SE442304B - Forfarande for framstellning av en lett plasminkedja med ett serinproteasaktivt centrum - Google Patents
Forfarande for framstellning av en lett plasminkedja med ett serinproteasaktivt centrumInfo
- Publication number
- SE442304B SE442304B SE7710653A SE7710653A SE442304B SE 442304 B SE442304 B SE 442304B SE 7710653 A SE7710653 A SE 7710653A SE 7710653 A SE7710653 A SE 7710653A SE 442304 B SE442304 B SE 442304B
- Authority
- SE
- Sweden
- Prior art keywords
- procedure
- preparation
- active center
- protein active
- light plasma
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/6435—Plasmin (3.4.21.7), i.e. fibrinolysin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21007—Plasmin (3.4.21.7), i.e. fibrinolysin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US05/726,142 US4082612A (en) | 1976-09-24 | 1976-09-24 | Plasminogen activator complex |
Publications (2)
Publication Number | Publication Date |
---|---|
SE7710653L SE7710653L (sv) | 1978-03-25 |
SE442304B true SE442304B (sv) | 1985-12-16 |
Family
ID=24917422
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE7710653A SE442304B (sv) | 1976-09-24 | 1977-09-22 | Forfarande for framstellning av en lett plasminkedja med ett serinproteasaktivt centrum |
SE8301795A SE454048B (sv) | 1976-09-24 | 1983-03-30 | Forfarande for framstellning av ett komplex av streptokinas och en lett plasminkedja med ett serinproteasaktivt centrum |
SE8301794A SE454047B (sv) | 1976-09-24 | 1983-03-30 | Forfarande for framstellning av ett komplex av streptokinas och en lett plasminkedja med ett serinproteasaktivt centrum |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE8301795A SE454048B (sv) | 1976-09-24 | 1983-03-30 | Forfarande for framstellning av ett komplex av streptokinas och en lett plasminkedja med ett serinproteasaktivt centrum |
SE8301794A SE454047B (sv) | 1976-09-24 | 1983-03-30 | Forfarande for framstellning av ett komplex av streptokinas och en lett plasminkedja med ett serinproteasaktivt centrum |
Country Status (10)
Country | Link |
---|---|
US (1) | US4082612A (nl) |
JP (1) | JPS5352606A (nl) |
CA (1) | CA1094449A (nl) |
CH (2) | CH637991A5 (nl) |
DE (1) | DE2742529C2 (nl) |
DK (1) | DK421577A (nl) |
FR (1) | FR2365583A1 (nl) |
GB (1) | GB1533205A (nl) |
NL (1) | NL7710451A (nl) |
SE (3) | SE442304B (nl) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0028489B1 (en) * | 1979-11-05 | 1983-10-05 | Beecham Group Plc | Enzyme derivatives, and their preparation |
JPS58189122A (ja) * | 1982-04-30 | 1983-11-04 | Kaken Pharmaceut Co Ltd | 高脂血症予防治療剤 |
US4536391A (en) * | 1982-11-17 | 1985-08-20 | Otsuka Pharmaceutical Co. | Process for preparing urokinase complex |
JPS60136520A (ja) * | 1983-12-23 | 1985-07-20 | Otsuka Pharmaceut Co Ltd | フイブリン吸着性ウロキナ−ゼ複合体 |
GB8334498D0 (en) * | 1983-12-24 | 1984-02-01 | Beecham Group Plc | Compounds |
GB8334499D0 (en) * | 1983-12-24 | 1984-02-01 | Beecham Group Plc | Derivatives |
US4880776A (en) * | 1983-12-24 | 1989-11-14 | Beecham Group P.L.C. | Plasmin A-chain urokinase B-chain hybrid protein |
GB8400653D0 (en) * | 1984-01-11 | 1984-02-15 | Beecham Group Plc | Conjugates |
EP0156169B1 (en) * | 1984-02-29 | 1991-12-18 | Asahi Kasei Kogyo Kabushiki Kaisha | An aqueous solution of a tissue plasminogen activator dissolved therein at an increased concentration and a method |
US4774087A (en) * | 1987-08-14 | 1988-09-27 | Northwestern University | Micro-size fibrinolytic plasmin |
DE3833936C1 (nl) * | 1988-10-05 | 1989-09-21 | Henning Berlin Gmbh Chemie- Und Pharmawerk, 1000 Berlin, De | |
US7544500B2 (en) * | 1999-11-13 | 2009-06-09 | Talecris Biotherapeutics, Inc. | Process for the production of a reversibly inactive acidified plasmin composition |
US6969515B2 (en) | 1999-11-13 | 2005-11-29 | Talecris Biotherapeutics, Inc. | Method of thrombolysis by local delivery of reversibly inactivated acidified plasmin |
US6355243B1 (en) | 1999-11-13 | 2002-03-12 | Bayer Corporation | Method of thrombolysis by local delivery of active plasmin |
US6964764B2 (en) * | 1999-11-13 | 2005-11-15 | Talecris Biotherapeutics, Inc. | Method of thrombolysis by local delivery of reversibly inactivated acidified plasmin |
NZ589557A (en) * | 2008-06-04 | 2012-08-31 | Talecris Biotherapeutics Inc | Immobilised streptokinase, method and kit for preparing plasmin |
PL2403865T3 (pl) | 2009-03-03 | 2016-01-29 | Grifols Therapeutics Inc | Sposoby wytwarzania plazminogenu |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3865692A (en) * | 1974-01-11 | 1975-02-11 | Abbott Lab | Method for making highly potent plasminogen |
-
1976
- 1976-09-24 US US05/726,142 patent/US4082612A/en not_active Expired - Lifetime
-
1977
- 1977-08-16 CA CA284,760A patent/CA1094449A/en not_active Expired
- 1977-09-19 GB GB38933/77A patent/GB1533205A/en not_active Expired
- 1977-09-21 DE DE2742529A patent/DE2742529C2/de not_active Expired
- 1977-09-21 JP JP11276977A patent/JPS5352606A/ja active Pending
- 1977-09-22 FR FR7728611A patent/FR2365583A1/fr active Granted
- 1977-09-22 SE SE7710653A patent/SE442304B/xx not_active IP Right Cessation
- 1977-09-23 DK DK421577A patent/DK421577A/da not_active Application Discontinuation
- 1977-09-23 NL NL7710451A patent/NL7710451A/nl not_active Application Discontinuation
- 1977-09-23 CH CH1165677A patent/CH637991A5/de not_active IP Right Cessation
-
1982
- 1982-08-27 CH CH511282A patent/CH637992A5/de not_active IP Right Cessation
-
1983
- 1983-03-30 SE SE8301795A patent/SE454048B/sv not_active IP Right Cessation
- 1983-03-30 SE SE8301794A patent/SE454047B/sv not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
SE454047B (sv) | 1988-03-28 |
DE2742529C2 (de) | 1984-01-05 |
FR2365583B1 (nl) | 1981-07-10 |
SE8301795D0 (sv) | 1983-03-30 |
US4082612A (en) | 1978-04-04 |
FR2365583A1 (fr) | 1978-04-21 |
GB1533205A (en) | 1978-11-22 |
SE8301794D0 (sv) | 1983-03-30 |
SE454048B (sv) | 1988-03-28 |
SE7710653L (sv) | 1978-03-25 |
CA1094449A (en) | 1981-01-27 |
CH637992A5 (de) | 1983-08-31 |
SE8301795L (sv) | 1983-03-30 |
JPS5352606A (en) | 1978-05-13 |
DK421577A (da) | 1978-03-25 |
NL7710451A (nl) | 1978-03-29 |
DE2742529A1 (de) | 1978-03-30 |
CH637991A5 (de) | 1983-08-31 |
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Legal Events
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NUG | Patent has lapsed |
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