PT95844A - Processo para a preparacao de novas fluoronaftacenodionas, e seus derivados glicosados - Google Patents
Processo para a preparacao de novas fluoronaftacenodionas, e seus derivados glicosadosInfo
- Publication number
- PT95844A PT95844A PT95844A PT9584490A PT95844A PT 95844 A PT95844 A PT 95844A PT 95844 A PT95844 A PT 95844A PT 9584490 A PT9584490 A PT 9584490A PT 95844 A PT95844 A PT 95844A
- Authority
- PT
- Portugal
- Prior art keywords
- new
- alpha
- fluoronaftacenodionas
- preparation
- hydrogen atom
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B35/00—Reactions without formation or introduction of functional groups containing hetero atoms, involving a change in the type of bonding between two carbon atoms already directly linked
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/703—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
- C07C49/747—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/08—Compounds containing oxirane rings with hydrocarbon radicals, substituted by halogen atoms, nitro radicals or nitroso radicals
- C07D303/10—Compounds containing oxirane rings with hydrocarbon radicals, substituted by halogen atoms, nitro radicals or nitroso radicals in which the oxirane rings are condensed with a carbocyclic ring system having three or more relevant rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/26—Radicals substituted by doubly bound oxygen or sulfur atoms or by two such atoms singly bound to the same carbon atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT00956489A IT1236322B (it) | 1989-11-13 | 1989-11-13 | 8-fluoro-antracicline, relativi procedimenti di fabbricazione e loro uso. |
IT9321A IT1239017B (it) | 1990-02-20 | 1990-02-20 | 10-fluoro-antracicline, relativi procedimenti di fabbricazione e loro uso. |
IT9357A IT1238673B (it) | 1990-03-30 | 1990-03-30 | 8-fluoro-4-metossi-antracicline, relativi procedimenti di fabbricazione e loro uso. |
Publications (2)
Publication Number | Publication Date |
---|---|
PT95844A true PT95844A (pt) | 1991-09-13 |
PT95844B PT95844B (pt) | 1997-11-28 |
Family
ID=27272726
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT95844A PT95844B (pt) | 1989-11-13 | 1990-11-09 | Processo para a preparacao de novas fluoronaftacenodionas, e seus derivados glicosados |
Country Status (24)
Country | Link |
---|---|
EP (1) | EP0436474B1 (pt) |
JP (1) | JPH03209343A (pt) |
KR (1) | KR940002983B1 (pt) |
CN (1) | CN1025608C (pt) |
AT (1) | ATE108760T1 (pt) |
AU (1) | AU641702B2 (pt) |
BR (1) | BR9005743A (pt) |
CA (1) | CA2029715A1 (pt) |
CU (1) | CU22303A3 (pt) |
DE (1) | DE69010874T2 (pt) |
DK (1) | DK0436474T3 (pt) |
ES (1) | ES2056433T3 (pt) |
HU (1) | HU208544B (pt) |
IE (1) | IE904002A1 (pt) |
IL (1) | IL96302A0 (pt) |
LV (1) | LV10422A (pt) |
MA (1) | MA21995A1 (pt) |
NO (1) | NO175101C (pt) |
NZ (1) | NZ236032A (pt) |
PL (1) | PL164019B1 (pt) |
PT (1) | PT95844B (pt) |
RU (1) | RU2015958C1 (pt) |
TN (1) | TNSN90131A1 (pt) |
YU (1) | YU47695B (pt) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3943029A1 (de) * | 1989-12-27 | 1991-07-04 | Behringwerke Ag | Verfahren zur herstellung von glycosyl-anthracyclinonen |
CA2121929A1 (en) * | 1994-04-22 | 1995-10-23 | Pierre Doucet | Gear reducer |
IT1271689B (it) * | 1994-08-04 | 1997-06-04 | Menarini Farma Ind | 8-fluoro-antracicline, loro processi di preparazione e composizioni farmaceutiche che le contengono |
AU3923995A (en) * | 1994-11-22 | 1996-06-17 | Novo Nordisk A/S | Active bio-compounds |
WO1999058543A1 (en) * | 1998-05-13 | 1999-11-18 | Instytut Farmaceutyczny | New n-alkyloxycarbonyl derivatives of monosaccharides l-acosamine and l-daunosamine |
KR100932407B1 (ko) * | 2001-10-23 | 2009-12-17 | 다이닛본 스미토모 세이야꾸 가부시끼가이샤 | 염산 암루비신의 안정화 |
US7053191B2 (en) | 2003-05-21 | 2006-05-30 | Solux Corporation | Method of preparing 4-R-substituted 4-demethoxydaunorubicin |
US8357785B2 (en) | 2008-01-08 | 2013-01-22 | Solux Corporation | Method of aralkylation of 4′-hydroxyl group of anthracylins |
US8846882B2 (en) | 2011-04-29 | 2014-09-30 | Synbias Pharma Ag | Method of producing 4-demethoxydaunorubicin |
RU2766222C2 (ru) * | 2017-12-26 | 2022-02-10 | Общество с ограниченной ответственностью "НИАРМЕДИК ФАРМА" | Несимметричные производные полифенолов динафталинового ряда, способ их получения и применение |
CN114230538B (zh) * | 2021-12-21 | 2023-11-17 | 蚌埠医学院 | 一种环系蒽醌类化合物及其制备方法和应用 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8321676D0 (en) * | 1983-08-11 | 1983-09-14 | Erba Farmitalia | 4'-haloanthrocycline glycosides |
US4697005A (en) * | 1985-03-20 | 1987-09-29 | Ohio State University Research Foundation | 1-fluoro, 4-fluoro, and 1,4-difluoro anthracycline anticancer antibiotics |
-
1990
- 1990-11-02 MA MA22269A patent/MA21995A1/fr unknown
- 1990-11-06 IE IE400290A patent/IE904002A1/en unknown
- 1990-11-08 DE DE69010874T patent/DE69010874T2/de not_active Expired - Fee Related
- 1990-11-08 EP EP90830507A patent/EP0436474B1/en not_active Expired - Lifetime
- 1990-11-08 ES ES90830507T patent/ES2056433T3/es not_active Expired - Lifetime
- 1990-11-08 DK DK90830507.1T patent/DK0436474T3/da active
- 1990-11-08 AT AT90830507T patent/ATE108760T1/de not_active IP Right Cessation
- 1990-11-09 YU YU212390A patent/YU47695B/sh unknown
- 1990-11-09 CA CA002029715A patent/CA2029715A1/en not_active Abandoned
- 1990-11-09 IL IL96302A patent/IL96302A0/xx unknown
- 1990-11-09 PT PT95844A patent/PT95844B/pt not_active IP Right Cessation
- 1990-11-12 NZ NZ236032A patent/NZ236032A/xx unknown
- 1990-11-12 AU AU65960/90A patent/AU641702B2/en not_active Ceased
- 1990-11-12 PL PL90287728A patent/PL164019B1/pl unknown
- 1990-11-12 NO NO904907A patent/NO175101C/no unknown
- 1990-11-12 RU SU904831619A patent/RU2015958C1/ru active
- 1990-11-12 HU HU907104A patent/HU208544B/hu not_active IP Right Cessation
- 1990-11-13 JP JP2304175A patent/JPH03209343A/ja active Pending
- 1990-11-13 CU CU90175A patent/CU22303A3/es unknown
- 1990-11-13 CN CN90109104A patent/CN1025608C/zh not_active Expired - Fee Related
- 1990-11-13 BR BR909005743A patent/BR9005743A/pt not_active Application Discontinuation
- 1990-11-13 KR KR1019900018328A patent/KR940002983B1/ko not_active IP Right Cessation
- 1990-11-13 TN TNTNSN90131A patent/TNSN90131A1/fr unknown
-
1993
- 1993-06-22 LV LV930656A patent/LV10422A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
HUT55337A (en) | 1991-05-28 |
NO175101C (no) | 1994-08-31 |
LV10422A (lv) | 1995-02-20 |
HU208544B (en) | 1993-11-29 |
IL96302A0 (en) | 1991-08-16 |
PL287728A1 (en) | 1992-11-02 |
DE69010874T2 (de) | 1994-11-10 |
NO175101B (no) | 1994-05-24 |
NO904907D0 (no) | 1990-11-12 |
KR940002983B1 (ko) | 1994-04-09 |
NO904907L (no) | 1991-05-14 |
ES2056433T3 (es) | 1994-10-01 |
RU2015958C1 (ru) | 1994-07-15 |
CN1025608C (zh) | 1994-08-10 |
BR9005743A (pt) | 1991-09-24 |
EP0436474A1 (en) | 1991-07-10 |
CA2029715A1 (en) | 1991-05-14 |
TNSN90131A1 (fr) | 1991-03-05 |
KR910009613A (ko) | 1991-06-28 |
AU641702B2 (en) | 1993-09-30 |
CU22303A3 (es) | 1995-01-31 |
ATE108760T1 (de) | 1994-08-15 |
EP0436474B1 (en) | 1994-07-20 |
YU212390A (sh) | 1992-12-21 |
DK0436474T3 (da) | 1994-08-29 |
YU47695B (sh) | 1996-01-08 |
AU6596090A (en) | 1991-07-11 |
DE69010874D1 (de) | 1994-08-25 |
PL164019B1 (pl) | 1994-06-30 |
IE904002A1 (en) | 1991-05-22 |
NZ236032A (en) | 1993-09-27 |
JPH03209343A (ja) | 1991-09-12 |
CN1052659A (zh) | 1991-07-03 |
MA21995A1 (fr) | 1991-07-01 |
PT95844B (pt) | 1997-11-28 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EG19555A (en) | Method for preparing of taxol | |
PT88034A (pt) | Processo de preparacao de novos pentassacaridos | |
DE3481514D1 (de) | Neue fructosyltsansferase und verfahren zur herstellung von fructosyl-disacchariden, sowie eine neue halosaccharose. | |
PT95844A (pt) | Processo para a preparacao de novas fluoronaftacenodionas, e seus derivados glicosados | |
PT89120A (pt) | Processo para a preparacao de novos derivados flavonoides 2-piperazinil-2-oxo-etileno substituidos | |
AU575972B2 (en) | 3- aminocarbonylmethoxy - 5 - phenylpyrazole derivatives | |
PT93071A (pt) | Processo para a preparacao de novas 4`-epi-4`-amino-antraciclinas e de composicoes farmaceuticas que as contem | |
ATE112563T1 (de) | Diglycidyläther. | |
IT1237529B (it) | Composti spiro-indolino-ossazine con caratteristiche fotocromatiche e fotosensibilizzatrici e procedimento per la loro preparazione | |
PT90307A (pt) | Processo para a preparacao de sulfonanilidas anti-hipertensivas | |
HUT44997A (en) | Process for producing new cyclopentan derivatives |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
BB1A | Laying open of patent application |
Effective date: 19910404 |
|
FG3A | Patent granted, date of granting |
Effective date: 19970812 |
|
MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 19990228 |