜药业有限公司 |
PD-L1 antibody and preparation method thereof
|
KR20180101483A
(en)
|
2016-01-08 |
2018-09-12 |
에임 쎄라퓨틱스 비.브이. |
Therapeutic anti-CD9 antibody
|
CN108368179B
(en)
|
2016-01-08 |
2022-08-23 |
豪夫迈·罗氏有限公司 |
Methods of treating CEA positive cancers using PD-1 axis binding antagonists and anti-CEA/anti-CD 3 bispecific antibodies
|
CN108699155B
(en)
*
|
2016-03-01 |
2023-03-21 |
豪夫迈·罗氏有限公司 |
Orabituzumab variants with altered cell death induction
|
SG11201808085WA
(en)
|
2016-03-22 |
2018-10-30 |
Hoffmann La Roche |
Protease-activated t cell bispecific molecules
|
SI3433280T1
(en)
|
2016-03-22 |
2023-07-31 |
F. Hoffmann-La Roche Ag |
Protease-activated t cell bispecific molecules
|
EP3231813A1
(en)
|
2016-03-29 |
2017-10-18 |
F. Hoffmann-La Roche AG |
Trimeric costimulatory tnf family ligand-containing antigen binding molecules
|
MA45328A
(en)
|
2016-04-01 |
2019-02-06 |
Avidity Biosciences Llc |
NUCLEIC ACID-POLYPEPTIDE COMPOSITIONS AND USES THEREOF
|
AU2017252233A1
(en)
|
2016-04-22 |
2018-11-15 |
Alligator Bioscience Ab |
Novel bispecific polypeptides against CD137
|
CN109071652B
(en)
|
2016-05-11 |
2022-09-23 |
豪夫迈·罗氏有限公司 |
Antigen binding molecules comprising TNF family ligand trimers and tenascin binding modules
|
WO2017194441A1
(en)
|
2016-05-11 |
2017-11-16 |
F. Hoffmann-La Roche Ag |
Modified anti-tenascin antibodies and methods of use
|
EP3243836A1
(en)
|
2016-05-11 |
2017-11-15 |
F. Hoffmann-La Roche AG |
C-terminally fused tnf family ligand trimer-containing antigen binding molecules
|
EP3243832A1
(en)
|
2016-05-13 |
2017-11-15 |
F. Hoffmann-La Roche AG |
Antigen binding molecules comprising a tnf family ligand trimer and pd1 binding moiety
|
EP3458101B1
(en)
|
2016-05-20 |
2020-12-30 |
H. Hoffnabb-La Roche Ag |
Protac antibody conjugates and methods of use
|
US20170370906A1
(en)
|
2016-05-27 |
2017-12-28 |
Genentech, Inc. |
Bioanalytical analysis of site-specific antibody drug conjugates
|
EP3252078A1
(en)
|
2016-06-02 |
2017-12-06 |
F. Hoffmann-La Roche AG |
Type ii anti-cd20 antibody and anti-cd20/cd3 bispecific antibody for treatment of cancer
|
CN109476648B
(en)
|
2016-06-06 |
2022-09-13 |
豪夫迈·罗氏有限公司 |
Sevelamer antibody-drug conjugates and methods of use
|
CN109311851B
(en)
|
2016-06-12 |
2021-08-10 |
豪夫迈·罗氏有限公司 |
Dihydro pyrimidinyl benzazepine carboxamide compounds
|
EP4257613A3
(en)
|
2016-06-14 |
2023-12-13 |
Xencor, Inc. |
Bispecific checkpoint inhibitor antibodies
|
JP7021127B2
(en)
|
2016-06-28 |
2022-02-16 |
ゼンコア インコーポレイテッド |
Heterodimer antibody that binds to somatostatin receptor 2
|
GB201611530D0
(en)
|
2016-07-01 |
2016-08-17 |
Alligator Bioscience Ab |
Novel polypeptides
|
CN109475536B
(en)
|
2016-07-05 |
2022-05-27 |
百济神州有限公司 |
Combination of a PD-l antagonist and a RAF inhibitor for the treatment of cancer
|
RU2656181C1
(en)
*
|
2016-07-13 |
2018-05-31 |
Закрытое Акционерное Общество "Биокад" |
Anti-pd-1 antibodies, method for their production, and method of application
|
AU2017325654A1
(en)
|
2016-08-02 |
2019-02-14 |
Visterra, Inc. |
Engineered polypeptides and uses thereof
|
EP3494139B1
(en)
|
2016-08-05 |
2022-01-12 |
F. Hoffmann-La Roche AG |
Multivalent and multiepitopic anitibodies having agonistic activity and methods of use
|
US10696722B2
(en)
|
2016-08-10 |
2020-06-30 |
Ajou University Industry-Academic Cooperation Foundation |
Heterodimeric Fc-fused cytokine and pharmaceutical composition comprising the same
|
EP3496763A1
(en)
|
2016-08-11 |
2019-06-19 |
Genentech, Inc. |
Pyrrolobenzodiazepine prodrugs and antibody conjugates thereof
|
AU2017313085A1
(en)
|
2016-08-19 |
2019-03-14 |
Beigene Switzerland Gmbh |
Use of a combination comprising a Btk inhibitor for treating cancers
|
EP3504239A1
(en)
|
2016-08-25 |
2019-07-03 |
H. Hoffnabb-La Roche Ag |
Intermittent dosing of an anti-csf-1r antibody in combination with macrophage activating agent
|
US10793632B2
(en)
|
2016-08-30 |
2020-10-06 |
Xencor, Inc. |
Bispecific immunomodulatory antibodies that bind costimulatory and checkpoint receptors
|
JP7022123B2
(en)
|
2016-09-30 |
2022-02-17 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
Bispecific antibody against CD3
|
CN110139674B
(en)
|
2016-10-05 |
2023-05-16 |
豪夫迈·罗氏有限公司 |
Method for preparing antibody drug conjugates
|
WO2018071919A1
(en)
|
2016-10-14 |
2018-04-19 |
Xencor, Inc. |
IL15/IL15Rα HETERODIMERIC FC-FUSION PROTEINS
|
JP7277363B2
(en)
|
2016-11-01 |
2023-05-18 |
ジェンマブ ビー.ブイ. |
Polypeptide variants and uses thereof
|
CA3041183A1
(en)
|
2016-11-02 |
2018-05-11 |
Engmab Sarl |
Bispecific antibody against bcma and cd3 and an immunological drug for combined use in treating multiple myeloma
|
AU2017359467A1
(en)
|
2016-11-09 |
2019-05-02 |
Agenus Inc. |
Anti-OX40 antibodies, anti-GITR antibodies, and methods of use thereof
|
KR20190074300A
(en)
|
2016-11-15 |
2019-06-27 |
제넨테크, 인크. |
Dosage for treatment with anti-CD20 / anti-CD3 bispecific antibodies
|
TW201829463A
(en)
*
|
2016-11-18 |
2018-08-16 |
瑞士商赫孚孟拉羅股份公司 |
Anti-hla-g antibodies and use thereof
|
MA50948A
(en)
|
2016-12-07 |
2020-10-14 |
Agenus Inc |
ANTIBODIES AND METHODS OF USING THE SAME
|
CA3045495A1
(en)
|
2016-12-12 |
2018-06-21 |
Genentech, Inc. |
Methods of treating cancer using anti-pd-l1 antibodies and antiandrogens
|
IL267284B2
(en)
|
2016-12-19 |
2023-03-01 |
Hoffmann La Roche |
Combination therapy with targeted 4-1bb (cd137) agonists
|
KR20190093588A
(en)
|
2016-12-20 |
2019-08-09 |
에프. 호프만-라 로슈 아게 |
Combination therapy of anti-CD20 / anti-CD3 bispecific antibodies and 4-1BB (CD137) agonists
|
EP3558360A1
(en)
|
2016-12-22 |
2019-10-30 |
F. Hoffmann-La Roche AG |
Treatment of tumors with an anti-csf-1r antibody in combination with an anti-pd-l1 antibody after failure of anti-pd-l1/pd1 treatment
|
EP3565843A1
(en)
|
2017-01-03 |
2019-11-13 |
H. Hoffnabb-La Roche Ag |
Bispecific antigen binding molecules comprising anti-4-1bb clone 20h4.9
|
SG11201906200WA
(en)
|
2017-01-06 |
2019-08-27 |
Avidity Biosciences Llc |
Nucleic acid-polypeptide compositions and methods of inducing exon skipping
|
TWI787230B
(en)
|
2017-01-20 |
2022-12-21 |
法商賽諾菲公司 |
Anti-tgf-beta antibodies and their use
|
EP3573989A4
(en)
|
2017-01-25 |
2020-11-18 |
Beigene, Ltd. |
Crystalline forms of (s) -7- (1- (but-2-ynoyl) piperidin-4-yl) -2- (4-phenoxyphenyl) -4, 5, 6, 7-tetrahy dropyrazolo [1, 5-a]pyrimidine-3-carboxamide, preparation, and uses thereof
|
BR112019020168A2
(en)
|
2017-03-27 |
2020-06-02 |
F. Hoffmann-La Roche Ag |
ANTIGEN BINDING RECEPTORS, TRANSDUCTED T CELLS, ISOLATED POLYNUCLEOTIDE, VECTOR, KITS, METHODS FOR TREATING A DISEASE AND INDUCING THE LYING OF A TARGET CELL AND USE OF THE ANTIGEN BINDING RECEPTOR
|
CR20190431A
(en)
|
2017-03-27 |
2019-11-01 |
Hoffmann La Roche |
Improved antigen binding receptor formats
|
WO2018178076A1
(en)
|
2017-03-29 |
2018-10-04 |
F. Hoffmann-La Roche Ag |
Bispecific antigen binding molecule for a costimulatory tnf receptor
|
WO2018178074A1
(en)
|
2017-03-29 |
2018-10-04 |
F. Hoffmann-La Roche Ag |
Trimeric antigen binding molecules specific for a costimulatory tnf receptor
|
CN110573528B
(en)
|
2017-03-29 |
2023-06-09 |
豪夫迈·罗氏有限公司 |
Bispecific antigen binding molecules to costimulatory TNF receptors
|
EP3606947B1
(en)
|
2017-04-03 |
2022-12-21 |
F. Hoffmann-La Roche AG |
Immunoconjugates of il-2 with an anti-pd-1 and tim-3 bispecific antibody
|
DK3606946T3
(en)
|
2017-04-03 |
2022-10-24 |
Hoffmann La Roche |
Immunoconjugates of an anti-PD-1 antibody with a mutated IL-2 or with IL-15
|
WO2018184966A1
(en)
|
2017-04-03 |
2018-10-11 |
F. Hoffmann-La Roche Ag |
Antibodies binding to steap-1
|
JP6997209B2
(en)
|
2017-04-04 |
2022-02-04 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
A novel bispecific antigen-binding molecule capable of specifically binding to CD40 and FAP
|
TWI747215B
(en)
|
2017-04-05 |
2021-11-21 |
瑞士商赫孚孟拉羅股份公司 |
Bispecific antibodies specifically binding to pd1 and lag3
|
SI3606954T1
(en)
*
|
2017-04-05 |
2022-10-28 |
F. Hoffmann - La Roche Ag |
Anti-lag3 antibodies
|
TWI788340B
(en)
|
2017-04-07 |
2023-01-01 |
美商必治妥美雅史谷比公司 |
Anti-icos agonist antibodies and uses thereof
|
WO2018189220A1
(en)
|
2017-04-13 |
2018-10-18 |
F. Hoffmann-La Roche Ag |
An interleukin-2 immunoconjugate, a cd40 agonist, and optionally a pd-1 axis binding antagonist for use in methods of treating cancer
|
WO2018191660A1
(en)
|
2017-04-14 |
2018-10-18 |
Genentech, Inc. |
Diagnostic and therapeutic methods for cancer
|
US11584790B2
(en)
*
|
2017-04-14 |
2023-02-21 |
Kodiak Sciences Inc. |
Complement factor D antagonist antibodies and conjugates thereof
|
KR20190139216A
(en)
|
2017-04-28 |
2019-12-17 |
파이브 프라임 테라퓨틱스, 인크. |
Therapeutic Methods Using CD80 Extracellular Domain Polypeptides
|
EP3401332A1
(en)
|
2017-05-08 |
2018-11-14 |
MAB Discovery GmbH |
Anti-il-1r3 antibodies for use in inflammatory conditions
|
CN110662768B
(en)
|
2017-05-24 |
2024-01-30 |
Als治疗发展学会 |
Therapeutic anti-CD 40 ligand antibodies
|
MX2019014274A
(en)
|
2017-06-02 |
2020-01-23 |
Hoffmann La Roche |
Type ii anti-cd20 antibody and anti-cd20/cd3 bispecific antibody for treatment of cancer.
|
CA3067351A1
(en)
|
2017-06-15 |
2018-12-20 |
Nai-Kong Cheung |
Anti-l1-cam antibodies and uses thereof
|
WO2018236728A1
(en)
*
|
2017-06-18 |
2018-12-27 |
Kindred Biosciences, Inc. |
Il17a antibodies and antagonists for veterinary use
|
WO2018237097A1
(en)
|
2017-06-20 |
2018-12-27 |
Amgen Inc. |
Method of treating or ameliorating metabolic disorders using binding proteins for gastric inhibitory peptide receptor (gipr) in combination with glp-1 agonists
|
AU2018290532A1
(en)
|
2017-06-26 |
2019-11-21 |
Beigene, Ltd. |
Immunotherapy for hepatocellular carcinoma
|
EP3645122A1
(en)
|
2017-06-30 |
2020-05-06 |
Xencor, Inc. |
Targeted heterodimeric fc fusion proteins containing il-15/il-15ra and antigen binding domains
|
SG11202000503QA
(en)
|
2017-07-20 |
2020-02-27 |
Aptevo Res & Development Llc |
Antigen binding proteins binding to 5t4 and 4-1bb and related compositions and methods
|
GB201711809D0
(en)
|
2017-07-21 |
2017-09-06 |
Governors Of The Univ Of Alberta |
Antisense oligonucleotide
|
JP7437301B2
(en)
|
2017-08-25 |
2024-02-22 |
ファイヴ プライム セラピューティクス インク |
B7-H4 antibody and its usage
|
AU2018323470A1
(en)
|
2017-08-28 |
2020-03-19 |
Angiex, Inc. |
Anti-TM4SF1 antibodies and methods of using same
|
US20190100587A1
(en)
*
|
2017-10-02 |
2019-04-04 |
Covagen Ag |
IgG1 Fc MUTANTS WITH ABLATED EFFECTOR FUNCTIONS
|
CN111247171A
(en)
|
2017-10-14 |
2020-06-05 |
西托姆克斯治疗公司 |
Antibodies, activatable antibodies, bispecific antibodies and bispecific activatable antibodies and methods of use thereof
|
WO2019084060A1
(en)
|
2017-10-24 |
2019-05-02 |
Silverback Therapeutics, Inc. |
Conjugates and methods of use thereof for selective delivery of immune-modulatory agents
|
WO2019086499A1
(en)
|
2017-11-01 |
2019-05-09 |
F. Hoffmann-La Roche Ag |
Novel tnf family ligand trimer-containing antigen binding molecules
|
KR20200084006A
(en)
|
2017-11-01 |
2020-07-09 |
에프. 호프만-라 로슈 아게 |
Combination therapy with targeted OX40 agonists
|
TWI829658B
(en)
|
2017-11-01 |
2024-01-21 |
瑞士商赫孚孟拉羅股份公司 |
Bispecific 2+1 contorsbodies
|
CA3082383A1
(en)
|
2017-11-08 |
2019-05-16 |
Xencor, Inc. |
Bispecific and monospecific antibodies using novel anti-pd-1 sequences
|
US10981992B2
(en)
|
2017-11-08 |
2021-04-20 |
Xencor, Inc. |
Bispecific immunomodulatory antibodies that bind costimulatory and checkpoint receptors
|
AR113696A1
(en)
|
2017-11-17 |
2020-06-03 |
Merck Sharp & Dohme |
SPECIFIC ANTIBODIES FOR IMMUNOGLOBULIN TYPE 3 (ILT3) SIMILAR TRANSCRIPT AND ITS USES
|
WO2019108795A1
(en)
|
2017-11-29 |
2019-06-06 |
Beigene Switzerland Gmbh |
Treatment of indolent or aggressive b-cell lymphomas using a combination comprising btk inhibitors
|
WO2019113393A1
(en)
|
2017-12-06 |
2019-06-13 |
Avidity Biosciences Llc |
Compositions and methods of treating muscle atrophy and myotonic dystrophy
|
KR20200100098A
(en)
|
2017-12-19 |
2020-08-25 |
젠코어 인코포레이티드 |
Engineered IL-2 FC fusion protein
|
JP7394058B2
(en)
*
|
2017-12-21 |
2023-12-07 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
Universal reporter cell assay for specificity testing of novel antigen-binding moieties
|
BR112020011469A2
(en)
|
2017-12-21 |
2020-11-24 |
F. Hoffmann-La Roche Ag |
antibodies, bispecific antigen binding molecule, one or more isolated polynucleotides, one or more vectors, host cell, method for producing an antibody, pharmaceutical composition, use of the antibody, method of treating a disease and invention
|
EP3502140A1
(en)
|
2017-12-21 |
2019-06-26 |
F. Hoffmann-La Roche AG |
Combination therapy of tumor targeted icos agonists with t-cell bispecific molecules
|
JP7436365B2
(en)
|
2017-12-29 |
2024-02-21 |
エフ. ホフマン-ラ ロシュ アーゲー |
Anti-VEGF antibodies and methods of use
|
CN108218998A
(en)
*
|
2017-12-31 |
2018-06-29 |
武汉班科生物技术股份有限公司 |
A kind of Fc segments of saltant type humanized IgG and preparation method and application
|
WO2019143636A1
(en)
|
2018-01-16 |
2019-07-25 |
Lakepharma, Inc. |
Bispecific antibody that binds cd3 and another target
|
US20210107988A1
(en)
|
2018-01-24 |
2021-04-15 |
Genmab B.V. |
Polypeptide variants and uses thereof
|
WO2019149715A1
(en)
|
2018-01-31 |
2019-08-08 |
F. Hoffmann-La Roche Ag |
Stabilized immunoglobulin domains
|
JP2021511793A
(en)
|
2018-01-31 |
2021-05-13 |
エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト |
Bispecific antibody containing an antigen binding site that binds to LAG3
|
AR115360A1
(en)
|
2018-02-08 |
2021-01-13 |
Genentech Inc |
ANTIGEN BINDING MOLECULES AND METHODS OF USE
|
TWI829667B
(en)
|
2018-02-09 |
2024-01-21 |
瑞士商赫孚孟拉羅股份公司 |
Antibodies binding to gprc5d
|
AU2019226009A1
(en)
|
2018-02-21 |
2020-09-03 |
Five Prime Therapeutics, Inc. |
B7-H4 antibody dosing regimens
|
CA3091174A1
(en)
|
2018-02-21 |
2019-08-29 |
Five Prime Therapeutics, Inc. |
B7-h4 antibody formulations
|
MX2020008882A
(en)
|
2018-02-26 |
2021-01-08 |
Genentech Inc |
Dosing for treatment with anti-tigit and anti-pd-l1 antagonist antibodies.
|
EA202091810A1
(en)
|
2018-03-02 |
2021-01-29 |
Файв Прайм Терапьютикс, Инк. |
ANTIBODIES TO B7-H4 AND METHODS OF THEIR APPLICATION
|
CA3092002A1
(en)
|
2018-03-13 |
2019-09-19 |
F. Hoffmann-La Roche Ag |
Therapeutic combination of 4-1 bb agonists with anti-cd20 antibodies
|
TW202003561A
(en)
|
2018-03-13 |
2020-01-16 |
瑞士商赫孚孟拉羅股份公司 |
Combination therapy with targeted 4-1BB (CD137) agonists
|
RS64690B1
(en)
|
2018-03-13 |
2023-11-30 |
Zymeworks Bc Inc |
Anti-her2 biparatopic antibody-drug conjugates and methods of use
|
CN110305217B
(en)
|
2018-03-27 |
2022-03-29 |
广州爱思迈生物医药科技有限公司 |
Bispecific antibodies and uses thereof
|
WO2019191552A1
(en)
|
2018-03-29 |
2019-10-03 |
Genentech, Inc. |
Modulating lactogenic activity in mammalian cells
|
US20210154188A1
(en)
|
2018-04-02 |
2021-05-27 |
Silverback Therapeutics, Inc. |
Alk5 inhibitors, conjugates, and uses thereof
|
WO2019195623A2
(en)
|
2018-04-04 |
2019-10-10 |
Xencor, Inc. |
Heterodimeric antibodies that bind fibroblast activation protein
|
SG11202007961QA
(en)
|
2018-04-13 |
2020-09-29 |
Hoffmann La Roche |
Her2-targeting antigen binding molecules comprising 4-1bbl
|
EP3781599A1
(en)
|
2018-04-18 |
2021-02-24 |
Xencor, Inc. |
Pd-1 targeted heterodimeric fusion proteins containing il-15/il-15ra fc-fusion proteins and pd-1 antigen binding domains and uses thereof
|
EP3781598A1
(en)
|
2018-04-18 |
2021-02-24 |
Xencor, Inc. |
Tim-3 targeted heterodimeric fusion proteins containing il-15/il-15ra fc-fusion proteins and tim-3 antigen binding domains
|
AR115052A1
(en)
|
2018-04-18 |
2020-11-25 |
Hoffmann La Roche |
MULTI-SPECIFIC ANTIBODIES AND THE USE OF THEM
|
CA3098486A1
(en)
|
2018-05-03 |
2019-11-07 |
Genmab B.V. |
Antibody variant combinations and uses thereof
|
EP3802518A1
(en)
|
2018-05-25 |
2021-04-14 |
Silverback Therapeutics, Inc. |
Amino-pyrazinecarboxamide compounds, conjugates, and uses thereof
|
CA3102349A1
(en)
|
2018-06-05 |
2019-12-12 |
King's College London |
Btnl3/8 targeting constructs for delivery of payloads to the gastrointestinal system
|
WO2019244107A1
(en)
|
2018-06-21 |
2019-12-26 |
Daiichi Sankyo Company, Limited |
Compositions including cd3 antigen binding fragments and uses thereof
|
EP3818082A1
(en)
|
2018-07-04 |
2021-05-12 |
F. Hoffmann-La Roche AG |
Novel bispecific agonistic 4-1bb antigen binding molecules
|
MX2021002190A
(en)
|
2018-08-31 |
2021-05-14 |
Regeneron Pharma |
Dosing strategy that mitigates cytokine release syndrome for cd3/c20 bispecific antibodies.
|
GB201814281D0
(en)
|
2018-09-03 |
2018-10-17 |
Femtogenix Ltd |
Cytotoxic agents
|
US20220048895A1
(en)
|
2018-09-12 |
2022-02-17 |
Silverback Therapeutics, Inc. |
Substituted benzazepine compounds, conjugates, and uses thereof
|
CA3111784A1
(en)
|
2018-09-12 |
2020-03-19 |
Silverback Therapeutics, Inc. |
Methods and compositions for the treatment of disease with immune stimulatory conjugates
|
EP3856788A4
(en)
*
|
2018-09-29 |
2022-07-06 |
MAB-Legend Biotech Co., Ltd. |
Dual targeting antigen binding molecule
|
CN112955468A
(en)
|
2018-10-01 |
2021-06-11 |
豪夫迈·罗氏有限公司 |
Bispecific antigen binding molecules comprising anti-FAP clone 212
|
EP3861025A1
(en)
|
2018-10-01 |
2021-08-11 |
F. Hoffmann-La Roche AG |
Bispecific antigen binding molecules with trivalent binding to cd40
|
MA53822A
(en)
|
2018-10-03 |
2021-08-11 |
Xencor Inc |
IL-12 HETERODIMER FC FUSION PROTEINS
|
JP7448552B2
(en)
|
2018-10-15 |
2024-03-12 |
ファイヴ プライム セラピューティクス インク |
Combination therapy for cancer
|
EP3870598A1
(en)
|
2018-10-23 |
2021-09-01 |
Dragonfly Therapeutics, Inc. |
Heterodimeric fc-fused proteins
|
WO2020089437A1
(en)
|
2018-10-31 |
2020-05-07 |
Engmab Sàrl |
Combination therapy
|
EP3889179A4
(en)
*
|
2018-11-01 |
2022-10-12 |
Shandong New Time Pharmaceutical Co., Ltd. |
Bispecific antibody and use thereof
|
WO2020102251A1
(en)
*
|
2018-11-14 |
2020-05-22 |
Jn Biosciences Llc |
Multimeric hybrid fc proteins for replacement of ivig
|
EP4198057A1
(en)
|
2018-12-05 |
2023-06-21 |
F. Hoffmann-La Roche AG |
Diagnostic methods and compositions for cancer immunotherapy
|
WO2020115115A1
(en)
|
2018-12-05 |
2020-06-11 |
Morphosys Ag |
Multispecific antigen-binding molecules
|
CN113227119A
(en)
|
2018-12-10 |
2021-08-06 |
基因泰克公司 |
Photocrosslinked peptides for site-specific conjugation to Fc-containing proteins
|
WO2020127376A2
(en)
|
2018-12-17 |
2020-06-25 |
Alligator Bioscience Ab |
Novel polypeptides
|
US20220064325A1
(en)
|
2018-12-17 |
2022-03-03 |
Alligator Bioscience Ab |
Novel polypeptides
|
EP3898667A2
(en)
|
2018-12-20 |
2021-10-27 |
F. Hoffmann-La Roche AG |
Modified antibody fcs and methods of use
|
AU2019406712A1
(en)
|
2018-12-21 |
2021-06-17 |
F. Hoffmann-La Roche Ag |
Antibody that binds to VEGF and IL-1beta and methods of use
|
CN113286822A
(en)
|
2018-12-21 |
2021-08-20 |
豪夫迈·罗氏有限公司 |
Tumor-targeting hyperactive CD28 antigen binding molecules
|
CR20210330A
(en)
|
2018-12-21 |
2021-07-20 |
Hoffmann La Roche |
Antibodies binding to cd3
|
US11608376B2
(en)
|
2018-12-21 |
2023-03-21 |
Hoffmann-La Roche Inc. |
Tumor-targeted agonistic CD28 antigen binding molecules
|
CN113453716A
(en)
*
|
2018-12-27 |
2021-09-28 |
金德雷德生物科学股份有限公司 |
Veterinary IgG Fc variants
|
WO2020154424A1
(en)
*
|
2019-01-22 |
2020-07-30 |
The Brigham And Women's Hospital, Inc. |
Antigen-presenting neutrophil-derived dendritic cells and methods of use thereof
|
GB201901197D0
(en)
|
2019-01-29 |
2019-03-20 |
Femtogenix Ltd |
G-A Crosslinking cytotoxic agents
|
AU2020228383A1
(en)
|
2019-02-27 |
2021-09-23 |
Genentech, Inc. |
Dosing for treatment with anti-tigit and anti-CD20 or anti-CD38 antibodies
|
CN114173875A
(en)
|
2019-03-01 |
2022-03-11 |
Xencor股份有限公司 |
Heterodimeric antibodies that bind ENPP3 and CD3
|
US20220169660A1
(en)
|
2019-03-06 |
2022-06-02 |
Silverback Therapeutics, Inc. |
Cyclic amino-pyrazinecarboxamide compounds and uses thereof
|
MX2021011040A
(en)
|
2019-03-14 |
2021-12-10 |
Morphosys Ag |
Antibodies targeting c5ar.
|
KR20210141555A
(en)
|
2019-03-14 |
2021-11-23 |
제넨테크, 인크. |
Treatment of cancer with HER2XCD3 bispecific antibody and anti-HER2 MAB in combination
|
EP3952996A1
(en)
|
2019-04-12 |
2022-02-16 |
F. Hoffmann-La Roche AG |
Bispecific antigen binding molecules comprising lipocalin muteins
|
CN114364703A
(en)
|
2019-04-19 |
2022-04-15 |
豪夫迈·罗氏有限公司 |
Anti-merk antibodies and methods of use thereof
|
KR20220044904A
(en)
|
2019-05-31 |
2022-04-12 |
알렉소 온콜로지 인크. |
How to treat cancer with SIRP alpha FC fusion in combination with immune checkpoint inhibitors
|
WO2020251834A1
(en)
*
|
2019-06-11 |
2020-12-17 |
The Rockefeller University |
Antibodies and methods for treatment of viral infections
|
JP2022536855A
(en)
|
2019-06-19 |
2022-08-19 |
シルバーバック セラピューティックス インコーポレイテッド |
Anti-mesothelin antibodies and their immunoconjugates
|
MX2021015888A
(en)
|
2019-06-26 |
2022-03-22 |
Hoffmann La Roche |
Fusion of an antibody binding cea and 4-1bbl.
|
CN114531878A
(en)
|
2019-06-27 |
2022-05-24 |
豪夫迈·罗氏有限公司 |
Novel ICOS antibodies and tumor-targeted antigen-binding molecules comprising same
|
TW202115115A
(en)
|
2019-07-02 |
2021-04-16 |
瑞士商赫孚孟拉羅股份公司 |
Immunoconjugates
|
US20220267469A1
(en)
*
|
2019-07-12 |
2022-08-25 |
Lipum Ab |
Novel bssl antibodies
|
AR119382A1
(en)
|
2019-07-12 |
2021-12-15 |
Hoffmann La Roche |
PRE-TARGETING ANTIBODIES AND METHODS OF USE
|
AR119393A1
(en)
|
2019-07-15 |
2021-12-15 |
Hoffmann La Roche |
ANTIBODIES THAT BIND NKG2D
|
EP3999501A1
(en)
|
2019-07-16 |
2022-05-25 |
Silverback Therapeutics, Inc. |
Alk5 inhibitors, conjugates, and uses thereof
|
JP2022543551A
(en)
|
2019-07-31 |
2022-10-13 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
Antibody that binds to GPRC5D
|
KR20220028035A
(en)
|
2019-07-31 |
2022-03-08 |
에프. 호프만-라 로슈 아게 |
Antibodies that bind to GPRC5D
|
AU2020331036A1
(en)
|
2019-08-15 |
2022-03-03 |
Silverback Therapeutics, Inc. |
Formulations of benzazepine conjugates and uses thereof
|
MX2022002963A
(en)
|
2019-09-12 |
2022-04-06 |
Genentech Inc |
Compositions and methods of treating lupus nephritis.
|
TW202126698A
(en)
|
2019-09-18 |
2021-07-16 |
美商建南德克公司 |
Anti-klk7 antibodies, anti-klk5 antibodies, multispecific anti-klk5/klk7 antibodies, and methods of use
|
CR20220127A
(en)
|
2019-09-27 |
2022-05-27 |
Genentech Inc |
Dosing for treatment with anti-tigit and anti-pd-l1 antagonist antibodies
|
AU2020358726A1
(en)
|
2019-10-01 |
2022-04-07 |
Silverback Therapeutics, Inc. |
Combination therapy with immune stimulatory conjugates
|
EP4017542A1
(en)
|
2019-10-04 |
2022-06-29 |
Tae Life Sciences |
Antibody compositions comprising fc mutations and site-specific conjugation properties
|
US20210130473A1
(en)
|
2019-10-09 |
2021-05-06 |
Silverback Therapeutics, Inc. |
TGFßR1 INHIBITOR-ASGR ANTIBODY CONJUGATES AND USES THEREOF
|
WO2021072265A1
(en)
|
2019-10-10 |
2021-04-15 |
Kodiak Sciences Inc. |
Methods of treating an eye disorder
|
EP4055388A1
(en)
|
2019-11-06 |
2022-09-14 |
Genentech, Inc. |
Diagnostic and therapeutic methods for treatment of hematologic cancers
|
US20220411529A1
(en)
|
2019-11-06 |
2022-12-29 |
Genmab B.V. |
Antibody variant combinations and uses thereof
|
WO2021102332A1
(en)
|
2019-11-22 |
2021-05-27 |
Silverback Therapeutics, Inc. |
Tgfbetar2 inhibitor-lrrc15 antibody conjugates and uses thereof
|
US11845799B2
(en)
|
2019-12-13 |
2023-12-19 |
Genentech, Inc. |
Anti-Ly6G6D antibodies and methods of use
|
PE20221282A1
(en)
|
2019-12-18 |
2022-09-05 |
Hoffmann La Roche |
ANTIBODIES THAT BIND HLA-A2/MAGE-A4
|
CN114846024A
(en)
|
2019-12-20 |
2022-08-02 |
豪夫迈·罗氏有限公司 |
IL-37 fusion proteins and uses thereof
|
MX2022008214A
(en)
|
2020-01-09 |
2022-08-08 |
Hoffmann La Roche |
New 4-1bbl trimer-containing antigen binding molecules.
|
TW202140553A
(en)
|
2020-01-13 |
2021-11-01 |
美商威特拉公司 |
Antibody molecules to c5ar1 and uses thereof
|
WO2021194481A1
(en)
|
2020-03-24 |
2021-09-30 |
Genentech, Inc. |
Dosing for treatment with anti-tigit and anti-pd-l1 antagonist antibodies
|
WO2022050954A1
(en)
|
2020-09-04 |
2022-03-10 |
Genentech, Inc. |
Dosing for treatment with anti-tigit and anti-pd-l1 antagonist antibodies
|
US20230126689A1
(en)
|
2020-03-06 |
2023-04-27 |
Go Therapeutics, Inc. |
Anti-glyco-cd44 antibodies and their uses
|
AU2021232158A1
(en)
|
2020-03-06 |
2022-09-29 |
Ona Therapeutics, S.L. |
Anti-CD36 antibodies and their use to treat cancer
|
EP4121063A1
(en)
|
2020-03-19 |
2023-01-25 |
Avidity Biosciences, Inc. |
Compositions and methods of treating facioscapulohumeral muscular dystrophy
|
WO2021195464A2
(en)
|
2020-03-26 |
2021-09-30 |
Genentech, Inc. |
Modified mammalian cells
|
CN115298544A
(en)
*
|
2020-03-26 |
2022-11-04 |
电化株式会社 |
Reagent containing antibody with deletion of part of Fc region
|
WO2021198034A1
(en)
|
2020-03-30 |
2021-10-07 |
F. Hoffmann-La Roche Ag |
Antibody that binds to vegf and pdgf-b and methods of use
|
AR121706A1
(en)
|
2020-04-01 |
2022-06-29 |
Hoffmann La Roche |
OX40 AND FAP-TARGETED BSPECIFIC ANTIGEN-BINDING MOLECULES
|
IL294451A
(en)
|
2020-04-15 |
2022-09-01 |
Hoffmann La Roche |
Immunoconjugates
|
US20230272041A1
(en)
|
2020-04-22 |
2023-08-31 |
Dragonfly Therapeutics, Inc. |
Formulation, Dosage Regimen, and Manufacturing Process for Heterodimeric FC-Fused Proteins
|
CN115551540A
(en)
|
2020-05-11 |
2022-12-30 |
豪夫迈·罗氏有限公司 |
Combination therapy using modified PBMCs and immunoconjugates
|
WO2021231976A1
(en)
|
2020-05-14 |
2021-11-18 |
Xencor, Inc. |
Heterodimeric antibodies that bind prostate specific membrane antigen (psma) and cd3
|
EP4149964A2
(en)
|
2020-05-15 |
2023-03-22 |
Apogenix AG |
Multi-specific immune modulators
|
IL297977A
(en)
|
2020-05-17 |
2023-01-01 |
Astrazeneca Uk Ltd |
Sars-cov-2 antibodies and methods of selecting and using the same
|
CR20220586A
(en)
|
2020-05-19 |
2023-01-09 |
Boehringer Ingelheim Int |
Binding molecules for the treatment of cancer
|
GB2595299B
(en)
|
2020-05-21 |
2022-08-03 |
Mabsolve Ltd |
Modified immunoglobulin FC regions
|
CN115803091A
(en)
|
2020-05-22 |
2023-03-14 |
福迈康股份公司 |
ACE2-FC fusion protein and application thereof
|
JP2023527918A
(en)
|
2020-06-08 |
2023-06-30 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
Anti-HBV antibody and method of use
|
EP4168118A1
(en)
|
2020-06-18 |
2023-04-26 |
Genentech, Inc. |
Treatment with anti-tigit antibodies and pd-1 axis binding antagonists
|
IL296429A
(en)
|
2020-06-19 |
2022-11-01 |
Hoffmann La Roche |
Protease-activated t cell bispecific antibodies
|
AU2021291005A1
(en)
|
2020-06-19 |
2023-01-05 |
F. Hoffmann-La Roche Ag |
Antibodies binding to CD3 and FolR1
|
AU2021291011A1
(en)
|
2020-06-19 |
2023-01-05 |
F. Hoffmann-La Roche Ag |
Antibodies binding to CD3 and CD19
|
CN115698084A
(en)
|
2020-06-19 |
2023-02-03 |
豪夫迈·罗氏有限公司 |
Antibodies that bind to CD3
|
WO2021255146A1
(en)
|
2020-06-19 |
2021-12-23 |
F. Hoffmann-La Roche Ag |
Antibodies binding to cd3 and cea
|
EP4168445A1
(en)
|
2020-06-19 |
2023-04-26 |
F. Hoffmann-La Roche AG |
Immune activating fc domain binding molecules
|
JP2023530760A
(en)
|
2020-06-23 |
2023-07-19 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
Agonist CD28 antigen-binding molecules targeting Her2
|
EP4172192A1
(en)
|
2020-06-24 |
2023-05-03 |
Genentech, Inc. |
Apoptosis resistant cell lines
|
JP2023531067A
(en)
|
2020-06-25 |
2023-07-20 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
Anti-CD3/Anti-CD28 Bispecific Antigen Binding Molecules
|
CN116249716A
(en)
|
2020-07-07 |
2023-06-09 |
康愈有限责任公司 |
MIC antibodies and binding agents and methods of use thereof
|
AU2021303508A1
(en)
|
2020-07-10 |
2023-02-02 |
F. Hoffmann-La Roche Ag |
Antibodies which bind to cancer cells and target radionuclides to said cells
|
AU2021308653A1
(en)
|
2020-07-17 |
2023-02-16 |
Genentech, Inc. |
Anti-Notch2 antibodies and methods of use
|
GB2597532A
(en)
|
2020-07-28 |
2022-02-02 |
Femtogenix Ltd |
Cytotoxic compounds
|
WO2022024034A1
(en)
|
2020-07-31 |
2022-02-03 |
Glaxosmithkline Intellectual Property Development Limited |
Antigen binding protein
|
CN116568824A
(en)
|
2020-08-03 |
2023-08-08 |
基因泰克公司 |
Method for diagnosing and treating lymphoma
|
JP2023536169A
(en)
|
2020-08-03 |
2023-08-23 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
Improved antigen binding receptor
|
KR20230045613A
(en)
|
2020-08-10 |
2023-04-04 |
아스트라제네카 유케이 리미티드 |
SARS-COV-2 Antibodies for Treatment and Prevention of COVID-19
|
KR102607909B1
(en)
|
2020-08-19 |
2023-12-01 |
젠코어 인코포레이티드 |
Anti-CD28 composition
|
TW202227625A
(en)
|
2020-08-28 |
2022-07-16 |
美商建南德克公司 |
Crispr/cas9 multiplex knockout of host cell proteins
|
AU2021336734A1
(en)
|
2020-09-01 |
2023-03-09 |
Merck Patent Gmbh |
NKp30 binders
|
EP4208201A1
(en)
|
2020-09-04 |
2023-07-12 |
F. Hoffmann-La Roche AG |
Antibody that binds to vegf-a and ang2 and methods of use
|
KR20230082632A
(en)
|
2020-10-05 |
2023-06-08 |
제넨테크, 인크. |
Dosing for Treatment with Anti-FCRH5/Anti-CD3 Bispecific Antibodies
|
CA3198409A1
(en)
|
2020-10-07 |
2022-04-14 |
National University Corporation Chiba University |
Novel anti-glycan antibody and use thereof
|
KR20230086703A
(en)
|
2020-10-14 |
2023-06-15 |
데날리 테라퓨틱스 인크. |
Fusion protein containing sulfoglucosamine sulfohydrolase enzyme and method thereof
|
TW202233671A
(en)
|
2020-10-20 |
2022-09-01 |
美商建南德克公司 |
Peg-conjugated anti-mertk antibodies and methods of use
|
WO2022090181A1
(en)
|
2020-10-28 |
2022-05-05 |
F. Hoffmann-La Roche Ag |
Improved antigen binding receptors
|
KR20230093483A
(en)
|
2020-10-29 |
2023-06-27 |
포르미콘 아게 |
ACE2 Fusion Proteins and Uses Thereof
|
US20220162329A1
(en)
|
2020-11-04 |
2022-05-26 |
Genentech, Inc. |
Dosing for treatment with anti-cd20/anti-cd3 bispecific antibodies
|
AU2021374590A1
(en)
|
2020-11-04 |
2023-06-01 |
Genentech, Inc. |
Subcutaneous dosing of anti-cd20/anti-cd3 bispecific antibodies
|
CA3196191A1
(en)
|
2020-11-04 |
2022-05-12 |
Chi-Chung Li |
Dosing for treatment with anti-cd20/anti-cd3 bispecific antibodies and anti-cd79b antibody drug conjugates
|
JP2023549316A
(en)
|
2020-11-16 |
2023-11-24 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
Combination therapy with CD40 agonists targeting FAP
|
JP7326584B2
(en)
|
2020-12-17 |
2023-08-15 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
Anti-HLA-G antibody and use thereof
|
IL304067A
(en)
|
2021-01-06 |
2023-08-01 |
Hoffmann La Roche |
Combination therapy employing a pd1-lag3 bispecific antibody and a cd20 t cell bispecific antibody
|
WO2022148853A1
(en)
|
2021-01-11 |
2022-07-14 |
F. Hoffmann-La Roche Ag |
Immunoconjugates
|
EP4277705A1
(en)
|
2021-01-12 |
2023-11-22 |
F. Hoffmann-La Roche AG |
Split antibodies which bind to cancer cells and target radionuclides to said cells
|
EP4277668A1
(en)
|
2021-01-13 |
2023-11-22 |
F. Hoffmann-La Roche AG |
Combination therapy
|
AU2022207985A1
(en)
|
2021-01-13 |
2023-07-06 |
Visterra, Inc. |
Humanized complement 5a receptor 1 antibodies and methods of use thereof
|
GB2603166A
(en)
|
2021-01-29 |
2022-08-03 |
Thelper As |
Therapeutic and Diagnostic Agents and Uses Thereof
|
JP2024509695A
(en)
|
2021-02-03 |
2024-03-05 |
ジェネンテック, インコーポレイテッド |
Multispecific binding proteolysis platform and methods of use
|
AU2022218137A1
(en)
|
2021-02-03 |
2023-08-24 |
Mozart Therapeutics, Inc. |
Binding agents and methods of using the same
|
JP2024509543A
(en)
|
2021-03-03 |
2024-03-04 |
フォーマイコン アーゲー |
Formulation of ACE2 Fc fusion protein
|
CN112980851A
(en)
*
|
2021-03-03 |
2021-06-18 |
上海奥浦迈生物科技股份有限公司 |
Method for efficiently detecting fusion protein/antibody Fc segment incapable of mediating ADCC (ADCC-mediated cancer cell mediated cytotoxicity) and CDC (CDC) activities
|
JP2024512324A
(en)
|
2021-03-05 |
2024-03-19 |
ジーオー セラピューティクス,インコーポレイテッド |
Anti-glycoCD44 antibodies and their uses
|
CN117157319A
(en)
|
2021-03-09 |
2023-12-01 |
Xencor股份有限公司 |
Heterodimeric antibodies that bind CD3 and CLDN6
|
JP2024512382A
(en)
|
2021-03-09 |
2024-03-19 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
Combination therapy of PD-1-targeted IL-2 variant immunoconjugates and anti-TYRP1/anti-CD3 bispecific antibodies
|
JP2024508949A
(en)
|
2021-03-09 |
2024-02-28 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
Combination therapy with PD-1-targeted IL-2 mutant immunoconjugates and FAP/4-1BB binding molecules
|
KR20230154311A
(en)
|
2021-03-10 |
2023-11-07 |
젠코어 인코포레이티드 |
Heterodimeric antibodies binding to CD3 and GPC3
|
JP2024512377A
(en)
|
2021-03-12 |
2024-03-19 |
ジェネンテック, インコーポレイテッド |
Anti-KLK7 antibodies, anti-KLK5 antibodies, multispecific anti-KLK5/KLK7 antibodies, and methods of use
|
WO2022198192A1
(en)
|
2021-03-15 |
2022-09-22 |
Genentech, Inc. |
Compositions and methods of treating lupus nephritis
|
WO2022197877A1
(en)
|
2021-03-19 |
2022-09-22 |
Genentech, Inc. |
Methods and compositions for time delayed bio-orthogonal release of cytotoxic agents
|
CN117157312A
(en)
|
2021-03-30 |
2023-12-01 |
豪夫迈·罗氏有限公司 |
Protease-activated polypeptides
|
TW202304994A
(en)
|
2021-04-02 |
2023-02-01 |
美商泰尼歐生物公司 |
Agonistic anti-il-2r antibodies and methods of use
|
TW202304524A
(en)
|
2021-04-10 |
2023-02-01 |
美商普方生物製藥美國公司 |
Folr1 binding agents, conjugates thereof and methods of using the same
|
KR20230172538A
(en)
*
|
2021-04-14 |
2023-12-22 |
안자리움 바이오사이언시스 아게 |
FC-derived polypeptides
|
EP4326855A1
(en)
|
2021-04-19 |
2024-02-28 |
Genentech, Inc. |
Modified mammalian cells
|
WO2022226317A1
(en)
|
2021-04-23 |
2022-10-27 |
Profoundbio Us Co. |
Anti-cd70 antibodies, conjugates thereof and methods of using the same
|
AU2021443863A1
(en)
|
2021-04-30 |
2023-10-26 |
F. Hoffmann-La Roche Ag |
Dosing for treatment with anti-cd20/anti-cd3 bispecific antibody
|
AU2021443318A1
(en)
|
2021-04-30 |
2023-09-07 |
F. Hoffmann-La Roche Ag |
Dosing for combination treatment with anti-cd20/anti-cd3 bispecific antibody and anti-cd79b antibody drug conjugate
|
EP4335868A1
(en)
|
2021-05-07 |
2024-03-13 |
Innovent Biologics (Suzhou) Co., Ltd. |
Fc mutant with altered binding to fc receptor
|
WO2022243261A1
(en)
|
2021-05-19 |
2022-11-24 |
F. Hoffmann-La Roche Ag |
Agonistic cd40 antigen binding molecules targeting cea
|
KR20240010469A
(en)
|
2021-05-21 |
2024-01-23 |
제넨테크, 인크. |
Modified cells for production of recombinant products of interest
|
AR126009A1
(en)
|
2021-06-02 |
2023-08-30 |
Hoffmann La Roche |
CD28 ANTIGEN-BINDING AGONIST MOLECULES THAT TARGET EPCAM
|
WO2022265331A1
(en)
*
|
2021-06-14 |
2022-12-22 |
고려대학교 산학협력단 |
Fc variants with controlled immune mechanism and increased blood half-life
|
BR112023026966A2
(en)
|
2021-07-02 |
2024-03-12 |
Hoffmann La Roche |
METHODS FOR TREATING AN INDIVIDUAL WITH MELANOMA, FOR ACHIEVING A CLINICAL RESPONSE, FOR TREATING AN INDIVIDUAL WITH NON-HODGKIN LYMPHOMA, FOR TREATING A POPULATION OF INDIVIDUALS WITH NON-HODGKIN LYMPHOMA, AND FOR TREATING AN INDIVIDUAL WITH METASTATIC COLORECTAL CANCER
|
TW202320857A
(en)
|
2021-07-06 |
2023-06-01 |
美商普方生物製藥美國公司 |
Linkers, drug linkers and conjugates thereof and methods of using the same
|
WO2023288182A1
(en)
|
2021-07-12 |
2023-01-19 |
Genentech, Inc. |
Structures for reducing antibody-lipase binding
|
US20230049152A1
(en)
|
2021-07-14 |
2023-02-16 |
Genentech, Inc. |
Anti-c-c motif chemokine receptor 8 (ccr8) antibodies and methods of use
|
WO2023001884A1
(en)
|
2021-07-22 |
2023-01-26 |
F. Hoffmann-La Roche Ag |
Heterodimeric fc domain antibodies
|
CN117715936A
(en)
|
2021-07-28 |
2024-03-15 |
豪夫迈·罗氏有限公司 |
Methods and compositions for treating cancer
|
AU2022320051A1
(en)
|
2021-07-30 |
2024-01-25 |
ONA Therapeutics S.L. |
Anti-cd36 antibodies and their use to treat cancer
|
WO2023012147A1
(en)
|
2021-08-03 |
2023-02-09 |
F. Hoffmann-La Roche Ag |
Bispecific antibodies and methods of use
|
AU2022324456A1
(en)
|
2021-08-05 |
2024-02-15 |
Go Therapeutics, Inc. |
Anti-glyco-muc4 antibodies and their uses
|
CA3230934A1
(en)
|
2021-09-03 |
2023-03-09 |
Go Therapeutics, Inc. |
Anti-glyco-cmet antibodies and their uses
|
WO2023034571A1
(en)
|
2021-09-03 |
2023-03-09 |
Go Therapeutics, Inc. |
Anti-glyco-lamp1 antibodies and their uses
|
WO2023056403A1
(en)
|
2021-09-30 |
2023-04-06 |
Genentech, Inc. |
Methods for treatment of hematologic cancers using anti-tigit antibodies, anti-cd38 antibodies, and pd-1 axis binding antagonists
|
WO2023056069A1
(en)
|
2021-09-30 |
2023-04-06 |
Angiex, Inc. |
Degrader-antibody conjugates and methods of using same
|
WO2023062048A1
(en)
|
2021-10-14 |
2023-04-20 |
F. Hoffmann-La Roche Ag |
Alternative pd1-il7v immunoconjugates for the treatment of cancer
|
WO2023064876A1
(en)
|
2021-10-14 |
2023-04-20 |
Teneobio, Inc. |
Mesothelin binding proteins and uses thereof
|
WO2023062050A1
(en)
|
2021-10-14 |
2023-04-20 |
F. Hoffmann-La Roche Ag |
New interleukin-7 immunoconjugates
|
WO2023076876A1
(en)
|
2021-10-26 |
2023-05-04 |
Mozart Therapeutics, Inc. |
Modulation of immune responses to viral vectors
|
TW202342095A
(en)
|
2021-11-05 |
2023-11-01 |
英商阿斯特捷利康英國股份有限公司 |
Composition for treatment and prevention of covid-19
|
WO2023079102A2
(en)
|
2021-11-05 |
2023-05-11 |
Alligator Bioscience Ab |
Novel peptides
|
WO2023091887A1
(en)
|
2021-11-16 |
2023-05-25 |
Genentech, Inc. |
Methods and compositions for treating systemic lupus erythematosus (sle) with mosunetuzumab
|
WO2023088876A1
(en)
|
2021-11-16 |
2023-05-25 |
Apogenix Ag |
Multi-specific immune modulators
|
WO2023094507A1
(en)
|
2021-11-24 |
2023-06-01 |
Formycon Ag |
Improved ace2 fusion proteins
|
WO2023094571A1
(en)
|
2021-11-25 |
2023-06-01 |
Formycon Ag |
Stabilization of ace2 fusion proteins
|
WO2023094413A1
(en)
|
2021-11-25 |
2023-06-01 |
F. Hoffmann-La Roche Ag |
Improved antigen binding receptors
|
WO2023094569A1
(en)
|
2021-11-26 |
2023-06-01 |
F. Hoffmann-La Roche Ag |
Combination therapy of anti-tyrp1/anti-cd3 bispecific antibodies and tyrp1-specific antibodies
|
AR127887A1
(en)
|
2021-12-10 |
2024-03-06 |
Hoffmann La Roche |
ANTIBODIES THAT BIND CD3 AND PLAP
|
TW202330582A
(en)
|
2021-12-15 |
2023-08-01 |
美商建南德克公司 |
Stabilized il-18 polypeptides and uses thereof
|
WO2023114951A1
(en)
|
2021-12-17 |
2023-06-22 |
Viiv Healthcare Company |
Combination therapies for hiv infections and uses thereof
|
TW202340248A
(en)
|
2021-12-20 |
2023-10-16 |
瑞士商赫孚孟拉羅股份公司 |
Agonistic ltbr antibodies and bispecific antibodies comprising them
|
TW202340251A
(en)
|
2022-01-19 |
2023-10-16 |
美商建南德克公司 |
Anti-notch2 antibodies and conjugates and methods of use
|
GB202201137D0
(en)
|
2022-01-28 |
2022-03-16 |
Thelper As |
Therapeutic and diagnostic agents and uses thereof
|
US20230303719A1
(en)
|
2022-03-03 |
2023-09-28 |
Yale University |
Humanized 3e10 antibodies, variants, and antigen binding fragments thereof
|
US20230414750A1
(en)
|
2022-03-23 |
2023-12-28 |
Hoffmann-La Roche Inc. |
Combination treatment of an anti-cd20/anti-cd3 bispecific antibody and chemotherapy
|
WO2023180511A1
(en)
|
2022-03-25 |
2023-09-28 |
F. Hoffmann-La Roche Ag |
Improved chimeric receptors
|
WO2023186756A1
(en)
|
2022-03-28 |
2023-10-05 |
F. Hoffmann-La Roche Ag |
Interferon gamma variants and antigen binding molecules comprising these
|
WO2023186760A1
(en)
|
2022-03-28 |
2023-10-05 |
F. Hoffmann-La Roche Ag |
Improved folr1 protease-activatable t cell bispecific antibodies
|
WO2023191816A1
(en)
|
2022-04-01 |
2023-10-05 |
Genentech, Inc. |
Dosing for treatment with anti-fcrh5/anti-cd3 bispecific antibodies
|
WO2023201299A1
(en)
|
2022-04-13 |
2023-10-19 |
Genentech, Inc. |
Pharmaceutical compositions of therapeutic proteins and methods of use
|
WO2023198727A1
(en)
|
2022-04-13 |
2023-10-19 |
F. Hoffmann-La Roche Ag |
Pharmaceutical compositions of anti-cd20/anti-cd3 bispecific antibodies and methods of use
|
WO2023209177A1
(en)
|
2022-04-29 |
2023-11-02 |
Astrazeneca Uk Limited |
Sars-cov-2 antibodies and methods of using the same
|
WO2023212304A1
(en)
|
2022-04-29 |
2023-11-02 |
23Andme, Inc. |
Antigen binding proteins
|
WO2023219613A1
(en)
|
2022-05-11 |
2023-11-16 |
Genentech, Inc. |
Dosing for treatment with anti-fcrh5/anti-cd3 bispecific antibodies
|
TW202402810A
(en)
|
2022-05-11 |
2024-01-16 |
瑞士商赫孚孟拉羅股份公司 |
Antibody that binds to vegf-a and il6 and methods of use
|
WO2023240058A2
(en)
|
2022-06-07 |
2023-12-14 |
Genentech, Inc. |
Prognostic and therapeutic methods for cancer
|
WO2023239803A1
(en)
|
2022-06-08 |
2023-12-14 |
Angiex, Inc. |
Anti-tm4sf1 antibody-drug conjugates comprising cleavable linkers and methods of using same
|
WO2024015897A1
(en)
|
2022-07-13 |
2024-01-18 |
Genentech, Inc. |
Dosing for treatment with anti-fcrh5/anti-cd3 bispecific antibodies
|
WO2024020432A1
(en)
|
2022-07-19 |
2024-01-25 |
Genentech, Inc. |
Dosing for treatment with anti-fcrh5/anti-cd3 bispecific antibodies
|
WO2024020164A2
(en)
|
2022-07-21 |
2024-01-25 |
Firefly Bio, Inc. |
Glucocorticoid receptor agonists and conjugates thereof
|
WO2024020564A1
(en)
|
2022-07-22 |
2024-01-25 |
Genentech, Inc. |
Anti-steap1 antigen-binding molecules and uses thereof
|
WO2024023271A1
(en)
|
2022-07-27 |
2024-02-01 |
Ablynx Nv |
Polypeptides binding to a specific epitope of the neonatal fc receptor
|
WO2024026358A1
(en)
|
2022-07-27 |
2024-02-01 |
Teneobio, Inc. |
Mesothelin binding proteins and uses thereof
|
US20240042021A1
(en)
|
2022-08-01 |
2024-02-08 |
Flagship Pioneering Innovations Vii, Llc |
Immunomodulatory proteins and related methods
|
WO2024030956A2
(en)
|
2022-08-03 |
2024-02-08 |
Mozart Therapeutics, Inc. |
Cd39-specific binding agents and methods of using the same
|
WO2024068572A1
(en)
|
2022-09-28 |
2024-04-04 |
F. Hoffmann-La Roche Ag |
Improved protease-activatable t cell bispecific antibodies
|
WO2024068705A1
(en)
|
2022-09-29 |
2024-04-04 |
F. Hoffmann-La Roche Ag |
Protease-activated polypeptides
|