DK0409435T3 - Heteroarylpiperaziner som antipsykotiske midler - Google Patents

Heteroarylpiperaziner som antipsykotiske midler

Info

Publication number
DK0409435T3
DK0409435T3 DK90307166.0T DK90307166T DK0409435T3 DK 0409435 T3 DK0409435 T3 DK 0409435T3 DK 90307166 T DK90307166 T DK 90307166T DK 0409435 T3 DK0409435 T3 DK 0409435T3
Authority
DK
Denmark
Prior art keywords
heteroberl
piperazines
antipsychotics
compounds
psychosis
Prior art date
Application number
DK90307166.0T
Other languages
English (en)
Inventor
Harry R Howard
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of DK0409435T3 publication Critical patent/DK0409435T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
DK90307166.0T 1989-07-07 1990-06-29 Heteroarylpiperaziner som antipsykotiske midler DK0409435T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1989/002954 WO1991000863A1 (en) 1989-07-07 1989-07-07 Heteroaryl piperazine antipsychotic agents

Publications (1)

Publication Number Publication Date
DK0409435T3 true DK0409435T3 (da) 1994-11-21

Family

ID=22215102

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90307166.0T DK0409435T3 (da) 1989-07-07 1990-06-29 Heteroarylpiperaziner som antipsykotiske midler

Country Status (11)

Country Link
EP (1) EP0409435B1 (da)
JP (1) JPH0717633B2 (da)
AT (1) ATE113282T1 (da)
CA (1) CA2020611A1 (da)
DE (1) DE69013601T2 (da)
DK (1) DK0409435T3 (da)
ES (1) ES2062374T3 (da)
FI (1) FI920023A0 (da)
IE (1) IE63134B1 (da)
PT (1) PT94608A (da)
WO (1) WO1991000863A1 (da)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0635506A4 (en) * 1993-02-04 1995-04-12 Meiji Seika Co CONNECTION WITH ANTIPSYCHOTIC EFFECT.
FR2761067B1 (fr) * 1997-03-20 1999-04-23 Synthelabo Derives de quinolein-2-(1h)-one, leur preparation et leur application en therapeutique
BR0314393A (pt) * 2002-09-17 2005-07-19 Warner Lambert Co Piperazinas heterocìclicas substituìdas para o tratamento de esquizofrenia
AU2003260882A1 (en) * 2002-09-26 2004-04-19 Warner-Lambert Company Llc Heterocyclic substituted piperazines for the treatment of schizophrenia
US7160888B2 (en) * 2003-08-22 2007-01-09 Warner Lambert Company Llc [1,8]naphthyridin-2-ones and related compounds for the treatment of schizophrenia
TWI320783B (en) 2005-04-14 2010-02-21 Otsuka Pharma Co Ltd Heterocyclic compound
RS53599B1 (en) 2005-05-10 2015-02-27 Intermune, Inc. PIRIDON DERIVATIVES FOR STRESS MODULATION OF ACTIVATED PROTEIN KINASE SYSTEMS
AR055203A1 (es) 2005-08-31 2007-08-08 Otsuka Pharma Co Ltd Derivados de benzotiofeno con propiedades antipsicoticas
WO2008015516A1 (en) * 2006-07-28 2008-02-07 Pfizer Products Inc. Fused tricyclic heterocycles for the treatment of schizophrenia
EP2094686A1 (en) 2006-09-26 2009-09-02 Glaxo Group Limited 5-{2-[4-(2-methyl-5-quinolinyl)-l-piperidinyl]ethyl} quinolinone derivatives as 5ht1a receptor modulators for treating sexual dysfunction, cognition impairement, psychotic disorders, anxiety, depression, etc.
ES2567283T3 (es) 2008-06-03 2016-04-21 Intermune, Inc. Compuestos y métodos para tratar trastornos inflamatorios y fibróticos
WO2010151689A1 (en) 2009-06-25 2010-12-29 Alkermes, Inc. Heterocyclic compounds for the treatment of neurological and psychological disorders
EP2445343B1 (en) 2009-06-25 2021-08-04 Alkermes Pharma Ireland Limited Prodrugs of nh-acidic compounds
CN112451477B (zh) 2011-03-18 2022-12-30 奥克梅斯制药爱尔兰有限公司 包含脱水山梨糖醇酯的药物组合物
US8969337B2 (en) 2011-12-15 2015-03-03 Alkermes Pharma Ireland Limited Prodrugs of secondary amine compounds
NZ630703A (en) 2012-03-19 2017-02-24 Alkermes Pharma Ireland Ltd Pharmaceutical compositions comprising glycerol esters
AU2013235519C1 (en) 2012-03-19 2018-04-26 Alkermes Pharma Ireland Limited Pharmaaceutical compositions comprising fatty acid esters
JP6333802B2 (ja) 2012-03-19 2018-05-30 アルカームス ファーマ アイルランド リミテッド ベンジルアルコールを含む医薬組成物
NZ730571A (en) 2012-09-19 2018-12-21 Alkermes Pharma Ireland Ltd Pharmaceutical compositions having improved storage stability
AR092742A1 (es) 2012-10-02 2015-04-29 Intermune Inc Piridinonas antifibroticas
EP3610890A1 (en) 2012-11-14 2020-02-19 The Johns Hopkins University Methods and compositions for treating schizophrenia
WO2015143145A1 (en) 2014-03-20 2015-09-24 Alkermes Pharma Ireland Limited Aripiprazole formulations having increased injection speeds
JP5714152B2 (ja) * 2014-03-26 2015-05-07 江蘇恒誼薬業有限公司 アラルキルピペリジン（又はピペラジン）誘導体及びその統合失調症治療のための使用
CN110452216B (zh) 2014-04-02 2022-08-26 英特穆恩公司 抗纤维化吡啶酮类
WO2019173230A1 (en) 2018-03-05 2019-09-12 Alkermes Pharma Ireland Limited Aripiprazole dosing strategy

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4721721A (en) * 1984-12-18 1988-01-26 Rorer Pharmaceutical Corporation 6-(4-thiazole) compounds, cardiotonic compositions including the same, and their uses
MX173362B (es) * 1987-03-02 1994-02-23 Pfizer Compuestos de piperazinil heterociclicos y procedimiento para su preparacion
ES2052675T3 (es) * 1987-11-20 1994-07-16 Hoechst Roussel Pharma 3-(4-piperazinil-sustituido en 1)butil)-4-tiazolidinonas, un procedimiento para su preparacion y su uso como medicamentos.
US4880930A (en) * 1987-11-30 1989-11-14 New James S Psychotropic acyclic amide derivatives
US4831031A (en) * 1988-01-22 1989-05-16 Pfizer Inc. Aryl piperazinyl-(C2 or C4) alkylene heterocyclic compounds having neuroleptic activity

Also Published As

Publication number Publication date
JPH0717633B2 (ja) 1995-03-01
EP0409435A1 (en) 1991-01-23
ES2062374T3 (es) 1994-12-16
FI920023A0 (fi) 1992-01-03
IE63134B1 (en) 1995-03-22
DE69013601D1 (de) 1994-12-01
DE69013601T2 (de) 1995-03-02
PT94608A (pt) 1991-03-20
JPH0344388A (ja) 1991-02-26
EP0409435B1 (en) 1994-10-26
CA2020611A1 (en) 1991-01-08
ATE113282T1 (de) 1994-11-15
IE902450A1 (en) 1991-02-13
WO1991000863A1 (en) 1991-01-24

Similar Documents

Publication Publication Date Title
DK0409435T3 (da) Heteroarylpiperaziner som antipsykotiske midler
ES2058614T3 (es) 1,2-ciclohexilaminoarilaminadas utiles como agentes analgesicos.
MX9102407A (es) 4 arilpiperazinas y 4-arilpiperidinas novedosas.
ATE168992T1 (de) 7-substituierte-9-substituierte glycylamido-6- demethyl-6-deoxytetracycline
ES2161220T3 (es) 9-((glicil sustituido)amido)-6-desmetil-6-desoxitetraciclinas como agentes antibioticos.
FI890311A (fi) Kemiska foereningar.
ATE144498T1 (de) Herstellung von substituierten piperidinen
SE8404065D0 (sv) Novel biologically active compounds
ES2104174T3 (es) Derivados de bencilamino, bencilamido y bencilimido ciclicos utilizados como agentes antipsicoticos.
FI901277A0 (fi) 2,5,6,7-tetranor-4,8-inter-m-fenylen pg1z-derivativ.
DE69222143T2 (de) Indanderivate
IT1241927B (it) 3'-deamino-4'-deossi-4'-amino-8-fluoroantra- cicline processi per la loro preparazione e composizioni farmaceutiche che le contengono
ATE97130T1 (de) 13-brom und 13, 14-dibrom-ergoline, ihre herstellung und verwendung in arzneimitteln.
EP0412941A3 (en) Phospholipids for the treatment of multiple sclerosis