PT87004A - Process for the preparation of compositions for the treatment of viral infections and composites 3'-azide-2',3'-didesoxy-in osine and 3'-fluoro-2',3'-didesoxyguanosine - Google Patents

Process for the preparation of compositions for the treatment of viral infections and composites 3'-azide-2',3'-didesoxy-in osine and 3'-fluoro-2',3'-didesoxyguanosine

Info

Publication number
PT87004A
PT87004A PT87004A PT8700488A PT87004A PT 87004 A PT87004 A PT 87004A PT 87004 A PT87004 A PT 87004A PT 8700488 A PT8700488 A PT 8700488A PT 87004 A PT87004 A PT 87004A
Authority
PT
Portugal
Prior art keywords
didesoxyguanosine
didesoxy
osine
azide
composites
Prior art date
Application number
PT87004A
Other languages
English (en)
Other versions
PT87004B (pt
Inventor
Fritz Eckstein
Gerhard Hunsmann
Heinz Hartmann
Original Assignee
Max Planck Gesellschaft
Deutsches Primatenzentrum Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19873708849 external-priority patent/DE3708849A1/de
Priority claimed from US07/041,147 external-priority patent/US4880782A/en
Application filed by Max Planck Gesellschaft, Deutsches Primatenzentrum Gmbh filed Critical Max Planck Gesellschaft
Publication of PT87004A publication Critical patent/PT87004A/pt
Publication of PT87004B publication Critical patent/PT87004B/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
PT87004A 1987-03-18 1988-03-17 Processo de preparacao de composicoes para o tratamento de infeccoes virais e de compostos 3'-azido-2',3'-didesoxi-inosina e 3'-fluoro-2',3'-didesoxiguanosina PT87004B (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19873708849 DE3708849A1 (de) 1987-03-18 1987-03-18 Arzneimittel zur behandlung von viruserkrankungen
US07/041,147 US4880782A (en) 1986-11-21 1987-04-22 Method of treating viral infections in humans and compositions therefor

Publications (2)

Publication Number Publication Date
PT87004A true PT87004A (pt) 1988-04-01
PT87004B PT87004B (pt) 1992-06-30

Family

ID=25853652

Family Applications (1)

Application Number Title Priority Date Filing Date
PT87004A PT87004B (pt) 1987-03-18 1988-03-17 Processo de preparacao de composicoes para o tratamento de infeccoes virais e de compostos 3'-azido-2',3'-didesoxi-inosina e 3'-fluoro-2',3'-didesoxiguanosina

Country Status (7)

Country Link
EP (1) EP0286825A3 (pt)
AU (1) AU609099B2 (pt)
DK (1) DK147088A (pt)
HU (1) HU211508A9 (pt)
NO (1) NO881190L (pt)
NZ (1) NZ223865A (pt)
PT (1) PT87004B (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5077279A (en) * 1986-05-01 1991-12-31 University Of Georgia Research Foundation, Inc. 3'-azido-2',3'-dideoxy-5-methylcytidine anti-viral composition
US5084445A (en) * 1986-05-01 1992-01-28 University Of Georgia Research Foundation, Inc. 3'-azido-2',3'-dideoxy-5-methylcytidine
JPH01265099A (ja) * 1987-10-08 1989-10-23 Stichting Rega Vzw 抗ｈｉｖ活性をもつ３’，−フルオロプリン−２’，３’−ジデオキシリボシド類
US5157114A (en) * 1988-08-19 1992-10-20 Burroughs Wellcome Co. 2',3'-dideoxy-3'-fluoro-5-ethyngluridine
SE464168B (sv) * 1989-07-19 1991-03-18 Bo Fredrik Oeberg Antiviral komposition bestaaende av en 3'-fluoro-2',3'-dideoxynukleosidfoerening och en 2',3'-dideoxynukleosidfoerening (exempelvis azt)
KR910007655A (ko) * 1989-10-03 1991-05-30 엠. 피. 잭슨 치료용 뉴클레오시드
JPH05501404A (ja) * 1989-11-06 1993-03-18 ニユコメド・アクシエセルカペト ヌクレオシド誘導体
SE9003151D0 (sv) * 1990-10-02 1990-10-02 Medivir Ab Nucleoside derivatives
GB9105899D0 (en) * 1991-03-20 1991-05-08 Wellcome Found Therapeutic nucleosides
US5869493A (en) 1996-02-16 1999-02-09 Medivir Ab Acyclic nucleoside derivatives

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD209197A1 (de) * 1981-07-21 1984-04-25 Akad Wissenschaften Ddr Verfahren zur herstellung von 3'-fluor-2',3'-didesoxyguanosin
SU1053474A1 (ru) * 1982-02-08 1985-08-07 Институт биоорганической химии АН БССР 3-Фтор-2,3-дидезоксигуанозин,про вл ющий цитостатическую активность
DE3650492T2 (de) * 1985-03-16 1996-10-31 The Wellcome Foundation Ltd., London Therapeutische Nukleoside
US4724232A (en) * 1985-03-16 1988-02-09 Burroughs Wellcome Co. Treatment of human viral infections
GR860712B (en) * 1985-03-16 1986-07-16 Wellcome Found Antiviral compounds
GB2181128A (en) * 1985-09-17 1987-04-15 Wellcome Found 3'-azidonucleosides
DE3739432A1 (de) * 1987-02-24 1989-06-01 Multivac Haggenmueller Kg Verpackungsmaschine

Also Published As

Publication number Publication date
EP0286825A3 (en) 1989-04-12
AU1308188A (en) 1988-09-22
HU211508A9 (en) 1995-11-28
AU609099B2 (en) 1991-04-26
NO881190D0 (no) 1988-03-17
EP0286825A2 (en) 1988-10-19
DK147088A (da) 1988-09-19
DK147088D0 (da) 1988-03-17
PT87004B (pt) 1992-06-30
NO881190L (no) 1988-09-19
NZ223865A (en) 1990-06-26

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19911206

PC3A Transfer or assignment

Free format text: MEDIVIR AB SE

Effective date: 20031031

MM4A Annulment/lapse due to non-payment of fees, searched and examined patent

Free format text: MAXIMUM VALIDITY LIMIT REACHED

Effective date: 20080317