RU93004445A - Новые 2-циано 3-гидроксиенамидные производные, способ их получения, их применение в качестве медикаментов, содержащие их фармацевтические композиции и новые полученные промежуточные продукты - Google Patents

Новые 2-циано 3-гидроксиенамидные производные, способ их получения, их применение в качестве медикаментов, содержащие их фармацевтические композиции и новые полученные промежуточные продукты

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Publication number
RU93004445A
RU93004445A RU93004445/04A RU93004445A RU93004445A RU 93004445 A RU93004445 A RU 93004445A RU 93004445/04 A RU93004445/04 A RU 93004445/04A RU 93004445 A RU93004445 A RU 93004445A RU 93004445 A RU93004445 A RU 93004445A
Authority
RU
Russia
Prior art keywords
new
hydroxyenamide
cyano
derivatives
medication
Prior art date
Application number
RU93004445/04A
Other languages
English (en)
Other versions
RU2112772C1 (ru
Inventor
Бартлетт Роберт
Пулкей Давид
Энн Кюо Элизабет
Шлейербах Рудольф
Шваб Вильфрид
Original Assignee
Руссель - Юклаф
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB929200275A external-priority patent/GB9200275D0/en
Application filed by Руссель - Юклаф filed Critical Руссель - Юклаф
Publication of RU93004445A publication Critical patent/RU93004445A/ru
Application granted granted Critical
Publication of RU2112772C1 publication Critical patent/RU2112772C1/ru

Links

Claims (1)

  1. Изобретение относится к новым 2-циано-3-гидроксиенамидным производным, к способу их получения и фармацевтической композиции на их основе.
RU93004445A 1992-01-08 1993-01-06 Производные 2-циано-3-гидроксиенамидов, способы их получения, фармацевтическая композиция на их основе RU2112772C1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB929200275A GB9200275D0 (en) 1992-01-08 1992-01-08 Chemical compounds
GB9200275.7 1992-01-08

Publications (2)

Publication Number Publication Date
RU93004445A true RU93004445A (ru) 1995-08-20
RU2112772C1 RU2112772C1 (ru) 1998-06-10

Family

ID=10708234

Family Applications (1)

Application Number Title Priority Date Filing Date
RU93004445A RU2112772C1 (ru) 1992-01-08 1993-01-06 Производные 2-циано-3-гидроксиенамидов, способы их получения, фармацевтическая композиция на их основе

Country Status (22)

Country Link
US (1) US5308865A (ru)
EP (1) EP0551230B1 (ru)
JP (1) JP3145824B2 (ru)
KR (1) KR100276182B1 (ru)
CN (1) CN1034499C (ru)
AT (1) ATE125252T1 (ru)
AU (1) AU652088B2 (ru)
BR (1) BR9300035A (ru)
CA (1) CA2086908C (ru)
CZ (1) CZ285586B6 (ru)
DE (1) DE69300261T2 (ru)
DK (1) DK0551230T3 (ru)
ES (1) ES2074916T3 (ru)
FI (1) FI111361B (ru)
GB (1) GB9200275D0 (ru)
HU (1) HU215843B (ru)
IL (1) IL104225A (ru)
NO (1) NO179444C (ru)
NZ (1) NZ245631A (ru)
RU (1) RU2112772C1 (ru)
TW (1) TW234116B (ru)
ZA (1) ZA93134B (ru)

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WO1994024095A1 (en) * 1993-04-16 1994-10-27 Abbott Laboratories Immunosuppressive agents
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GB9322781D0 (en) * 1993-11-04 1993-12-22 Roussel Lab Ltd Aromatic amides
US5700823A (en) * 1994-01-07 1997-12-23 Sugen, Inc. Treatment of platelet derived growth factor related disorders such as cancers
US6335356B1 (en) 1994-01-07 2002-01-01 Sugen, Inc. Method of treating a patient by parenteral administration of a lipophilic compound
US5610173A (en) * 1994-01-07 1997-03-11 Sugen, Inc. Formulations for lipophilic compounds
US5721277A (en) * 1995-04-21 1998-02-24 Sugen, Inc. Compounds and methods for inhibiting hyper-proliferative cell growth
GB9520092D0 (en) * 1995-10-02 1995-12-06 Hoechst Roussel Ltd Chemical compounds
DE19539638A1 (de) * 1995-10-25 1997-04-30 Hoechst Ag Die Verwendung von Isoxazol- und Crotonsäureamidderivaten zur Behandlung von Krebserkrankungen
DE19547648A1 (de) * 1995-12-20 1997-06-26 Hoechst Ag Zubereitung, enthaltend High Density Lipoproteine und Crotonsäureamidderivate
US5856330A (en) * 1996-07-31 1999-01-05 Hoechst Aktiengesellschaft Use of xanthine derivatives for the inhibition of dephosphorylation of cofilin
US5981536A (en) * 1996-07-31 1999-11-09 Hoechst Aktiengesellschaft Use of xanthine derivatives for the modulation of apoptosis
US6011051A (en) * 1996-07-31 2000-01-04 Hoechst Aktiengesellschaft Use of isoxazole and crotonamide derivatives for the modulation of apoptosis
DE19702988A1 (de) 1997-01-28 1998-07-30 Hoechst Ag Isoxazol- und Crotonsäureamidderivate und deren Verwendung als Arzneimittel und Diagnostika
DE19711800A1 (de) * 1997-03-21 1998-09-24 Hoechst Ag Verlängerung der Expression von transgenen Proteinen durch immunmodulierende Behandlung
US6316479B1 (en) 1997-05-19 2001-11-13 Sugen, Inc. Isoxazole-4-carboxamide compounds active against protein tryosine kinase related disorders
US6303652B1 (en) * 1998-08-21 2001-10-16 Hughes Institute BTK inhibitors and methods for their identification and use
MXPA00010150A (es) * 1998-04-17 2002-05-14 Parker Hughes Inst Inhibidores de btk y metodos para su identificacion y uso.
CN1646122A (zh) * 2002-04-16 2005-07-27 藤泽药品工业株式会社 用于预防和/或治疗慢性排斥的药物
EP1609778A1 (en) * 2003-03-24 2005-12-28 Astellas Pharma Inc. Process for production of 2-cyano-3-hydroxy-n-(4-tri- fluoromethylphenyl)hept-2-en-6-ynamide and process for production of polymorphs thereof
CA2558596A1 (en) * 2004-03-05 2005-09-15 Astellas Pharma Inc. Anti fk778 antibodies and high sensitive immunoassay methods
DE102005017592A1 (de) * 2005-04-16 2006-10-19 Lindner, Jürgen, Dr. med. Darreichungsformen und Kombinationspräparate von Pyrimidinbiosyntheseinhibitoren zur Erzielung zusätzlicher Wirkungen auf das Immunsystem
NZ601350A (en) * 2007-11-16 2013-08-30 Abbvie Inc Method of treating arthritis
CN103179962B (zh) 2010-10-29 2017-03-22 艾格埃克斯制药有限公司 丙二腈酰胺类似物在神经病理性疼痛中的用途
CN105916522A (zh) 2013-11-22 2016-08-31 建新公司 用于治疗神经变性疾病的新方法
CN112979509B (zh) * 2021-03-10 2022-04-22 江西师范大学 一种三氟甲磺酰基炔酰胺类化合物及其制备方法和用途

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FR484223A (fr) * 1916-03-21 1917-09-14 Zenith Carburateur Soc Du Perfectionnements aux carburateurs de moteurs à explosions
NL186239B (nl) * 1975-06-05 Hoechst Ag Werkwijze voor de bereiding van een geneesmiddel met antiflogistische en/of analgetische werking, alsmede werkwijze voor de bereiding van een 2-hydroxyethylideencyaanazijnzuuranilide geschikt voor toepassing bij deze werkwijze.
DE2555789A1 (de) * 1975-12-11 1977-07-07 Hoechst Ag Neue cyanessigsaeureanilid-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende mittel
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AU649421B2 (en) * 1990-05-18 1994-05-26 Sanofi-Aventis Deutschland Gmbh Isoxazole-4-carboxamides and hydroxyalkylidene-cyanoacetamides, drugs containing these compounds and use of such drugs
IL99811A (en) * 1990-10-30 1996-03-31 Roussel Uclaf 3-Cycloalkyl-propanamides, tautomeric forms of these, their salts, method of preparation, use as drugs and preparations containing them

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