SE8301928D0 - NEW CARBAPEN MEMBER DERIVATIVES AND PROCEDURES FOR PREPARING THEREOF - Google Patents
NEW CARBAPEN MEMBER DERIVATIVES AND PROCEDURES FOR PREPARING THEREOFInfo
- Publication number
- SE8301928D0 SE8301928D0 SE8301928A SE8301928A SE8301928D0 SE 8301928 D0 SE8301928 D0 SE 8301928D0 SE 8301928 A SE8301928 A SE 8301928A SE 8301928 A SE8301928 A SE 8301928A SE 8301928 D0 SE8301928 D0 SE 8301928D0
- Authority
- SE
- Sweden
- Prior art keywords
- derivatives
- aliphatic
- carbapen
- procedures
- preparing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
- C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
- C07D477/20—Sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Disclosed are novel carbapenem derivatives characterized by a 2- substitutent of the formula <IMAGE> wherein A represents C2-C6 straight or branched chain alkylene group and R<10> and R<11> each independently represents optionally substituted aliphatic, cycloaliphatic, cycloaliphatic- aliphatic, aryl, heterocyclyl, heterocyclyl-aliphatic, heteroaryl or heteroaraliphatic, or R<10> and R<11> taken together with the S<(+)> to which they are attached represent an optionally substituted sulfur-containing heterocyclic ring. Such derivatives are useful as potent antibacterial agents. Also disclosed are processes for the preparation of such derivatives.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US36662782A | 1982-04-08 | 1982-04-08 |
Publications (3)
Publication Number | Publication Date |
---|---|
SE8301928D0 true SE8301928D0 (en) | 1983-04-07 |
SE8301928L SE8301928L (en) | 1983-12-02 |
SE460197B SE460197B (en) | 1989-09-18 |
Family
ID=23443823
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE8301928A SE460197B (en) | 1982-04-08 | 1983-04-07 | NEW CARBAPENE MEMBER DERIVATIVES AND PROCEDURES FOR PREPARING THEREOF |
Country Status (25)
Country | Link |
---|---|
JP (1) | JPS58188887A (en) |
KR (1) | KR880001055B1 (en) |
AT (1) | AT383126B (en) |
AU (1) | AU567092B2 (en) |
BE (1) | BE896407A (en) |
CA (1) | CA1198440A (en) |
CH (1) | CH661927A5 (en) |
DE (1) | DE3312517A1 (en) |
DK (1) | DK155983A (en) |
ES (1) | ES521224A0 (en) |
FI (1) | FI74009C (en) |
FR (1) | FR2524888B1 (en) |
GB (1) | GB2118183B (en) |
GR (1) | GR78822B (en) |
HU (1) | HU190716B (en) |
IE (1) | IE55225B1 (en) |
IL (1) | IL68295A0 (en) |
IT (1) | IT1168854B (en) |
LU (1) | LU84739A1 (en) |
MY (1) | MY8700945A (en) |
NL (1) | NL8301193A (en) |
OA (1) | OA07395A (en) |
PT (1) | PT76518B (en) |
SE (1) | SE460197B (en) |
ZA (1) | ZA832411B (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4683301A (en) * | 1982-04-08 | 1987-07-28 | Bristol-Myers Company | Carbapenem antibiotics |
US4552696A (en) * | 1982-04-09 | 1985-11-12 | Bristol-Myers Company | Carbapenem antibiotics |
US4536335A (en) * | 1982-06-18 | 1985-08-20 | Bristol-Myers Company | Carbapenem antibiotics |
AT396473B (en) * | 1984-10-02 | 1993-09-27 | Bristol Myers Squibb Co | Process for the preparation of novel carbapenem derivatives |
US4665169A (en) * | 1985-09-11 | 1987-05-12 | Bristol-Myers Company | Carbapenem antibiotics |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU531084B2 (en) * | 1977-10-19 | 1983-08-11 | Merck & Co., Inc. | Azetidine derivatives |
DK165280A (en) * | 1979-04-19 | 1980-10-20 | Merck & Co Inc | PROCEDURE FOR PREPARING 2- AND 6-SUBSTITUTED 1-CARBADETHIAPEN-2-EM-3-CARBOXYLIC ACIDS AND INTERMEDIATES FOR USE IN THE PRESENTATION OF THE PROCEDURE |
EP0038869A1 (en) * | 1980-04-30 | 1981-11-04 | Merck & Co. Inc. | Process for the preparation of 1-carbapenems, and intermediates for their preparation |
HU185493B (en) * | 1981-12-30 | 1985-02-28 | Richter Gedeon Vegyeszet | Process for producing new azabicyclo-bracket-3.2.0-bracket closedheptene derivatives |
US4552696A (en) * | 1982-04-09 | 1985-11-12 | Bristol-Myers Company | Carbapenem antibiotics |
US4536335A (en) * | 1982-06-18 | 1985-08-20 | Bristol-Myers Company | Carbapenem antibiotics |
-
1983
- 1983-03-22 CA CA000424190A patent/CA1198440A/en not_active Expired
- 1983-04-01 FR FR8305431A patent/FR2524888B1/en not_active Expired
- 1983-04-04 KR KR1019830001386A patent/KR880001055B1/en not_active IP Right Cessation
- 1983-04-05 NL NL8301193A patent/NL8301193A/en not_active Application Discontinuation
- 1983-04-05 IL IL68295A patent/IL68295A0/en not_active IP Right Cessation
- 1983-04-05 FI FI831135A patent/FI74009C/en not_active IP Right Cessation
- 1983-04-05 ES ES521224A patent/ES521224A0/en active Granted
- 1983-04-05 ZA ZA832411A patent/ZA832411B/en unknown
- 1983-04-06 AU AU13198/83A patent/AU567092B2/en not_active Ceased
- 1983-04-07 PT PT76518A patent/PT76518B/en not_active IP Right Cessation
- 1983-04-07 GB GB08309505A patent/GB2118183B/en not_active Expired
- 1983-04-07 SE SE8301928A patent/SE460197B/en not_active IP Right Cessation
- 1983-04-07 DK DK155983A patent/DK155983A/en not_active IP Right Cessation
- 1983-04-07 DE DE19833312517 patent/DE3312517A1/en active Granted
- 1983-04-07 HU HU831201A patent/HU190716B/en unknown
- 1983-04-07 IE IE800/83A patent/IE55225B1/en not_active IP Right Cessation
- 1983-04-07 BE BE0/210512A patent/BE896407A/en not_active IP Right Cessation
- 1983-04-07 LU LU84739A patent/LU84739A1/en unknown
- 1983-04-07 IT IT48061/83A patent/IT1168854B/en active
- 1983-04-07 GR GR71026A patent/GR78822B/el unknown
- 1983-04-08 JP JP58061072A patent/JPS58188887A/en active Granted
- 1983-04-08 OA OA57966A patent/OA07395A/en unknown
- 1983-04-08 AT AT0125583A patent/AT383126B/en not_active IP Right Cessation
- 1983-04-08 CH CH1915/83A patent/CH661927A5/en not_active IP Right Cessation
-
1987
- 1987-12-30 MY MY945/87A patent/MY8700945A/en unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
SE8303502D0 (en) | Carbapenem antibiotics | |
DK518683D0 (en) | PROCEDURE FOR THE PREPARATION OF 4 "EPI-9-DEOXO-9A-METHYL-9A-AZA-9A-HOMOERYTHROMYCINE OR PHARMACEUTICAL ACCEPTABLE ACID ADDITION SALTS AND INTERMEDIATES OF THE PROCEDURE | |
SE8502017L (en) | 1,4-DIHYDRO-4-OXONAFTYRIDINE DERIVATIVES AND SALTS THEREOF, PROCEDURE FOR PREPARING THESE EASY ANTI-BACTERIAL AGENTS INCLUDING THESE | |
SE7813352L (en) | NEW 2-PYRROLIDONE COMPOUNDS AND PROCEDURES FOR THE PREPARATION OF THE SAME | |
SE8305217D0 (en) | Carbapenem antibiotics | |
DK0393424T3 (en) | Process for the preparation of 2,7-diazabicyclo (3.3.0) octanes | |
SE8301929D0 (en) | NEW CARBAPEN NAME DERIVATIVES, PROCEDURES FOR PREPARING THEREOF AND NEW INTERMEDIATES FOR USE IN THESE PROCEDURES | |
SE8301928D0 (en) | NEW CARBAPEN MEMBER DERIVATIVES AND PROCEDURES FOR PREPARING THEREOF | |
ES2040856T3 (en) | A PROCEDURE FOR PREPARING A THIOPHENE COMPOUND. | |
SE8504538D0 (en) | CARBAPENEM ANTIBIOTICS | |
ES2039365T3 (en) | CARBAPENEM ANTIBIOTICS, A PROCEDURE FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM. | |
MA19841A1 (en) | PROCESS FOR THE PREPARATION OF NEW CEPHALOSPORIN DERIVATIVES FOR USE AS ANTIBIOTICS. | |
ATE119907T1 (en) | THIADIAZOLYLACETAMIDE CEPHEM DERIVATIVES. | |
PT79145B (en) | Process for preparing flavene and thioflavene derivatives and pharmaceutical composition containing them | |
IL64218A (en) | Heterobicyclic hydroxyimidates and thiolhydroximidates and carbamate ester derivatives thereof,their preparation and arthropodicidal and nematocidal compositions containing them | |
FI911616A (en) | SUBSTITUTES 3-TIA-ELLER 3-OXA-ALKYL-FLAVONER, FOER FARAND FOR DERASE FRAMSTAELLNING, DERAS ANVAENDNING, PAO DESSA FOERENINGAR BASERADE FOR CEILINGS SAMT MELLANPRODUKTER. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
NUG | Patent has lapsed |
Ref document number: 8301928-1 Effective date: 19941110 Format of ref document f/p: F |