RO117145B1 - Emulsie sau soluţie apoasă, mucoadezivă - Google Patents
Emulsie sau soluţie apoasă, mucoadezivăInfo
- Publication number
- RO117145B1 RO117145B1 RO96-02162A RO9602162A RO117145B1 RO 117145 B1 RO117145 B1 RO 117145B1 RO 9602162 A RO9602162 A RO 9602162A RO 117145 B1 RO117145 B1 RO 117145B1
- Authority
- RO
- Romania
- Prior art keywords
- aqueous solution
- emulsion
- mucoadhesive
- mucoadhesive emulsion
- itraconazole
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/40—Cyclodextrins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
- A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nanotechnology (AREA)
- Reproductive Health (AREA)
- Inorganic Chemistry (AREA)
- Gynecology & Obstetrics (AREA)
- Medical Informatics (AREA)
- Urology & Nephrology (AREA)
- Crystallography & Structural Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Endocrinology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
- Adhesives Or Adhesive Processes (AREA)
- Materials For Medical Uses (AREA)
Abstract
Invenţia se referă la emulsie sau soluţie apoasă, mucoadezivă, utilizată în tratamentul medical. Emulsia conform invenţiei este constituită din 10...70% ciclodextrină sau un derivat al acesteia, 0,1...5% itraconazol, 0,05...5% agent de îngroşare, 0,5...10% emulgator, 0,5...10% agent de stabilizare, 0,5...50% ulei acceptabil farmaceutic, un tampon alcătuit din acid sau bază, pentru a menţine pH-ul între 1 şi 4, procentele fiind exprimate în greutate.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP94201402 | 1994-05-18 | ||
PCT/EP1995/001760 WO1995031178A1 (en) | 1994-05-18 | 1995-05-10 | Mucoadhesive emulsions containing cyclodextrin |
Publications (1)
Publication Number | Publication Date |
---|---|
RO117145B1 true RO117145B1 (ro) | 2001-11-30 |
Family
ID=8216883
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RO96-02162A RO117145B1 (ro) | 1994-05-18 | 1995-05-10 | Emulsie sau soluţie apoasă, mucoadezivă |
Country Status (30)
Country | Link |
---|---|
US (1) | US5814330A (ro) |
EP (1) | EP0759741B1 (ro) |
JP (1) | JP3862748B2 (ro) |
KR (1) | KR100369703B1 (ro) |
CN (1) | CN1091590C (ro) |
AP (1) | AP731A (ro) |
AT (1) | ATE174790T1 (ro) |
AU (1) | AU680767B2 (ro) |
BG (1) | BG62754B1 (ro) |
BR (1) | BR9507873A (ro) |
CZ (1) | CZ285606B6 (ro) |
DE (1) | DE69506857T2 (ro) |
DK (1) | DK0759741T3 (ro) |
EE (1) | EE03304B1 (ro) |
ES (1) | ES2127529T3 (ro) |
FI (1) | FI964589A (ro) |
HK (1) | HK1010688A1 (ro) |
HU (1) | HU218082B (ro) |
IL (1) | IL113742A (ro) |
MY (1) | MY113846A (ro) |
NO (1) | NO309507B1 (ro) |
NZ (1) | NZ285761A (ro) |
OA (1) | OA10321A (ro) |
PL (1) | PL179619B1 (ro) |
RO (1) | RO117145B1 (ro) |
RU (1) | RU2164418C2 (ro) |
SK (1) | SK282623B6 (ro) |
TW (1) | TW438601B (ro) |
WO (1) | WO1995031178A1 (ro) |
ZA (1) | ZA954023B (ro) |
Families Citing this family (49)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2188802T3 (es) * | 1995-11-28 | 2003-07-01 | Univ Johns Hopkins Med | Vectores viricos de replicacion condicional y su uso. |
ATE279173T1 (de) * | 1996-10-24 | 2004-10-15 | Procter & Gamble | Verfahren zur verminderung von körpergeruch |
US6416779B1 (en) * | 1997-06-11 | 2002-07-09 | Umd, Inc. | Device and method for intravaginal or transvaginal treatment of fungal, bacterial, viral or parasitic infections |
KR19990001564A (ko) * | 1997-06-16 | 1999-01-15 | 유충식 | 용해도를 개선한 아졸계 항진균제 및 이를 함유하는 제제 |
WO1999033467A1 (en) | 1997-12-31 | 1999-07-08 | Choongwae Pharma Corporation | Method and composition of an oral preparation of itraconazole |
US6683100B2 (en) | 1999-01-19 | 2004-01-27 | Novartis Ag | Organic compounds |
US6194181B1 (en) | 1998-02-19 | 2001-02-27 | Novartis Ag | Fermentative preparation process for and crystal forms of cytostatics |
NZ330726A (en) * | 1998-06-18 | 2000-10-27 | Dec Res | Intra-vaginal delivery unit or composition containing a cyclodextrin which improves absorbtion of 17-beta oestradiol or oestradiol benzoate |
GB9920167D0 (en) * | 1999-08-25 | 1999-10-27 | Avery Dennison Corp | Pressure sensitive adhesive compositions |
AU1911400A (en) * | 1999-11-09 | 2001-06-06 | Procter & Gamble Company, The | Cyclodextrin compositions for odor, insect and dust mite contol |
US6835717B2 (en) * | 2000-03-08 | 2004-12-28 | The Johns Hopkins University School Of Medicine | β-cyclodextrin compositions, and use to prevent transmission of sexually transmitted diseases |
KR100388605B1 (ko) * | 2000-06-13 | 2003-06-25 | 코오롱제약주식회사 | 용해도 및 용해속도가 향상된 이트라코나졸의 액상 조성물 및 이를 이용한 이트라코나졸 제제와 그 제조방법 |
US20020013331A1 (en) | 2000-06-26 | 2002-01-31 | Williams Robert O. | Methods and compositions for treating pain of the mucous membrane |
US7544348B2 (en) | 2001-02-15 | 2009-06-09 | Access Pharmaceuticals, Inc. | Liquid formulations for the prevention and treatment of mucosal diseases and disorders |
NZ549469A (en) | 2001-02-15 | 2009-02-28 | Access Pharma Inc | Liquid formulations for the prevention and treatment of mucosal diseases and disorders |
AU2002350115A1 (en) * | 2001-11-01 | 2003-05-12 | Spectrum Pharmaceuticals, Inc. | Medical compositions for intravesical treatment of bladder cancer |
US8563592B2 (en) | 2001-11-01 | 2013-10-22 | Spectrum Pharmaceuticals, Inc. | Bladder cancer treatment and methods |
CN100384865C (zh) * | 2001-11-02 | 2008-04-30 | 嵌入治疗公司 | 用于rna干扰的治疗用途的方法及组合物 |
US20030144362A1 (en) * | 2002-01-28 | 2003-07-31 | Utterberg David S. | High viscosity antibacterials for cannulae |
US20050042240A1 (en) * | 2002-01-28 | 2005-02-24 | Utterberg David S. | High viscosity antibacterials |
US6899890B2 (en) * | 2002-03-20 | 2005-05-31 | Kv Pharmaceutical Company | Bioadhesive drug delivery system |
US6824763B2 (en) | 2002-05-30 | 2004-11-30 | Kimberly-Clark Worldwide, Inc. | Anti-fungal powder having enhanced excipient properties |
US7977532B2 (en) | 2002-09-05 | 2011-07-12 | The Procter & Gamble Company | Tampon with clean appearance post use |
US20060140990A1 (en) * | 2003-09-19 | 2006-06-29 | Drugtech Corporation | Composition for topical treatment of mixed vaginal infections |
BRPI0414500A (pt) * | 2003-09-19 | 2006-11-07 | Drugtech Corp | formulação farmacêutica composição para tratar uma infecção vaginal, e, métodos para tratar uma infecção vaginal, para estabilizar uma formulação de clindamicina, para tratar ou prevenir uma recorrência de uma infecção vaginal em uma paciente e para tratar condições vaginais |
US20060024372A1 (en) * | 2004-07-29 | 2006-02-02 | Utterberg David S | High viscosity antibacterials |
US9028852B2 (en) | 2004-09-07 | 2015-05-12 | 3M Innovative Properties Company | Cationic antiseptic compositions and methods of use |
US20060275230A1 (en) | 2004-12-10 | 2006-12-07 | Frank Kochinke | Compositions and methods for treating conditions of the nail unit |
CA2590136A1 (en) | 2004-12-10 | 2006-06-15 | Talima Therapeutics, Inc. | Compositions and methods for treating conditions of the nail unit |
AU2006244260A1 (en) * | 2005-05-09 | 2006-11-16 | Drugtech Corporation | Modified-release pharmaceutical compositions |
US8497258B2 (en) | 2005-11-12 | 2013-07-30 | The Regents Of The University Of California | Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract |
US8324192B2 (en) | 2005-11-12 | 2012-12-04 | The Regents Of The University Of California | Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract |
US8679545B2 (en) * | 2005-11-12 | 2014-03-25 | The Regents Of The University Of California | Topical corticosteroids for the treatment of inflammatory diseases of the gastrointestinal tract |
EA200870153A1 (ru) * | 2006-01-05 | 2008-12-30 | Драгтек Корпорейшн | Композиция и способ ее использования |
CA2635994A1 (en) * | 2006-01-05 | 2007-07-12 | Drugtech Corporation | Drug delivery system for bioadhesion to a vulvovaginal surface |
US20100216754A1 (en) * | 2007-11-13 | 2010-08-26 | Meritage Pharma, Inc. | Compositions for the treatment of inflammation of the gastrointestinal tract |
US20090123551A1 (en) * | 2007-11-13 | 2009-05-14 | Meritage Pharma, Inc. | Gastrointestinal delivery systems |
SI3354276T1 (sl) | 2007-11-13 | 2020-09-30 | Meritage Pharma, Inc. | Sestavki za zdravljenje gastrointestinalnega vnetja |
US20090143343A1 (en) * | 2007-11-13 | 2009-06-04 | Meritage Pharma, Inc. | Compositions for the treatment of inflammation of the gastrointestinal tract |
US20090264392A1 (en) * | 2008-04-21 | 2009-10-22 | Meritage Pharma, Inc. | Treating eosinophilic esophagitis |
CN104491864A (zh) | 2008-04-21 | 2015-04-08 | 奥德纳米有限公司 | 用于治疗耳部疾病和病况的耳用调配物及方法 |
US11969501B2 (en) | 2008-04-21 | 2024-04-30 | Dompé Farmaceutici S.P.A. | Auris formulations for treating otic diseases and conditions |
US8784870B2 (en) * | 2008-07-21 | 2014-07-22 | Otonomy, Inc. | Controlled release compositions for modulating free-radical induced damage and methods of use thereof |
EP2306975A4 (en) | 2008-07-21 | 2012-10-31 | Otonomy Inc | CONTROLLED RELEASE COMPOSITIONS MODULATING THE OTIC STRUCTURE AND MODULATING THE NATURAL IMMUNE SYSTEM AND METHODS OF TREATING OTIC DISORDERS |
WO2010021636A1 (en) | 2008-08-20 | 2010-02-25 | The Regents Of The University Of California | Corticosteroids for the treatment of inflammatory diseases of the gastrointestinal tract |
US9498612B2 (en) | 2013-03-14 | 2016-11-22 | Hallux, Inc. | Method of treating infections, diseases or disorders of nail unit |
CA2993645A1 (en) | 2015-07-28 | 2017-02-02 | Otonomy, Inc. | Trkb or trkc agonist compositions and methods for the treatment of otic conditions |
AU2017290256A1 (en) | 2016-06-29 | 2019-01-17 | Otonomy, Inc. | Triglyceride otic formulations and uses thereof |
WO2019154895A1 (en) | 2018-02-08 | 2019-08-15 | Strekin Ag | Gel formulation for preventing or treating hearing loss |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8506792D0 (en) * | 1985-03-15 | 1985-04-17 | Janssen Pharmaceutica Nv | Derivatives of y-cyclodextrin |
ES2058503T5 (es) * | 1988-03-29 | 1999-04-16 | Univ Florida | Formulaciones farmaceuticas para uso parenteral. |
US5055303A (en) * | 1989-01-31 | 1991-10-08 | Kv Pharmaceutical Company | Solid controlled release bioadherent emulsions |
IT1250421B (it) * | 1991-05-30 | 1995-04-07 | Recordati Chem Pharm | Composizione farmaceutica a rilascio controllato con proprieta' bio-adesive. |
ATE138561T1 (de) * | 1992-02-12 | 1996-06-15 | Janssen Cilag S P A | Liposomale itraconazol formulierungen |
US5324718A (en) * | 1992-07-14 | 1994-06-28 | Thorsteinn Loftsson | Cyclodextrin/drug complexation |
FR2719999B1 (fr) * | 1994-05-17 | 1996-08-02 | Georges Serge Grimberg | Composition pharmaceutique à base de gomme de guar et d'un antiacide neutralisant, à laquelle peut être ajoutée une série de principes actifs thérapeutiques. |
-
1995
- 1995-04-14 TW TW084103651A patent/TW438601B/zh not_active IP Right Cessation
- 1995-05-10 EP EP95919433A patent/EP0759741B1/en not_active Expired - Lifetime
- 1995-05-10 EE EE9600212A patent/EE03304B1/xx not_active IP Right Cessation
- 1995-05-10 RO RO96-02162A patent/RO117145B1/ro unknown
- 1995-05-10 KR KR1019960706024A patent/KR100369703B1/ko not_active IP Right Cessation
- 1995-05-10 SK SK1469-96A patent/SK282623B6/sk unknown
- 1995-05-10 ES ES95919433T patent/ES2127529T3/es not_active Expired - Lifetime
- 1995-05-10 PL PL95317257A patent/PL179619B1/pl unknown
- 1995-05-10 AP APAP/P/1996/000873A patent/AP731A/en active
- 1995-05-10 DK DK95919433T patent/DK0759741T3/da active
- 1995-05-10 DE DE69506857T patent/DE69506857T2/de not_active Expired - Lifetime
- 1995-05-10 CZ CZ963369A patent/CZ285606B6/cs not_active IP Right Cessation
- 1995-05-10 BR BR9507873A patent/BR9507873A/pt not_active IP Right Cessation
- 1995-05-10 WO PCT/EP1995/001760 patent/WO1995031178A1/en active IP Right Grant
- 1995-05-10 CN CN95193083A patent/CN1091590C/zh not_active Expired - Lifetime
- 1995-05-10 AU AU25264/95A patent/AU680767B2/en not_active Expired
- 1995-05-10 JP JP52933695A patent/JP3862748B2/ja not_active Expired - Lifetime
- 1995-05-10 NZ NZ285761A patent/NZ285761A/en unknown
- 1995-05-10 US US08/732,262 patent/US5814330A/en not_active Expired - Lifetime
- 1995-05-10 HU HU9603188A patent/HU218082B/hu not_active IP Right Cessation
- 1995-05-10 AT AT95919433T patent/ATE174790T1/de not_active IP Right Cessation
- 1995-05-10 RU RU96123916/14A patent/RU2164418C2/ru active
- 1995-05-16 IL IL11374295A patent/IL113742A/xx not_active IP Right Cessation
- 1995-05-17 ZA ZA954023A patent/ZA954023B/xx unknown
- 1995-05-18 MY MYPI95001311A patent/MY113846A/en unknown
-
1996
- 1996-11-04 BG BG100955A patent/BG62754B1/bg unknown
- 1996-11-08 OA OA60920A patent/OA10321A/en unknown
- 1996-11-15 FI FI964589A patent/FI964589A/fi not_active Application Discontinuation
- 1996-11-15 NO NO964853A patent/NO309507B1/no unknown
-
1998
- 1998-10-27 HK HK98111557A patent/HK1010688A1/xx not_active IP Right Cessation
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