PT88338A - Process for the manufacture of imidazo-benzodiazepines and of pharmaceutical compositions containing the same - Google Patents

Process for the manufacture of imidazo-benzodiazepines and of pharmaceutical compositions containing the same

Info

Publication number
PT88338A
PT88338A PT88338A PT8833888A PT88338A PT 88338 A PT88338 A PT 88338A PT 88338 A PT88338 A PT 88338A PT 8833888 A PT8833888 A PT 8833888A PT 88338 A PT88338 A PT 88338A
Authority
PT
Portugal
Prior art keywords
carbon atoms
alkyl
group
hydrogen
benzodiazepines
Prior art date
Application number
PT88338A
Other languages
English (en)
Other versions
PT88338B (pt
Inventor
Colin Robert Gardner
Charles John Robert Hedegecock
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of PT88338A publication Critical patent/PT88338A/pt
Publication of PT88338B publication Critical patent/PT88338B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Anesthesiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
PT88338A 1987-08-28 1988-08-25 Processo para a preparacao de imidazo-benzodiazepinas e de composicoes farmaceuticas que os contem PT88338B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB878720414A GB8720414D0 (en) 1987-08-28 1987-08-28 Chemical compounds

Publications (2)

Publication Number Publication Date
PT88338A true PT88338A (pt) 1989-06-30
PT88338B PT88338B (pt) 1995-05-04

Family

ID=10623016

Family Applications (1)

Application Number Title Priority Date Filing Date
PT88338A PT88338B (pt) 1987-08-28 1988-08-25 Processo para a preparacao de imidazo-benzodiazepinas e de composicoes farmaceuticas que os contem

Country Status (20)

Country Link
US (1) US4868176A (pt)
EP (1) EP0305298B1 (pt)
JP (1) JPS6471880A (pt)
KR (1) KR890003765A (pt)
AT (1) ATE94878T1 (pt)
AU (1) AU608888B2 (pt)
CA (1) CA1310638C (pt)
DE (1) DE3884319T2 (pt)
DK (1) DK470888A (pt)
ES (1) ES2059551T3 (pt)
FI (1) FI87074C (pt)
GB (2) GB8720414D0 (pt)
HU (1) HU201764B (pt)
IL (1) IL87431A (pt)
MX (1) MX173421B (pt)
NO (1) NO168178C (pt)
NZ (1) NZ225955A (pt)
PT (1) PT88338B (pt)
RU (1) RU2041225C1 (pt)
ZA (1) ZA886209B (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI880814A (fi) * 1987-03-10 1988-09-11 Hoffmann La Roche Imidazodiazepin-derivat.
GB8909700D0 (en) * 1989-04-27 1989-06-14 Roussel Lab Ltd Chemical compounds
GB8927928D0 (en) * 1989-12-11 1990-02-14 Roussel Lab Ltd Chemical compounds
GB9023155D0 (en) * 1990-10-24 1990-12-05 Roussel Lab Ltd Chemical compounds
RU2636785C1 (ru) * 2016-11-21 2017-12-01 федеральное государственное автономное образовательное учреждение высшего образования "Южный федеральный университет" Гидрогалогенид 1-(3,4-диметоксифенил)-2-(7,8-диметил-2,3,4,5-тетрагидро[1,3]диазепино[1,2-а]бензимидазол-11-ил)этанона, обладающий обезболивающей и анксиолитической активностью

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1143728A (en) * 1979-10-04 1983-03-29 Max Gerecke Imidazodiazepine derivatives
MC1528A1 (fr) * 1982-07-21 1984-04-13 Hoffmann La Roche Imidazobenzodiazepines
DK174086D0 (da) * 1986-04-16 1986-04-16 Ferrosan As Nye benzodiazepinderivater samt fremgangsmaade til fremstilling af samme
SU1681729A3 (ru) * 1986-07-25 1991-09-30 Берингер Ингельгейм Кг (Фирма) Способ получени производных 1,4-бензодиазепина

Also Published As

Publication number Publication date
JPS6471880A (en) 1989-03-16
DE3884319D1 (de) 1993-10-28
NZ225955A (en) 1990-08-28
ZA886209B (en) 1989-11-29
PT88338B (pt) 1995-05-04
CA1310638C (en) 1992-11-24
DK470888D0 (da) 1988-08-23
GB8820356D0 (en) 1988-09-28
DK470888A (da) 1989-03-01
RU2041225C1 (ru) 1995-08-09
EP0305298A3 (en) 1990-07-11
FI883965A0 (fi) 1988-08-26
FI87074C (fi) 1992-11-25
ATE94878T1 (de) 1993-10-15
KR890003765A (ko) 1989-04-17
GB2209165A (en) 1989-05-04
FI87074B (fi) 1992-08-14
GB8720414D0 (en) 1987-10-07
NO168178B (no) 1991-10-14
NO168178C (no) 1992-01-22
EP0305298B1 (fr) 1993-09-22
HU201764B (en) 1990-12-28
HUT50474A (en) 1990-02-28
NO883522D0 (no) 1988-08-08
AU2155388A (en) 1989-03-02
EP0305298A2 (fr) 1989-03-01
ES2059551T3 (es) 1994-11-16
MX12857A (es) 1993-10-01
US4868176A (en) 1989-09-19
AU608888B2 (en) 1991-04-18
DE3884319T2 (de) 1994-02-17
FI883965A (fi) 1989-03-01
MX173421B (es) 1994-03-03
GB2209165B (en) 1991-08-14
NO883522L (no) 1989-03-01
IL87431A (en) 1992-11-15
IL87431A0 (en) 1989-01-31

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PT88338A (pt) Process for the manufacture of imidazo-benzodiazepines and of pharmaceutical compositions containing the same
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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19941021

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19960430