SE424990B - ANALOGY PROCEDURE FOR PREPARING 10,11-DIHYDRO-3-CARBOXY-CYPROHEPTADINE AND ITS N-OXIDE - Google Patents

ANALOGY PROCEDURE FOR PREPARING 10,11-DIHYDRO-3-CARBOXY-CYPROHEPTADINE AND ITS N-OXIDE

Info

Publication number
SE424990B
SE424990B SE7511792A SE7511792A SE424990B SE 424990 B SE424990 B SE 424990B SE 7511792 A SE7511792 A SE 7511792A SE 7511792 A SE7511792 A SE 7511792A SE 424990 B SE424990 B SE 424990B
Authority
SE
Sweden
Prior art keywords
dihydro
oxide
cyproheptadine
carboxy
preparing
Prior art date
Application number
SE7511792A
Other languages
Swedish (sv)
Other versions
SE7511792L (en
Inventor
D C Remy
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of SE7511792L publication Critical patent/SE7511792L/en
Publication of SE424990B publication Critical patent/SE424990B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Saccharide Compounds (AREA)

Abstract

10,11-Dihydro-3-carboxycyproheptadine and its esters, amides and N-oxide are disclosed to have pharmaceutical utility as appetite stimulants and as antihistaminic agents. Also disclosed are processes for the preparation of such compounds; pharmaceutical compositions comprising such, compounds; and methods of treatment comprising administering such compounds and compositions.
SE7511792A 1974-11-11 1975-10-21 ANALOGY PROCEDURE FOR PREPARING 10,11-DIHYDRO-3-CARBOXY-CYPROHEPTADINE AND ITS N-OXIDE SE424990B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US52267674A 1974-11-11 1974-11-11
US56328575A 1975-03-28 1975-03-28

Publications (2)

Publication Number Publication Date
SE7511792L SE7511792L (en) 1976-05-12
SE424990B true SE424990B (en) 1982-08-23

Family

ID=27060901

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7511792A SE424990B (en) 1974-11-11 1975-10-21 ANALOGY PROCEDURE FOR PREPARING 10,11-DIHYDRO-3-CARBOXY-CYPROHEPTADINE AND ITS N-OXIDE

Country Status (19)

Country Link
JP (1) JPS6011029B2 (en)
AR (1) AR211108A1 (en)
AT (1) AT352126B (en)
CA (1) CA1082177A (en)
CH (1) CH621114A5 (en)
DE (1) DE2550395C3 (en)
DK (1) DK474575A (en)
ES (1) ES442375A1 (en)
FI (1) FI59583C (en)
FR (1) FR2290203A1 (en)
IE (1) IE42220B1 (en)
IL (1) IL48365A (en)
LU (1) LU73771A1 (en)
NL (2) NL173398B (en)
NO (1) NO144422C (en)
NZ (1) NZ179080A (en)
PH (1) PH13443A (en)
SE (1) SE424990B (en)
YU (1) YU273475A (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4195091A (en) * 1978-11-15 1980-03-25 Merck & Co., Inc. Appetite stimulating pyrrolo[2,1-b][3]benzazepines
US4412999A (en) * 1982-04-14 1983-11-01 Merck & Co., Inc. Anti-emetic esters of cyproheptadine-3-carboxylic acid and structurally related compounds
US5250681A (en) * 1988-06-02 1993-10-05 Ajinomoto Co., Inc. Piperidine derivatives and hypotensives containing the same

Also Published As

Publication number Publication date
NO753562L (en) 1976-05-12
FI59583B (en) 1981-05-29
FI59583C (en) 1981-09-10
FR2290203A1 (en) 1976-06-04
NL7512384A (en) 1976-05-13
CA1082177A (en) 1980-07-22
PH13443A (en) 1980-04-23
JPS6011029B2 (en) 1985-03-22
NO144422C (en) 1981-08-26
FI752920A (en) 1976-05-12
IL48365A (en) 1978-10-31
NZ179080A (en) 1978-07-10
DE2550395C3 (en) 1979-08-09
NO144422B (en) 1981-05-18
DE2550395A1 (en) 1976-05-13
CH621114A5 (en) 1981-01-15
AR211108A1 (en) 1977-10-31
IE42220L (en) 1976-05-11
AT352126B (en) 1979-09-10
ATA843975A (en) 1979-02-15
ES442375A1 (en) 1977-08-16
YU273475A (en) 1983-04-27
NL173398C (en)
FR2290203B1 (en) 1980-05-30
DK474575A (en) 1976-05-12
IE42220B1 (en) 1980-07-02
DE2550395B2 (en) 1978-11-30
LU73771A1 (en) 1976-09-06
JPS5170769A (en) 1976-06-18
AU8605775A (en) 1977-05-05
IL48365A0 (en) 1975-12-31
NL173398B (en) 1983-08-16
SE7511792L (en) 1976-05-12

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