RO86723B - Procedeu pentru prepararea unor derivati de peptide ciclice - Google Patents
Procedeu pentru prepararea unor derivati de peptide cicliceInfo
- Publication number
- RO86723B RO86723B RO110959A RO11095983A RO86723B RO 86723 B RO86723 B RO 86723B RO 110959 A RO110959 A RO 110959A RO 11095983 A RO11095983 A RO 11095983A RO 86723 B RO86723 B RO 86723B
- Authority
- RO
- Romania
- Prior art keywords
- cyclic peptide
- preparation
- peptide derivatives
- acylated
- derivative
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/045—Actinoplanes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/19—Antibiotic
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/27—Cyclic peptide or cyclic protein
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Inventia se refera la un procedeu pentru prepararea unor derivati de peptide ciclice, procedeu ce consta în faptul ca o peptida ciclica ce contine radicali ce sunt independent, hidrogen sau o grupa de protectie amino, este acilata cu un acid de formula generala III: (vezi formula) sau un derivat al acestuia, în mediu de dimetilformamida, la temperatura camerei si sub presiune de azot, si daca se doreste, se îndeparteaza grupele de protectie prezente, dupa reactie.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/380,499 US4396543A (en) | 1982-05-21 | 1982-05-21 | Derivatives of A-21978C cyclic peptides |
Publications (2)
Publication Number | Publication Date |
---|---|
RO86723A RO86723A (ro) | 1985-04-17 |
RO86723B true RO86723B (ro) | 1985-05-01 |
Family
ID=23501405
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RO110959A RO86723B (ro) | 1982-05-21 | 1983-05-16 | Procedeu pentru prepararea unor derivati de peptide ciclice |
Country Status (14)
Country | Link |
---|---|
US (1) | US4396543A (ro) |
KR (1) | KR860002193B1 (ro) |
AT (1) | AT381104B (ro) |
CA (1) | CA1216580A (ro) |
DD (1) | DD210258A5 (ro) |
DK (1) | DK221283A (ro) |
ES (1) | ES522559A0 (ro) |
FI (1) | FI831747L (ro) |
GR (1) | GR78850B (ro) |
HU (1) | HU193528B (ro) |
PH (1) | PH23417A (ro) |
PL (1) | PL242097A1 (ro) |
PT (1) | PT76702B (ro) |
RO (1) | RO86723B (ro) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4977083A (en) * | 1988-04-11 | 1990-12-11 | Eli Lilly And Company | Processes for preparing A54145 compounds |
EP1854877B1 (en) | 1996-03-08 | 2012-02-08 | Astellas Pharma Inc. | Process for the deacylation of cyclic lipopeptides |
EP2295444A3 (en) | 1999-12-15 | 2011-03-23 | Cubist Pharmaceutical Inc. | Lipopeptides as antibacterial agents |
US7408025B2 (en) * | 1999-12-15 | 2008-08-05 | Cubist Pharmaceuticals, Inc. | Lipopeptides as antibacterial agents |
BR0017028A (pt) * | 1999-12-15 | 2003-01-07 | Cubist Pharm Inc | Lipopepìdeos como agentes antibacterianos |
EP1390056B1 (en) * | 2001-04-25 | 2010-03-03 | Wyeth Holdings Corporation | Glycopeptide antibiotics |
CN102325787B (zh) * | 2008-12-22 | 2014-05-28 | 丘比斯特药物股份有限公司 | 治疗革兰氏阳性感染的新的抗菌剂 |
US11174288B2 (en) | 2016-12-06 | 2021-11-16 | Northeastern University | Heparin-binding cationic peptide self-assembling peptide amphiphiles useful against drug-resistant bacteria |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3150059A (en) * | 1962-12-26 | 1964-09-22 | Lilly Co Eli | Penicillin deacylation via actinoplanaceae fermentation |
US4050989A (en) * | 1974-12-05 | 1977-09-27 | Eisai Co., Ltd. | Process of preparing desacyl-pepsidine with bacillus pumilus |
US4208403A (en) * | 1978-10-16 | 1980-06-17 | Eli Lilly And Company | A-21978 Antibiotics and process for their production |
US4293485A (en) * | 1979-12-13 | 1981-10-06 | Eli Lilly And Company | Derivatives of S31794/F-1 nucleus |
US4293491A (en) * | 1979-12-13 | 1981-10-06 | Eli Lilly And Company | Derivatives of A-30912H nucleus |
US4293483A (en) * | 1979-12-13 | 1981-10-06 | Eli Lilly And Company | Derivatives of A-30912A nucleus |
US4293487A (en) * | 1979-12-13 | 1981-10-06 | Eli Lilly And Company | Derivatives of A-30912D nucleus |
US4293482A (en) * | 1979-12-13 | 1981-10-06 | Eli Lilly And Company | A-30912A Nucleus |
US4293488A (en) * | 1979-12-13 | 1981-10-06 | Eli Lilly And Company | Derivatives of A-30912B nucleus |
-
1982
- 1982-05-21 US US06/380,499 patent/US4396543A/en not_active Ceased
-
1983
- 1983-05-13 CA CA000428103A patent/CA1216580A/en not_active Expired
- 1983-05-16 PH PH28905A patent/PH23417A/en unknown
- 1983-05-16 RO RO110959A patent/RO86723B/ro unknown
- 1983-05-16 AT AT0178483A patent/AT381104B/de not_active IP Right Cessation
- 1983-05-16 PT PT76702A patent/PT76702B/pt unknown
- 1983-05-18 FI FI831747A patent/FI831747L/fi not_active Application Discontinuation
- 1983-05-18 DK DK221283A patent/DK221283A/da not_active Application Discontinuation
- 1983-05-19 ES ES522559A patent/ES522559A0/es active Granted
- 1983-05-19 KR KR1019830002223A patent/KR860002193B1/ko active
- 1983-05-19 GR GR71401A patent/GR78850B/el unknown
- 1983-05-20 HU HU831797A patent/HU193528B/hu unknown
- 1983-05-20 DD DD83251130A patent/DD210258A5/de unknown
- 1983-05-20 PL PL24209783A patent/PL242097A1/xx unknown
Also Published As
Publication number | Publication date |
---|---|
PL242097A1 (en) | 1984-07-02 |
CA1216580A (en) | 1987-01-13 |
FI831747A0 (fi) | 1983-05-18 |
AT381104B (de) | 1986-08-25 |
GR78850B (ro) | 1984-10-02 |
PH23417A (en) | 1989-08-07 |
PT76702A (en) | 1983-06-01 |
DK221283A (da) | 1983-11-22 |
PT76702B (en) | 1986-03-27 |
KR840005077A (ko) | 1984-11-03 |
DK221283D0 (da) | 1983-05-18 |
HU193528B (en) | 1987-10-28 |
FI831747L (fi) | 1983-11-22 |
ES8407011A1 (es) | 1984-09-01 |
ATA178483A (de) | 1986-01-15 |
ES522559A0 (es) | 1984-09-01 |
KR860002193B1 (ko) | 1986-12-30 |
RO86723A (ro) | 1985-04-17 |
DD210258A5 (de) | 1984-06-06 |
US4396543A (en) | 1983-08-02 |
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