SG10201501804WA - Methods and genotyping panels for detecting alleles, genomes, and transcriptomes - Google Patents

Methods and genotyping panels for detecting alleles, genomes, and transcriptomes

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Publication number
SG10201501804WA
SG10201501804WA SG10201501804WA SG10201501804WA SG10201501804WA SG 10201501804W A SG10201501804W A SG 10201501804WA SG 10201501804W A SG10201501804W A SG 10201501804WA SG 10201501804W A SG10201501804W A SG 10201501804WA SG 10201501804W A SG10201501804W A SG 10201501804WA
Authority
SG
Singapore
Prior art keywords
transcriptomes
genomes
methods
detecting alleles
genotyping
Prior art date
Application number
SG10201501804WA
Other languages
English (en)
Inventor
Arnold R Oliphant
Kurt A Krummel
Haichuan Zhang
Andrew S Katz
Original Assignee
Celula Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celula Inc filed Critical Celula Inc
Publication of SG10201501804WA publication Critical patent/SG10201501804WA/en

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6881Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/16Primer sets for multiplex assays

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
SG10201501804WA 2008-12-22 2009-12-22 Methods and genotyping panels for detecting alleles, genomes, and transcriptomes SG10201501804WA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US14006308P 2008-12-22 2008-12-22
US16618809P 2009-04-02 2009-04-02
US23123209P 2009-08-04 2009-08-04

Publications (1)

Publication Number Publication Date
SG10201501804WA true SG10201501804WA (en) 2015-05-28

Family

ID=41785800

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10201501804WA SG10201501804WA (en) 2008-12-22 2009-12-22 Methods and genotyping panels for detecting alleles, genomes, and transcriptomes
SG2011046125A SG172345A1 (en) 2008-12-22 2009-12-22 Methods and genotyping panels for detecting alleles, genomes, and transcriptomes

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG2011046125A SG172345A1 (en) 2008-12-22 2009-12-22 Methods and genotyping panels for detecting alleles, genomes, and transcriptomes

Country Status (10)

Country Link
US (2) US9051602B2 (ja)
EP (1) EP2379746B1 (ja)
JP (1) JP2012513217A (ja)
KR (1) KR101781147B1 (ja)
CN (2) CN102325901A (ja)
AU (2) AU2009329946B2 (ja)
CA (1) CA2748030A1 (ja)
MY (1) MY161966A (ja)
SG (2) SG10201501804WA (ja)
WO (1) WO2010075459A1 (ja)

Families Citing this family (85)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11111544B2 (en) 2005-07-29 2021-09-07 Natera, Inc. System and method for cleaning noisy genetic data and determining chromosome copy number
US11111543B2 (en) 2005-07-29 2021-09-07 Natera, Inc. System and method for cleaning noisy genetic data and determining chromosome copy number
US9424392B2 (en) 2005-11-26 2016-08-23 Natera, Inc. System and method for cleaning noisy genetic data from target individuals using genetic data from genetically related individuals
US10081839B2 (en) 2005-07-29 2018-09-25 Natera, Inc System and method for cleaning noisy genetic data and determining chromosome copy number
US10083273B2 (en) 2005-07-29 2018-09-25 Natera, Inc. System and method for cleaning noisy genetic data and determining chromosome copy number
CA3116156C (en) 2008-08-04 2023-08-08 Natera, Inc. Methods for allele calling and ploidy calling
US9134221B2 (en) 2009-03-10 2015-09-15 The Regents Of The University Of California Fluidic flow cytometry devices and particle sensing based on signal-encoding
US9645010B2 (en) 2009-03-10 2017-05-09 The Regents Of The University Of California Fluidic flow cytometry devices and methods
WO2011041485A1 (en) 2009-09-30 2011-04-07 Gene Security Network, Inc. Methods for non-invasive prenatal ploidy calling
CN102770558B (zh) 2009-11-05 2016-04-06 香港中文大学 由母本生物样品进行胎儿基因组的分析
EP2854057B1 (en) 2010-05-18 2018-03-07 Natera, Inc. Methods for non-invasive pre-natal ploidy calling
US20190010543A1 (en) 2010-05-18 2019-01-10 Natera, Inc. Methods for simultaneous amplification of target loci
US11939634B2 (en) 2010-05-18 2024-03-26 Natera, Inc. Methods for simultaneous amplification of target loci
US10316362B2 (en) 2010-05-18 2019-06-11 Natera, Inc. Methods for simultaneous amplification of target loci
US11408031B2 (en) 2010-05-18 2022-08-09 Natera, Inc. Methods for non-invasive prenatal paternity testing
US9677118B2 (en) 2014-04-21 2017-06-13 Natera, Inc. Methods for simultaneous amplification of target loci
US11332793B2 (en) 2010-05-18 2022-05-17 Natera, Inc. Methods for simultaneous amplification of target loci
US11322224B2 (en) 2010-05-18 2022-05-03 Natera, Inc. Methods for non-invasive prenatal ploidy calling
US11326208B2 (en) 2010-05-18 2022-05-10 Natera, Inc. Methods for nested PCR amplification of cell-free DNA
US11339429B2 (en) 2010-05-18 2022-05-24 Natera, Inc. Methods for non-invasive prenatal ploidy calling
US11332785B2 (en) 2010-05-18 2022-05-17 Natera, Inc. Methods for non-invasive prenatal ploidy calling
US20120077191A1 (en) 2010-08-11 2012-03-29 Celula, Inc. Genotyping dna
WO2012027483A2 (en) * 2010-08-24 2012-03-01 Bio Dx, Inc. Defining diagnostic and therapeutic targets of conserved free floating fetal dna in maternal circulating blood
US10024819B2 (en) 2010-10-21 2018-07-17 The Regents Of The University Of California Microfluidics with wirelessly powered electronic circuits
SG10202008532PA (en) * 2010-11-30 2020-10-29 Univ Hong Kong Chinese Detection of genetic or molecular aberrations associated with cancer
RU2620959C2 (ru) 2010-12-22 2017-05-30 Натера, Инк. Способы неинвазивного пренатального установления отцовства
WO2012108920A1 (en) 2011-02-09 2012-08-16 Natera, Inc Methods for non-invasive prenatal ploidy calling
JP5837622B2 (ja) * 2011-02-24 2015-12-24 ザ チャイニーズ ユニバーシティー オブ ホンコンThe Chinese University Of Hongkong 多胎妊娠の分子検査
EP2705166A4 (en) * 2011-05-06 2014-12-17 Celula Inc METHOD AND COMPOSITIONS FOR COMPLETE ISOTHERMIC GENOMAMPLIFICATION
US20140235474A1 (en) 2011-06-24 2014-08-21 Sequenom, Inc. Methods and processes for non invasive assessment of a genetic variation
WO2013010134A2 (en) 2011-07-14 2013-01-17 Celula, Inc. Systems, apparatus and methods for biochemical analysis
US9984198B2 (en) 2011-10-06 2018-05-29 Sequenom, Inc. Reducing sequence read count error in assessment of complex genetic variations
US10424394B2 (en) 2011-10-06 2019-09-24 Sequenom, Inc. Methods and processes for non-invasive assessment of genetic variations
CA2850785C (en) 2011-10-06 2022-12-13 Sequenom, Inc. Methods and processes for non-invasive assessment of genetic variations
US9367663B2 (en) 2011-10-06 2016-06-14 Sequenom, Inc. Methods and processes for non-invasive assessment of genetic variations
US10196681B2 (en) 2011-10-06 2019-02-05 Sequenom, Inc. Methods and processes for non-invasive assessment of genetic variations
US8688388B2 (en) 2011-10-11 2014-04-01 Sequenom, Inc. Methods and processes for non-invasive assessment of genetic variations
RU2599419C2 (ru) * 2011-12-17 2016-10-10 БиДжиАй ДАЙЭГНОСИС КО., ЛТД. Способы и системы для определения того, является ли геном аномальным
US20140370504A1 (en) * 2011-12-31 2014-12-18 Bgi Diagnosis Co., Ltd. Method for detecting genetic variation
WO2013109981A1 (en) 2012-01-20 2013-07-25 Sequenom, Inc. Diagnostic processes that factor experimental conditions
US9920361B2 (en) 2012-05-21 2018-03-20 Sequenom, Inc. Methods and compositions for analyzing nucleic acid
US10504613B2 (en) 2012-12-20 2019-12-10 Sequenom, Inc. Methods and processes for non-invasive assessment of genetic variations
EP2860261B1 (en) * 2012-05-23 2018-09-12 BGI Genomics Co., Ltd. Method and system for identifying types of twins
WO2013192342A1 (en) * 2012-06-20 2013-12-27 Celula, Inc. Materials and methods for processing cell populations
US10497461B2 (en) 2012-06-22 2019-12-03 Sequenom, Inc. Methods and processes for non-invasive assessment of genetic variations
US20140065621A1 (en) * 2012-09-04 2014-03-06 Natera, Inc. Methods for increasing fetal fraction in maternal blood
US10482994B2 (en) 2012-10-04 2019-11-19 Sequenom, Inc. Methods and processes for non-invasive assessment of genetic variations
JP6396911B2 (ja) 2012-10-15 2018-09-26 ナノセレクト バイオメディカル, インコーポレイテッド 粒子を選別するためのシステム、装置、および、方法
CN105190656B (zh) 2013-01-17 2018-01-16 佩索纳里斯公司 用于遗传分析的方法和***
US20130309666A1 (en) 2013-01-25 2013-11-21 Sequenom, Inc. Methods and processes for non-invasive assessment of genetic variations
AU2014231358A1 (en) * 2013-03-15 2015-09-24 The Chinese University Of Hong Kong Determining fetal genomes for multiple fetus pregnancies
HUE061261T2 (hu) 2013-04-03 2023-05-28 Sequenom Inc Eljárások és folyamatok genetikai variánsok nem invazív értékelésére
EP3004383B1 (en) 2013-05-24 2019-04-24 Sequenom, Inc. Methods for non-invasive assessment of genetic variations using area-under-curve (auc) analysis
BR112015032031B1 (pt) 2013-06-21 2023-05-16 Sequenom, Inc Métodos e processos para avaliação não invasiva das variações genéticas
GB201318369D0 (en) * 2013-10-17 2013-12-04 Univ Leuven Kath Methods using BAF
EP3039161B1 (en) 2013-08-30 2021-10-06 Personalis, Inc. Methods and systems for genomic analysis
WO2015048535A1 (en) 2013-09-27 2015-04-02 Natera, Inc. Prenatal diagnostic resting standards
US10577655B2 (en) 2013-09-27 2020-03-03 Natera, Inc. Cell free DNA diagnostic testing standards
US10262755B2 (en) 2014-04-21 2019-04-16 Natera, Inc. Detecting cancer mutations and aneuploidy in chromosomal segments
AU2014329493B2 (en) 2013-10-04 2020-09-03 Sequenom, Inc. Methods and processes for non-invasive assessment of genetic variations
EP3495496B1 (en) 2013-10-07 2020-11-25 Sequenom, Inc. Methods and processes for non-invasive assessment of chromosome alterations
CN109971852A (zh) 2014-04-21 2019-07-05 纳特拉公司 检测染色体片段中的突变和倍性
WO2016010401A1 (ko) * 2014-07-18 2016-01-21 에스케이텔레콘 주식회사 산모의 혈청 dna를 이용한 태아의 단일유전자 유전변이의 예측방법
US20160034640A1 (en) 2014-07-30 2016-02-04 Sequenom, Inc. Methods and processes for non-invasive assessment of genetic variations
EP4026913A1 (en) 2014-10-30 2022-07-13 Personalis, Inc. Methods for using mosaicism in nucleic acids sampled distal to their origin
CN107109324B (zh) * 2015-01-16 2019-11-08 深圳华大基因股份有限公司 确定胎儿核酸含量的方法和装置
WO2016183106A1 (en) 2015-05-11 2016-11-17 Natera, Inc. Methods and compositions for determining ploidy
JP2018518162A (ja) * 2015-05-12 2018-07-12 ジェン−プローブ・インコーポレーテッド 血液サンプルをプールする方法
US11299783B2 (en) 2016-05-27 2022-04-12 Personalis, Inc. Methods and systems for genetic analysis
EP3491560A1 (en) 2016-07-27 2019-06-05 Sequenom, Inc. Genetic copy number alteration classifications
WO2018067517A1 (en) 2016-10-04 2018-04-12 Natera, Inc. Methods for characterizing copy number variation using proximity-litigation sequencing
US10011870B2 (en) 2016-12-07 2018-07-03 Natera, Inc. Compositions and methods for identifying nucleic acid molecules
CN106480221B (zh) * 2016-12-19 2019-07-23 北京林业大学 基于基因拷贝数变异位点对林木群体基因型分型的方法
CN106874712B (zh) * 2017-01-13 2019-01-29 天津大学 一种基于池化时间序列特征表示的细胞***事件识别方法
CA3207879A1 (en) 2017-01-24 2018-08-02 Sequenom, Inc. Methods and processes for assessment of genetic variations
US10894976B2 (en) 2017-02-21 2021-01-19 Natera, Inc. Compositions, methods, and kits for isolating nucleic acids
KR102031841B1 (ko) * 2017-12-22 2019-10-15 테라젠지놈케어 주식회사 모체 시료 중 태아 분획을 결정하는 방법
EP3527659A1 (en) * 2018-02-14 2019-08-21 Universidad del Pais Vasco Method for obtaining a spermatozoid cell population with improved fitness
JP2021520816A (ja) 2018-04-14 2021-08-26 ナテラ, インコーポレイテッド 循環腫瘍dnaの個別化された検出を用いる癌検出およびモニタリングの方法
US11525159B2 (en) 2018-07-03 2022-12-13 Natera, Inc. Methods for detection of donor-derived cell-free DNA
US20220056534A1 (en) * 2018-12-17 2022-02-24 Natera, Inc. Methods for analysis of circulating cells
EP4058185A4 (en) * 2019-11-14 2023-11-29 Bio-Rad Laboratories, Inc. PARTITION-BASED DETERMINATION OF A TARGET COPY NUMBER FOR INDIVIDUAL CELLS BY AMPLIFICATION WITHOUT ENDPOINT
WO2021222434A1 (en) * 2020-04-29 2021-11-04 Personalis, Inc. Composite biomarkers for immunotherapy for cancer
CN111534605A (zh) * 2020-06-05 2020-08-14 复旦大学附属妇产科医院 一种基于snp基因型的单卵双胞胎、异卵双胞胎和第二极体参与受精双胞胎的鉴定方法
CN116855617A (zh) * 2023-08-31 2023-10-10 安诺优达基因科技(北京)有限公司 基于核心家系的串联重复变异分型检测方法及其应用

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7226798B2 (en) 1999-07-19 2007-06-05 United Microelectronics Corp. Fabrication method for a multi-layered thin film protective layer
US7045319B2 (en) 2001-10-30 2006-05-16 Ribomed Biotechnologies, Inc. Molecular detection systems utilizing reiterative oligonucleotide synthesis
US20070178478A1 (en) * 2002-05-08 2007-08-02 Dhallan Ravinder S Methods for detection of genetic disorders
WO2005001122A2 (en) 2003-06-27 2005-01-06 Adnavance Technologies, Inc. Electrochemical detection of dna binding
WO2005022147A1 (en) * 2003-08-28 2005-03-10 Celula, Inc. Methods and apparatus for sorting cells using an optical switch in a microfluidic channel network
AU2004270220B2 (en) 2003-09-05 2009-03-05 The Chinese University Of Hong Kong Method for non-invasive prenatal diagnosis
ATE458044T1 (de) * 2003-12-10 2010-03-15 Takara Bio Inc Verfahren zur nukleinsäureamplifikation
US20070122823A1 (en) 2005-09-01 2007-05-31 Bianchi Diana W Amniotic fluid cell-free fetal DNA fragment size pattern for prenatal diagnosis
DE102005059227A1 (de) * 2005-12-12 2007-06-14 Advalytix Ag Verfahren zur Bestimmung des Genotyps aus einer biologischen Probe enthaltend Nukleinsäuren unterschiedlicher Individuen
EP2423334A3 (en) * 2006-02-02 2012-04-18 The Board of Trustees of The Leland Stanford Junior University Non-invasive fetal genetic screening by digital analysis
CN101421410A (zh) 2006-03-06 2009-04-29 纽约市哥伦比亚大学托管会 从混合的胎儿-母体来源中特异性扩增胎儿dna序列
WO2007147018A1 (en) 2006-06-14 2007-12-21 Cellpoint Diagnostics, Inc. Analysis of rare cell-enriched samples
WO2007147079A2 (en) 2006-06-14 2007-12-21 Living Microsystems, Inc. Rare cell analysis using sample splitting and dna tags
EP2589668A1 (en) * 2006-06-14 2013-05-08 Verinata Health, Inc Rare cell analysis using sample splitting and DNA tags
WO2008048931A1 (en) 2006-10-16 2008-04-24 Celula Inc. Methods and compositions for differential expansion of fetal cells in maternal blood and their use
US8173370B2 (en) * 2007-02-08 2012-05-08 Sequenom, Inc. Nucleic acid-based tests for RHD typing, gender determination and nucleic acid quantification
ITTO20070307A1 (it) * 2007-05-04 2008-11-05 Silicon Biosystems Spa Metodo e dispositivo per la diagnosi prenatale non-invasiva
US20110033862A1 (en) * 2008-02-19 2011-02-10 Gene Security Network, Inc. Methods for cell genotyping
DE102008019132A1 (de) * 2008-04-16 2009-10-22 Olympus Life Science Research Europa Gmbh Verfahren zur quantitativen Bestimmung der Kopienzahl einer vorbestimmten Sequenz in einer Probe

Also Published As

Publication number Publication date
CA2748030A1 (en) 2010-07-01
US9051602B2 (en) 2015-06-09
CN104531837A (zh) 2015-04-22
MY161966A (en) 2017-05-15
KR101781147B1 (ko) 2017-10-10
AU2016202178A1 (en) 2016-04-28
CN102325901A (zh) 2012-01-18
SG172345A1 (en) 2011-07-28
EP2379746B1 (en) 2017-03-08
AU2009329946A1 (en) 2011-08-11
US20110086769A1 (en) 2011-04-14
KR20110137286A (ko) 2011-12-22
AU2009329946B2 (en) 2016-01-07
JP2012513217A (ja) 2012-06-14
US20150232937A1 (en) 2015-08-20
EP2379746A1 (en) 2011-10-26
US9994902B2 (en) 2018-06-12
WO2010075459A1 (en) 2010-07-01

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