RO77935A - Procede pour la preparation des cis-4a-arylo tahydro-1h-2-pyrinidine s - Google Patents

Procede pour la preparation des cis-4a-arylo tahydro-1h-2-pyrinidine s

Info

Publication number: RO77935A
Authority: RO; Romania
Prior art keywords: tahydro; pyrinidine; arylo; cis; preparation
Prior art date: 1976-11-02

Application number

RO7799435A

Other languages

English (en)

Romanian (ro)

Inventor

Dennis M Zimmerman

Original Assignee

Eli Lilly And Co,Us

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1976-11-02

Filing date

1977-11-02

Publication date

1981-12-25

1977-11-02 Application filed by Eli Lilly And Co,Us filed Critical Eli Lilly And Co,Us

1981-12-25 Publication of RO77935A publication Critical patent/RO77935A/fr

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/757—Unsaturated compounds containing a keto groups being part of a ring containing —CHO groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/94—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Pain & Pain Management (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Rheumatology (AREA)
Engineering & Computer Science (AREA)
Neurology (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Indole Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Other In-Based Heterocyclic Compounds (AREA)

RO7799435A 1976-11-02 1977-11-02 Procede pour la preparation des cis-4a-arylo tahydro-1h-2-pyrinidine s RO77935A (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US73795876A	1976-11-02	1976-11-02

Publications (1)

Publication Number	Publication Date
RO77935A true RO77935A (fr)	1981-12-25

Family

ID=24965981

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
RO7799434A RO78300A (fr)	1976-11-02	1977-11-02	Procede pour la preparation des cis-4a-aryloctahydro-1h-2-pyrimidines
RO7799435A RO77935A (fr)	1976-11-02	1977-11-02	Procede pour la preparation des cis-4a-arylo tahydro-1h-2-pyrinidine s
RO7792007A RO72900A (fr)	1976-11-02	1977-11-02	Procede pour la preparation des cis-4a-phenyloctahydro-1h-2-pyrindines

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
RO7799434A RO78300A (fr)	1976-11-02	1977-11-02	Procede pour la preparation des cis-4a-aryloctahydro-1h-2-pyrimidines

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
RO7792007A RO72900A (fr)	1976-11-02	1977-11-02	Procede pour la preparation des cis-4a-phenyloctahydro-1h-2-pyrindines

Country Status (26)

Country	Link
JP (1)	JPS5356669A (fr)
AR (1)	AR223454A1 (fr)
AT (1)	ATA782177A (fr)
AU (1)	AU513679B2 (fr)
BE (1)	BE860314A (fr)
CA (1)	CA1100136A (fr)
CS (1)	CS211380B2 (fr)
DD (1)	DD133795A5 (fr)
DE (1)	DE2748466A1 (fr)
DK (1)	DK485277A (fr)
ES (3)	ES463784A1 (fr)
FR (1)	FR2369267A1 (fr)
GB (1)	GB1590155A (fr)
GR (1)	GR70053B (fr)
HU (1)	HU176231B (fr)
IE (1)	IE45901B1 (fr)
IL (1)	IL53236A0 (fr)
NL (1)	NL7712053A (fr)
NZ (1)	NZ185539A (fr)
PH (1)	PH12590A (fr)
PL (3)	PL108466B1 (fr)
PT (1)	PT67194B (fr)
RO (3)	RO78300A (fr)
SE (3)	SE7712218L (fr)
SU (3)	SU812174A3 (fr)
ZA (1)	ZA776497B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NZ189230A (en) *	1977-12-27	1981-05-15	Lilly Co Eli	Trans-4a-aryl-2-substituted-octahydro-1h-2-pyrindines
US4236009A (en) *	1979-06-21	1980-11-25	Eli Lilly And Company	Method of preparing 4A-arylhexahydro-1H-2-pyrindines and 4A-aryloctahydroisoquinolines
US4277608A (en) *	1979-06-21	1981-07-07	Eli Lilly And Company	Method of preparing 4a-arylhexahydro-1H-2-pyrindines and 4a-aryloctahydroisoquinolines
ZA9510829B (en) *	1994-12-23	1996-07-03	Smithkline Beecham Corp	3,3-(disubstituted)cyclohexan-1-one monomers and related compounds
HUE028983T2 (en)	2010-05-06	2017-01-30	Vertex Pharma	Heterocyclic chromene-spirocyclic piperidine amides as ion channel modulators
ES2573497T3 (es)	2011-02-02	2016-06-08	Vertex Pharmaceuticals Incorporated	Pirrolopirazin-amidas de piperidina espirocíclicas como moduladores de canales iónicos
AU2012217616B2 (en)	2011-02-18	2017-03-02	Vertex Pharmaceuticals Incorporated	Chroman - spirocyclic piperidine amides as modulators of ion channels
WO2012125613A1 (fr)	2011-03-14	2012-09-20	Vertex Pharmaceuticals Incorporated	Amides de pipéridine spirocycliques morpholines utilisés en tant que modulateurs de canaux ioniques

1977
- 1977-10-26 PT PT67194A patent/PT67194B/pt unknown
- 1977-10-27 IL IL53236A patent/IL53236A0/xx unknown
- 1977-10-27 NZ NZ185539A patent/NZ185539A/xx unknown
- 1977-10-27 GB GB44729/77A patent/GB1590155A/en not_active Expired
- 1977-10-27 CA CA289,687A patent/CA1100136A/fr not_active Expired
- 1977-10-28 SE SE7712218A patent/SE7712218L/xx unknown
- 1977-10-28 IE IE2206/77A patent/IE45901B1/en unknown
- 1977-10-28 DE DE19772748466 patent/DE2748466A1/de not_active Withdrawn
- 1977-10-28 PH PH20380A patent/PH12590A/en unknown
- 1977-10-28 BE BE1008483A patent/BE860314A/fr unknown
- 1977-10-28 FR FR7732776A patent/FR2369267A1/fr active Granted
- 1977-10-29 GR GR54664A patent/GR70053B/el unknown
- 1977-10-31 AR AR269797A patent/AR223454A1/es active
- 1977-11-01 ZA ZA00776497A patent/ZA776497B/xx unknown
- 1977-11-01 AU AU30235/77A patent/AU513679B2/en not_active Expired
- 1977-11-01 HU HU77EI768A patent/HU176231B/hu unknown
- 1977-11-01 NL NL7712053A patent/NL7712053A/xx not_active Application Discontinuation
- 1977-11-01 DK DK485277A patent/DK485277A/da unknown
- 1977-11-02 SU SU772539649A patent/SU812174A3/ru active
- 1977-11-02 ES ES463784A patent/ES463784A1/es not_active Expired
- 1977-11-02 ES ES463783A patent/ES463783A1/es not_active Expired
- 1977-11-02 DD DD7700201831A patent/DD133795A5/xx unknown
- 1977-11-02 JP JP13211177A patent/JPS5356669A/ja active Pending
- 1977-11-02 RO RO7799434A patent/RO78300A/fr unknown
- 1977-11-02 PL PL1977212226A patent/PL108466B1/pl unknown
- 1977-11-02 RO RO7799435A patent/RO77935A/fr unknown
- 1977-11-02 PL PL1977201885A patent/PL109690B1/pl unknown
- 1977-11-02 PL PL1977212225A patent/PL108610B1/pl unknown
- 1977-11-02 AT AT0782177A patent/ATA782177A/de not_active Application Discontinuation
- 1977-11-02 RO RO7792007A patent/RO72900A/fr unknown
- 1977-11-02 CS CS777150A patent/CS211380B2/cs unknown
1978
- 1978-08-01 ES ES472276A patent/ES472276A1/es not_active Expired
- 1978-10-03 SU SU782669355A patent/SU913941A3/ru active
- 1978-10-03 SU SU782669395A patent/SU845777A3/ru active
1981
- 1981-05-18 SE SE8103107A patent/SE8103107L/sv unknown
- 1981-05-18 SE SE8103106A patent/SE8103106L/sv unknown

Also Published As

Publication number	Publication date
PL108610B1 (en)	1980-04-30
ES463783A1 (es)	1979-07-16
SU913941A3 (en)	1982-03-15
DD133795A5 (de)	1979-01-24
ZA776497B (en)	1979-06-27
ES472276A1 (es)	1979-10-01
NL7712053A (nl)	1978-05-05
FR2369267A1 (fr)	1978-05-26
PH12590A (en)	1979-06-27
PL201885A1 (pl)	1978-12-04
PL109690B1 (en)	1980-06-30
GB1590155A (en)	1981-05-28
FR2369267B1 (fr)	1980-05-16
CA1100136A (fr)	1981-04-28
ATA782177A (de)	1981-10-15
GR70053B (fr)	1982-07-26
JPS5356669A (en)	1978-05-23
HU176231B (en)	1981-01-28
PT67194A (en)	1977-11-01
SE7712218L (sv)	1978-05-03
RO72900A (fr)	1981-11-04
IE45901B1 (en)	1982-12-29
DE2748466A1 (de)	1978-05-03
ES463784A1 (es)	1978-06-16
DK485277A (da)	1978-05-03
CS211380B2 (en)	1982-02-26
SU845777A3 (ru)	1981-07-07
AR223454A1 (es)	1981-08-31
AU3023577A (en)	1979-05-10
IL53236A0 (en)	1977-12-30
SU812174A3 (ru)	1981-03-07
PL108466B1 (en)	1980-04-30
SE8103107L (sv)	1981-05-18
PT67194B (en)	1979-03-23
NZ185539A (en)	1979-12-11
AU513679B2 (en)	1980-12-18
BE860314A (fr)	1978-04-28
IE45901L (en)	1978-05-02
RO78300A (fr)	1982-04-12
SE8103106L (sv)	1981-05-18

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RO71572A (fr)	1982-07-06	Procede pour la preparation des oxycarbamates n-sulphenyles
RO83446A (fr)	1984-02-21	Procede pour la preparation des cyclopropylmethoxyanilides
RO70079A (fr)	1982-10-26	Procede pour la preparation des n-aryle-n-(4-pyperidinyle)-arylacetamides
RO71066A (fr)	1982-10-26	Procede pour la preparation des 2-chlorsulfinylazetidin-4-ones
RO77935A (fr)	1981-12-25	Procede pour la preparation des cis-4a-arylo tahydro-1h-2-pyrinidine s
BE862236A (fr)	1978-06-23	Procede pour la preparation de polyphenols
RO72831A (fr)	1983-08-03	Procede pour la preparation des fenilpyperazines
RO71763A (fr)	1980-12-30	Procede pour la preparation des hydrures de dialkyle-aluminium
PT66890A (fr)	1977-09-01	Procede pour la preparation des aryloxy-1 amino-3 propanols-2
RO70052A (fr)	1980-07-15	Procede pour la preparation des 7-alcoxy-3-chloremethylecephemes
RO72558A (fr)	1982-09-09	Procede pour la preparation des cycloalcanpyrazoles
RO83713A (fr)	1984-05-23	Procede pour la preparation des haloacylamides
RO71742A (fr)	1982-02-26	Procede pour la preparation des 1-oxadethiacephalosporines
RO75074A (fr)	1980-10-30	Procede pour la preparation des thiophenoles
RO81525A (fr)	1983-04-29	Procede pour la preparation des 9-fluor-prednisolones
RO74147A (fr)	1982-10-26	Procede pour la preparation des triazolothienodiazepin-1-ones
FR2338277A1 (fr)	1977-08-12	Procede pour la preparation de la 6-methylpterine
PT66065B (fr)	1978-06-23	Procede pour la preparation de hydrocarbonetes