PT87573A - Process for the preparation of amidas pyrazine and of pharmaceutical compounds containing them - Google Patents

Process for the preparation of amidas pyrazine and of pharmaceutical compounds containing them

Info

Publication number
PT87573A
PT87573A PT87573A PT8757388A PT87573A PT 87573 A PT87573 A PT 87573A PT 87573 A PT87573 A PT 87573A PT 8757388 A PT8757388 A PT 8757388A PT 87573 A PT87573 A PT 87573A
Authority
PT
Portugal
Prior art keywords
amidas
pyrazine
preparation
compounds containing
pharmaceutical compounds
Prior art date
Application number
PT87573A
Other languages
English (en)
Other versions
PT87573B (pt
Inventor
John Anthony Schwartz
Original Assignee
Ici America Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB878712362A external-priority patent/GB8712362D0/en
Priority claimed from GB888804984A external-priority patent/GB8804984D0/en
Application filed by Ici America Inc filed Critical Ici America Inc
Publication of PT87573A publication Critical patent/PT87573A/pt
Publication of PT87573B publication Critical patent/PT87573B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/16—Halogen atoms; Nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D241/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with nitrogen atoms directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PT87573A 1987-05-26 1988-05-25 Processo para a preparacao de pirazina amidas e de composicoes farmaceuticas que as contem PT87573B (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB878712362A GB8712362D0 (en) 1987-05-26 1987-05-26 Selected pyrazine amides
GB888804984A GB8804984D0 (en) 1988-03-02 1988-03-02 Amides

Publications (2)

Publication Number Publication Date
PT87573A true PT87573A (pt) 1989-05-31
PT87573B PT87573B (pt) 1992-09-30

Family

ID=26292283

Family Applications (1)

Application Number Title Priority Date Filing Date
PT87573A PT87573B (pt) 1987-05-26 1988-05-25 Processo para a preparacao de pirazina amidas e de composicoes farmaceuticas que as contem

Country Status (15)

Country Link
US (1) US4906633A (pt)
EP (1) EP0293171A1 (pt)
JP (1) JPS6452762A (pt)
KR (1) KR880013903A (pt)
CN (1) CN88103112A (pt)
AU (1) AU602770B2 (pt)
DK (1) DK288988A (pt)
FI (1) FI882483A (pt)
GB (1) GB8810934D0 (pt)
HU (1) HU199130B (pt)
NO (1) NO882282L (pt)
PL (1) PL272680A1 (pt)
PT (1) PT87573B (pt)
ZA (1) ZA883500B (pt)
ZW (1) ZW6488A1 (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05134719A (ja) * 1991-11-14 1993-06-01 Nippondenso Co Ltd 異常復帰システム
US5739211A (en) * 1997-02-25 1998-04-14 The Goodyear Tire & Rubber Company Rubber compositions containing a pyrazine amide
UY36034A (es) 2014-03-18 2015-09-30 Astrazeneca Ab Derivados de 3,5-diamino-6-cloro-pirazina-2-carboxamida y sales farmaceuticamente aceptables de estos

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3305552A (en) * 1965-11-22 1967-02-21 Merck & Co Inc 3-aminopyrazinoic acids and process for their preparation
NL6707566A (pt) * 1966-08-17 1968-02-19
US3555024A (en) * 1968-11-13 1971-01-12 Merck & Co Inc 1-(3-aminopyrazinoyl)semicarbazides,1-(3-aminopyrazinoyl) - thiosemicarbazides,and method for their preparation
US3567725A (en) * 1968-11-20 1971-03-02 Merck & Co Inc Process for preparation of 1h-imidazo-(4,5-b)pyrazin-2-ones
US3577418A (en) * 1969-02-12 1971-05-04 Merck & Co Inc Pyrazinamide derivatives and processes for their preparation
US3544568A (en) * 1969-03-18 1970-12-01 Merck & Co Inc 3-amino-5,6-substituted pyrazinamides
US3809721A (en) * 1970-12-23 1974-05-07 Merck & Co Inc Substituted 2-aminomethyl-4,6-disubstituted phenols
US3794734A (en) * 1971-03-03 1974-02-26 Merck & Co Inc Methods of treating edema and hypertension using certain 2-aminoethylphenols
US4041032A (en) * 1974-01-16 1977-08-09 Yamanouchi Pharmaceutical Co., Ltd. Pyrazine derivatives
US3928624A (en) * 1974-04-25 1975-12-23 Merck & Co Inc Phenol compounds in treating pain, fever and inflammation
US4029816A (en) * 1975-11-25 1977-06-14 Merck & Co., Inc. Substituted 2-aminomethyl-6-iodophenols
US4085211A (en) * 1975-12-15 1978-04-18 Merck & Co., Inc. Pyrazinecarboxamides and processes for preparing same
US4115573A (en) * 1977-03-04 1978-09-19 Merck & Co., Inc. N-pyrazinecarbonyl-N'-substituted-sulfamoylguanidine and processes for preparing same
US4272537A (en) * 1980-07-02 1981-06-09 Merck & Co., Inc. 3-Amino-5-substituted-6-halo-N-(4,4-disubstituted-6-substituted-1,3,5-triazin-2-yl)-2-pyrazinecarboxamides
FI820266L (fi) * 1981-02-02 1982-08-03 Ici Plc Alkanolaminderivater
US4550111A (en) * 1982-01-29 1985-10-29 Imperial Chemical Industries Plc Alkanolamine derivatives
GB8810933D0 (en) * 1987-05-26 1988-06-15 Ici America Inc Heterocyclic compounds
GB8812343D0 (en) * 1988-05-25 1988-06-29 Ici America Inc Amino compounds
FI102860B (fi) * 1995-11-07 1999-02-26 Nokia Telecommunications Oy Menetelmä ja järjestelmä elektronisen maksutapahtuman suorittamiseksi

Also Published As

Publication number Publication date
DK288988D0 (da) 1988-05-26
US4906633A (en) 1990-03-06
ZA883500B (pt) 1988-11-28
PT87573B (pt) 1992-09-30
JPS6452762A (en) 1989-02-28
ZW6488A1 (en) 1989-12-20
NO882282D0 (no) 1988-05-25
EP0293171A1 (en) 1988-11-30
HU199130B (en) 1990-01-29
FI882483A0 (fi) 1988-05-26
GB8810934D0 (en) 1988-06-15
DK288988A (da) 1988-11-27
HUT47919A (en) 1989-04-28
KR880013903A (ko) 1988-12-22
AU602770B2 (en) 1990-10-25
PL272680A1 (en) 1989-02-06
FI882483A (fi) 1988-11-27
NO882282L (no) 1988-11-28
CN88103112A (zh) 1988-12-28
AU1644188A (en) 1988-12-01

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19920319

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19930930