SE7806711L - 7alfa-metoxi-7beta-(1,3-ditietan-2-karboxamido)-cefalosporansyraderivat - Google Patents

7alfa-metoxi-7beta-(1,3-ditietan-2-karboxamido)-cefalosporansyraderivat

Info

Publication number
SE7806711L
SE7806711L SE7806711A SE7806711A SE7806711L SE 7806711 L SE7806711 L SE 7806711L SE 7806711 A SE7806711 A SE 7806711A SE 7806711 A SE7806711 A SE 7806711A SE 7806711 L SE7806711 L SE 7806711L
Authority
SE
Sweden
Prior art keywords
ditietan
7alfa
7beta
carboxamido
methoxy
Prior art date
Application number
SE7806711A
Other languages
English (en)
Other versions
SE438338B (sv
Inventor
M Iwanami
T Maeda
Y Nagano
M Fujimoto
N Nagano
A Yamazaki
Original Assignee
Yamanouchi Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP52068699A external-priority patent/JPS5854157B2/ja
Priority claimed from JP9077277A external-priority patent/JPS5811956B2/ja
Priority claimed from JP53010772A external-priority patent/JPS6052714B2/ja
Application filed by Yamanouchi Pharma Co Ltd filed Critical Yamanouchi Pharma Co Ltd
Publication of SE7806711L publication Critical patent/SE7806711L/sv
Publication of SE438338B publication Critical patent/SE438338B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/57—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with a further substituent in position 7, e.g. cephamycines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SE7806711A 1977-06-10 1978-06-09 7alfa-metoxi-7beta-(1,3-ditietan-2-karboxamido)-cefalosporansyraderivat med antibakteriell verkan SE438338B (sv)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP52068699A JPS5854157B2 (ja) 1977-06-10 1977-06-10 セフアロスポリン化合物の新規誘導体ならびにその製造方法
JP9077277A JPS5811956B2 (ja) 1977-07-28 1977-07-28 新抗菌化合物
JP53010772A JPS6052714B2 (ja) 1978-02-02 1978-02-02 新規抗菌化合物

Publications (2)

Publication Number Publication Date
SE7806711L true SE7806711L (sv) 1978-12-11
SE438338B SE438338B (sv) 1985-04-15

Family

ID=27279078

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7806711A SE438338B (sv) 1977-06-10 1978-06-09 7alfa-metoxi-7beta-(1,3-ditietan-2-karboxamido)-cefalosporansyraderivat med antibakteriell verkan

Country Status (11)

Country Link
US (3) US4263432A (sv)
CA (1) CA1103659A (sv)
CH (1) CH648317A5 (sv)
DE (1) DE2824559C2 (sv)
DK (1) DK164224C (sv)
ES (4) ES470689A1 (sv)
FR (1) FR2405952A1 (sv)
IT (1) IT1159721B (sv)
MX (1) MX5137E (sv)
NL (2) NL185622C (sv)
SE (1) SE438338B (sv)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2824559C2 (de) * 1977-06-10 1985-01-10 Yamanouchi Pharmaceutical Co., Ltd., Tokio / Tokyo 7α-Methoxy-7β-(4-substituierte-methylen-1,3-dithietan-2-yl)-carboxamido-3-Δ↑3↑-cephem-4-carbonsäuren, Verfahren zu deren Herstellung sowie ihre Verwendung
GB1604738A (en) * 1977-07-28 1981-12-16 Yamanouchi Pharma Co Ltd 1,3-dithietane-2-carboxylic acid derivatives and the preparation thereof
EP0062118B1 (en) * 1981-04-03 1986-07-09 Nihon Nohyaku Co., Ltd. Process for producing 1,3-dithiol-2-ylidene malonates
ATE17245T1 (de) * 1981-04-03 1986-01-15 Nihon Nohyaku Co Ltd Verfahren zur herstellung von dialkylestern von 1,3-dithiol-2-ylidene-malonsaeure.
JPS6011917B2 (ja) * 1981-04-09 1985-03-28 山之内製薬株式会社 新規なセファロスポリン化合物
US5147871A (en) * 1986-07-03 1992-09-15 Hoffmann La-Roche, Inc. Anti-bacterial cephalosporin compounds
US5336768A (en) * 1988-05-24 1994-08-09 Hoffmann-La Roche Inc. Antibacterial cephalosporin compounds
CS273349B2 (en) * 1988-03-31 1991-03-12 Hoffmann La Roche Method of cephalosporin's new derivatives production
US5162523A (en) * 1989-07-21 1992-11-10 Hoffmann-La Roche Inc. Cephalosporin antibacterial compounds
US5159077A (en) * 1989-07-21 1992-10-27 Hoffmann-La Roche Inc. Penam antibacterial compounds
JP2566680B2 (ja) 1990-12-21 1996-12-25 塩野義製薬株式会社 ビニルチオ酢酸誘導体
JPH0713032B2 (ja) * 1993-03-19 1995-02-15 工業技術院長 ターシャリーブチルメチルエーテルの光脱水素二量化方法
US5811419A (en) * 1996-01-16 1998-09-22 Hoffmann-La Roche Inc. Isooxacephem-derivatives
US5883247A (en) * 1996-06-10 1999-03-16 Hoffmann-La Roche Inc. Preparation of cephem and isooxacephem derivatives
ITMI20010964A1 (it) 2001-05-10 2002-11-10 Acs Dobfar Spa Procedimento per l'ottenimento di composti utili per la produzione del cefotetan e nuovi composti cosi' ottenuti
ITMI20051085A1 (it) * 2005-06-10 2006-12-11 Acs Dobfar Spa Metodo di purificazione del cefotetan
ITMI20051115A1 (it) * 2005-06-14 2006-12-15 Acs Dobfar Spa Procedimento per l'ottenimento di cefotetan con resa elevata
WO2007122628A1 (en) * 2006-04-21 2007-11-01 Lupin Limited Improved process for preparation of highly pure cefotetan disodium
CN102161669A (zh) * 2011-02-21 2011-08-24 江苏济川制药有限公司 一种除去头孢替坦二钠中杂质△2-isomer的方法
CN102250125B (zh) * 2011-05-20 2013-10-16 海南合瑞制药股份有限公司 一种头孢替坦的制备方法
CN106478670B (zh) * 2016-08-30 2018-11-20 济川药业集团有限公司 一种头孢替坦酸的新结晶及其制备方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL29235A (en) 1967-01-05 1971-10-20 Bristol Myers Co 7-(pyridylthioacetamido)cephalosporanic acid derivatives and their preparation
CH527215A (de) * 1967-04-15 1972-08-31 Fujisawa Pharmaceutical Co Verfahren zur Herstellung von 3,7-disubstituierten Cephalosporinderivaten
AR205728A1 (es) * 1973-11-14 1976-05-31 Rhone Poulenc Sa Procedimiento para preparar ((dihidro-5,6-oxa)-(di) tiino-1,4-il-2) acetamido)-7 cefalosporina y sus sales
OA05033A (fr) * 1974-07-01 1980-12-31 Rhone Poulenc Ind Nouveaux dérivés de la céphalosporine et leur préparation.
JPS5119765A (en) * 1974-08-09 1976-02-17 Takeda Chemical Industries Ltd Aminochiazoorujudotaino seizoho
JPS5530714B2 (sv) * 1974-08-22 1980-08-13
US4182868A (en) * 1974-10-29 1980-01-08 Takeda Chemical Industries, Ltd. 7-Methoxycephalosporin derivatives
US4203899A (en) * 1974-12-19 1980-05-20 Takeda Chemical Industries, Ltd. Thiazolylacetamido compounds
DE2539214C2 (de) * 1975-09-03 1984-03-29 E.R. Squibb & Sons, Inc., 08540 Princeton, N.J. 7-Methoxythienyl-ureido-cephalosporin und dieses enthaltendes Arzneimittel
US4299829A (en) * 1976-03-12 1981-11-10 Fujisawa Pharmaceutical Co., Ltd. 2-Lower alkyl-7-substituted-2 or 3-cephem 4-carboxylic acid compounds
US4058609A (en) * 1976-06-28 1977-11-15 Smithkline Corporation 7-Dithioacetamido cephalosporins
DE2824559C2 (de) * 1977-06-10 1985-01-10 Yamanouchi Pharmaceutical Co., Ltd., Tokio / Tokyo 7α-Methoxy-7β-(4-substituierte-methylen-1,3-dithietan-2-yl)-carboxamido-3-Δ↑3↑-cephem-4-carbonsäuren, Verfahren zu deren Herstellung sowie ihre Verwendung
GB1604738A (en) * 1977-07-28 1981-12-16 Yamanouchi Pharma Co Ltd 1,3-dithietane-2-carboxylic acid derivatives and the preparation thereof

Also Published As

Publication number Publication date
DE2824559A1 (de) 1979-01-04
CA1103659A (en) 1981-06-23
CH648317A5 (de) 1985-03-15
US4263432A (en) 1981-04-21
DK164224C (da) 1992-10-19
DK258078A (da) 1979-01-23
ES470689A1 (es) 1979-09-01
FR2405952A1 (fr) 1979-05-11
IT1159721B (it) 1987-03-04
DK164224B (da) 1992-05-25
SE438338B (sv) 1985-04-15
USRE32491E (en) 1987-09-01
NL185622B (nl) 1990-01-02
NL7806208A (nl) 1978-12-12
DE2824559C2 (de) 1985-01-10
US4404373A (en) 1983-09-13
MX5137E (es) 1983-03-28
ES479167A1 (es) 1979-07-01
FR2405952B1 (sv) 1983-02-25
ES479166A1 (es) 1979-07-01
NL8901120A (nl) 1989-08-01
NL185622C (nl) 1990-06-01
ES479168A1 (es) 1979-07-01
IT7868369A0 (it) 1978-06-12

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