SE390304B - Analogiforfarande for framstellning av 4-hydroxi-5-etyl-6-fonylpyrimidin - Google Patents

Analogiforfarande for framstellning av 4-hydroxi-5-etyl-6-fonylpyrimidin

Info

Publication number: SE390304B
Authority: SE; Sweden
Prior art keywords: phonylpyrimidine; hydroxy; ethyl; preparation; analogical procedure
Prior art date: 1970-10-05

Application number

SE7410488A

Other languages

English (en)

Other versions

SE7410488L (sv

Inventor

G G Deangelis

H-J E Hess

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1970-10-05

Filing date

1971-10-04

Publication date

1976-12-13

1971-10-04 Application filed by Pfizer filed Critical Pfizer

1974-08-16 Publication of SE7410488L publication Critical patent/SE7410488L/xx

1976-12-13 Publication of SE390304B publication Critical patent/SE390304B/sv

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/30—Halogen atoms or nitro radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/34—One oxygen atom
- C07D239/36—One oxygen atom as doubly bound oxygen atom or as unsubstituted hydroxy radical
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/56—One oxygen atom and one sulfur atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D333/70—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pulmonology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

SE7410488A 1970-10-05 1971-10-04 Analogiforfarande for framstellning av 4-hydroxi-5-etyl-6-fonylpyrimidin SE390304B (sv)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US7821670A	1970-10-05	1970-10-05

Publications (2)

Publication Number	Publication Date
SE7410488L SE7410488L (sv)	1974-08-16
SE390304B true SE390304B (sv)	1976-12-13

Family

ID=22142671

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
SE7410488A SE390304B (sv)	1970-10-05	1971-10-04	Analogiforfarande for framstellning av 4-hydroxi-5-etyl-6-fonylpyrimidin
SE7112534-8A SE385885B (sv)	1970-10-05	1971-10-04	Foerfarande foer framstaellning av 4-amino-6-arylpyrimidinderivat

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
SE7112534-8A SE385885B (sv)	1970-10-05	1971-10-04	Foerfarande foer framstaellning av 4-amino-6-arylpyrimidinderivat

Country Status (16)

Country	Link
US (1)	US3707560A (sv)
JP (2)	JPS5648511B1 (sv)
AT (4)	AT316563B (sv)
AU (1)	AU465734B2 (sv)
BE (1)	BE773484A (sv)
CA (1)	CA988519A (sv)
CH (4)	CH554346A (sv)
DE (2)	DE2165962C2 (sv)
DK (1)	DK131858C (sv)
ES (4)	ES395676A1 (sv)
FI (1)	FI55502C (sv)
FR (1)	FR2110227B1 (sv)
GB (2)	GB1373536A (sv)
NL (1)	NL168511C (sv)
SE (2)	SE390304B (sv)
ZA (1)	ZA716615B (sv)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3895112A (en) *	1970-10-05	1975-07-15	Pfizer	Arylpyrimidines in the relaxation of smooth muscle
US3859288A (en) *	1970-10-05	1975-01-07	Pfizer	Arylpyrimidines - inhibitors of platelet aggregation and bronchodilators
US3908012A (en) *	1970-10-05	1975-09-23	Pfizer	Arylpyrimidines-inhibitors of platelet aggregation and bronchodilators
US3835132A (en) *	1972-02-01	1974-09-10	Shell Oil Co	Morpholino-piperazinyl pyrimidines
US3950525A (en) *	1973-06-19	1976-04-13	Pfizer Inc.	Relaxation of smooth muscle in a mammal
DE2343419A1 (de) *	1973-08-29	1975-03-13	Gruenenthal Chemie	Verfahren zur herstellung von pyrimidinderivaten
US4725600A (en) *	1984-07-13	1988-02-16	Fujisawa Pharmaceutical Co., Ltd.	Pyrimidine compounds having activity as a cardiotonic anti-hypertensive cerebrovascular vasodilator and anti-platelet aggregation agent
US4935516A (en) *	1988-01-29	1990-06-19	Ube Industries, Ltd.	Process for preparing 4-hydroxypyrimidine
JPH0625157B2 (ja) *	1988-01-29	1994-04-06	宇部興産株式会社	４―ヒドロキシピリミジン類の製造方法
DE3825647A1 (de) *	1988-07-28	1990-02-01	Geyer Gmbh & Co Christian	Vorrichtung zur befestigung eines elektrischen schaltgeraetes
DE3905364A1 (de) *	1989-02-22	1990-08-23	Hoechst Ag	Substituierte pyrimidin-derivate, verfahren zu ihrer herstellung und ihre verwendung als tool
EP1196411B1 (en)	1999-07-15	2003-09-17	Pharmacopeia, Inc.	Bradykinin b1 receptor antagonists
CN1642422A (zh) *	2002-03-15	2005-07-20	西巴特殊化学品控股有限公司	4－氨基嘧啶及其在表面抗菌处理中的应用
MXPA04011472A (es) *	2002-05-22	2005-02-14	Amgen Inc	Derivados de amino-piridina, piridina y piridazina para usarse como ligandos del receptor vaniloide para el tratamiento del dolor.
MXPA05010496A (es) *	2003-03-28	2005-11-16	Pharmacia & Upjohn Co Llc	Moduladores alostericos positivos del receptor de acetilcolina nicotinico.
EP1877400A1 (en) *	2005-04-15	2008-01-16	Amgen, Inc	Vanilloid receptor ligands and their use in treatments
JP2009164373A (ja) *	2008-01-08	2009-07-23	Toshiba Corp	半導体装置
US8883785B2 (en) *	2010-01-25	2014-11-11	Chdi Foundation, Inc.	Certain kynurenine-3-monooxygenase inhibitors, pharmaceutical compositions, and methods of use thereof
MX2014002459A (es)	2011-08-30	2014-04-10	Chdi Foundation Inc	Inhibidores de quinurenina-3-monooxigenasa, composiciones farmaceuticas y metodos de uso de los mismos.
EP3243515B1 (en)	2011-08-30	2019-10-16	CHDI Foundation, Inc.	Kynurenine-3-monooxygenase inhibitors, pharmaceutical compositions, and methods of use thereof
US10258621B2 (en)	2014-07-17	2019-04-16	Chdi Foundation, Inc.	Methods and compositions for treating HIV-related disorders

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3047462A (en) *	1959-03-06	1962-07-31	Lab Jacques Logeais Soc D Expl	Quinazolone anti-inflammatory composition

1970
- 1970-10-05 US US78216A patent/US3707560A/en not_active Expired - Lifetime
1971
- 1971-09-30 FI FI2734/71A patent/FI55502C/fi active
- 1971-10-01 DK DK480171A patent/DK131858C/da not_active IP Right Cessation
- 1971-10-02 DE DE2165962A patent/DE2165962C2/de not_active Expired
- 1971-10-02 DE DE2149249A patent/DE2149249C3/de not_active Expired
- 1971-10-04 ES ES395676A patent/ES395676A1/es not_active Expired
- 1971-10-04 CA CA124,312A patent/CA988519A/en not_active Expired
- 1971-10-04 SE SE7410488A patent/SE390304B/sv unknown
- 1971-10-04 ZA ZA716615A patent/ZA716615B/xx unknown
- 1971-10-04 GB GB3831673A patent/GB1373536A/en not_active Expired
- 1971-10-04 GB GB4615871A patent/GB1373535A/en not_active Expired
- 1971-10-04 SE SE7112534-8A patent/SE385885B/sv unknown
- 1971-10-05 AT AT00149/73A patent/AT316563B/de not_active IP Right Cessation
- 1971-10-05 AT AT605473A patent/AT317229B/de not_active IP Right Cessation
- 1971-10-05 BE BE773484A patent/BE773484A/xx not_active IP Right Cessation
- 1971-10-05 AT AT00148/73A patent/AT315856B/de not_active IP Right Cessation
- 1971-10-05 AT AT858071A patent/AT314540B/de not_active IP Right Cessation
- 1971-10-05 CH CH1532172A patent/CH554346A/fr not_active IP Right Cessation
- 1971-10-05 CH CH1521472A patent/CH554875A/fr not_active IP Right Cessation
- 1971-10-05 JP JP7823771A patent/JPS5648511B1/ja active Pending
- 1971-10-05 CH CH1452971A patent/CH554876A/fr not_active IP Right Cessation
- 1971-10-05 FR FR7135815A patent/FR2110227B1/fr not_active Expired
- 1971-10-05 CH CH772973A patent/CH542218A/fr not_active IP Right Cessation
- 1971-10-05 NL NLAANVRAGE7113670,A patent/NL168511C/xx not_active IP Right Cessation
- 1971-10-06 AU AU34259/71A patent/AU465734B2/en not_active Expired
1973
- 1973-11-02 ES ES420210A patent/ES420210A1/es not_active Expired
- 1973-11-02 ES ES420211A patent/ES420211A1/es not_active Expired
- 1973-11-02 ES ES420209A patent/ES420209A1/es not_active Expired
1980
- 1980-08-11 JP JP11016380A patent/JPS5636468A/ja active Granted

Also Published As

Publication number	Publication date
GB1373536A (en)	1974-11-13
FR2110227A1 (sv)	1972-06-02
DK131858B (da)	1975-09-15
NL7113670A (sv)	1972-04-07
DE2149249B2 (de)	1974-11-07
AT314540B (de)	1974-04-10
DE2165962A1 (de)	1972-08-31
AT316563B (de)	1974-06-15
CH554876A (fr)	1974-10-15
GB1373535A (en)	1974-11-13
SE385885B (sv)	1976-07-26
DE2149249A1 (de)	1972-04-13
NL168511B (nl)	1981-11-16
NL168511C (nl)	1982-04-16
JPS578107B2 (sv)	1982-02-15
ZA716615B (en)	1972-06-28
AU465734B2 (en)	1975-10-09
AT315856B (de)	1974-05-15
DK131858C (da)	1976-02-16
DE2149249C3 (de)	1975-07-03
SE7410488L (sv)	1974-08-16
AT317229B (de)	1974-08-26
CA988519A (en)	1976-05-04
JPS5636468A (en)	1981-04-09
FI55502C (fi)	1979-08-10
FR2110227B1 (sv)	1975-02-07
CH554346A (fr)	1974-09-30
CH542218A (fr)	1973-11-15
DE2165962C2 (de)	1982-05-13
US3707560A (en)	1972-12-26
BE773484A (fr)	1972-04-05
ES395676A1 (es)	1974-10-16
AU3425971A (en)	1973-04-12
CH554875A (fr)	1974-10-15
FI55502B (fi)	1979-04-30
JPS5648511B1 (sv)	1981-11-16
ES420211A1 (es)	1976-03-16
ES420209A1 (es)	1976-06-01
ES420210A1 (es)	1976-06-01

Publication	Publication Date	Title
SE393381B (sv)	1977-05-09	Analogiforfarande for framstellning av 8-azapurin - 6 - onderivat
SE383887B (sv)	1976-04-05	Analogiforfarande for framstellning av alfa-amino-cyklohexadienyl-alkylen-penicilliner
SE390304B (sv)	1976-12-13	Analogiforfarande for framstellning av 4-hydroxi-5-etyl-6-fonylpyrimidin
SE394678B (sv)	1977-07-04	Analogiforfarande for framstellning av pyridokinolinderivat
SE406197B (sv)	1979-01-29	Analogiforfarande for framstellning av 4-aminokinazolinderivat
NO138883C (no)	1978-11-29	Fremgangsmaate for fremstilling av oksiranforbindelser
SE400292B (sv)	1978-03-20	Forfarande for framstellning av benshydryl-3-karbamoyloximetyl-7-tienylacetamido-7-metoxidecefalosporanat
SE399701B (sv)	1978-02-27	Forfarande for framstellning av hydroxyalkyldiamin
SE394436B (sv)	1977-06-27	Forfarande for framstellning av 7-halogen-linkomyciner
SE380273B (sv)	1975-11-03	Forfarande for framstellning av tiopyrimidinderivat
SE385011B (sv)	1976-05-31	Forfarande for framstellning av alfa-linkosaminider
SE399069B (sv)	1978-01-30	Analogiforfarande for framstellning av triazolo-pyridino-isokinolin-derivat
SE395897B (sv)	1977-08-29	Forfarande for framstellning av 7beta-acylamido-3-metyl-cef-3-em-4-karbonsyror
SE397090B (sv)	1977-10-17	Forfarande for framstellning av hydroxipyrimidiner
SE405478B (sv)	1978-12-11	Forfarande for framstellning av alfa-sulfoacylcefalosporiner
SE408418B (sv)	1979-06-11	Forfarande for framstellning av 5-fluor-pyrimidiner
SE395699B (sv)	1977-08-22	Forfarande for framstellning av kinuklidin-kinolinderivat
SE388611B (sv)	1976-10-11	Analogiforfarande for framstellning av 1,4-bensodiazeponderivat
SE380795B (sv)	1975-11-17	Forfarande for framstellning av tiokarbamider
SE411759B (sv)	1980-02-04	Forfarande for framstellning av erytromycyliminforeningar
SE398114B (sv)	1977-12-05	Analogiforfarande for framstellning av aminoetrar
SE380520B (sv)	1975-11-10	Forfarande for framstellning av 1-cinnamylidenamino-3-bensylidenaminoguanidin
SE382046B (sv)	1976-01-12	Forfarande for framstellning av 1-aryloxi-2-propanol
SE404803B (sv)	1978-10-30	Analogiforfaranden for framstellning av pyrido-diazepiner
SE382051B (sv)	1976-01-12	Forfarande for framstellning av 3-sulfonamid-4-hydroxifenyl-2-piperidylkarbinoler