PT83636B - Processo para a preparacao de 5-aril-2,4-dialquil-3h-1,2,4-triazole-3-tionas - Google Patents

Processo para a preparacao de 5-aril-2,4-dialquil-3h-1,2,4-triazole-3-tionas

Info

Publication number
PT83636B
PT83636B PT83636A PT8363686A PT83636B PT 83636 B PT83636 B PT 83636B PT 83636 A PT83636 A PT 83636A PT 8363686 A PT8363686 A PT 8363686A PT 83636 B PT83636 B PT 83636B
Authority
PT
Portugal
Prior art keywords
dialquil
tions
triazole
aryl
preparation
Prior art date
Application number
PT83636A
Other languages
English (en)
Other versions
PT83636A (en
Inventor
Francis Peter Miller
John Michael Kane
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of PT83636A publication Critical patent/PT83636A/pt
Publication of PT83636B publication Critical patent/PT83636B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D249/12—Oxygen or sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, ***e
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PT83636A 1985-10-29 1986-10-28 Processo para a preparacao de 5-aril-2,4-dialquil-3h-1,2,4-triazole-3-tionas PT83636B (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US79235985A 1985-10-29 1985-10-29
US80761385A 1985-12-11 1985-12-11

Publications (2)

Publication Number Publication Date
PT83636A PT83636A (en) 1986-11-01
PT83636B true PT83636B (pt) 1988-10-14

Family

ID=27121269

Family Applications (1)

Application Number Title Priority Date Filing Date
PT83636A PT83636B (pt) 1985-10-29 1986-10-28 Processo para a preparacao de 5-aril-2,4-dialquil-3h-1,2,4-triazole-3-tionas

Country Status (19)

Country Link
EP (1) EP0221485B1 (pt)
JP (1) JPH07116162B2 (pt)
KR (1) KR900003879B1 (pt)
CN (1) CN1014993B (pt)
AR (1) AR243171A1 (pt)
AU (1) AU587646B2 (pt)
CA (2) CA1284997C (pt)
DE (1) DE3676632D1 (pt)
DK (1) DK164785C (pt)
ES (1) ES2031449T3 (pt)
FI (1) FI89047C (pt)
GR (1) GR3001246T3 (pt)
HU (1) HU196191B (pt)
IE (1) IE58969B1 (pt)
IL (1) IL80434A (pt)
NO (1) NO165542C (pt)
NZ (1) NZ218087A (pt)
PH (2) PH22377A (pt)
PT (1) PT83636B (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR243169A1 (es) * 1985-10-29 1993-07-30 Merrell Pharma Inc Procedimiento para preparar 5-naftil-2,4-dialquil-3h-1,2,4-triazol-3-tionas.
JP2542880B2 (ja) * 1986-12-19 1996-10-09 メレルダウファーマスーティカルズ インコーポレーテッド ５−アリ―ル−３ｈ−１，２，４，−トリアゾ―ル−３−オン類の抗痙攣剤としての用途
JP2593084B2 (ja) * 1986-12-19 1997-03-19 メレルダウファーマスーティカルズ インコーポレーテッド ５−アリールー３ｈ−１，２，４−トリアゾールー３−オン類の神経変性障害の処置への用途
EP0280867A1 (en) * 1987-01-27 1988-09-07 Merrell Dow Pharmaceuticals Inc. Process for the preparation of 5-aryl-2,4-dialkyl-3H-1,2,4-triazole-3-thiones
US4847276A (en) * 1988-09-06 1989-07-11 Merrell Dow Pharmaceuticals Inc. Treatment of thromobocytosis with 5-(4-chlorophenyl)-2,4-diemthyl-3H-1,2,4-triazole-3-thione
CN1046273C (zh) * 1993-10-29 1999-11-10 默里尔药物公司 用作记忆增强剂的3－芳基－4－烷基及4,5－二烷基－4h－1,2,4－***
AU700620B2 (en) * 1994-07-07 1999-01-07 Merrell Pharmaceuticals Inc. Process for the preparation of 5-aryl-2,4-dialkyl-3 h-1,2,4-triazole-3-thiones

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR243169A1 (es) * 1985-10-29 1993-07-30 Merrell Pharma Inc Procedimiento para preparar 5-naftil-2,4-dialquil-3h-1,2,4-triazol-3-tionas.
DK570987A (da) * 1986-12-01 1988-06-02 Hoffmann La Roche Oxadiazol-, thiadiazol- og triazolforbindelser

Also Published As

Publication number Publication date
NZ218087A (en) 1989-05-29
DK164785B (da) 1992-08-17
GR3001246T3 (en) 1992-07-30
DK514886A (da) 1987-04-30
AR243171A1 (es) 1993-07-30
HUT45030A (en) 1988-05-30
CN1014993B (zh) 1991-12-04
JPS62106085A (ja) 1987-05-16
PT83636A (en) 1986-11-01
EP0221485A1 (en) 1987-05-13
CA1284997C (en) 1991-06-18
PH23275A (en) 1989-06-23
NO165542C (no) 1991-02-27
CA1301655C (en) 1992-05-26
IE58969B1 (en) 1993-12-01
NO165542B (no) 1990-11-19
IL80434A (en) 1991-01-31
FI864377A0 (fi) 1986-10-28
FI89047C (fi) 1993-08-10
NO864306D0 (no) 1986-10-28
HU196191B (en) 1988-10-28
NO864306L (no) 1987-04-30
AU6438686A (en) 1987-04-30
EP0221485B1 (en) 1990-12-27
JPH07116162B2 (ja) 1995-12-13
DE3676632D1 (de) 1991-02-07
PH22377A (en) 1988-08-12
KR900003879B1 (ko) 1990-06-04
IE862832L (en) 1987-04-29
FI89047B (fi) 1993-04-30
DK514886D0 (da) 1986-10-28
CN86106880A (zh) 1987-06-10
IL80434A0 (en) 1987-01-30
FI864377A (fi) 1987-04-30
KR870004006A (ko) 1987-05-06
ES2031449T3 (es) 1992-12-16
DK164785C (da) 1992-12-28
AU587646B2 (en) 1989-08-24

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Effective date: 20000930