RU2002108594A - Pharmaceutical solid composition having antiarrhythmic activity, and a method for its preparation - Google Patents
Pharmaceutical solid composition having antiarrhythmic activity, and a method for its preparationInfo
- Publication number
- RU2002108594A RU2002108594A RU2002108594/14A RU2002108594A RU2002108594A RU 2002108594 A RU2002108594 A RU 2002108594A RU 2002108594/14 A RU2002108594/14 A RU 2002108594/14A RU 2002108594 A RU2002108594 A RU 2002108594A RU 2002108594 A RU2002108594 A RU 2002108594A
- Authority
- RU
- Russia
- Prior art keywords
- starch
- mass
- asparaginate
- magnesium
- solid composition
- Prior art date
Links
- 239000008247 solid mixture Substances 0.000 title claims 4
- 230000003288 anthiarrhythmic Effects 0.000 title claims 3
- 229920002472 Starch Polymers 0.000 claims 7
- 239000008107 starch Substances 0.000 claims 7
- 235000019698 starch Nutrition 0.000 claims 7
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 claims 6
- GUBGYTABKSRVRQ-UUNJERMWSA-N Lactose Natural products O([C@@H]1[C@H](O)[C@H](O)[C@H](O)O[C@@H]1CO)[C@H]1[C@@H](O)[C@@H](O)[C@H](O)[C@H](CO)O1 GUBGYTABKSRVRQ-UUNJERMWSA-N 0.000 claims 3
- 150000001875 compounds Chemical class 0.000 claims 3
- GUBGYTABKSRVRQ-XLOQQCSPSA-N lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 claims 3
- 239000008101 lactose Substances 0.000 claims 3
- 229960000259 magnesium asparaginate Drugs 0.000 claims 3
- 235000019359 magnesium stearate Nutrition 0.000 claims 3
- ZHYLJCKTXNWNPJ-CEOVSRFSSA-L magnesium;(2S)-2,4-diamino-4-oxobutanoate Chemical compound [Mg+2].[O-]C(=O)[C@@H](N)CC(N)=O.[O-]C(=O)[C@@H](N)CC(N)=O ZHYLJCKTXNWNPJ-CEOVSRFSSA-L 0.000 claims 3
- 229960003193 potassium asparaginate Drugs 0.000 claims 3
- NRFNNNBFDIFBLS-DKWTVANSSA-M potassium;(2S)-2,4-diamino-4-oxobutanoate Chemical compound [K+].[O-]C(=O)[C@@H](N)CC(N)=O NRFNNNBFDIFBLS-DKWTVANSSA-M 0.000 claims 3
- 239000000126 substance Substances 0.000 claims 3
- 239000000454 talc Substances 0.000 claims 3
- 229910052623 talc Inorganic materials 0.000 claims 3
- 238000010410 dusting Methods 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- 235000012222 talc Nutrition 0.000 claims 2
- 238000007908 dry granulation Methods 0.000 claims 1
- 238000001035 drying Methods 0.000 claims 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 claims 1
- 239000011777 magnesium Substances 0.000 claims 1
- 229910052749 magnesium Inorganic materials 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 claims 1
- 239000011591 potassium Substances 0.000 claims 1
- 229910052700 potassium Inorganic materials 0.000 claims 1
- 239000002994 raw material Substances 0.000 claims 1
- 238000005550 wet granulation Methods 0.000 claims 1
Claims (4)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
RU2002108594A RU2207853C1 (en) | 2002-04-04 | 2002-04-04 | Pharmaceutical solid composition eliciting anti- arrhythmic activity and method for its preparing |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
RU2002108594A RU2207853C1 (en) | 2002-04-04 | 2002-04-04 | Pharmaceutical solid composition eliciting anti- arrhythmic activity and method for its preparing |
Publications (2)
Publication Number | Publication Date |
---|---|
RU2207853C1 RU2207853C1 (en) | 2003-07-10 |
RU2002108594A true RU2002108594A (en) | 2003-11-20 |
Family
ID=29211768
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RU2002108594A RU2207853C1 (en) | 2002-04-04 | 2002-04-04 | Pharmaceutical solid composition eliciting anti- arrhythmic activity and method for its preparing |
Country Status (1)
Country | Link |
---|---|
RU (1) | RU2207853C1 (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2632713C2 (en) * | 2016-02-18 | 2017-10-09 | Общество с ограниченной ответственностью "Фармамед" | Delayed release pharmaceutical composition containing asparaginates |
RU2632715C2 (en) * | 2016-03-15 | 2017-10-09 | Общество с ограниченной ответственностью "Фармамед" | Sustained-release pharmaceutical composition containing asparaginates |
EA033102B1 (en) * | 2017-08-21 | 2019-08-30 | Общество с ограниченной ответственностью "Фармамед" | Pharmaceutic composition with modified delayed and sustained release containing asparaginates |
-
2002
- 2002-04-04 RU RU2002108594A patent/RU2207853C1/en active
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