ATA782177A - Verfahren zur herstellung von neuen cis-4a-aryloctahydro-1h-2-pyrindin-verbindungen sowie der ungiftigen pharmazeutisch annehmbaren saeuread- ditionssalze davon - Google Patents

Verfahren zur herstellung von neuen cis-4a-aryloctahydro-1h-2-pyrindin-verbindungen sowie der ungiftigen pharmazeutisch annehmbaren saeuread- ditionssalze davon

Info

Publication number: ATA782177A
Authority: AT; Austria
Prior art keywords: aryloctahydro; pyrindine; compounds; pharmaceutically acceptable; acid addition
Prior art date: 1976-11-02

Application number

AT0782177A

Other languages

English (en)

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1976-11-02

Filing date

1977-11-02

Publication date

1981-10-15

1977-11-02 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

1981-10-15 Publication of ATA782177A publication Critical patent/ATA782177A/de

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/757—Unsaturated compounds containing a keto groups being part of a ring containing —CHO groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/94—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Pain & Pain Management (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Rheumatology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Other In-Based Heterocyclic Compounds (AREA)
Indole Compounds (AREA)

AT0782177A 1976-11-02 1977-11-02 Verfahren zur herstellung von neuen cis-4a-aryloctahydro-1h-2-pyrindin-verbindungen sowie der ungiftigen pharmazeutisch annehmbaren saeuread- ditionssalze davon ATA782177A (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US73795876A	1976-11-02	1976-11-02

Publications (1)

Publication Number	Publication Date
ATA782177A true ATA782177A (de)	1981-10-15

Family

ID=24965981

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT0782177A ATA782177A (de)	1976-11-02	1977-11-02	Verfahren zur herstellung von neuen cis-4a-aryloctahydro-1h-2-pyrindin-verbindungen sowie der ungiftigen pharmazeutisch annehmbaren saeuread- ditionssalze davon

Country Status (26)

Country	Link
JP (1)	JPS5356669A (de)
AR (1)	AR223454A1 (de)
AT (1)	ATA782177A (de)
AU (1)	AU513679B2 (de)
BE (1)	BE860314A (de)
CA (1)	CA1100136A (de)
CS (1)	CS211380B2 (de)
DD (1)	DD133795A5 (de)
DE (1)	DE2748466A1 (de)
DK (1)	DK485277A (de)
ES (3)	ES463783A1 (de)
FR (1)	FR2369267A1 (de)
GB (1)	GB1590155A (de)
GR (1)	GR70053B (de)
HU (1)	HU176231B (de)
IE (1)	IE45901B1 (de)
IL (1)	IL53236A0 (de)
NL (1)	NL7712053A (de)
NZ (1)	NZ185539A (de)
PH (1)	PH12590A (de)
PL (3)	PL109690B1 (de)
PT (1)	PT67194B (de)
RO (3)	RO78300A (de)
SE (3)	SE7712218L (de)
SU (3)	SU812174A3 (de)
ZA (1)	ZA776497B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NZ189230A (en) *	1977-12-27	1981-05-15	Lilly Co Eli	Trans-4a-aryl-2-substituted-octahydro-1h-2-pyrindines
US4277608A (en) *	1979-06-21	1981-07-07	Eli Lilly And Company	Method of preparing 4a-arylhexahydro-1H-2-pyrindines and 4a-aryloctahydroisoquinolines
US4236009A (en) *	1979-06-21	1980-11-25	Eli Lilly And Company	Method of preparing 4A-arylhexahydro-1H-2-pyrindines and 4A-aryloctahydroisoquinolines
ZA9510829B (en) *	1994-12-23	1996-07-03	Smithkline Beecham Corp	3,3-(disubstituted)cyclohexan-1-one monomers and related compounds
WO2011140425A1 (en)	2010-05-06	2011-11-10	Vertex Pharmaceuticals Incorporated	Heterocyclic chromene-spirocyclic piperidine amides as modulators of ion channels
PT2670752E (pt)	2011-02-02	2016-06-14	Vertex Pharma	Piperidinamidas pirrolopirazina-espirocíclicas como moduladores de canais iónicos
WO2012112743A1 (en)	2011-02-18	2012-08-23	Vertex Pharmaceuticals Incorporated	Chroman - spirocyclic piperidine amides as modulators of ion channels
MX347982B (es)	2011-03-14	2017-05-22	Vertex Pharma	Morfolina-piperidina espirociclica-amidas como moduladores de canales ionicos.

1977
- 1977-10-26 PT PT67194A patent/PT67194B/pt unknown
- 1977-10-27 GB GB44729/77A patent/GB1590155A/en not_active Expired
- 1977-10-27 NZ NZ185539A patent/NZ185539A/xx unknown
- 1977-10-27 IL IL53236A patent/IL53236A0/xx unknown
- 1977-10-27 CA CA289,687A patent/CA1100136A/en not_active Expired
- 1977-10-28 PH PH20380A patent/PH12590A/en unknown
- 1977-10-28 BE BE1008483A patent/BE860314A/xx unknown
- 1977-10-28 FR FR7732776A patent/FR2369267A1/fr active Granted
- 1977-10-28 IE IE2206/77A patent/IE45901B1/en unknown
- 1977-10-28 DE DE19772748466 patent/DE2748466A1/de not_active Withdrawn
- 1977-10-28 SE SE7712218A patent/SE7712218L/xx unknown
- 1977-10-29 GR GR54664A patent/GR70053B/el unknown
- 1977-10-31 AR AR269797A patent/AR223454A1/es active
- 1977-11-01 DK DK485277A patent/DK485277A/da unknown
- 1977-11-01 NL NL7712053A patent/NL7712053A/xx not_active Application Discontinuation
- 1977-11-01 AU AU30235/77A patent/AU513679B2/en not_active Expired
- 1977-11-01 HU HU77EI768A patent/HU176231B/hu unknown
- 1977-11-01 ZA ZA00776497A patent/ZA776497B/xx unknown
- 1977-11-02 JP JP13211177A patent/JPS5356669A/ja active Pending
- 1977-11-02 AT AT0782177A patent/ATA782177A/de not_active Application Discontinuation
- 1977-11-02 CS CS777150A patent/CS211380B2/cs unknown
- 1977-11-02 PL PL1977201885A patent/PL109690B1/pl unknown
- 1977-11-02 RO RO7799434A patent/RO78300A/ro unknown
- 1977-11-02 ES ES463783A patent/ES463783A1/es not_active Expired
- 1977-11-02 PL PL1977212225A patent/PL108610B1/pl unknown
- 1977-11-02 ES ES463784A patent/ES463784A1/es not_active Expired
- 1977-11-02 RO RO7792007A patent/RO72900A/ro unknown
- 1977-11-02 RO RO7799435A patent/RO77935A/ro unknown
- 1977-11-02 PL PL1977212226A patent/PL108466B1/pl unknown
- 1977-11-02 SU SU772539649A patent/SU812174A3/ru active
- 1977-11-02 DD DD7700201831A patent/DD133795A5/de unknown
1978
- 1978-08-01 ES ES472276A patent/ES472276A1/es not_active Expired
- 1978-10-03 SU SU782669355A patent/SU913941A3/ru active
- 1978-10-03 SU SU782669395A patent/SU845777A3/ru active
1981
- 1981-05-18 SE SE8103107A patent/SE8103107L/sv unknown
- 1981-05-18 SE SE8103106A patent/SE8103106L/sv unknown

Also Published As

Publication number	Publication date
AR223454A1 (es)	1981-08-31
JPS5356669A (en)	1978-05-23
PL108466B1 (en)	1980-04-30
IE45901L (en)	1978-05-02
CS211380B2 (en)	1982-02-26
PL201885A1 (pl)	1978-12-04
DE2748466A1 (de)	1978-05-03
BE860314A (fr)	1978-04-28
SE7712218L (sv)	1978-05-03
SU845777A3 (ru)	1981-07-07
HU176231B (en)	1981-01-28
PT67194A (en)	1977-11-01
RO78300A (ro)	1982-04-12
ES472276A1 (es)	1979-10-01
SU812174A3 (ru)	1981-03-07
NL7712053A (nl)	1978-05-05
GB1590155A (en)	1981-05-28
PL108610B1 (en)	1980-04-30
RO77935A (ro)	1981-12-25
FR2369267A1 (fr)	1978-05-26
ZA776497B (en)	1979-06-27
ES463784A1 (es)	1978-06-16
NZ185539A (en)	1979-12-11
IL53236A0 (en)	1977-12-30
IE45901B1 (en)	1982-12-29
SE8103107L (sv)	1981-05-18
PT67194B (en)	1979-03-23
AU3023577A (en)	1979-05-10
SU913941A3 (en)	1982-03-15
DK485277A (da)	1978-05-03
RO72900A (ro)	1981-11-04
SE8103106L (sv)	1981-05-18
GR70053B (de)	1982-07-26
ES463783A1 (es)	1979-07-16
FR2369267B1 (de)	1980-05-16
PL109690B1 (en)	1980-06-30
AU513679B2 (en)	1980-12-18
CA1100136A (en)	1981-04-28
DD133795A5 (de)	1979-01-24
PH12590A (en)	1979-06-27

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Legal Events

Date	Code	Title	Description
1981-11-15	A1AW	Revocation of published examined application