SE9002596D0 - A method for synthesis of prostaglandin derivatives - Google Patents

A method for synthesis of prostaglandin derivatives

Info

Publication number: SE9002596D0
Authority: SE; Sweden
Prior art keywords: alkyl; synthesis; hydroxyl; halogen; hydrogen
Prior art date: 1990-08-08

Application number

SE9002596A

Other languages

English (en)

Inventor

Bahram Resul

Original Assignee

Pharmacia Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-08-08

Filing date

1990-08-08

Publication date

1990-08-08

1990-08-08 Application filed by Pharmacia Ab filed Critical Pharmacia Ab

1990-08-08 Priority to SE9002596A priority Critical patent/SE9002596D0/sv

1990-08-08 Publication of SE9002596D0 publication Critical patent/SE9002596D0/sv

1991-08-08 Priority to SU915011925A priority patent/RU2073668C1/ru

1991-08-08 Priority to EP91914853A priority patent/EP0495069B1/en

1991-08-08 Priority to RO92-200479A priority patent/RO109332B1/ro

1991-08-08 Priority to DE69116541T priority patent/DE69116541T2/de

1991-08-08 Priority to CA002067341A priority patent/CA2067341C/en

1991-08-08 Priority to AU83915/91A priority patent/AU645129C/en

1991-08-08 Priority to JP3513618A priority patent/JP2670521B2/ja

1991-08-08 Priority to AT91914853T priority patent/ATE133162T1/de

1991-08-08 Priority to PCT/SE1991/000525 priority patent/WO1992002496A1/en

1991-08-08 Priority to HU921194A priority patent/HUT62874A/hu

1992-04-07 Priority to BG96194A priority patent/BG61143B1/bg

1994-02-08 Priority to US08/193,525 priority patent/US5359095A/en

Links

238000000034 method Methods 0.000 title abstract 2
230000015572 biosynthetic process Effects 0.000 title 1
150000003180 prostaglandins Chemical class 0.000 title 1
238000003786 synthesis reaction Methods 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 3
XXROGKLTLUQVRX-UHFFFAOYSA-N allyl alcohol Chemical compound OCC=C XXROGKLTLUQVRX-UHFFFAOYSA-N 0.000 abstract 2
125000003118 aryl group Chemical group 0.000 abstract 2
125000004432 carbon atom Chemical group C* 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
229910052736 halogen Inorganic materials 0.000 abstract 2
150000002367 halogens Chemical class 0.000 abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
XFXPMWWXUTWYJX-UHFFFAOYSA-N Cyanide Chemical compound N#[C-] XFXPMWWXUTWYJX-UHFFFAOYSA-N 0.000 abstract 1
238000006392 deoxygenation reaction Methods 0.000 abstract 1
XEYBRNLFEZDVAW-ARSRFYASSA-N dinoprostone Chemical compound CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(O)=O XEYBRNLFEZDVAW-ARSRFYASSA-N 0.000 abstract 1
229960002986 dinoprostone Drugs 0.000 abstract 1
125000002768 hydroxyalkyl group Chemical group 0.000 abstract 1
XEYBRNLFEZDVAW-UHFFFAOYSA-N prostaglandin E2 Natural products CCCCCC(O)C=CC1C(O)CC(=O)C1CC=CCCCC(O)=O XEYBRNLFEZDVAW-UHFFFAOYSA-N 0.000 abstract 1
125000006239 protecting group Chemical group 0.000 abstract 1
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
- C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

SE9002596A 1990-08-08 1990-08-08 A method for synthesis of prostaglandin derivatives SE9002596D0 (sv)

Priority Applications (13)

Application Number	Priority Date	Filing Date	Title
SE9002596A SE9002596D0 (sv)	1990-08-08	1990-08-08	A method for synthesis of prostaglandin derivatives
HU921194A HUT62874A (en)	1990-08-08	1991-08-08	Process for the synthesis of prostaglandin derivatives
DE69116541T DE69116541T2 (de)	1990-08-08	1991-08-08	Eine synthesemethode für prostaglandinderivate
EP91914853A EP0495069B1 (en)	1990-08-08	1991-08-08	A method for synthesis of prostaglandin derivatives
RO92-200479A RO109332B1 (ro)	1990-08-08	1991-08-08	Procedeu pentru prepararea unor analogi ai 13,14-dihidroderivatilor de prostaglandina
SU915011925A RU2073668C1 (ru)	1990-08-08	1991-08-08	СПОСОБ ПОЛУЧЕНИЯ 13,14-ДИГИДРО-17-ФЕНИЛЬНОГО АНАЛОГА PGF2α ИЛИ ПГЕ*002
CA002067341A CA2067341C (en)	1990-08-08	1991-08-08	Method for synthesis of prostaglandin derivatives
AU83915/91A AU645129C (en)	1990-08-08	1991-08-08	A method for synthesis of prostaglandin derivatives
JP3513618A JP2670521B2 (ja)	1990-08-08	1991-08-08	プロスタグランジン誘導体の合成方法
AT91914853T ATE133162T1 (de)	1990-08-08	1991-08-08	Eine synthesemethode für prostaglandinderivate
PCT/SE1991/000525 WO1992002496A1 (en)	1990-08-08	1991-08-08	A method for synthesis of prostaglandin derivatives
BG96194A BG61143B1 (bg)	1990-08-08	1992-04-07	Метод за получаване на простагландинови производни
US08/193,525 US5359095A (en)	1990-08-08	1994-02-08	Method for synthesis of prostaglandin derivatives

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
SE9002596A SE9002596D0 (sv)	1990-08-08	1990-08-08	A method for synthesis of prostaglandin derivatives

Publications (1)

Publication Number	Publication Date
SE9002596D0 true SE9002596D0 (sv)	1990-08-08

Family

ID=20380110

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SE9002596A SE9002596D0 (sv)	1990-08-08	1990-08-08	A method for synthesis of prostaglandin derivatives

Country Status (11)

Country	Link
EP (1)	EP0495069B1 (sv)
JP (1)	JP2670521B2 (sv)
AT (1)	ATE133162T1 (sv)
BG (1)	BG61143B1 (sv)
CA (1)	CA2067341C (sv)
DE (1)	DE69116541T2 (sv)
HU (1)	HUT62874A (sv)
RO (1)	RO109332B1 (sv)
RU (1)	RU2073668C1 (sv)
SE (1)	SE9002596D0 (sv)
WO (1)	WO1992002496A1 (sv)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5223537A (en) *	1991-07-23	1993-06-29	Kabi Pharmacia Ab	Method and composition for treatment of gastric and duodenal disorders
US5516796A (en) *	1994-03-24	1996-05-14	Kabi Pharmacia Ab	Thioprostaglandins and -prostaglandin-like compounds and therapeutic uses thereof
AU7672096A (en) *	1995-06-07	1998-06-03	Alcon Laboratories, Inc.	Conformationally rigid aryl- or heteroaryl prostaglandins for use in glaucoma therapy
GB0112699D0 (en)	2001-05-24	2001-07-18	Resolution Chemicals Ltd	Process for the preparation of prostglandins and analogues thereof
GB0126076D0 (en) *	2001-10-31	2001-12-19	Cascade Biochem Ltd	Improvements relating to prostaglandins and their analogues
JP2008037782A (ja) *	2006-08-04	2008-02-21	Daiichi Fine Chemical Co Ltd	プロスタグランジン誘導体の製造方法
US7642370B2 (en)	2006-08-07	2010-01-05	Daiichi Fine Chemical Co., Ltd.	Method for preparing prostaglandin derivative
US20110293549A1 (en)	2009-02-03	2011-12-01	Athena Cosmetics, Inc.	Composition, method and kit for enhancing hair
AU2009354014B2 (en) *	2009-10-16	2014-08-28	Cayman Chemical Company, Incorporated	Process for the preparation of F-series prostaglandins
KR102277188B1 (ko) *	2011-06-02	2021-07-15	키노인 제트알티.	프로스타글란딘 아미드의 신규한 제조 방법

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES416865A1 (es) *	1972-07-13	1976-03-01	Pfizer	Procedimiento para preparar w-pentanorprostaglandinas sus- tituidas en la posicion 15.
US3962312A (en) *	1972-09-21	1976-06-08	Ono Pharmaceutical Company	9,11,15-Trihydroxy prost-5-enoic acid analogues

1990
- 1990-08-08 SE SE9002596A patent/SE9002596D0/sv unknown
1991
- 1991-08-08 WO PCT/SE1991/000525 patent/WO1992002496A1/en active IP Right Grant
- 1991-08-08 AT AT91914853T patent/ATE133162T1/de not_active IP Right Cessation
- 1991-08-08 HU HU921194A patent/HUT62874A/hu unknown
- 1991-08-08 RO RO92-200479A patent/RO109332B1/ro unknown
- 1991-08-08 CA CA002067341A patent/CA2067341C/en not_active Expired - Fee Related
- 1991-08-08 DE DE69116541T patent/DE69116541T2/de not_active Expired - Fee Related
- 1991-08-08 RU SU915011925A patent/RU2073668C1/ru not_active IP Right Cessation
- 1991-08-08 JP JP3513618A patent/JP2670521B2/ja not_active Expired - Fee Related
- 1991-08-08 EP EP91914853A patent/EP0495069B1/en not_active Expired - Lifetime
1992
- 1992-04-07 BG BG96194A patent/BG61143B1/bg unknown

Also Published As

Publication number	Publication date
HUT62874A (en)	1993-06-28
EP0495069B1 (en)	1996-01-17
WO1992002496A1 (en)	1992-02-20
ATE133162T1 (de)	1996-02-15
JPH05502043A (ja)	1993-04-15
EP0495069A1 (en)	1992-07-22
BG96194A (bg)	1993-12-24
AU645129B2 (en)	1994-01-06
AU8391591A (en)	1992-03-02
RO109332B1 (ro)	1995-01-30
CA2067341C (en)	1997-09-30
RU2073668C1 (ru)	1997-02-20
JP2670521B2 (ja)	1997-10-29
BG61143B1 (bg)	1996-12-31
DE69116541D1 (en)	1996-02-29
DE69116541T2 (de)	1996-09-19
CA2067341A1 (en)	1992-02-09

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