RO71840A - Procedeu de obtinere a unor derivati de chinazolina - Google Patents

Procedeu de obtinere a unor derivati de chinazolina

Info

Publication number
RO71840A
RO71840A RO7589560A RO8956075A RO71840A RO 71840 A RO71840 A RO 71840A RO 7589560 A RO7589560 A RO 7589560A RO 8956075 A RO8956075 A RO 8956075A RO 71840 A RO71840 A RO 71840A
Authority
RO
Romania
Prior art keywords
obtaining
chinazoline derivatives
chinazoline
derivatives
obtaining chinazoline
Prior art date
Application number
RO7589560A
Other languages
English (en)
French (fr)
Inventor
John C Danilewicz
Anthony G Evans
Allan L Ham
Colin Thomson
Original Assignee
Pfizer Corp,Pa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Corp,Pa filed Critical Pfizer Corp,Pa
Publication of RO71840A publication Critical patent/RO71840A/ro

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
RO7589560A 1974-07-25 1975-07-19 Procedeu de obtinere a unor derivati de chinazolina RO71840A (ro)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB3280574 1974-07-25
GB41675*[A GB1460389A (en) 1974-07-25 1975-01-06 4-substituted quinazoline cardiac stimulants

Publications (1)

Publication Number Publication Date
RO71840A true RO71840A (ro) 1982-09-09

Family

ID=26235904

Family Applications (3)

Application Number Title Priority Date Filing Date
RO7589560A RO71840A (ro) 1974-07-25 1975-07-19 Procedeu de obtinere a unor derivati de chinazolina
RO7589559A RO71841A (ro) 1974-07-25 1975-07-19 Procedeu de obtinere a unor derivati de chinazolina cu efect terapeutic
RO7582903A RO69296A (ro) 1974-07-25 1975-07-19 Procedeu pentru prepararea unor derivati chinazolinici

Family Applications After (2)

Application Number Title Priority Date Filing Date
RO7589559A RO71841A (ro) 1974-07-25 1975-07-19 Procedeu de obtinere a unor derivati de chinazolina cu efect terapeutic
RO7582903A RO69296A (ro) 1974-07-25 1975-07-19 Procedeu pentru prepararea unor derivati chinazolinici

Country Status (23)

Country Link
US (1) US4001422A (ro)
JP (1) JPS5527062B2 (ro)
AR (7) AR216046A1 (ro)
BG (2) BG27744A3 (ro)
CA (1) CA1060445A (ro)
CH (2) CH611616A5 (ro)
DD (1) DD119046A5 (ro)
DE (1) DE2530894C2 (ro)
DK (1) DK138800B (ro)
FI (1) FI66182C (ro)
FR (1) FR2279406A1 (ro)
GB (1) GB1460389A (ro)
HK (1) HK61879A (ro)
IE (1) IE41838B1 (ro)
IL (1) IL47625A (ro)
KE (1) KE2988A (ro)
LU (1) LU73072A1 (ro)
MY (1) MY8000108A (ro)
NL (1) NL159982C (ro)
PH (1) PH14190A (ro)
RO (3) RO71840A (ro)
SE (1) SE420921B (ro)
YU (3) YU37155B (ro)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN148482B (ro) 1977-06-03 1981-03-07 Pfizer
US4370328A (en) * 1977-11-03 1983-01-25 Pfizer Inc. Cardiac stimulant 1-(3- or 4-substituted piperidino)phthalazines
CA1086735A (en) * 1977-11-03 1980-09-30 John C. Danilewicz Piperidino-quinazolines
US4489075A (en) * 1982-05-15 1984-12-18 Pfizer Inc. Cyclic sulfonamidoalkyl substituted 4-piperidinoquinazoline cardiac stimulants
JPS61215389A (ja) * 1985-03-20 1986-09-25 Kyowa Hakko Kogyo Co Ltd キナゾリン誘導体およびそれを含有する強心剤
US6645969B1 (en) * 1991-05-10 2003-11-11 Aventis Pharmaceuticals Inc. Aryl and heteroaryl quinazoline compounds which inhibit CSF-1R receptor tyrosine kinase
FR2802206B1 (fr) * 1999-12-14 2005-04-22 Sod Conseils Rech Applic Derives de 4-aminopiperidine et leur utilisation en tant que medicament
TWI283665B (en) * 2001-09-13 2007-07-11 Smithkline Beecham Plc Novel urea compound, pharmaceutical composition containing the same and its use
HUP0200849A2 (hu) * 2002-03-06 2004-08-30 Sanofi-Synthelabo N-aminoacetil-2-ciano-pirrolidin-származékok, e vegyületeket tartalmazó gyógyszerkészítmények és eljárás előállításukra
US7064211B2 (en) * 2002-03-22 2006-06-20 Eisai Co., Ltd. Hemiasterlin derivatives and uses thereof
WO2004024710A1 (en) * 2002-09-13 2004-03-25 Glaxo Group Limited Urea compounds active as vanilloid receptor antagonists for the treatment of pain
TWI350168B (en) 2004-05-07 2011-10-11 Incyte Corp Amido compounds and their use as pharmaceuticals
BRPI0512410A (pt) * 2004-06-24 2008-03-04 Incyte Corp compostos de amido e seu uso como produtos farmacêuticos
CA2589565A1 (en) * 2004-06-24 2006-01-05 Incyte Corporation Amido compounds and their use as pharmaceuticals
CA2570637A1 (en) 2004-06-24 2006-02-02 Wenqing Yao N-substituted piperidines and their use as pharmaceuticals
WO2006002361A2 (en) * 2004-06-24 2006-01-05 Incyte Corporation 2-methylpropanamides and their use as pharmaceuticals
US20060019975A1 (en) * 2004-07-23 2006-01-26 Pfizer Inc Novel piperidyl derivatives of quinazoline and isoquinoline
EP1778229A4 (en) * 2004-08-10 2009-06-17 Incyte Corp AMID COMPOUNDS AND THEIR USE AS MEDICAMENTS
US7825244B2 (en) * 2005-06-10 2010-11-02 Janssen Pharmaceutica Nv Intermediates useful in the synthesis of alkylquinoline and alkylquinazoline kinase modulators, and related methods of synthesis
US8071768B2 (en) * 2005-06-10 2011-12-06 Janssen Pharmaceutica, N.V. Alkylquinoline and alkylquinazoline kinase modulators
TW200808807A (en) * 2006-03-02 2008-02-16 Incyte Corp Modulators of 11-β hydroxyl steroid dehydrogenase type 1, pharmaceutical compositions thereof, and methods of using the same
WO2007103719A2 (en) * 2006-03-03 2007-09-13 Incyte Corporation MODULATORS OF 11-β HYDROXYL STEROID DEHYDROGENASE TYPE 1, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME
US20070293529A1 (en) * 2006-05-01 2007-12-20 Yun-Long Li Tetrasubstituted ureas as modulators of 11-beta hydroxyl steroid dehydrogenase type 1
WO2007137066A2 (en) * 2006-05-17 2007-11-29 Incyte Corporation HETEROCYCLIC INHIBITORS OF 11-β HYDROXYL STEROID DEHYDROGENASE TYPE I AND METHODS OF USING THE SAME
EP1903038A1 (de) * 2006-09-07 2008-03-26 Bayer Schering Pharma Aktiengesellschaft N-(1-Hetaryl-piperidin-4-yl)-(het)arylamide als EP2-Rezeptor Modulatoren
EP1903037A1 (de) * 2006-09-07 2008-03-26 Bayer Schering Pharma Aktiengesellschaft 1-(Het)aryl-3-[hetaryl-piperidin-4-yl]-thioharnstoffe als Modulatoren des EP2-Rezeptors
MA54879A (fr) * 2019-02-01 2021-12-08 Univ Leland Stanford Junior Inhibiteurs d'enpp1 et méthodes de modulation de réponse immunitaire
US11407729B2 (en) 2019-03-19 2022-08-09 Stingray Therapeutics, Inc. Quinoline and quinazoline compounds and methods of use thereof

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1156973A (en) * 1965-07-06 1969-07-02 Quinazoline Derivatives
US3517005A (en) * 1967-10-26 1970-06-23 Pfizer & Co C Certain 2- and 4-substituted quinazolines
US3511836A (en) * 1967-12-13 1970-05-12 Pfizer & Co C 2,4,6,7-tetra substituted quinazolines
US3637701A (en) * 1969-03-03 1972-01-25 Sandoz Ag Certain nitrate derivatives of 4-aminoquinazolines
DE2121031A1 (en) * 1971-04-29 1972-11-02 Dr. Karl Thomae Gmbh, 7950 Biberach Base-substd quinazolines - thrombocyte aggregation inhibitors
BE793371A (fr) * 1971-12-27 1973-06-27 Sandoz Sa Nouveaux derives de la 4-amino-quinazoline, leur preparation etmedicaments contenant ces
US3819628A (en) * 1972-07-31 1974-06-25 Sandoz Ag 2-phenyl-4-substituted amino-quinazolines and nitrates thereof
US3838127A (en) * 1972-10-19 1974-09-24 Sandoz Ag 4-(4-(hydroxyalkyl)-1-piperazino)-quinazoline benzoates
GB1417029A (en) * 1973-03-07 1975-12-10 Pfizer Ltd Quinazoline-derived amines

Also Published As

Publication number Publication date
YU37155B (en) 1984-08-31
HK61879A (en) 1979-09-07
RO69296A (ro) 1981-08-30
YU184275A (en) 1983-04-27
IE41838L (en) 1976-01-25
YU124281A (en) 1983-04-30
NL159982B (nl) 1979-04-17
DK138800C (ro) 1979-04-09
US4001422A (en) 1977-01-04
CH608803A5 (ro) 1979-01-31
FI66182B (fi) 1984-05-31
AR212447A1 (es) 1978-07-14
SE420921B (sv) 1981-11-09
AR214050A1 (es) 1979-04-30
IL47625A0 (en) 1975-10-15
SE7508101L (sv) 1976-01-26
AR214049A1 (es) 1979-04-30
JPS5136469A (ro) 1976-03-27
MY8000108A (en) 1980-12-31
BG27086A3 (ro) 1979-08-15
DE2530894A1 (de) 1976-02-05
GB1460389A (en) 1977-01-06
FI752104A (ro) 1976-01-26
LU73072A1 (ro) 1977-03-24
KE2988A (en) 1979-09-28
FI66182C (fi) 1984-09-10
DK138800B (da) 1978-10-30
CH611616A5 (ro) 1979-06-15
AU8317475A (en) 1977-01-20
DD119046A5 (ro) 1976-04-05
DE2530894C2 (de) 1983-12-22
PH14190A (en) 1981-03-26
YU124181A (en) 1983-04-30
NL159982C (nl) 1979-09-17
DK337175A (ro) 1976-01-26
JPS5527062B2 (ro) 1980-07-17
AR213407A1 (es) 1979-01-31
AR215882A1 (es) 1979-11-15
AR207895A1 (es) 1976-11-08
IE41838B1 (en) 1980-04-09
RO71841A (ro) 1980-08-15
IL47625A (en) 1981-01-30
NL7508824A (nl) 1976-01-27
BG27744A3 (en) 1979-12-12
AR216046A1 (es) 1979-11-30
FR2279406B1 (ro) 1980-04-30
CA1060445A (en) 1979-08-14
FR2279406A1 (fr) 1976-02-20

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