PT87573A - Process for the preparation of amidas pyrazine and of pharmaceutical compounds containing them - Google Patents
Process for the preparation of amidas pyrazine and of pharmaceutical compounds containing themInfo
- Publication number
- PT87573A PT87573A PT87573A PT8757388A PT87573A PT 87573 A PT87573 A PT 87573A PT 87573 A PT87573 A PT 87573A PT 8757388 A PT8757388 A PT 8757388A PT 87573 A PT87573 A PT 87573A
- Authority
- PT
- Portugal
- Prior art keywords
- amidas
- pyrazine
- preparation
- compounds containing
- pharmaceutical compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/16—Halogen atoms; Nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D241/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with nitrogen atoms directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB878712362A GB8712362D0 (en) | 1987-05-26 | 1987-05-26 | Selected pyrazine amides |
GB888804984A GB8804984D0 (en) | 1988-03-02 | 1988-03-02 | Amides |
Publications (2)
Publication Number | Publication Date |
---|---|
PT87573A true PT87573A (pt) | 1989-05-31 |
PT87573B PT87573B (pt) | 1992-09-30 |
Family
ID=26292283
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT87573A PT87573B (pt) | 1987-05-26 | 1988-05-25 | Processo para a preparacao de pirazina amidas e de composicoes farmaceuticas que as contem |
Country Status (15)
Country | Link |
---|---|
US (1) | US4906633A (pt) |
EP (1) | EP0293171A1 (pt) |
JP (1) | JPS6452762A (pt) |
KR (1) | KR880013903A (pt) |
CN (1) | CN88103112A (pt) |
AU (1) | AU602770B2 (pt) |
DK (1) | DK288988A (pt) |
FI (1) | FI882483A (pt) |
GB (1) | GB8810934D0 (pt) |
HU (1) | HU199130B (pt) |
NO (1) | NO882282L (pt) |
PL (1) | PL272680A1 (pt) |
PT (1) | PT87573B (pt) |
ZA (1) | ZA883500B (pt) |
ZW (1) | ZW6488A1 (pt) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH05134719A (ja) * | 1991-11-14 | 1993-06-01 | Nippondenso Co Ltd | 異常復帰システム |
US5739211A (en) * | 1997-02-25 | 1998-04-14 | The Goodyear Tire & Rubber Company | Rubber compositions containing a pyrazine amide |
UY36034A (es) | 2014-03-18 | 2015-09-30 | Astrazeneca Ab | Derivados de 3,5-diamino-6-cloro-pirazina-2-carboxamida y sales farmaceuticamente aceptables de estos |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3305552A (en) * | 1965-11-22 | 1967-02-21 | Merck & Co Inc | 3-aminopyrazinoic acids and process for their preparation |
NL6707566A (pt) * | 1966-08-17 | 1968-02-19 | ||
US3555024A (en) * | 1968-11-13 | 1971-01-12 | Merck & Co Inc | 1-(3-aminopyrazinoyl)semicarbazides,1-(3-aminopyrazinoyl) - thiosemicarbazides,and method for their preparation |
US3567725A (en) * | 1968-11-20 | 1971-03-02 | Merck & Co Inc | Process for preparation of 1h-imidazo-(4,5-b)pyrazin-2-ones |
US3577418A (en) * | 1969-02-12 | 1971-05-04 | Merck & Co Inc | Pyrazinamide derivatives and processes for their preparation |
US3544568A (en) * | 1969-03-18 | 1970-12-01 | Merck & Co Inc | 3-amino-5,6-substituted pyrazinamides |
US3809721A (en) * | 1970-12-23 | 1974-05-07 | Merck & Co Inc | Substituted 2-aminomethyl-4,6-disubstituted phenols |
US3794734A (en) * | 1971-03-03 | 1974-02-26 | Merck & Co Inc | Methods of treating edema and hypertension using certain 2-aminoethylphenols |
US4041032A (en) * | 1974-01-16 | 1977-08-09 | Yamanouchi Pharmaceutical Co., Ltd. | Pyrazine derivatives |
US3928624A (en) * | 1974-04-25 | 1975-12-23 | Merck & Co Inc | Phenol compounds in treating pain, fever and inflammation |
US4029816A (en) * | 1975-11-25 | 1977-06-14 | Merck & Co., Inc. | Substituted 2-aminomethyl-6-iodophenols |
US4085211A (en) * | 1975-12-15 | 1978-04-18 | Merck & Co., Inc. | Pyrazinecarboxamides and processes for preparing same |
US4115573A (en) * | 1977-03-04 | 1978-09-19 | Merck & Co., Inc. | N-pyrazinecarbonyl-N'-substituted-sulfamoylguanidine and processes for preparing same |
US4272537A (en) * | 1980-07-02 | 1981-06-09 | Merck & Co., Inc. | 3-Amino-5-substituted-6-halo-N-(4,4-disubstituted-6-substituted-1,3,5-triazin-2-yl)-2-pyrazinecarboxamides |
FI820266L (fi) * | 1981-02-02 | 1982-08-03 | Ici Plc | Alkanolaminderivater |
US4550111A (en) * | 1982-01-29 | 1985-10-29 | Imperial Chemical Industries Plc | Alkanolamine derivatives |
GB8810933D0 (en) * | 1987-05-26 | 1988-06-15 | Ici America Inc | Heterocyclic compounds |
GB8812343D0 (en) * | 1988-05-25 | 1988-06-29 | Ici America Inc | Amino compounds |
FI102860B (fi) * | 1995-11-07 | 1999-02-26 | Nokia Telecommunications Oy | Menetelmä ja järjestelmä elektronisen maksutapahtuman suorittamiseksi |
-
1988
- 1988-05-09 GB GB888810934A patent/GB8810934D0/en active Pending
- 1988-05-16 ZW ZW64/88A patent/ZW6488A1/xx unknown
- 1988-05-17 ZA ZA883500A patent/ZA883500B/xx unknown
- 1988-05-19 AU AU16441/88A patent/AU602770B2/en not_active Ceased
- 1988-05-24 EP EP88304697A patent/EP0293171A1/en not_active Ceased
- 1988-05-25 PL PL27268088A patent/PL272680A1/xx unknown
- 1988-05-25 PT PT87573A patent/PT87573B/pt not_active IP Right Cessation
- 1988-05-25 HU HU882650A patent/HU199130B/hu not_active IP Right Cessation
- 1988-05-25 NO NO882282A patent/NO882282L/no unknown
- 1988-05-26 DK DK288988A patent/DK288988A/da not_active Application Discontinuation
- 1988-05-26 FI FI882483A patent/FI882483A/fi not_active Application Discontinuation
- 1988-05-26 CN CN198888103112A patent/CN88103112A/zh active Pending
- 1988-05-26 US US07/199,082 patent/US4906633A/en not_active Expired - Fee Related
- 1988-05-26 KR KR1019880006197A patent/KR880013903A/ko not_active Application Discontinuation
- 1988-05-26 JP JP63129419A patent/JPS6452762A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
DK288988D0 (da) | 1988-05-26 |
US4906633A (en) | 1990-03-06 |
ZA883500B (pt) | 1988-11-28 |
PT87573B (pt) | 1992-09-30 |
JPS6452762A (en) | 1989-02-28 |
ZW6488A1 (en) | 1989-12-20 |
NO882282D0 (no) | 1988-05-25 |
EP0293171A1 (en) | 1988-11-30 |
HU199130B (en) | 1990-01-29 |
FI882483A0 (fi) | 1988-05-26 |
GB8810934D0 (en) | 1988-06-15 |
DK288988A (da) | 1988-11-27 |
HUT47919A (en) | 1989-04-28 |
KR880013903A (ko) | 1988-12-22 |
AU602770B2 (en) | 1990-10-25 |
PL272680A1 (en) | 1989-02-06 |
FI882483A (fi) | 1988-11-27 |
NO882282L (no) | 1988-11-28 |
CN88103112A (zh) | 1988-12-28 |
AU1644188A (en) | 1988-12-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG3A | Patent granted, date of granting |
Effective date: 19920319 |
|
MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 19930930 |