RU93045711A - Нейролептические пергидро-1h-пиридо(1,2-a)пиразины, способ их получения, фармацевтическая композиция, способ лечения - Google Patents

Нейролептические пергидро-1h-пиридо(1,2-a)пиразины, способ их получения, фармацевтическая композиция, способ лечения

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Publication number
RU93045711A
RU93045711A RU93045711/04A RU93045711A RU93045711A RU 93045711 A RU93045711 A RU 93045711A RU 93045711/04 A RU93045711/04 A RU 93045711/04A RU 93045711 A RU93045711 A RU 93045711A RU 93045711 A RU93045711 A RU 93045711A
Authority
RU
Russia
Prior art keywords
pirasins
pyrido
treatment
production
pharmaceutical composition
Prior art date
Application number
RU93045711/04A
Other languages
English (en)
Other versions
RU2090565C1 (ru
Inventor
Майкл Брайт Джин
Френсис Сигер Томас
Original Assignee
Пфайзер Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/661,791 external-priority patent/US5157034A/en
Application filed by Пфайзер Инк. filed Critical Пфайзер Инк.
Publication of RU93045711A publication Critical patent/RU93045711A/ru
Application granted granted Critical
Publication of RU2090565C1 publication Critical patent/RU2090565C1/ru

Links

Claims (1)

  1. Антипсихотические соединения, имеющие формулу I, приведенную в описании, образуют циклические имиды, 4-замещенные пиперидины или циклические сульфонамиды.
RU9193045711A 1991-02-27 1991-11-18 Рацемические или оптически активные пергидро-1h-пиридо(1,2-а) пиразины или их фармацевтически приемлемые соли и способ их получения RU2090565C1 (ru)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US661.791 1991-02-27
US07/661,791 US5157034A (en) 1991-02-27 1991-02-27 Neuroleptic perhydro-1H-pyrido[1,2-a]pyrazines
US661791 1991-02-27
PCT/US1991/008378 WO1992015580A1 (en) 1991-02-27 1991-11-18 NEUROLEPTIC PERHYDRO-1H-PYRIDO[1,2-a]PYRAZINES

Publications (2)

Publication Number Publication Date
RU93045711A true RU93045711A (ru) 1996-06-20
RU2090565C1 RU2090565C1 (ru) 1997-09-20

Family

ID=24655130

Family Applications (1)

Application Number Title Priority Date Filing Date
RU9193045711A RU2090565C1 (ru) 1991-02-27 1991-11-18 Рацемические или оптически активные пергидро-1h-пиридо(1,2-а) пиразины или их фармацевтически приемлемые соли и способ их получения

Country Status (24)

Country Link
US (1) US5157034A (ru)
EP (1) EP0573467B1 (ru)
JP (1) JP2546770B2 (ru)
KR (1) KR0163413B1 (ru)
AT (1) ATE123284T1 (ru)
AU (1) AU652422B2 (ru)
CA (2) CA2101518C (ru)
DE (2) DE9190206U1 (ru)
DK (1) DK0573467T3 (ru)
ES (1) ES2073914T3 (ru)
FI (3) FI105030B (ru)
HU (1) HU216637B (ru)
IE (1) IE67190B1 (ru)
IL (2) IL112325A (ru)
MX (1) MX9200803A (ru)
MY (1) MY108185A (ru)
NO (1) NO300847B1 (ru)
NZ (1) NZ241739A (ru)
PT (1) PT100160B (ru)
RU (1) RU2090565C1 (ru)
TW (1) TW207540B (ru)
WO (1) WO1992015580A1 (ru)
YU (1) YU48311B (ru)
ZA (1) ZA921405B (ru)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2101252C (en) * 1991-02-27 1998-02-17 Frank J. Urban Process for preparing trans-piperidine-2,5- dicarboxylates
US5719286A (en) * 1992-06-16 1998-02-17 Pfizer Inc. Process and intermediates for bis-aza-bicyclic anxiolytic agents
WO1996010570A1 (en) * 1994-09-30 1996-04-11 Pfizer Inc. NEUROLEPTIC 2,7-DISUBSTITUTED PERHYDRO-1H-PYRIDO[1,2-a]PYRAZINES
WO1996010571A1 (en) * 1994-09-30 1996-04-11 Pfizer Inc. 2,7-SUBSTITUTED OCTAHYDRO-1H-PYRIDO[1,2-a]PYRAZINE DERIVATIVES
US6231833B1 (en) 1999-08-05 2001-05-15 Pfizer Inc 2,7-substituted octahydro-1H-pyrido[1,2-A]pyrazine derivatives as ligands for serotonin receptors
PA8469101A1 (es) * 1998-04-09 2000-09-29 Pfizer Prod Inc Ligandos azabiciclicos de receptores 5ht1
UA62015C2 (en) * 1998-12-28 2003-12-15 Pfizer Prod Inc Benzoizoxazol derivatives, a pharmaceutical composition (variants) based thereon (variants) and a method for treatment (variants)
JP3910627B2 (ja) * 2003-03-12 2007-04-25 ファイザー・プロダクツ・インク ピリジルオキシメチルおよびベンゾイソオキサゾールのアザビシクロ環の誘導体
ES2563304T3 (es) * 2003-04-24 2016-03-14 Incyte Holdings Corporation Derivados azaespiro alcano como inhibidores de metaloproteasas
WO2007143600A2 (en) * 2006-06-05 2007-12-13 Incyte Corporation Sheddase inhibitors combined with cd30-binding immunotherapeutics for the treatment of cd30 positive diseases
JP6440625B2 (ja) 2012-11-14 2018-12-19 ザ・ジョンズ・ホプキンス・ユニバーシティー 精神***病を処置するための方法および組成物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4681938A (en) * 1984-08-27 1987-07-21 Ciba-Geigy Corporation Novel polycyclic hydrazones of rifamycins, their manufacture, and their pharmaceutical compositions for treating tuberculosis
US4831031A (en) * 1988-01-22 1989-05-16 Pfizer Inc. Aryl piperazinyl-(C2 or C4) alkylene heterocyclic compounds having neuroleptic activity
US4957916A (en) * 1988-08-05 1990-09-18 Janssen Pharmaceutica N.V. Antipsychotic 3-piperazinylbenzazole derivatives
WO1990008148A1 (en) * 1989-01-23 1990-07-26 Pfizer Inc. Bis-aza-bicyclic anxiolytic agents

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