PT859959E - Peptidos que aumentam o transporte atraves dos tecidos e metodos para a sua identificacao e utilizacao - Google Patents

Peptidos que aumentam o transporte atraves dos tecidos e metodos para a sua identificacao e utilizacao

Info

Publication number
PT859959E
PT859959E PT96938439T PT96938439T PT859959E PT 859959 E PT859959 E PT 859959E PT 96938439 T PT96938439 T PT 96938439T PT 96938439 T PT96938439 T PT 96938439T PT 859959 E PT859959 E PT 859959E
Authority
PT
Portugal
Prior art keywords
phage
transported
site
peptide
tissue
Prior art date
Application number
PT96938439T
Other languages
English (en)
Inventor
Daniel Joseph O'mahony
Original Assignee
Elan Corp Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IE950864A external-priority patent/IE80466B1/en
Application filed by Elan Corp Plc filed Critical Elan Corp Plc
Publication of PT859959E publication Critical patent/PT859959E/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • C12N15/1037Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00Libraries per se, e.g. arrays, mixtures
    • C40B40/02Libraries contained in or displayed by microorganisms, e.g. bacteria or animal cells; Libraries contained in or displayed by vectors, e.g. plasmids; Libraries containing only microorganisms or vectors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5082Supracellular entities, e.g. tissue, organisms
    • G01N33/5088Supracellular entities, e.g. tissue, organisms of vertebrates
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983Viruses
PT96938439T 1995-11-10 1996-11-11 Peptidos que aumentam o transporte atraves dos tecidos e metodos para a sua identificacao e utilizacao PT859959E (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IE950864A IE80466B1 (en) 1995-11-10 1995-11-10 Peptides which enhance transport across tissues and methods of identifying and using the same
US646195P 1995-11-13 1995-11-13

Publications (1)

Publication Number Publication Date
PT859959E true PT859959E (pt) 2003-12-31

Family

ID=26319862

Family Applications (1)

Application Number Title Priority Date Filing Date
PT96938439T PT859959E (pt) 1995-11-10 1996-11-11 Peptidos que aumentam o transporte atraves dos tecidos e metodos para a sua identificacao e utilizacao

Country Status (11)

Country Link
EP (3) EP0859959B1 (pt)
JP (3) JP3830525B2 (pt)
AT (1) ATE246808T1 (pt)
AU (2) AU705688B2 (pt)
CA (2) CA2235226A1 (pt)
DE (1) DE69629385T2 (pt)
DK (1) DK0859959T3 (pt)
ES (1) ES2203722T3 (pt)
NZ (2) NZ322174A (pt)
PT (1) PT859959E (pt)
WO (2) WO1997017614A1 (pt)

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US6905686B1 (en) 1997-12-02 2005-06-14 Neuralab Limited Active immunization for treatment of alzheimer's disease
US7790856B2 (en) 1998-04-07 2010-09-07 Janssen Alzheimer Immunotherapy Humanized antibodies that recognize beta amyloid peptide
US6787523B1 (en) 1997-12-02 2004-09-07 Neuralab Limited Prevention and treatment of amyloidogenic disease
US20030147882A1 (en) 1998-05-21 2003-08-07 Alan Solomon Methods for amyloid removal using anti-amyloid antibodies
US7087236B1 (en) 1998-09-01 2006-08-08 Merrion Research I Limited Method for inducing a cell-mediated immune response and improved parenteral vaccine formulations thereof
WO2000014215A1 (de) * 1998-09-07 2000-03-16 Eberhard-Karls-Universität Tübingen Verfahren zur selektion von peptiden für zielgerichteten pharma- und markertransport und peptide damit entdeckt
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AU1174400A (en) * 1998-11-19 2000-06-13 Elan Corporation, Plc Retro-inversion peptides that target git transport receptors and related methods
US6787637B1 (en) 1999-05-28 2004-09-07 Neuralab Limited N-Terminal amyloid-β antibodies
UA81216C2 (en) 1999-06-01 2007-12-25 Prevention and treatment of amyloid disease
ATE363074T1 (de) 1999-09-14 2007-06-15 Xenoport Inc Substrate und screeningverfahren für transportproteine
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US7030219B2 (en) 2000-04-28 2006-04-18 Johns Hopkins University B7-DC, Dendritic cell co-stimulatory molecules
US7700751B2 (en) 2000-12-06 2010-04-20 Janssen Alzheimer Immunotherapy Humanized antibodies that recognize β-amyloid peptide
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BR0307975A (pt) 2002-02-25 2005-01-11 Elan Pharm Inc Métodos para reduzir cronicamente a inflamação patológica em um paciente e para determinar a eficácia de um regime de administração crÈnica para tratar inflamação patológica em um indivìduo, composição e terapia combinada para tratamento crÈnico de inflamação patológica em um paciente e uso de um inibidor de alfa-4-integrina
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WO2010011999A2 (en) 2008-07-25 2010-01-28 The Regents Of The University Of California Methods and compositions for eliciting an amyloid-selective immune response
US7432351B1 (en) 2002-10-04 2008-10-07 Mayo Foundation For Medical Education And Research B7-H1 variants
US8506959B2 (en) 2002-11-01 2013-08-13 Neotope Biosciences Limited Prevention and treatment of synucleinopathic and amyloidogenic disease
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PE20050627A1 (es) 2003-05-30 2005-08-10 Wyeth Corp Anticuerpos humanizados que reconocen el peptido beta amiloideo
PL2336147T3 (pl) 2003-12-17 2015-01-30 Janssen Alzheimer Immunotherap Immunogenne koniugaty A beta z nośnikiem peptydowym i sposoby ich otrzymywania
HUE026000T2 (en) 2003-12-17 2016-04-28 Wyeth Llc Immunogenic peptide-bearing conjugates and methods for their preparation
MX2007001679A (es) 2004-08-09 2007-05-23 Elan Pharm Inc Prevencion y tratamiento de la enfermedad sinucleinopatica y amiloidogenica.
JP5303146B2 (ja) 2004-10-06 2013-10-02 メイヨ・ファウンデーション・フォー・メディカル・エデュケーション・アンド・リサーチ B7−h1ならびに癌の診断、予後診断および処置の方法
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US7989173B2 (en) 2006-12-27 2011-08-02 The Johns Hopkins University Detection and diagnosis of inflammatory disorders
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WO2008084899A1 (en) * 2007-01-10 2008-07-17 Insilicotech Co., Ltd. The enterocyte-transcytotic, tissue target and m cell target peptide identified by the phage display process and drug delivery systems using the same
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US8003097B2 (en) 2007-04-18 2011-08-23 Janssen Alzheimer Immunotherapy Treatment of cerebral amyloid angiopathy
PL2182983T3 (pl) 2007-07-27 2014-10-31 Janssen Alzheimer Immunotherap Leczenie chorób amyloidowych z wykorzystaniem humanizowanych przeciwciał specyficznych względem Abeta
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US8619257B2 (en) * 2007-12-13 2013-12-31 Kimberley-Clark Worldwide, Inc. Recombinant bacteriophage for detection of nosocomial infection
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WO2015075635A2 (en) 2013-11-19 2015-05-28 Prothena Biosciences Limited Monitoring immunotherapy of lewy body disease from constipation symptoms
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CN109715823A (zh) * 2016-04-08 2019-05-03 美国冷泉港实验室 通过测序进行的神经元投射的多重分析
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UA127808C2 (uk) 2018-04-12 2024-01-10 ЕйСей РендД МЕНЕДЖМЕНТ КО., ЛТД. Похідна пладієноліду (варіанти) як засіб, що здійснює цілеспрямований вплив на сплайсосому, для лікування раку
CN112367996A (zh) 2018-06-01 2021-02-12 卫材R&D管理有限公司 使用剪接调节剂的方法
JP7390315B2 (ja) 2018-06-01 2023-12-01 エーザイ・アール・アンド・ディー・マネジメント株式会社 スプライシング調節薬抗体-薬物コンジュゲート及びその使用方法
JP7365766B2 (ja) 2018-11-16 2023-10-20 住友重機械工業株式会社 偏心揺動型減速装置
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Also Published As

Publication number Publication date
JP3830525B2 (ja) 2006-10-04
DE69629385D1 (de) 2003-09-11
JP2002515967A (ja) 2002-05-28
EP0876615A1 (en) 1998-11-11
ATE246808T1 (de) 2003-08-15
JP2002504072A (ja) 2002-02-05
WO1997017613A1 (en) 1997-05-15
DE69629385T2 (de) 2004-06-09
EP1281718A3 (en) 2005-01-19
JP2006117686A (ja) 2006-05-11
CA2235226A1 (en) 1997-05-15
NZ322174A (en) 1999-02-25
JP4126055B2 (ja) 2008-07-30
DK0859959T3 (da) 2003-11-24
EP0859959A1 (en) 1998-08-26
CA2234685A1 (en) 1997-05-15
AU705688B2 (en) 1999-05-27
NZ322175A (en) 1999-02-25
EP1281718A2 (en) 2003-02-05
AU7585296A (en) 1997-05-29
WO1997017614A1 (en) 1997-05-15
ES2203722T3 (es) 2004-04-16
JP4135978B2 (ja) 2008-08-20
AU705816B2 (en) 1999-06-03
AU7585396A (en) 1997-05-29
EP0859959B1 (en) 2003-08-06

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