FR2110227B1 - - Google Patents

Info

Publication number: FR2110227B1
Authority: FR; France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

FR7135815A

Other versions

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Pfizer Inc

Original Assignee

Pfizer Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1970-10-05

Filing date

1971-10-05

Publication date

1975-02-07

1971-10-05 Application filed by Pfizer Inc filed Critical Pfizer Inc

1972-06-02 Publication of FR2110227A1 publication Critical patent/FR2110227A1/fr

1975-02-07 Application granted granted Critical

1975-02-07 Publication of FR2110227B1 publication Critical patent/FR2110227B1/fr

Status Expired legal-status Critical Current

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/30—Halogen atoms or nitro radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/34—One oxygen atom
- C07D239/36—One oxygen atom as doubly bound oxygen atom or as unsubstituted hydroxy radical
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/56—One oxygen atom and one sulfur atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D333/70—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pulmonology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

FR7135815A 1970-10-05 1971-10-05 Expired FR2110227B1 (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US7821670A	1970-10-05	1970-10-05

Publications (2)

Publication Number	Publication Date
FR2110227A1 FR2110227A1 (fr)	1972-06-02
FR2110227B1 true FR2110227B1 (fr)	1975-02-07

Family

ID=22142671

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FR7135815A Expired FR2110227B1 (fr)	1970-10-05	1971-10-05

Country Status (16)

Country	Link
US (1)	US3707560A (fr)
JP (2)	JPS5648511B1 (fr)
AT (4)	AT314540B (fr)
AU (1)	AU465734B2 (fr)
BE (1)	BE773484A (fr)
CA (1)	CA988519A (fr)
CH (4)	CH554875A (fr)
DE (2)	DE2149249C3 (fr)
DK (1)	DK131858C (fr)
ES (4)	ES395676A1 (fr)
FI (1)	FI55502C (fr)
FR (1)	FR2110227B1 (fr)
GB (2)	GB1373536A (fr)
NL (1)	NL168511C (fr)
SE (2)	SE385885B (fr)
ZA (1)	ZA716615B (fr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3859288A (en) *	1970-10-05	1975-01-07	Pfizer	Arylpyrimidines - inhibitors of platelet aggregation and bronchodilators
US3908012A (en) *	1970-10-05	1975-09-23	Pfizer	Arylpyrimidines-inhibitors of platelet aggregation and bronchodilators
US3895112A (en) *	1970-10-05	1975-07-15	Pfizer	Arylpyrimidines in the relaxation of smooth muscle
US3835132A (en) *	1972-02-01	1974-09-10	Shell Oil Co	Morpholino-piperazinyl pyrimidines
US3950525A (en) *	1973-06-19	1976-04-13	Pfizer Inc.	Relaxation of smooth muscle in a mammal
DE2343419A1 (de) *	1973-08-29	1975-03-13	Gruenenthal Chemie	Verfahren zur herstellung von pyrimidinderivaten
US4725600A (en) *	1984-07-13	1988-02-16	Fujisawa Pharmaceutical Co., Ltd.	Pyrimidine compounds having activity as a cardiotonic anti-hypertensive cerebrovascular vasodilator and anti-platelet aggregation agent
US4935516A (en) *	1988-01-29	1990-06-19	Ube Industries, Ltd.	Process for preparing 4-hydroxypyrimidine
JPH0625157B2 (ja) *	1988-01-29	1994-04-06	宇部興産株式会社	４―ヒドロキシピリミジン類の製造方法
DE3825647A1 (de) *	1988-07-28	1990-02-01	Geyer Gmbh & Co Christian	Vorrichtung zur befestigung eines elektrischen schaltgeraetes
DE3905364A1 (de) *	1989-02-22	1990-08-23	Hoechst Ag	Substituierte pyrimidin-derivate, verfahren zu ihrer herstellung und ihre verwendung als tool
JP2003505384A (ja) *	1999-07-15	2003-02-12	ファーマコピーア，インコーポレーティッド	ブラジキニンｂ１受容体アンタゴニスト
ES2290436T3 (es) *	2002-03-15	2008-02-16	Ciba Specialty Chemicals Holding Inc.	Uso de 4-aminopiridinas para el tratamiento antimicrobiano de superficies.
DE60335635D1 (de) *	2002-05-22	2011-02-17	Amgen Inc	Aminopyrimidin-derivate zur verwendung als vanilloid-rezeptor-liganden zur behandlung von schmerzen
WO2004085433A2 (fr) *	2003-03-28	2004-10-07	Pharmacia & Upjohn Company Llc	Modulateurs allosteriques positifs du recepteur nicotinique de l'acetylcholine
US20060235036A1 (en) *	2005-04-15	2006-10-19	Doherty Elizabeth M	Vanilloid receptor ligands and their use in treatments
JP2009164373A (ja) *	2008-01-08	2009-07-23	Toshiba Corp	半導体装置
CN102811620B (zh) *	2010-01-25	2015-03-25	Chdi基金会股份有限公司	一些犬尿氨酸-3-单加氧酶抑制剂、药物组合物及其使用方法
AU2012300246A1 (en)	2011-08-30	2014-03-06	Chdi Foundation, Inc.	Kynurenine-3-monooxygenase inhibitors, pharmaceutical compositions, and methods of use thereof
EA027451B1 (ru)	2011-08-30	2017-07-31	Схди Фаундейшн, Инк.	Ингибиторы кинуренин-3-монооксигеназы, фармацевтические композиции и их применение
SG11201700341PA (en)	2014-07-17	2017-02-27	Chdi Foundation Inc	Methods and compositions for treating hiv-related disorders

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3047462A (en) *	1959-03-06	1962-07-31	Lab Jacques Logeais Soc D Expl	Quinazolone anti-inflammatory composition

1970
- 1970-10-05 US US78216A patent/US3707560A/en not_active Expired - Lifetime
1971
- 1971-09-30 FI FI2734/71A patent/FI55502C/fi active
- 1971-10-01 DK DK480171A patent/DK131858C/da not_active IP Right Cessation
- 1971-10-02 DE DE2149249A patent/DE2149249C3/de not_active Expired
- 1971-10-02 DE DE2165962A patent/DE2165962C2/de not_active Expired
- 1971-10-04 ES ES395676A patent/ES395676A1/es not_active Expired
- 1971-10-04 CA CA124,312A patent/CA988519A/en not_active Expired
- 1971-10-04 GB GB3831673A patent/GB1373536A/en not_active Expired
- 1971-10-04 GB GB4615871A patent/GB1373535A/en not_active Expired
- 1971-10-04 SE SE7112534-8A patent/SE385885B/xx unknown
- 1971-10-04 ZA ZA716615A patent/ZA716615B/xx unknown
- 1971-10-04 SE SE7410488A patent/SE390304B/xx unknown
- 1971-10-05 AT AT858071A patent/AT314540B/de not_active IP Right Cessation
- 1971-10-05 AT AT605473A patent/AT317229B/de not_active IP Right Cessation
- 1971-10-05 CH CH1521472A patent/CH554875A/fr not_active IP Right Cessation
- 1971-10-05 NL NLAANVRAGE7113670,A patent/NL168511C/xx not_active IP Right Cessation
- 1971-10-05 AT AT00149/73A patent/AT316563B/de not_active IP Right Cessation
- 1971-10-05 CH CH1452971A patent/CH554876A/fr not_active IP Right Cessation
- 1971-10-05 CH CH772973A patent/CH542218A/fr not_active IP Right Cessation
- 1971-10-05 JP JP7823771A patent/JPS5648511B1/ja active Pending
- 1971-10-05 CH CH1532172A patent/CH554346A/fr not_active IP Right Cessation
- 1971-10-05 AT AT00148/73A patent/AT315856B/de not_active IP Right Cessation
- 1971-10-05 BE BE773484A patent/BE773484A/fr not_active IP Right Cessation
- 1971-10-05 FR FR7135815A patent/FR2110227B1/fr not_active Expired
- 1971-10-06 AU AU34259/71A patent/AU465734B2/en not_active Expired
1973
- 1973-11-02 ES ES420209A patent/ES420209A1/es not_active Expired
- 1973-11-02 ES ES420211A patent/ES420211A1/es not_active Expired
- 1973-11-02 ES ES420210A patent/ES420210A1/es not_active Expired
1980
- 1980-08-11 JP JP11016380A patent/JPS5636468A/ja active Granted

Also Published As

Publication number	Publication date
FI55502B (fi)	1979-04-30
DE2165962A1 (de)	1972-08-31
JPS5636468A (en)	1981-04-09
ZA716615B (en)	1972-06-28
DE2149249C3 (de)	1975-07-03
CH542218A (fr)	1973-11-15
SE385885B (sv)	1976-07-26
AT314540B (de)	1974-04-10
DK131858C (da)	1976-02-16
NL168511C (nl)	1982-04-16
DK131858B (da)	1975-09-15
DE2149249A1 (de)	1972-04-13
US3707560A (en)	1972-12-26
ES420209A1 (es)	1976-06-01
CH554875A (fr)	1974-10-15
BE773484A (fr)	1972-04-05
ES420211A1 (es)	1976-03-16
FI55502C (fi)	1979-08-10
AU3425971A (en)	1973-04-12
AU465734B2 (en)	1975-10-09
JPS5648511B1 (fr)	1981-11-16
AT317229B (de)	1974-08-26
CA988519A (en)	1976-05-04
GB1373536A (en)	1974-11-13
AT315856B (de)	1974-05-15
ES395676A1 (es)	1974-10-16
FR2110227A1 (fr)	1972-06-02
JPS578107B2 (fr)	1982-02-15
NL7113670A (fr)	1972-04-07
CH554346A (fr)	1974-09-30
NL168511B (nl)	1981-11-16
AT316563B (de)	1974-06-15
SE7410488L (fr)	1974-08-16
SE390304B (sv)	1976-12-13
CH554876A (fr)	1974-10-15
GB1373535A (en)	1974-11-13
ES420210A1 (es)	1976-06-01
DE2149249B2 (de)	1974-11-07
DE2165962C2 (de)	1982-05-13

Legal Events

Date	Code	Title	Description
1985-08-23	ST	Notification of lapse

Publication	Publication Date	Title
AR204384A1 (fr)	1976-02-06
JPS5648511B1 (fr)	1981-11-16
AU465454B2 (fr)	1975-09-25
ATA96471A (fr)	1973-02-15
AU2044470A (fr)	1972-03-30
AU1716970A (fr)	1972-01-06
AU1833270A (fr)	1972-02-10
AU2017870A (fr)	1972-03-23
AU2085370A (fr)	1972-04-13
AU2130570A (fr)	1972-04-27
JPS494113Y1 (fr)	1974-01-31
AU1086670A (fr)	1971-08-05
AU1004470A (fr)	1971-07-08
AU1689770A (fr)	1972-01-06
AU1343870A (fr)	1971-10-07
AU1789870A (fr)	1972-01-27
AU1832970A (fr)	1972-02-03
ATA672271A (fr)	1973-12-15
AU1841070A (fr)	1972-02-10
AU1872870A (fr)	1972-02-17
AU1879170A (fr)	1972-02-17
AU1881070A (fr)	1972-02-17
AU2131570A (fr)	1972-04-27
AU1064870A (fr)	1971-07-29
AU2144270A (fr)	1972-04-27