AR213407A1 - Procedimiento para preparar 4-(4-(amino substituido)piperidino)6,7-dimetoxi quinazolinas - Google Patents

Procedimiento para preparar 4-(4-(amino substituido)piperidino)6,7-dimetoxi quinazolinas

Info

Publication number
AR213407A1
AR213407A1 AR263448A AR26344876A AR213407A1 AR 213407 A1 AR213407 A1 AR 213407A1 AR 263448 A AR263448 A AR 263448A AR 26344876 A AR26344876 A AR 26344876A AR 213407 A1 AR213407 A1 AR 213407A1
Authority
AR
Argentina
Prior art keywords
dimetoxy
quinazolines
piperidine
preparing
procedure
Prior art date
Application number
AR263448A
Other languages
English (en)
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of AR213407A1 publication Critical patent/AR213407A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
AR263448A 1974-07-25 1976-05-31 Procedimiento para preparar 4-(4-(amino substituido)piperidino)6,7-dimetoxi quinazolinas AR213407A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB3280574 1974-07-25
GB41675*[A GB1460389A (en) 1974-07-25 1975-01-06 4-substituted quinazoline cardiac stimulants

Publications (1)

Publication Number Publication Date
AR213407A1 true AR213407A1 (es) 1979-01-31

Family

ID=26235904

Family Applications (7)

Application Number Title Priority Date Filing Date
AR259676A AR216046A1 (es) 1974-07-25 1975-07-21 Procedimiento para preparar derivados de (4-piperidino sustituida)6,7-dialcoxi quinazolinas
AR263450A AR207895A1 (es) 1974-07-25 1976-01-01 Procedimiento para preparar un derivado de 4-acetamido piperidino quinazolina
AR263447A AR214049A1 (es) 1974-07-25 1976-05-31 Procedimiento para preparar compuestos de 6,7-dimetoxi-4-(piperidino sustituido)-quinazolinas
AR263448A AR213407A1 (es) 1974-07-25 1976-05-31 Procedimiento para preparar 4-(4-(amino substituido)piperidino)6,7-dimetoxi quinazolinas
AR263451A AR212447A1 (es) 1974-07-25 1976-05-31 Procedimiento para preparar 4-(1,2,3,6-tetrahidropirid-1-il 4-substituido)-6,7-dimetoxiquinazolinas
AR263449A AR214050A1 (es) 1974-07-25 1976-05-31 Procedimiento para preparar compuestos de 6,1-dimetoxi-4-(piperidino sustituido)quinazolina
AR266723A AR215882A1 (es) 1974-07-25 1977-03-01 Procedimiento para la preparacion de 4-piperidino y 4-tetrahidropirido-6,7-dimetoxi-quinazolinas

Family Applications Before (3)

Application Number Title Priority Date Filing Date
AR259676A AR216046A1 (es) 1974-07-25 1975-07-21 Procedimiento para preparar derivados de (4-piperidino sustituida)6,7-dialcoxi quinazolinas
AR263450A AR207895A1 (es) 1974-07-25 1976-01-01 Procedimiento para preparar un derivado de 4-acetamido piperidino quinazolina
AR263447A AR214049A1 (es) 1974-07-25 1976-05-31 Procedimiento para preparar compuestos de 6,7-dimetoxi-4-(piperidino sustituido)-quinazolinas

Family Applications After (3)

Application Number Title Priority Date Filing Date
AR263451A AR212447A1 (es) 1974-07-25 1976-05-31 Procedimiento para preparar 4-(1,2,3,6-tetrahidropirid-1-il 4-substituido)-6,7-dimetoxiquinazolinas
AR263449A AR214050A1 (es) 1974-07-25 1976-05-31 Procedimiento para preparar compuestos de 6,1-dimetoxi-4-(piperidino sustituido)quinazolina
AR266723A AR215882A1 (es) 1974-07-25 1977-03-01 Procedimiento para la preparacion de 4-piperidino y 4-tetrahidropirido-6,7-dimetoxi-quinazolinas

Country Status (23)

Country Link
US (1) US4001422A (es)
JP (1) JPS5527062B2 (es)
AR (7) AR216046A1 (es)
BG (2) BG27744A3 (es)
CA (1) CA1060445A (es)
CH (2) CH608803A5 (es)
DD (1) DD119046A5 (es)
DE (1) DE2530894C2 (es)
DK (1) DK138800B (es)
FI (1) FI66182C (es)
FR (1) FR2279406A1 (es)
GB (1) GB1460389A (es)
HK (1) HK61879A (es)
IE (1) IE41838B1 (es)
IL (1) IL47625A (es)
KE (1) KE2988A (es)
LU (1) LU73072A1 (es)
MY (1) MY8000108A (es)
NL (1) NL159982C (es)
PH (1) PH14190A (es)
RO (3) RO69296A (es)
SE (1) SE420921B (es)
YU (3) YU37155B (es)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN148482B (es) 1977-06-03 1981-03-07 Pfizer
CA1086735A (en) * 1977-11-03 1980-09-30 John C. Danilewicz Piperidino-quinazolines
US4370328A (en) * 1977-11-03 1983-01-25 Pfizer Inc. Cardiac stimulant 1-(3- or 4-substituted piperidino)phthalazines
US4489075A (en) * 1982-05-15 1984-12-18 Pfizer Inc. Cyclic sulfonamidoalkyl substituted 4-piperidinoquinazoline cardiac stimulants
JPS61215389A (ja) * 1985-03-20 1986-09-25 Kyowa Hakko Kogyo Co Ltd キナゾリン誘導体およびそれを含有する強心剤
US6645969B1 (en) * 1991-05-10 2003-11-11 Aventis Pharmaceuticals Inc. Aryl and heteroaryl quinazoline compounds which inhibit CSF-1R receptor tyrosine kinase
FR2802206B1 (fr) * 1999-12-14 2005-04-22 Sod Conseils Rech Applic Derives de 4-aminopiperidine et leur utilisation en tant que medicament
MY138086A (en) * 2001-09-13 2009-04-30 Smithkline Beecham Plc Novel urea derivative as vanilloid receptor-1 antagonist
HUP0200849A2 (hu) * 2002-03-06 2004-08-30 Sanofi-Synthelabo N-aminoacetil-2-ciano-pirrolidin-származékok, e vegyületeket tartalmazó gyógyszerkészítmények és eljárás előállításukra
US7064211B2 (en) * 2002-03-22 2006-06-20 Eisai Co., Ltd. Hemiasterlin derivatives and uses thereof
WO2004024710A1 (en) * 2002-09-13 2004-03-25 Glaxo Group Limited Urea compounds active as vanilloid receptor antagonists for the treatment of pain
TWI350168B (en) 2004-05-07 2011-10-11 Incyte Corp Amido compounds and their use as pharmaceuticals
MXPA06014574A (es) * 2004-06-24 2007-03-12 Incyte Corp Piperidinas n-sustituidas y su uso como farmaceuticos.
AU2005258248A1 (en) * 2004-06-24 2006-01-05 Incyte Corporation Amido compounds and their use as pharmaceuticals
JP2008504279A (ja) * 2004-06-24 2008-02-14 インサイト・コーポレイション アミド化合物およびその医薬としての使用
WO2006002361A2 (en) * 2004-06-24 2006-01-05 Incyte Corporation 2-methylpropanamides and their use as pharmaceuticals
US20060019975A1 (en) * 2004-07-23 2006-01-26 Pfizer Inc Novel piperidyl derivatives of quinazoline and isoquinoline
US20060122197A1 (en) * 2004-08-10 2006-06-08 Wenqing Yao Amido compounds and their use as pharmaceuticals
US7825244B2 (en) * 2005-06-10 2010-11-02 Janssen Pharmaceutica Nv Intermediates useful in the synthesis of alkylquinoline and alkylquinazoline kinase modulators, and related methods of synthesis
US8071768B2 (en) * 2005-06-10 2011-12-06 Janssen Pharmaceutica, N.V. Alkylquinoline and alkylquinazoline kinase modulators
WO2007101270A1 (en) * 2006-03-02 2007-09-07 Incyte Corporation MODULATORS OF 11-β HYDROXYL STEROID DEHYDROGENASE TYPE 1, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME
WO2007103719A2 (en) * 2006-03-03 2007-09-13 Incyte Corporation MODULATORS OF 11-β HYDROXYL STEROID DEHYDROGENASE TYPE 1, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME
CA2649677A1 (en) * 2006-05-01 2007-11-15 Incyte Corporation Tetrasubstituted ureas as modulators of 11-.beta. hydroxyl steroid dehydrogenase type 1
CA2652375A1 (en) * 2006-05-17 2007-11-29 Incyte Corporation Heterocyclic inhibitors of 11-.beta. hydroxyl steroid dehydrogenase type i and methods of using the same
EP1903038A1 (de) * 2006-09-07 2008-03-26 Bayer Schering Pharma Aktiengesellschaft N-(1-Hetaryl-piperidin-4-yl)-(het)arylamide als EP2-Rezeptor Modulatoren
EP1903037A1 (de) * 2006-09-07 2008-03-26 Bayer Schering Pharma Aktiengesellschaft 1-(Het)aryl-3-[hetaryl-piperidin-4-yl]-thioharnstoffe als Modulatoren des EP2-Rezeptors
SG11202108288YA (en) * 2019-02-01 2021-08-30 Univ Leland Stanford Junior Enpp1 inhibitors and methods of modulating immune response
EP3941459A4 (en) * 2019-03-19 2022-11-30 Stingray Therapeutics, Inc. QUINOLINE AND QUINAZOLINE COMPOUNDS AND METHODS OF USE THEREOF

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1156973A (en) * 1965-07-06 1969-07-02 Quinazoline Derivatives
US3517005A (en) * 1967-10-26 1970-06-23 Pfizer & Co C Certain 2- and 4-substituted quinazolines
US3511836A (en) * 1967-12-13 1970-05-12 Pfizer & Co C 2,4,6,7-tetra substituted quinazolines
US3637701A (en) * 1969-03-03 1972-01-25 Sandoz Ag Certain nitrate derivatives of 4-aminoquinazolines
DE2121031A1 (en) * 1971-04-29 1972-11-02 Dr. Karl Thomae Gmbh, 7950 Biberach Base-substd quinazolines - thrombocyte aggregation inhibitors
BE793371A (fr) * 1971-12-27 1973-06-27 Sandoz Sa Nouveaux derives de la 4-amino-quinazoline, leur preparation etmedicaments contenant ces
US3819628A (en) * 1972-07-31 1974-06-25 Sandoz Ag 2-phenyl-4-substituted amino-quinazolines and nitrates thereof
US3838127A (en) * 1972-10-19 1974-09-24 Sandoz Ag 4-(4-(hydroxyalkyl)-1-piperazino)-quinazoline benzoates
GB1417029A (en) * 1973-03-07 1975-12-10 Pfizer Ltd Quinazoline-derived amines

Also Published As

Publication number Publication date
CA1060445A (en) 1979-08-14
GB1460389A (en) 1977-01-06
IL47625A0 (en) 1975-10-15
CH611616A5 (es) 1979-06-15
DK337175A (es) 1976-01-26
BG27086A3 (es) 1979-08-15
DE2530894A1 (de) 1976-02-05
LU73072A1 (es) 1977-03-24
BG27744A3 (en) 1979-12-12
FI66182C (fi) 1984-09-10
AR215882A1 (es) 1979-11-15
RO69296A (ro) 1981-08-30
SE420921B (sv) 1981-11-09
RO71840A (ro) 1982-09-09
MY8000108A (en) 1980-12-31
NL159982C (nl) 1979-09-17
RO71841A (ro) 1980-08-15
AR216046A1 (es) 1979-11-30
YU37155B (en) 1984-08-31
FR2279406A1 (fr) 1976-02-20
AR207895A1 (es) 1976-11-08
AR212447A1 (es) 1978-07-14
CH608803A5 (es) 1979-01-31
FR2279406B1 (es) 1980-04-30
YU124181A (en) 1983-04-30
YU124281A (en) 1983-04-30
AR214050A1 (es) 1979-04-30
NL159982B (nl) 1979-04-17
AU8317475A (en) 1977-01-20
DD119046A5 (es) 1976-04-05
FI66182B (fi) 1984-05-31
DE2530894C2 (de) 1983-12-22
NL7508824A (nl) 1976-01-27
PH14190A (en) 1981-03-26
US4001422A (en) 1977-01-04
IE41838B1 (en) 1980-04-09
HK61879A (en) 1979-09-07
IL47625A (en) 1981-01-30
DK138800C (es) 1979-04-09
KE2988A (en) 1979-09-28
FI752104A (es) 1976-01-26
DK138800B (da) 1978-10-30
AR214049A1 (es) 1979-04-30
JPS5136469A (es) 1976-03-27
IE41838L (en) 1976-01-25
JPS5527062B2 (es) 1980-07-17
YU184275A (en) 1983-04-27
SE7508101L (sv) 1976-01-26

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