PT84007B - Processo para a preparacao de novos derivados de {{4-{4-(4-fenil-1-piperazinil)fenoximetil}-1,3-dioxolan-2-il}metil}-1h-imidazois e 1h-1,2,4-triazois e de composicoes anti-fungicidas e anti-bactericidas que as contem - Google Patents

Processo para a preparacao de novos derivados de {{4-{4-(4-fenil-1-piperazinil)fenoximetil}-1,3-dioxolan-2-il}metil}-1h-imidazois e 1h-1,2,4-triazois e de composicoes anti-fungicidas e anti-bactericidas que as contem

Info

Publication number
PT84007B
PT84007B PT84007A PT8400786A PT84007B PT 84007 B PT84007 B PT 84007B PT 84007 A PT84007 A PT 84007A PT 8400786 A PT8400786 A PT 8400786A PT 84007 B PT84007 B PT 84007B
Authority
PT
Portugal
Prior art keywords
compounds
triazois
pyerazinyl
imidazoes
bacterycides
Prior art date
Application number
PT84007A
Other languages
English (en)
Other versions
PT84007A (en
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of PT84007A publication Critical patent/PT84007A/pt
Publication of PT84007B publication Critical patent/PT84007B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
PT84007A 1985-12-23 1986-12-23 Processo para a preparacao de novos derivados de {{4-{4-(4-fenil-1-piperazinil)fenoximetil}-1,3-dioxolan-2-il}metil}-1h-imidazois e 1h-1,2,4-triazois e de composicoes anti-fungicidas e anti-bactericidas que as contem PT84007B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US81267085A 1985-12-23 1985-12-23

Publications (2)

Publication Number Publication Date
PT84007A PT84007A (en) 1987-01-01
PT84007B true PT84007B (pt) 1989-06-30

Family

ID=25210297

Family Applications (1)

Application Number Title Priority Date Filing Date
PT84007A PT84007B (pt) 1985-12-23 1986-12-23 Processo para a preparacao de novos derivados de {{4-{4-(4-fenil-1-piperazinil)fenoximetil}-1,3-dioxolan-2-il}metil}-1h-imidazois e 1h-1,2,4-triazois e de composicoes anti-fungicidas e anti-bactericidas que as contem

Country Status (18)

Country Link
EP (1) EP0228125B1 (pt)
JP (2) JPH0749428B2 (pt)
AT (1) ATE73799T1 (pt)
AU (2) AU589726B2 (pt)
CA (1) CA1292472C (pt)
CY (1) CY1825A (pt)
DE (1) DE3684431D1 (pt)
DK (2) DK164167C (pt)
ES (1) ES2032381T3 (pt)
FI (1) FI88505C (pt)
GR (1) GR3004114T3 (pt)
HK (1) HK46295A (pt)
IE (1) IE59564B1 (pt)
IL (1) IL81054A (pt)
NO (1) NO167917C (pt)
NZ (1) NZ218553A (pt)
PT (1) PT84007B (pt)
ZA (1) ZA869637B (pt)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ223799A (en) * 1987-03-25 1989-12-21 Janssen Pharmaceutica Nv Azolylmethyl-dioxolanylmethoxyphenyl-piperazinyl-phenyl-triazolones and antimicrobial compositions
CA1331757C (en) * 1988-02-29 1994-08-30 Janssen Pharmaceutica Naamloze Vennootschap 5-lipoxygenase inhibiting 4-(4-phenyl-1-piperazinyl)phenols
GR1000297B (el) * 1988-07-01 1992-05-12 Janssen Pharmaceutica Nv Μεθοδος παρασκευης παραγωγων 2,4-διυδρο-3η-1,2,4-τριαζολ-3-ονης.
GR1000330B (el) * 1988-07-01 1992-06-25 Janssen Pharmaceutica Nv Μεθοδος παρασκευης παραγωγων 2,4 διυδρο-3η-1,2,4-τριαζολ-3-ονης.
GR1000302B (el) * 1988-07-01 1992-05-12 Janssen Pharmaceutica Nv Μεθοδος παρασκευης παραγωγων 2,4-διυδρο-3η-1,2,4-τριαζολ-3-ονης.
GR1000298B (el) * 1988-07-01 1992-05-12 Janssen Pharmaceutica Nv Μεθοδος παρασκευης παραγωγων 2,4-διυδρο-3η-1,2,4-τριαζολ-3-ονης.
GB8903592D0 (en) * 1989-02-16 1989-04-05 Boots Co Plc Therapeutic agents
NZ233502A (en) * 1989-06-09 1991-11-26 Janssen Pharmaceutica Nv 4-(1,2,4-triazole- or imidazole-phenyl-substituted) -1-(1,3-dioxolan-4-ylmethoxyphenyl) piperazine derivatives; preparatory processes: fungicidal and antiviral compositions
CA2076257A1 (en) * 1991-09-13 1993-03-14 Jan Heeres 4-¬4-¬4-(4-hydroxyphenyl)-1- piperazinyl|phenyl|-5-methyl-3h -1,2,4-triazol-3-one derivatives
TW279864B (pt) * 1993-02-19 1996-07-01 Janssen Pharmaceutica Nv
WO1995017407A1 (en) * 1993-12-21 1995-06-29 Schering Corporation Tetrahydrofuran antifungals
KR100352147B1 (ko) * 1994-01-24 2002-11-11 얀센 파마슈티카 엔.브이. 수용성아졸항진균제
US5571811A (en) * 1994-07-12 1996-11-05 Janssen Pharmaceutica N.V. Sulfonamide derivatives of azolones
DK0788496T3 (da) * 1994-10-27 2001-06-18 Janssen Pharmaceutica Nv Inhibitorer for syntese af apolipoprotein-B
US5625064A (en) * 1995-04-19 1997-04-29 Schering Corporation Process for the preparation of triazolones
TW457240B (en) * 1995-04-20 2001-10-01 Janssen Pharmaceutica Nv Novel triazolones as apolipoprotein-B synthesis inhibitors
AU6257596A (en) * 1995-06-19 1997-01-15 Schering Corporation Hydroxyalkyl-substituted triazolones antifungals
JP2001504121A (ja) * 1996-11-12 2001-03-27 セプラコール，インク． ２ｒ，４ｓ，ｒ，ｓ―および２ｓ，４ｒ，ｒ，ｓ―ヒドロキシイトラコナゾール―およびヒドロキシサパーコナゾール誘導体
AU773405B2 (en) * 1996-11-12 2004-05-27 Sepracor, Inc. Hydroxyitraconazole enantiomer mixtures
UA63954C2 (en) * 1997-07-11 2004-02-16 Janssen Pharmaceutica Nv (+/-) norcisapride, a process for the preparation thereof, intermediate compounds, composition based thereon for use in the manufacture of medicaments for treating gastro-intestinal disorders
TW593312B (en) 1997-07-11 2004-06-21 Janssen Pharmaceutica Nv 2,4,4-trisubstituted-1,3-dioxolane antifungals
WO1999018111A1 (en) * 1997-10-07 1999-04-15 Schering Corporation Crystalline antifungal glycine ester polymorph
CZ20013866A3 (cs) 1999-05-04 2002-06-12 Janssen Pharmaceutica N. V. Antifungální ethery
KR100342383B1 (ko) * 1999-06-17 2002-12-06 한국화학연구원 이소옥사졸리딘 유도체, 그의 제조 방법 및 그를 포함하는 살균제 조성물
BR112012029227B1 (pt) * 2010-05-19 2020-01-07 Sandoz Ag Processo para a preparação de um composto quiral, composto quiral e uso de um composto
WO2016087880A1 (en) 2014-12-05 2016-06-09 Pulmocide Limited Antimycotic compound
CA2981945C (en) 2015-05-21 2023-08-29 Pulmocide Limited Antifungal 4-(4-(4-(((3r,5r)-5-((1 h-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)-3-methylphenyl)piperazin-1-yl)-n-(2-hydroxycyclohexyl) benzamide, or a pharmaceutically acceptable salt thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4144346A (en) * 1977-01-31 1979-03-13 Janssen Pharmaceutica N.V. Novel 1-(1,3-dioxolan-2-ylmethyl)-1H-imidazoles
US4267179A (en) * 1978-06-23 1981-05-12 Janssen Pharmaceutica, N.V. Heterocyclic derivatives of (4-phenylpiperazin-1-yl-aryloxymethyl-1,3-dioxolan-2-yl)methyl-1H-imidazoles and 1H-1,2,4-triazoles
US4619931A (en) * 1983-02-28 1986-10-28 Janssen Pharmaceutica, N.V. [[4-[4-(4-phenyl-1-piperazinyl)phenoxymethyl]-1,3-dioxolan-2-yl]methyl]-1H-imidazoles and 1H-1,2,4-triazoles

Also Published As

Publication number Publication date
CA1292472C (en) 1991-11-26
DK74691A (da) 1991-04-23
CY1825A (en) 1995-12-01
FI865257A (fi) 1987-06-24
IE59564B1 (en) 1994-03-09
DK74691D0 (da) 1991-04-23
NZ218553A (en) 1990-06-26
PT84007A (en) 1987-01-01
JP2574656B2 (ja) 1997-01-22
DK164167C (da) 1992-10-12
HK46295A (en) 1995-04-07
ATE73799T1 (de) 1992-04-15
JPS62158275A (ja) 1987-07-14
JPH07285963A (ja) 1995-10-31
IE863369L (en) 1987-06-23
NO167917B (no) 1991-09-16
DK164167B (da) 1992-05-18
DK625586A (da) 1987-06-24
IL81054A0 (en) 1987-03-31
AU593736B2 (en) 1990-02-15
FI88505B (fi) 1993-02-15
DK625586D0 (da) 1986-12-22
NO865235L (no) 1987-06-24
AU589726B2 (en) 1989-10-19
EP0228125B1 (en) 1992-03-18
NO167917C (no) 1991-12-27
IL81054A (en) 1992-03-29
GR3004114T3 (pt) 1993-03-31
NO865235D0 (no) 1986-12-22
JPH0749428B2 (ja) 1995-05-31
FI865257A0 (fi) 1986-12-22
DE3684431D1 (de) 1992-04-23
ES2032381T3 (es) 1993-02-16
FI88505C (fi) 1993-05-25
AU1607688A (en) 1988-08-04
DK167356B1 (da) 1993-10-18
AU6685386A (en) 1987-06-25
EP0228125A1 (en) 1987-07-08
ZA869637B (en) 1988-08-31

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