SE460521B - Permselektiv asymmetriskt membran samt foerfarande foer dess framstaellning - Google Patents

Permselektiv asymmetriskt membran samt foerfarande foer dess framstaellning

Info

Publication number: SE460521B
Authority: SE; Sweden
Prior art keywords: polymer; membrane; hydrophilic; hydrophobic; solvent
Prior art date: 1987-08-31

Application number

SE8703367A

Other languages

English (en)

Swedish (sv)

Other versions

SE8703367D0 (sv

SE8703367L (sv

Inventor

H J Goehl

R J Buck

Original Assignee

Gambro Dialysatoren

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-08-31

Filing date

1987-08-31

Publication date

1989-10-23

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=20369433&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SE460521(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1987-08-31 Application filed by Gambro Dialysatoren filed Critical Gambro Dialysatoren

1987-08-31 Priority to SE8703367A priority Critical patent/SE460521B/sv

1987-08-31 Publication of SE8703367D0 publication Critical patent/SE8703367D0/xx

1988-08-12 Priority to EP88113098A priority patent/EP0305787B2/de

1988-08-12 Priority to DE3875203T priority patent/DE3875203T3/de

1988-08-12 Priority to ES88113098T priority patent/ES2035194T5/es

1988-08-23 Priority to US07/235,373 priority patent/US4935141A/en

1988-08-30 Priority to JP63216192A priority patent/JP3047403B2/ja

1989-03-01 Publication of SE8703367L publication Critical patent/SE8703367L/

1989-10-23 Publication of SE460521B publication Critical patent/SE460521B/sv

Links

239000012528 membrane Substances 0.000 title claims description 85
238000000034 method Methods 0.000 title claims description 22
230000035699 permeability Effects 0.000 claims description 33
229920000642 polymer Polymers 0.000 claims description 30
239000002904 solvent Substances 0.000 claims description 26
IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 claims description 17
210000004369 blood Anatomy 0.000 claims description 14
239000008280 blood Substances 0.000 claims description 14
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 14
239000000203 mixture Substances 0.000 claims description 13
230000008569 process Effects 0.000 claims description 12
230000002209 hydrophobic effect Effects 0.000 claims description 11
239000000654 additive Substances 0.000 claims description 10
238000009792 diffusion process Methods 0.000 claims description 10
238000000108 ultra-filtration Methods 0.000 claims description 10
239000007788 liquid Substances 0.000 claims description 9
239000011148 porous material Substances 0.000 claims description 9
239000012510 hollow fiber Substances 0.000 claims description 8
229920001477 hydrophilic polymer Polymers 0.000 claims description 7
239000004952 Polyamide Substances 0.000 claims description 6
239000002158 endotoxin Substances 0.000 claims description 6
239000000835 fiber Substances 0.000 claims description 6
229920002647 polyamide Polymers 0.000 claims description 6
238000001556 precipitation Methods 0.000 claims description 6
238000001631 haemodialysis Methods 0.000 claims description 5
230000000322 hemodialysis Effects 0.000 claims description 5
229920001600 hydrophobic polymer Polymers 0.000 claims description 5
230000009467 reduction Effects 0.000 claims description 5
239000001913 cellulose Substances 0.000 claims description 4
229920002678 cellulose Polymers 0.000 claims description 4
238000001125 extrusion Methods 0.000 claims description 4
239000011888 foil Substances 0.000 claims description 4
102000009027 Albumins Human genes 0.000 claims description 3
108010088751 Albumins Proteins 0.000 claims description 3
235000011187 glycerol Nutrition 0.000 claims description 3
150000001298 alcohols Chemical class 0.000 claims description 2
239000003795 chemical substances by application Substances 0.000 claims description 2
238000001035 drying Methods 0.000 claims description 2
150000002314 glycerols Chemical class 0.000 claims description 2
229910052739 hydrogen Inorganic materials 0.000 claims description 2
239000001257 hydrogen Substances 0.000 claims description 2
238000005406 washing Methods 0.000 claims description 2
229920000036 polyvinylpyrrolidone Polymers 0.000 claims 4
235000013855 polyvinylpyrrolidone Nutrition 0.000 claims 4
ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 claims 3
238000002156 mixing Methods 0.000 claims 3
230000001376 precipitating effect Effects 0.000 claims 3
239000002202 Polyethylene glycol Substances 0.000 claims 2
229920001577 copolymer Polymers 0.000 claims 2
229920001223 polyethylene glycol Polymers 0.000 claims 2
229920001451 polypropylene glycol Polymers 0.000 claims 2
239000001267 polyvinylpyrrolidone Substances 0.000 claims 2
NIXOWILDQLNWCW-UHFFFAOYSA-N Acrylic acid Chemical class OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims 1
102100028967 HLA class I histocompatibility antigen, alpha chain G Human genes 0.000 claims 1
101710197836 HLA class I histocompatibility antigen, alpha chain G Proteins 0.000 claims 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 1
SECXISVLQFMRJM-UHFFFAOYSA-N N-Methylpyrrolidone Chemical compound CN1CCCC1=O SECXISVLQFMRJM-UHFFFAOYSA-N 0.000 claims 1
239000004697 Polyetherimide Substances 0.000 claims 1
239000004721 Polyphenylene oxide Substances 0.000 claims 1
239000004743 Polypropylene Substances 0.000 claims 1
125000000118 dimethyl group Chemical group [H]C([H])([H])* 0.000 claims 1
229920002239 polyacrylonitrile Polymers 0.000 claims 1
239000004417 polycarbonate Substances 0.000 claims 1
229920000515 polycarbonate Polymers 0.000 claims 1
229920000570 polyether Polymers 0.000 claims 1
229920001601 polyetherimide Polymers 0.000 claims 1
229920000151 polyglycol Polymers 0.000 claims 1
239000010695 polyglycol Substances 0.000 claims 1
-1 polypropylene Polymers 0.000 claims 1
229920001155 polypropylene Polymers 0.000 claims 1
229920000136 polysorbate Polymers 0.000 claims 1
229950008882 polysorbate Drugs 0.000 claims 1
229920002635 polyurethane Polymers 0.000 claims 1
239000004814 polyurethane Substances 0.000 claims 1
239000004800 polyvinyl chloride Substances 0.000 claims 1
229920000915 polyvinyl chloride Polymers 0.000 claims 1
239000002244 precipitate Substances 0.000 claims 1
150000003457 sulfones Chemical class 0.000 claims 1
238000009210 therapy by ultrasound Methods 0.000 claims 1
102000004169 proteins and genes Human genes 0.000 description 16
108090000623 proteins and genes Proteins 0.000 description 16
230000017531 blood circulation Effects 0.000 description 6
238000000502 dialysis Methods 0.000 description 6
238000001914 filtration Methods 0.000 description 6
239000000126 substance Substances 0.000 description 6
XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 5
239000004202 carbamide Substances 0.000 description 5
230000008859 change Effects 0.000 description 5
FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 4
238000004140 cleaning Methods 0.000 description 4
238000002615 hemofiltration Methods 0.000 description 4
210000000265 leukocyte Anatomy 0.000 description 4
DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 description 3
238000009826 distribution Methods 0.000 description 3
239000000706 filtrate Substances 0.000 description 3
239000012530 fluid Substances 0.000 description 3
238000000338 in vitro Methods 0.000 description 3
238000001727 in vivo Methods 0.000 description 3
238000004519 manufacturing process Methods 0.000 description 3
239000000463 material Substances 0.000 description 3
BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Substances [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 description 3
235000019333 sodium laurylsulphate Nutrition 0.000 description 3
238000001179 sorption measurement Methods 0.000 description 3
PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 2
ATJFFYVFTNAWJD-UHFFFAOYSA-N Tin Chemical compound [Sn] ATJFFYVFTNAWJD-UHFFFAOYSA-N 0.000 description 2
230000000996 additive effect Effects 0.000 description 2
230000000721 bacterilogical effect Effects 0.000 description 2
230000015572 biosynthetic process Effects 0.000 description 2
229910052799 carbon Inorganic materials 0.000 description 2
230000000694 effects Effects 0.000 description 2
238000011156 evaluation Methods 0.000 description 2
239000011780 sodium chloride Substances 0.000 description 2
241001552669 Adonis annua Species 0.000 description 1
241000894006 Bacteria Species 0.000 description 1
241000589539 Brevundimonas diminuta Species 0.000 description 1
OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
241001227124 Dialytes Species 0.000 description 1
YNPNZTXNASCQKK-UHFFFAOYSA-N Phenanthrene Natural products C1=CC=C2C3=CC=CC=C3C=CC2=C1 YNPNZTXNASCQKK-UHFFFAOYSA-N 0.000 description 1
241001499740 Plantago alpina Species 0.000 description 1
206010037660 Pyrexia Diseases 0.000 description 1
230000004913 activation Effects 0.000 description 1
239000000823 artificial membrane Substances 0.000 description 1
230000004888 barrier function Effects 0.000 description 1
230000008901 benefit Effects 0.000 description 1
102000015736 beta 2-Microglobulin Human genes 0.000 description 1
108010081355 beta 2-Microglobulin Proteins 0.000 description 1
230000005540 biological transmission Effects 0.000 description 1
210000004027 cell Anatomy 0.000 description 1
238000006243 chemical reaction Methods 0.000 description 1
230000000295 complement effect Effects 0.000 description 1
230000002950 deficient Effects 0.000 description 1
238000005534 hematocrit Methods 0.000 description 1
150000002500 ions Chemical class 0.000 description 1
239000010985 leather Substances 0.000 description 1
238000005259 measurement Methods 0.000 description 1
230000007246 mechanism Effects 0.000 description 1
229910052697 platinum Inorganic materials 0.000 description 1
230000010287 polarization Effects 0.000 description 1
229920006316 polyvinylpyrrolidine Polymers 0.000 description 1
229910052573 porcelain Inorganic materials 0.000 description 1
238000000746 purification Methods 0.000 description 1
230000001698 pyrogenic effect Effects 0.000 description 1
230000002787 reinforcement Effects 0.000 description 1
239000012488 sample solution Substances 0.000 description 1
238000007873 sieving Methods 0.000 description 1
239000007787 solid Substances 0.000 description 1
239000004575 stone Substances 0.000 description 1
238000012360 testing method Methods 0.000 description 1
GPRLSGONYQIRFK-MNYXATJNSA-N triton Chemical compound [3H+] GPRLSGONYQIRFK-MNYXATJNSA-N 0.000 description 1
238000002604 ultrasonography Methods 0.000 description 1

Classifications

- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D69/00—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
- B01D69/08—Hollow fibre membranes
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D67/00—Processes specially adapted for manufacturing semi-permeable membranes for separation processes or apparatus
- B01D67/0002—Organic membrane manufacture
- B01D67/0009—Organic membrane manufacture by phase separation, sol-gel transition, evaporation or solvent quenching
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D67/00—Processes specially adapted for manufacturing semi-permeable membranes for separation processes or apparatus
- B01D67/0002—Organic membrane manufacture
- B01D67/0009—Organic membrane manufacture by phase separation, sol-gel transition, evaporation or solvent quenching
- B01D67/0011—Casting solutions therefor
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D69/00—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
- B01D69/02—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor characterised by their properties
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D69/00—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
- B01D69/12—Composite membranes; Ultra-thin membranes
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D69/00—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
- B01D69/12—Composite membranes; Ultra-thin membranes
- B01D69/1216—Three or more layers
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2325/00—Details relating to properties of membranes
- B01D2325/02—Details relating to pores or porosity of the membranes
- B01D2325/022—Asymmetric membranes
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2325/00—Details relating to properties of membranes
- B01D2325/02—Details relating to pores or porosity of the membranes
- B01D2325/026—Sponge structure
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2325/00—Details relating to properties of membranes
- B01D2325/20—Specific permeability or cut-off range
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2325/00—Details relating to properties of membranes
- B01D2325/36—Hydrophilic membranes
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2325/00—Details relating to properties of membranes
- B01D2325/38—Hydrophobic membranes

Landscapes

Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Dispersion Chemistry (AREA)
Engineering & Computer Science (AREA)
Manufacturing & Machinery (AREA)
Separation Using Semi-Permeable Membranes (AREA)
External Artificial Organs (AREA)
Laminated Bodies (AREA)
Multicomponent Fibers (AREA)

SE8703367A 1987-08-31 1987-08-31 Permselektiv asymmetriskt membran samt foerfarande foer dess framstaellning SE460521B (sv)

Priority Applications (6)

Application Number	Priority Date	Filing Date	Title
SE8703367A SE460521B (sv)	1987-08-31	1987-08-31	Permselektiv asymmetriskt membran samt foerfarande foer dess framstaellning
EP88113098A EP0305787B2 (de)	1987-08-31	1988-08-12	Verfahren zur Herstellung einer permselektiven, asymmetrischen Membrane, verwendbar in der Hämodialyse und die so hergestellten Membrane
DE3875203T DE3875203T3 (de)	1987-08-31	1988-08-12	Verfahren zur Herstellung einer permselektiven, asymmetrischen Membrane, verwendbar in der Hämodialyse und die so hergestellten Membrane.
ES88113098T ES2035194T5 (es)	1987-08-31	1988-08-12	Un procedimiento para fabricar membranas asimetricas de permeabilidad selectiva adecuadas para hemodialisis y las membranas asi preparadas.
US07/235,373 US4935141A (en)	1987-08-31	1988-08-23	Selectively permeable asymmetric membranes suitable for use in hemodialysis and processes for manufacturing such membranes
JP63216192A JP3047403B2 (ja)	1987-08-31	1988-08-30	血液透析に適当な透過選択性不均斉膜および該膜の製造方法

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
SE8703367A SE460521B (sv)	1987-08-31	1987-08-31	Permselektiv asymmetriskt membran samt foerfarande foer dess framstaellning

Publications (3)

Publication Number	Publication Date
SE8703367D0 SE8703367D0 (sv)	1987-08-31
SE8703367L SE8703367L (sv)	1989-03-01
SE460521B true SE460521B (sv)	1989-10-23

Family

ID=20369433

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SE8703367A SE460521B (sv)	1987-08-31	1987-08-31	Permselektiv asymmetriskt membran samt foerfarande foer dess framstaellning

Country Status (6)

Country	Link
US (1)	US4935141A (de)
EP (1)	EP0305787B2 (de)
JP (1)	JP3047403B2 (de)
DE (1)	DE3875203T3 (de)
ES (1)	ES2035194T5 (de)
SE (1)	SE460521B (de)

Families Citing this family (80)

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1987
- 1987-08-31 SE SE8703367A patent/SE460521B/sv not_active IP Right Cessation
1988
- 1988-08-12 ES ES88113098T patent/ES2035194T5/es not_active Expired - Lifetime
- 1988-08-12 DE DE3875203T patent/DE3875203T3/de not_active Expired - Lifetime
- 1988-08-12 EP EP88113098A patent/EP0305787B2/de not_active Expired - Lifetime
- 1988-08-23 US US07/235,373 patent/US4935141A/en not_active Expired - Lifetime
- 1988-08-30 JP JP63216192A patent/JP3047403B2/ja not_active Expired - Lifetime

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Publication number	Publication date
DE3875203D1 (de)	1992-11-12
SE8703367D0 (sv)	1987-08-31
EP0305787B2 (de)	1997-09-03
SE8703367L (sv)	1989-03-01
ES2035194T3 (es)	1993-04-16
EP0305787A1 (de)	1989-03-08
US4935141A (en)	1990-06-19
JPH0194901A (ja)	1989-04-13
JP3047403B2 (ja)	2000-05-29
DE3875203T3 (de)	1997-11-13
ES2035194T5 (es)	1997-11-01
DE3875203T2 (de)	1993-02-25
EP0305787B1 (de)	1992-10-07

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